Selective Synthesis of Primary Amines Directly from Alcohols and Ammonia

著者: Chidambaram Gunanathan, David Milstein - Angewandte Chemie International Edition 2008 被引用: 517

Air stable and waterproof: Selective and efficient synthesis of primary amines directly from alcohols and ammonia is achieved under mild conditions (see scheme). The reaction is homogenously catalyzed by a novel air-stable ruthenium pincer complex and can proceed in toluene or even in the absence of solvent or “on water”.