Dysfunction of estrogen-related receptor alpha-dependent hepatic VLDL secretion contributes to sex disparity in NAFLD/NASH development

著者: Meng Yang, Qingli Liu, Tongling Huang, Wenjuan Tan, Linbing Qu, Tianke Chen, Haobo Pan, Ling Chen, Jinsong Liu, Chi‐Wai Wong, William W. Lu, Min Guan - Theranostics 2020 被引用: 85

Our results highlight ERRα as a key mediator which contributes to the sex disparity in NAFLD development, suggesting that selectively restoring ERRα activity in the liver may be a novel strategy for treating NAFLD/NASH.