Deblur Rapidly Resolves Single-Nucleotide Community Sequence Patterns

著者: Amnon Amir, Daniel McDonald, José A. Navas-Molina, Evguenia Kopylova, James T. Morton, Zhenjiang Zech Xu, Eric P. Kightley, Luke Thompson, Embriette R. Hyde, Antonio González, Rob Knight - mSystems 2017 被引用: 1,967

Deblur provides a rapid and sensitive means to assess ecological patterns driven by differentiation of closely related taxa. This algorithm provides a solution to the problem of identifying real ecological differences between taxa whose amplicons differ by a single base pair, is applicable in an automated fashion to large-scale sequencing data sets, and can integrate sequencing runs collected over time.