Identification of entacapone as a chemical inhibitor of FTO mediating metabolic regulation through FOXO1

著者: Shiming Peng, Wen Xiao, Dapeng Ju, Baofa Sun, Nannan Hou, Qianlan Liu, Yanli Wang, Haijiao Zhao, Chun‐Chun Gao, Song Zhang, Ran Cao, Pengfei Li, Huanwei Huang, Yongfen Ma, Yankai Wang, Weiyi Lai, Zhixiong Ma, Wei Zhang, Song Huang, Hailin Wang, Zhiyuan Zhang, Liping Zhao, Tao Cai, Yongliang Zhao, Fengchao Wang, Yongzhan Nie, Gang Zhi, Yun‐Gui Yang, Eric Erquan Zhang, Niu Huang - Science Translational Medicine 2019 被引用: 310

Entacapone improves metabolic homeostasis in diet-induced obese mice through a direct effect on an FTO-FOXO1 regulatory axis.