The shared susceptibility epitope of HLA-DR4 binds citrullinated self-antigens and the TCR

著者: Jia Jia Lim, Claerwen M. Jones, Tiing Jen Loh, Yi Tian Ting, Pirooz Zareie, Khai Lee Loh, Nathan Felix, Anish Suri, Murray McKinnon, Frederik Stevenaert, Ravi Sharma, Lars Klareskog, Vivianne Malmström, Daniel G. Baker, Anthony W. Purcell, Hugh H. Reid, Nicole L. La Gruta, Jamie Rossjohn - Science Immunology 2021 被引用: 41

Citrullination of a fibrinogen peptide influences HLA-DR4 binding and TCR usage by neoepitope-reactive T cells in rheumatoid arthritis.