Plasticity of Lgr5-Negative Cancer Cells Drives Metastasis in Colorectal Cancer

著者: Arianna Fumagalli, Koen C. Oost, Lennart Kester, Jessica Morgner, Laura Bornes, Lotte Bruens, Lisa Spaargaren, Maria Azkanaz, Tim Schelfhorst, Evelyne Beerling, Maria C. Heinz, Daniel Postrach, Daniëlle Seinstra, Anieta M. Sieuwerts, John W.M. Martens, Stefan van der Elst, Martijn v. Baalen, Debajit Bhowmick, Nienke Vrisekoop, Saskia I. J. Ellenbroek, Saskia J.E. Suijkerbuijk, Hugo J.G. Snippert, Jacco van Rheenen - Cell stem cell 2020 被引用: 309

cells, which display intrinsic capacity to become CSCs in a niche-independent manner and can restore epithelial hierarchies in metastatic tumors.