Nuclear MYH9-induced CTNNB1 transcription, targeted by staurosporin, promotes gastric cancer cell anoikis resistance and metastasis

著者: Gengtai Ye, Qingbin Yang, Xuetao Lei, Xianjun Zhu, Fengping Li, Jiayong He, Hao Chen, Ruoyu Ling, Haisheng Zhang, Tian Lin, Zhi-Ping Liang, Yanrui Liang, Haipeng Huang, Weihong Guo, Haijun Deng, Hao Liu, Yanfeng Hu, Jiang Yu, Guoxin Li - Theranostics 2020 被引用: 204

This study identified that nuclear MYH9-induced CTNNB1 expression promotes GC metastasis, which could be inhibited by staurosporine, indicating a novel therapy for GC peritoneal metastasis.