Near-infrared upconversion–activated CRISPR-Cas9 system: A remote-controlled gene editing platform

著者: Yongchun Pan, Jingjing Yang, Xiaowei Luan, Xinli Liu, Xueqing Li, Jian Yang, Ting Huang, Lu Sun, Yuzhen Wang, Youhui Lin, Yujun Song - Science Advances 2019 被引用: 270

), our strategies have successfully inhibited the proliferation of tumor cell via NIR light-activated gene editing both in vitro and in vivo. Overall, this exogenously controlled method presents enormous potential for targeted gene editing in deep tissues and treatment of a myriad of diseases.