Noncanonical inflammasome signaling elicits gasdermin D–dependent neutrophil extracellular traps

著者: Kaiwen Chen, Mercedes Monteleone, Dave Boucher, Gabriel Sollberger, Divya Ramnath, Nicholas D. Condon, Jessica B. von Pein, Petr Brož, Matthew J. Sweet, Kate Schroder - Science Immunology 2018 被引用: 618

mice. Our studies reveal that neutrophils use an inflammasome- and GSDMD-dependent mechanism to activate NETosis as a defense response against cytosolic bacteria.