Alexander Gusev
Active 1977–2026
- 145
- Papers
- 24,637
- Citations
- 58
- h-index
- 122
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Biochemistry, Genetics and Molecular Biology57.2%
- Medicine26.1%
- Neuroscience3.7%
- Computer Science3.5%
- Psychology2.3%
- Physics and Astronomy1.8%
- Other5.4%
Topics
- Genetic Associations and Epidemiology15.2%
- Genetic Mapping and Diversity in Plants and Animals4%
- Bioinformatics and Genomic Networks3.5%
- Epigenetics and DNA Methylation3.1%
- Genetic and phenotypic traits in livestock3%
- Genomics and Rare Diseases1.8%
- Other69.4%
Coauthors
- Bogdan Paşaniuc21
- Alkes L. Price19
- Hilary K. Finucane15
- Stefan Groha13
- Noah Zaitlen12
- Po‐Ru Loh12
- Yevgeniy R. Semenov12
- Benjamin M. Neale11
- Matthew L. Freedman11
- Kerry L. Reynolds10
- Nick Patterson10
- Nicholas Mancuso9
- Steven Gazal9
- Brendan Bulik‐Sullivan8
- Eliezer M. Van Allen8
- Gaurav Bhatia8
- Guihong Wan8
- Ji-Heui Seo8
- Sarah Abou Alaiwi8
- Shawn G. Kwatra8
- Amin H. Nassar7
- Elio Adib7
- Kun‐Hsing Yu7
- Leyre Zubiri7
All papers
- An atlas of genetic correlations across human diseases and traits
Authors: Brendan Bulik‐Sullivan, Hilary K. Finucane, Verneri Anttila, Alexander Gusev, Felix R. Day, Po‐Ru Loh, Laramie E. Duncan, John R. B. Perry, Nick Patterson, Elise Robinson, Mark J. Daly, Alkes L. Price, Benjamin M. Neale - Nature Genetics 2015 cited by 4,690
- Partitioning heritability by functional annotation using genome-wide association summary statistics
Authors: Hilary K. Finucane, Brendan Bulik‐Sullivan, Alexander Gusev, Gosia Trynka, Yakir Reshef, Po‐Ru Loh, Verneri Anttila, Han Xu, Chongzhi Zang, Kyle Kai-How Farh, Stephan Ripke, Felix R. Day, Shaun Purcell, Eli A. Stahl, Sara Lindström, John R. B. Perry, Yukinori Okada, Soumya Raychaudhuri, Mark J. Daly, Nick Patterson, Benjamin M. Neale, Alkes L. Price - Nature Genetics 2015 cited by 3,063
- Integrative approaches for large-scale transcriptome-wide association studies
Authors: Alexander Gusev, Arthur Ko, Huwenbo Shi, Gaurav Bhatia, Wonil Chung, Brenda W.J.H. Penninx, Rick Jansen, Eco J. C. de Geus, Dorret I. Boomsma, Fred A. Wright, Patrick F. Sullivan, Elina Nikkola, Marcus Alvarez, Mete Civelek, Aldons J. Lusis, Terho Lehtimäki, Emma Raitoharju, Mika Kähönen, Ilkka Seppälä, Olli T. Raitakari, Johanna Kuusisto, Markku Laakso, Alkes L. Price, Päivi Pajukanta, Bogdan Paşaniuc - Nature Genetics 2016 cited by 2,732
- Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores
Authors: Bjarni J. Vilhjálmsson, Jian Yang, Hilary K. Finucane, Alexander Gusev, Sara Lindström, Stephan Ripke, Giulio Genovese, Po‐Ru Loh, Gaurav Bhatia, Ron Do, Tristan J. Hayeck, Hong‐Hee Won, Sekar Kathiresan, Michele T. Pato, Carlos N. Pato, Rulla M. Tamimi, Eli A. Stahl, Noah Zaitlen, Bogdan Paşaniuc, Gillian M. Belbin, Eimear E. Kenny, Mikkel Heide Schierup, Philip L. De Jager, Nikolaos A. Patsopoulos, Steve McCarroll, Mark J. Daly, Shaun Purcell, Daniel I. Chasman, Benjamin M. Neale, Michael E. Goddard, Peter M. Visscher, Peter Kraft, Nick Patterson, Alkes L. Price, Stephan Ripke, Benjamin M. Neale, Aiden Corvin, James Walters, Kai-How Farh, Peter Holmans, Phil Lee, Brendan Bulik‐Sullivan, David Collier, Hailiang Huang, Tune H. Pers, Ingrid Agartz, Esben Agerbo, Margot Albus, Madeline Alexander, Farooq Amin, Silviu‐Alin Bacanu, Martin Begemann, Richard A. Belliveau, Judit Bene, Sarah E. Bergen, Elizabeth Bevilacqua, Tim B. Bigdeli, Donald W. Black, Richard Bruggeman, Nancy G. Buccola, Randy L. Buckner, William Byerley, Wiepke Cahn, Guiqing Cai, Dominique Campion, Rita M. Cantor, Vaughan J. Carr, Noa Carrera, Stanley V. Catts, Kimberly D. Chambert, Raymond Chan, Ronald Y.L. Chen, Eric Chen, Wei Cheng, Eric F.C. Cheung, Siow Ann Chong, C. Robert Cloninger, David Cohen, Nadine Cohen, Paul Cormican, Nick Craddock, James J. Crowley, David Curtis, Michael Davidson, Kenneth L. Davis, Franziska Degenhardt, Jurgen Del‐Favero, Lynn E. DeLisi, Ditte Demontis, Dimitris Dikeos, Timothy G. Dinan, Srdjan Djurovic, Gary Donohoe, Elodie Drapeau, Jubao Duan, Frank Dudbridge, Naser Durmishi, Peter Eichhammer, Johan G. Eriksson, Valentina Escott‐Price and 302 more - The American Journal of Human Genetics 2015 cited by 1,489
- Linkage disequilibrium–dependent architecture of human complex traits shows action of negative selection
Authors: Steven Gazal, Hilary K. Finucane, Nicholas A. Furlotte, Po‐Ru Loh, Pier Francesco Palamara, Xuanyao Liu, Armin Schoech, Brendan Bulik‐Sullivan, Benjamin M. Neale, Alexander Gusev, Alkes L. Price - Nature Genetics 2017 cited by 617
- Lung cancer in patients who have never smoked — an emerging disease
Authors: Jaclyn LoPiccolo, Alexander Gusev, David C. Christiani, Pasi A. Jänne - Nature Reviews Clinical Oncology 2024 cited by 249
- Probabilistic fine-mapping of transcriptome-wide association studies
Authors: Nicholas Mancuso, Malika Freund, Ruth Johnson, Huwenbo Shi, Gleb Kichaev, Alexander Gusev, Bogdan Paşaniuc - Nature Genetics 2019 cited by 444
- Machine learning for genetics-based classification and treatment response prediction in cancer of unknown primary
Authors: Intae Moon, Jaclyn LoPiccolo, Sylvan C. Baca, Lynette M. Sholl, Kenneth L. Kehl, Michael J. Hassett, David Liu, Deborah Schrag, Alexander Gusev - Nature Medicine 2023 cited by 112
- Prostate cancer reactivates developmental epigenomic programs during metastatic progression
Authors: Mark M. Pomerantz, Xintao Qiu, Yanyun Zhu, David Y. Takeda, Wenting Pan, Sylvan C. Baca, Alexander Gusev, Keegan Korthauer, Tesa Severson, Gavin Ha, Srinivas R. Viswanathan, Ji-Heui Seo, Holly M. Nguyen, Baohui Zhang, Bogdan Paşaniuc, Claudia Giambartolomei, Sarah Abou Alaiwi, Connor Bell, Edward O’Connor, Matthew Chabot, David R. Stillman, Rosina T. Lis, Alba Font‐Tello, Lewyn Li, Paloma Cejas, Andries M. Bergman, Joyce Sanders, Henk G. van der Poel, Simon A. Gayther, Kate Lawrenson, Marcos A. Fonseca, Jessica Reddy, Rosario I. Corona, Gleb Martovetsky, Brian Egan, Toni K. Choueiri, Leigh Ellis, Isla P. Garraway, Gwo‐Shu Mary Lee, Eva Corey, Henry W. Long, Wilbert Zwart, Matthew L. Freedman - Nature Genetics 2020 cited by 289
- Germline variants associated with toxicity to immune checkpoint blockade
Authors: Stefan Groha, Sarah Abou Alaiwi, Wenxin Xu, Vivek Naranbhai, Amin H. Nassar, Ziad Bakouny, Talal El Zarif, Renée Maria Saliby, Guihong Wan, Ahmad Rajeh, Elio Adib, Pier Vitale Nuzzo, Andrew Schmidt, Chris Labaki, Biagio Ricciuti, Joao V. Alessi, David A. Braun, Sachet A. Shukla, Tanya E. Keenan, Eliezer M. Van Allen, Mark M. Awad, Michael P. Manos, Osama E. Rahma, Leyre Zubiri, Alexandra–Chloé Villani, Benjamin P. Fairfax, Christian Hammer, Zia Khan, Kerry L. Reynolds, Yevgeniy R. Semenov, Deborah Schrag, Kenneth L. Kehl, Matthew L. Freedman, Toni K. Choueiri, Alexander Gusev - Nature Medicine 2022 cited by 107
- Scalable genetic screening for regulatory circuits using compressed Perturb-seq
Authors: Douglas Yao, Loïc Binan, Jon Bezney, Brooke Simonton, Jahanara Freedman, Chris J. Frangieh, Kushal K. Dey, Kathryn Geiger-Schuller, Basak Eraslan, Alexander Gusev, Aviv Regev, Brian Cleary - Nature Biotechnology 2023 cited by 103
- Partitioning Heritability of Regulatory and Cell-Type-Specific Variants across 11 Common Diseases
Authors: Alexander Gusev, Sang Lee, Gosia Trynka, Hilary K. Finucane, Bjarni J. Vilhjálmsson, Han Xu, Chongzhi Zang, Stephan Ripke, Brendan Bulik‐Sullivan, Eli A. Stahl, Anna K. Kähler, Christina M. Hultman, Shaun Purcell, Steven A. McCarroll, Mark J. Daly, Bogdan Paşaniuc, Patrick F. Sullivan, Benjamin M. Neale, Naomi R. Wray, Soumya Raychaudhuri, Alkes L. Price, Stephan Ripke, Benjamin M. Neale, Aiden Corvin, James Walters, Kai-How Farh, Peter Holmans, Phil Lee, Brendan Bulik‐Sullivan, David Collier, Hailiang Huang, Tune H. Pers, Ingrid Agartz, Esben Agerbo, Margot Albus, Madeline Alexander, Farooq Amin, Silviu‐Alin Bacanu, Martin Begemann, Richard A. Belliveau, Judit Bene, Sarah E. Bergen, Elizabeth Bevilacqua, Tim B. Bigdeli, Donald W. Black, Anders D. Børglum, Richard Bruggeman, Nancy G. Buccola, Randy L. Buckner, William Byerley, Wiepke Cahn, Guiqing Cai, Dominique Campion, Rita M. Cantor, Vaughan J. Carr, Noa Carrera, Stanley V. Catts, Kimberly D. Chambert, Raymond Chan, Ronald Y.L. Chen, Eric Chen, Wei Cheng, Eric Cheung, Siow Ann Chong, C. Robert Cloninger, David Cohen, Nadine Cohen, Paul Cormican, Nick Craddock, James J. Crowley, David Curtis, Michael H. Davidson, Kenneth L. Davis, Franziska Degenhardt, Jurgen Del‐Favero, Lynn E. DeLisi, Ditte Demontis, Dimitris Dikeos, Timothy G. Dinan, Srdjan Djurovic, Gary Donohoe, Elodie Drapeau, Jubao Duan, Frank Dudbridge, Naser Durmishi, Peter Eichhammer, Johan G. Eriksson, Valentina Escott‐Price, Laurent Essioux, Ayman H. Fanous, Martilias S. Farrell, Josef Frank, Lude Franke, Robert Freedman, Nelson B. Freimer, Marion Friedl, Joseph I. Friedman, Menachem Fromer, Giulio Genovese, Lyudmila Georgieva and 245 more - The American Journal of Human Genetics 2014 cited by 654
- Transcriptome-wide association study of schizophrenia and chromatin activity yields mechanistic disease insights
Authors: Alexander Gusev, Nicholas Mancuso, Hyejung Won, Maria Kousi, Hilary K. Finucane, Yakir Reshef, Lingyun Song, Alexias Safi, Steven A. McCarroll, Benjamin M. Neale, Roel A. Ophoff, Michael O’Donovan, Gregory E. Crawford, Daniel H. Geschwind, Nicholas Katsanis, Patrick F. Sullivan, Bogdan Paşaniuc, Alkes L. Price - Nature Genetics 2018 cited by 560
- Secure large-scale genome-wide association studies using homomorphic encryption
Authors: Marcelo Blatt, Alexander Gusev, Yuriy Polyakov, Shafi Goldwasser - National Academy of Sciences, IACR Cryptol. ePrint Arch. 2020 cited by 138
- Association of Cutaneous Immune-Related Adverse Events With Increased Survival in Patients Treated With Anti–Programmed Cell Death 1 and Anti–Programmed Cell Death Ligand 1 Therapy
Authors: Kimberly Tang, Jayhyun Seo, Bruce C. Tiu, Thomas K. Le, Vartan Pahalyants, Neel S. Raval, Pearl Ugwu‐Dike, Leyre Zubiri, Vivek Naranbhai, Mary Carrington, Alexander Gusev, Kerry L. Reynolds, Nicole R. LeBoeuf, Maryam M. Asgari, Shawn G. Kwatra, Yevgeniy R. Semenov - JAMA Dermatology 2022 cited by 130
- Contrasting genetic architectures of schizophrenia and other complex diseases using fast variance-components analysis
Authors: Po‐Ru Loh, Gaurav Bhatia, Alexander Gusev, Hilary K. Finucane, Brendan Bulik‐Sullivan, Samuela Pollack, Teresa R de Candia, Sang Lee, Naomi R. Wray, Kenneth S. Kendler, Michael O’Donovan, Benjamin M. Neale, Nick Patterson, Alkes L. Price - Nature Genetics 2015 cited by 532
- Ancestry-driven recalibration of tumor mutational burden and disparate clinical outcomes in response to immune checkpoint inhibitors
Authors: Amin H. Nassar, Elio Adib, Sarah Abou Alaiwi, Talal El Zarif, Stefan Groha, Elie W. Akl, Pier Vitale Nuzzo, Tarek H. Mouhieddine, Tomin Perea-Chamblee, Kodi Taraszka, Habib El‐Khoury, Muhieddine Labban, Christopher J. Fong, Kanika Arora, Chris Labaki, Wenxin Xu, Guru Sonpavde, Robert I. Haddad, Kent W. Mouw, Marios Giannakis, F. Stephen Hodi, Noah Zaitlen, Adam J. Schoenfeld, Nikolaus Schultz, Michael F. Berger, Laura E. MacConaill, Guruprasad Ananda, David J. Kwiatkowski, Toni K. Choueiri, Deborah Schrag, Jian Carrot‐Zhang, Alexander Gusev - Cancer Cell 2022 cited by 116
- CDKN2A Alterations and Response to Immunotherapy in Solid Tumors
Authors: Elio Adib, Amin H. Nassar, Elie W. Akl, Sarah Abou Alaiwi, Pier Vitale Nuzzo, Tarek H. Mouhieddine, Guru Sonpavde, Robert I. Haddad, Kent W. Mouw, Marios Giannakis, F. Stephen Hodi, Sachet A. Shukla, Alexander Gusev, David A. Braun, Toni K. Choueiri, David J. Kwiatkowski - Clinical Cancer Research 2021 cited by 129
- IL7 genetic variation and toxicity to immune checkpoint blockade in patients with melanoma
Authors: Chelsea Taylor, Robert Watson, Orion Tong, Weiyu Ye, Isar Nassiri, James J. Gilchrist, Alba Verge de los Aires, Piyush Kumar Sharma, Surya Koturan, Rosalin Cooper, Victoria K. Woodcock, Elsita Jungkurth, Brian Shine, Nicholas Coupe, Miranda Payne, David N. Church, Vivek Naranbhai, Stefan Groha, Paul Emery, Kulveer Mankia, Matthew L. Freedman, Toni K. Choueiri, Mark R. Middleton, Alexander Gusev, Benjamin P. Fairfax - Nature Medicine 2022 cited by 72
- Enzyme-mediated depletion of methylthioadenosine restores T cell function in MTAP-deficient tumors and reverses immunotherapy resistance
Authors: Donjeta Gjuka, Elio Adib, Kendra Garrison, Jianfeng Chen, Yuxue Zhang, Wenjiao Li, Daniel R. Boutz, Candice Lamb, Yuri Tanno, Amin H. Nassar, Talal El Zarif, Neil Kale, Mehrdad Rakaee, Tarek H. Mouhieddine, Sarah Abou Alaiwi, Alexander Gusev, Thomas E. Rogers, Jianjun Gao, George Georgiou, David J. Kwiatkowski, Everett Stone - Cancer Cell 2023 cited by 58
- Heritability enrichment of specifically expressed genes identifies disease-relevant tissues and cell types
Authors: Hilary K. Finucane, Yakir Reshef, Verneri Anttila, Kamil Slowikowski, Alexander Gusev, Andrea Byrnes, Steven Gazal, Po‐Ru Loh, Caleb A. Lareau, Noam Shoresh, Giulio Genovese, Arpiar Saunders, Evan Z. Macosko, Samuela Pollack, John R. B. Perry, Jason D. Buenrostro, B Bernstein, Soumya Raychaudhuri, Steven A. McCarroll, Benjamin M. Neale, Alkes L. Price - Nature Genetics 2017 cited by 1,220
- Integrating Gene Expression with Summary Association Statistics to Identify Genes Associated with 30 Complex Traits
Authors: Nicholas Mancuso, Huwenbo Shi, Pagé C. Goddard, Gleb Kichaev, Alexander Gusev, Bogdan Paşaniuc - The American Journal of Human Genetics 2017 cited by 334
- HLA-A*03 and response to immune checkpoint blockade in cancer: an epidemiological biomarker study
Authors: Vivek Naranbhai, Mathias Viard, Michael Dean, Stefan Groha, David A. Braun, Chris Labaki, Sachet A. Shukla, Yuko Yuki, Parantu K. Shah, Kevin M. Chin, Megan Wind‐Rotolo, Xinmeng Jasmine Mu, Paul B. Robbins, Alexander Gusev, Toni K. Choueiri, James L. Gulley, Mary Carrington - The Lancet Oncology 2021 cited by 126
- Artificial intelligence-aided clinical annotation of a large multi-cancer genomic dataset
Authors: Kenneth L. Kehl, Wenxin Xu, Alexander Gusev, Ziad Bakouny, Toni K. Choueiri, Irbaz Bin Riaz, Haitham Elmarakeby, Eliezer M. Van Allen, Deborah Schrag - Nature Communications 2021 cited by 54
