Andrew J. Brown
Active 1957–2025
- 137
- Papers
- 26,090
- Citations
- 88
- h-index
- 131
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Biochemistry, Genetics and Molecular Biology42.1%
- Medicine35.8%
- Immunology and Microbiology3.5%
- Nursing2.9%
- Neuroscience2.8%
- Computer Science2.6%
- Other10.3%
Topics
- Cholesterol and Lipid Metabolism4.7%
- Gut microbiota and health3.4%
- Lipid metabolism and biosynthesis2.4%
- Diet and metabolism studies2.3%
- Receptor Mechanisms and Signaling2.1%
- Cancer, Lipids, and Metabolism2.1%
- Other83%
Coauthors
- Laura J. Sharpe22
- Hongyuan Yang12
- Ximing Du12
- Wendy Jessup11
- Hudson W. Coates9
- Ingrid C. Gelissen9
- Jenny Wong8
- Roger T. Dean8
- Isabelle M. Capell-Hattam7
- Ngee Kiat Chua7
- Simon J. Dowell7
- Winnie Luu7
- Carmel M. Quinn6
- Eduardo Slatopolsky6
- Jane Finch6
- Carol Scott5
- Leonard Kritharides5
- Lydia Qian5
- Robert G. Parton5
- Anika V. Prabhu4
- Christine Bird4
- Cynthia S. Ritter4
- Guanghou Shui4
- J. P. Almeida4
All papers
- The Orphan G Protein-coupled Receptors GPR41 and GPR43 Are Activated by Propionate and Other Short Chain Carboxylic Acids
Authors: Andrew J. Brown, Susan M. Goldsworthy, Ashley Barnes, Michelle M. Eilert, Lili Tcheang, Dion A. Daniels, Alison I. Muir, Mark Wigglesworth, Ian J. Kinghorn, Neil J. Fraser, Nicholas B. Pike, Jay C. Strum, Klaudia Steplewski, Paul R. Murdock, Julie C. Holder, Fiona H. Marshall, Philip Szekeres, Shelagh Wilson, Diane M. Ignar, S.M. Foord, Alan Wise, Simon J. Dowell - Journal of Biological Chemistry 2003 cited by 2,345
- LMSD: LIPID MAPS structure database
Authors: Manish Sud, Eoin Fahy, David Cotter, Andrew J. Brown, Edward A. Dennis, Christopher K. Glass, Alfred H. Merrill, Robert C. Murphy, Christian R.H. Raetz, David W. Russell, Shankar Subramaniam - Nucleic Acids Research, Nucleic Acids Res. 2006 cited by 1,385
- Reducing safety-related drug attrition: the use of in vitro pharmacological profiling
Authors: Joanne Bowes, Andrew J. Brown, Jacques Hamon, Wolfgang Jarolimek, Arun Sridhar, Gareth Waldron, Steven Whitebread - Nature Reviews Drug Discovery 2012 cited by 743
- The Akt–SREBP nexus: cell signaling meets lipid metabolism
Authors: James R. Krycer, Laura J. Sharpe, Winnie Luu, Andrew J. Brown - Trends in Endocrinology and Metabolism 2010 cited by 363
- The DNA sequence of the human X chromosome
Authors: Mark T. Ross, Darren Grafham, Alison J. Coffey, Steven E. Scherer, Kirsten McLay, Donna M. Muzny, Matthias Platzer, Gareth R. Howell, Christine Burrows, Christine Bird, Adam Frankish, F.L. Lovell, Kevin Howe, Jennifer Ashurst, Robert S. Fulton, Ralf Sudbrak, Gaiping Wen, Matthew C. Jones, Matthew E. Hurles, T. Daniel Andrews, Carol Scott, Stephen M. J. Searle, Juliane Ramser, Adam Whittaker, Rebecca Deadman, Nigel P. Carter, Sarah Hunt, Rui Chen, Andrew Cree, Preethi H. Gunaratne, Paul Havlak, Anne V. Hodgson, Michael L. Metzker, Stephen Richards, Graham Scott, David L. Steffen, Erica Sodergren, David A. Wheeler, Kim C. Worley, R. Ainscough, K. D. Ambrose, M. Ali Ansari‐Lari, Swaroop Aradhya, R. I. S. Ashwell, Anne Babbage, C. L. Bagguley, Andrea Ballabio, Ruby Banerjee, Gary E. Barker, K. F. Barlow, Ian P. Barrett, Karen N. Bates, David Beare, Helen Beasley, O. Beasley, Alfred Beck, Graeme Bethel, Karin Blechschmidt, Nicola Brady, S. Bray-Allen, Anne Bridgeman, Andrew J. Brown, Mary Jean Brown, David Bonnin, Elspeth A. Bruford, Christian Buhay, Paula E. Burch, D. C. Burford, Joanne C. Burgess, W. Burrill, John H. Burton, Jackie Bye, C. Carder, Laura Carrel, Joseph Chako, J. C. Chapman, Dean Chavez, Ellson Chen, Guan Chen, Yuan Chen, Zhijian J. Chen, Craig Chinault, Alfredo Ciccodicola, S. Y. Clark, Graham Clarke, Chris M. Clee, S. M. Clegg, Kerstin P. Clerc-Blankenburg, Karen Clifford, V. Cobley, Charlotte G. Cole, Jen S. Conquer, N. Corby, Richard E. Connor, Robert David, J. Davies, Clay Davis, John N. Davis, Oliver Delgado, Denise R. Deshazo and 182 more - Nature 2005 cited by 1,166
- Reduction of Squalene Epoxidase by Cholesterol Accumulation Accelerates Colorectal Cancer Progression and Metastasis
Authors: Soo Young Jun, Andrew J. Brown, Ngee Kiat Chua, Ji‐Yong Yoon, Jeong-Ju Lee, Jin Ok Yang, Insu Jang, Su-Jin Jeon, Tae‐Ik Choi, Cheol‐Hee Kim, Nam-Soon Kim - Gastroenterology 2020 cited by 185
- Magnesium ion stimulation of bone marrow stromal cells enhances osteogenic activity, simulating the effect of magnesium alloy degradation
Authors: Sayuri Yoshizawa, Andrew J. Brown, Aaron Barchowsky, Charles Sfeir - Acta Biomaterialia 2014 cited by 574
- Controlling Cholesterol Synthesis beyond 3-Hydroxy-3-methylglutaryl-CoA Reductase (HMGCR)
Authors: Laura J. Sharpe, Andrew J. Brown - Journal of Biological Chemistry 2013 cited by 383
- Cholesterol-Dependent Degradation of Squalene Monooxygenase, a Control Point in Cholesterol Synthesis beyond HMG-CoA Reductase
Authors: Saloni Gill, Julian Stevenson, Ika Kristiana, Andrew J. Brown - Cell Metabolism 2011 cited by 307
- Fld1p, a functional homologue of human seipin, regulates the size of lipid droplets in yeast
Authors: Weihua Fei, Guanghou Shui, Bruno Gaëta, Ximing Du, Lars Kuerschner, Peng Li, Andrew J. Brown, Markus R. Wenk, Robert G. Parton, Hongyuan Yang - The Journal of Cell Biology 2008 cited by 473
- A structure of human Scap bound to Insig-2 suggests how their interaction is regulated by sterols
Authors: Renhong Yan, Pingping Cao, Wenqi Song, Hongwu Qian, Ximing Du, Hudson W. Coates, Xin Zhao, Yaning Li, Shuai Gao, Xin Gong, Ximing Liu, Jianhua Sui, Jianlin Lei, Hongyuan Yang, Andrew J. Brown, Qiang Zhou, Chuangye Yan, Nieng Yan - Science 2021 cited by 96
- Squalene monooxygenase: a journey to the heart of cholesterol synthesis
Authors: Ngee Kiat Chua, Hudson W. Coates, Andrew J. Brown - Progress in Lipid Research 2020 cited by 123
- ORP5 and ORP8 bind phosphatidylinositol-4, 5-biphosphate (PtdIns(4,5)P 2) and regulate its level at the plasma membrane
Authors: Rajesh Ghai, Ximing Du, Huan Wang, Jiangqing Dong, Charles Ferguson, Andrew J. Brown, Robert G. Parton, Jiawei Wu, Hongyuan Yang - Nature Communications 2017 cited by 206
- The E3 Ubiquitin Ligase MARCH6 Degrades Squalene Monooxygenase and Affects 3-Hydroxy-3-Methyl-Glutaryl Coenzyme A Reductase and the Cholesterol Synthesis Pathway
Authors: Noam Zelcer, Laura J. Sharpe, Anke Loregger, Ika Kristiana, Emma C. L. Cook, Lisa Phan, Julian Stevenson, Andrew J. Brown - Molecular and Cellular Biology 2014 cited by 177
- Oxysterols: Old Tale, New Twists
Authors: Winnie Luu, Laura J. Sharpe, Isabelle M. Capell-Hattam, Ingrid C. Gelissen, Andrew J. Brown - The Annual Review of Pharmacology and Toxicology 2016 cited by 145
- A role for oxysterol-binding protein–related protein 5 in endosomal cholesterol trafficking
Authors: Ximing Du, Jaspal Kaur Kumar, Charles Ferguson, Timothy A. Schulz, Yan Shan Ong, Wanjin Hong, William A. Prinz, Robert G. Parton, Andrew J. Brown, Hongyuan Yang - The Journal of Cell Biology 2011 cited by 316
- DHCR7: A vital enzyme switch between cholesterol and vitamin D production
Authors: Anika V. Prabhu, Winnie Luu, Dianfan Li, Laura J. Sharpe, Andrew J. Brown - Progress in Lipid Research 2016 cited by 201
- A Role for Phosphatidic Acid in the Formation of “Supersized” Lipid Droplets
Authors: Weihua Fei, Guanghou Shui, Yuxi Zhang, Natalie Krahmer, Charles Ferguson, Tamar S. Kapterian, Ruby C.Y. Lin, Ian W. Dawes, Andrew J. Brown, Peng Li, Xun Huang, Robert G. Parton, Markus R. Wenk, Tobias C. Walther, Hongyuan Yang - PLoS Genetics 2011 cited by 359
- Screening β-Arrestin Recruitment for the Identification of Natural Ligands for Orphan G-Protein–Coupled Receptors
Authors: C. Southern, Jennifer M. Cook, Zaynab Neetoo‐Isseljee, Debra L. Taylor, Catherine Kettleborough, Andy Merritt, Daniel L. Bassoni, William J. Raab, Elizabeth R. Quinn, Tom S. Wehrman, Anthony P. Davenport, Andrew J. Brown, Andrew R. Green, Mark Wigglesworth, Steve Rees - SLAS DISCOVERY 2013 cited by 181
- Cholesterol-mediated Degradation of 7-Dehydrocholesterol Reductase Switches the Balance from Cholesterol to Vitamin D Synthesis
Authors: Anika V. Prabhu, Winnie Luu, Laura J. Sharpe, Andrew J. Brown - Journal of Biological Chemistry 2016 cited by 155
- Desmosterol and DHCR24: Unexpected new directions for a terminal step in cholesterol synthesis
Authors: Eser J. Zerenturk, Laura J. Sharpe, Elina Ikonen, Andrew J. Brown - Progress in Lipid Research 2013 cited by 147
- Molecular Identification of High and Low Affinity Receptors for Nicotinic Acid
Authors: Alan Wise, Steven M. Foord, Neil J. Fraser, Ashley Barnes, Nabil A. Elshourbagy, Michelle M. Eilert, Diane M. Ignar, Paul R. Murdock, Klaudia Steplewski, Andrew R. Green, Andrew J. Brown, Simon J. Dowell, Philip Szekeres, David G. Hassall, Fiona H. Marshall, Shelagh Wilson, Nicholas B. Pike - Journal of Biological Chemistry 2003 cited by 541
- Allosteric enhancement of ORP1-mediated cholesterol transport by PI(4,5)P2/PI(3,4)P2
Authors: Jiangqing Dong, Ximing Du, Huan Wang, Jue Wang, Chang Lu, Xiang Chen, Zhiwen Zhu, Zhipu Luo, Li Yu, Andrew J. Brown, Hongyuan Yang, Jiawei Wu - Nature Communications 2019 cited by 97
- Pretreatment blood–brain barrier disruption and post-endovascular intracranial hemorrhage
Authors: Richard Leigh, Sören Christensen, Bruce Campbell, Michael P. Marks, Gregory W. Albers, Maarten G. Lansberg, For the DEFUSE 2 Investigators, DEFUSE 2 Investigators, Jeffery Saver, Pierre Fayad, George Howard, Thomas A. Tomsick, Tudor G. Jovin, Lawrence R. Wechsler, Sharon DeCesare, Gregory W. Albers, Maarten G. Lansberg, Stephanie Kemp, Dung Thai, Michael J Wilder, A Tricot, Amelia Sherr, Helmi L. Lutsep, Logan McDaneld, Darren Larsen, Todd Czartoski, Bart P. Keogh, Amer Malik, Andrew J. Brown, Richard A. Bernstein, Kathryn Muskovich, Cherylee W. J. Chang, Tracy Stern, Steven Warach, Lisa Davis, Franz Fazekas, Thomas Seifert‐Held, Gregory W. Albers, Greg Zaharchuk, Michael P. Marks, Aaryani Tipirneni‐Sajja, Michael Mlynash - Neurology 2016 cited by 83
