Aylwin Ng
Active 1974–2022
- 39
- Papers
- 17,995
- Citations
- 38
- h-index
- 39
- i10-index
Citations
Citation sources
Countries
Institutions
- Harvard University1.2%
- Radboud University Nijmegen0.8%
- Radboud University Medical Center0.8%
- Inserm0.7%
- Massachusetts General Hospital0.6%
- University of Bonn0.5%
- Other95.4%
Fields
- Biochemistry, Genetics and Molecular Biology39.4%
- Medicine32.5%
- Immunology and Microbiology20.4%
- Neuroscience2.5%
- Agricultural and Biological Sciences1.5%
- Nursing1.3%
- Other2.4%
Topics
- Gut microbiota and health6.9%
- Autophagy in Disease and Therapy4.4%
- Immune responses and vaccinations3.7%
- Immune cells in cancer3.1%
- Immune Response and Inflammation1.9%
- Cell death mechanisms and regulation1.8%
- Other78.2%
Coauthors
- Ramnik J. Xavier28
- Mihai G. Netea7
- Cisca Wijmenga6
- Leo A. B. Joosten6
- Vinod Kumar6
- Shih‐Chin Cheng5
- Frank L. van de Veerdonk4
- J.W.M. van der Meer4
- Marije Oosting4
- Bart Jan Kullberg3
- Jason M. Eisenberg3
- Jessica Quintin3
- Junying Yuan3
- Mark J. Daly3
- Sanne P. Smeekens3
- Stephen J. Elledge3
- Abraham L. Brass2
- Adrian T. Ting2
- Ali Aghajanirefah2
- Anna Latiano2
- Beth Levine2
- Borisas Bursteinas2
- Bénédicte F. Py2
- Colin Logie2
All papers
- mTOR- and HIF-1α–mediated aerobic glycolysis as metabolic basis for trained immunity
Authors: Shih‐Chin Cheng, Jessica Quintin, Robert A. Cramer, Kelly M. Shepardson, Sadia Saeed, Vinod Kumar, Evangelos J. Giamarellos‐Bourboulis, Joost H.A. Martens, Nagesha Rao, Ali Aghajanirefah, Ganesh R. Manjeri, Li Yang, Daniela C. Ifrim, Rob J.W. Arts, Brian M. J. W. van der Veer, Peter M.T. Deen, Colin Logie, Luke O'neill, Peter H.G.M. Willems, Frank L. van de Veerdonk, J.W.M. van der Meer, Aylwin Ng, Leo A. B. Joosten, Cisca Wijmenga, Hendrik G. Stunnenberg, Ramnik J. Xavier, Mihai G. Netea - Science 2014 cited by 2,224
- Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43
Authors: Kendle M. Maslowski, Angélica T. Vieira, Aylwin Ng, Jan Kranich, Frédéric Sierro, Di Yu, Heidi Schilter, Michael S. Rolph, Fabienne Mackay, David Artis, Ramnik J. Xavier, Mauro Martins Teixeira, Charles R. Mackay - Nature 2009 cited by 3,244
- Epigenetic programming of monocyte-to-macrophage differentiation and trained innate immunity
Authors: Sadia Saeed, Jessica Quintin, Hindrik H. D. Kerstens, Nagesha Rao, Ali Aghajanirefah, Filomena Matarese, Shih‐Chin Cheng, Jacqueline M. Ratter, Kim Berentsen, Martijn A. van der Ent, Nilofar Sharifi, Eva M. Janssen‐Megens, Menno ter Huurne, Amit Mandoli, Tom van Schaik, Aylwin Ng, Frances Burden, Kate Downes, Mattia Frontini, Vinod Kumar, Evangelos J. Giamarellos‐Bourboulis, Willem H. Ouwehand, J.W.M. van der Meer, Leo A. B. Joosten, Cisca Wijmenga, Joost H.A. Martens, Ramnik J. Xavier, Colin Logie, Mihai G. Netea, Hendrik G. Stunnenberg - Science 2014 cited by 1,768
- Genome-wide analysis reveals mechanisms modulating autophagy in normal brain aging and in Alzheimer's disease
Authors: Marta M. Lipinski, Bin Zheng, Tao Lu, Zhenyu Yan, Bénédicte F. Py, Aylwin Ng, Ramnik J. Xavier, Cheng Li, Bruce A. Yankner, Clemens R. Scherzer, Junying Yuan - National Academy of Sciences, Proceedings of the National Academy of Sciences 2010 cited by 663
- GABARAP sequesters the FLCN-FNIP tumor suppressor complex to couple autophagy with lysosomal biogenesis
Authors: Jonathan M. Goodwin, Ward G. Walkup, Kirsty M. Hooper, Taoyingnan Li, Chieko Kishi‐Itakura, Aylwin Ng, Timothy Z. Lehmberg, Archana Jha, Sravya Kommineni, Katherine Fletcher, Jorge García‐Fortanet, Yaya Fan, Qing Tang, Menghao Wei, Asmita Agrawal, Sagar R. Budhe, Sreekanth R. Rouduri, Dan Baird, Jeff Saunders, Janna Kiselar, Mark R. Chance, Andrea Ballabio, B.A. Appleton, John H. Brumell, Oliver Florey, Leon O. Murphy - Science Advances 2021 cited by 126
- Reovirus infection triggers inflammatory responses to dietary antigens and development of celiac disease
Authors: Romain Bouziat, Reinhard Hinterleitner, Judy J. Brown, Jennifer Stencel-Baerenwald, Mine R. Ikizler, Toufic Mayassi, Marlies Meisel, Sangman M. Kim, Valentina Discepolo, Andrea J. Pruijssers, Jordan D. Ernest, Jason A. Iskarpatyoti, L M M Costes, Ian Lawrence, Brad A. Palanski, Mukund Varma, Matthew A. Zurenski, Solomiia Khomandiak, Nicole McAllister, Pavithra Aravamudhan, Karl W. Boehme, Fengling Hu, Janneke N. Samsom, Hans-Christian Reinecker, Sonia S. Kupfer, Stefano Guandalini, Carol E. Semrad, Valérie Abadie, Chaitan Khosla, Luis B. Barreiro, Ramnik J. Xavier, Aylwin Ng, Terence S. Dermody, Bana Jabrì - Science 2017 cited by 453
- Caspase 8 inhibits programmed necrosis by processing CYLD
Authors: Marie Anne O’Donnell, Eva Pérez-Jiménez, Andrew Oberst, Aylwin Ng, Ramin Massoumi, Ramnik J. Xavier, Douglas R. Green, Adrian T. Ting - Nature Cell Biology 2011 cited by 487
- Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47
Authors: Carl A. Anderson, Gabrielle Boucher, Charlie W. Lees, André Franke, Mauro D’Amato, Kent D. Taylor, James Lee, Philippe Goyette, Marcin Imieliński, Anna Latiano, Caroline Lagacé, Regan Scott, Leila Amininejad, Suzannah Bumpstead, Leonard Baidoo, Robert N. Baldassano, Murray L. Barclay, Theodore M. Bayless, Stephan Brand, Carsten Büning, Jean‐Frédéric Colombel, Lee A. Denson, Martine De Vos, Marla C. Dubinsky, Cathryn Edwards, David Ellinghaus, Rudolf S.N. Fehrmann, James Floyd, Timothy H. Florin, Denis Franchimont, Lude Franke, Michel Georges, Jürgen Glas, Nicole L. Glazer, Stephen L. Guthery, Talin Haritunians, Nicholas K. Hayward, Jean‐Pierre Hugot, Gilles Jobin, Debby Laukens, Ian C. Lawrance, Marc Lémann, Arie Levine, Cécile Libioulle, Édouard Louis, Dermot McGovern, Mónica Milla, Grant W. Montgomery, Katherine I. Morley, Craig Mowat, Aylwin Ng, William G. Newman, Roel A. Ophoff, Laura Papi, Orazio Palmieri, Laurent Peyrin‐Biroulet, Julián Panés, Anne Phillips, Natalie J. Prescott, Deborah D. Proctor, Rebecca Roberts, Richard K. Russell, Paul Rutgeerts, Jeremy Sanderson, Miquel Sans, L. Philip Schumm, Frank Seibold, Yashoda Sharma, Lisa A. Simms, Mark Seielstad, A. Hillary Steinhart, Stephan R. Targan, Leonard H. van den Berg, Morten Vatn, Hein W. Verspaget, Thomas D. Walters, Cisca Wijmenga, David C. Wilson, Harm-Jan Westra, Ramnik J. Xavier, Zhen Zhao, Cyriel Y. Ponsioen, Vibeke Andersen, Leif Törkvist, Maria Gazouli, Nicholas P. Anagnou, Tom H. Karlsen, Limas Kupčinskas, Jurgita Šventoraitytė, John Mansfield, Subra Kugathasan, Mark S. Silverberg, Jonas Halfvarson, Jerome I. Rotter, Christopher G. Mathew, Anne M. Griffiths, Richard B. Gearry, Tariq Ahmad, Steven R. Brant, Mathias Chamaillard and 13 more - Nature Genetics 2011 cited by 1,353
- Virus-Plus-Susceptibility Gene Interaction Determines Crohn's Disease Gene Atg16L1 Phenotypes in Intestine
Authors: Ken Cadwell, Khushbu Patel, Nicole S. Maloney, Ta‐Chiang Liu, Aylwin Ng, Chad Storer, Richard D. Head, Ramnik J. Xavier, Thaddeus S. Stappenbeck, Herbert W. Virgin - Cell 2010 cited by 903
- Autophagy Controls BCG-Induced Trained Immunity and the Response to Intravesical BCG Therapy for Bladder Cancer
Authors: Kathrin Buffen, Marije Oosting, Jessica Quintin, Aylwin Ng, Johanneke Kleinnijenhuis, Vinod Kumar, Esther van de Vosse, Cisca Wijmenga, Reinout van Crevel, Egbert Oosterwijk, Anne J. Grotenhuis, Sita H. Vermeulen, Lambertus A. Kiemeney, Frank L. van de Veerdonk, Georgios Chamilos, Ramnik J. Xavier, J.W.M. van der Meer, Mihai G. Netea, Leo A. B. Joosten - PLoS Pathogens 2014 cited by 225
- Identification of a Molecular Signaling Network that Regulates a Cellular Necrotic Cell Death Pathway
Authors: Junichi Hitomi, Dana E. Christofferson, Aylwin Ng, Jianhua Yao, Alexei Degterev, Ramnik J. Xavier, Junying Yuan - Cell 2008 cited by 983
- Image-based genome-wide siRNA screen identifies selective autophagy factors
Authors: Anthony Orvedahl, Rhea Sumpter, Guanghua Xiao, Aylwin Ng, Zhongju Zou, Yi Tang, Masahiro Narimatsu, Christopher J. Gilpin, Qihua Sun, Michael G. Roth, Christian V. Forst, Jeffrey L. Wrana, Ying E. Zhang, Katherine Luby‐Phelps, Ramnik J. Xavier, Yang Xie, Beth Levine - Nature 2011 cited by 480
- Leucine-rich repeat (LRR) proteins: Integrators of pattern recognition and signaling in immunity
Authors: Aylwin Ng, Ramnik J. Xavier - Autophagy 2011 cited by 257
- Chitinase 3-like 1 induces survival and proliferation of intestinal epithelial cells during chronic inflammation and colitis-associated cancer by regulating S100A9
Authors: Daren Low, Renuka Subramaniam, Lin Li, Tomoki Aomatsu, Atsushi Mizoguchi, Aylwin Ng, Arianna K. DeGruttola, Chun Geun Lee, Jack A. Elias, Akira Andoh, Mari Mino–Kenudson, Emiko Mizoguchi - Oncotarget 2015 cited by 95
- Murine Norovirus Infection Induces TH1 Inflammatory Responses to Dietary Antigens
Authors: Romain Bouziat, Scott B. Biering, Elaine Kouame, Kishan Sangani, Soowon Kang, Jordan D. Ernest, Mukund Varma, Judy J. Brown, Kelly Urbanek, Terence S. Dermody, Aylwin Ng, Reinhard Hinterleitner, Seungmin Hwang, Bana Jabrì - Cell Host & Microbe 2018 cited by 87
- RNA interference screen for human genes associated with West Nile virus infection
Authors: Manoj N. Krishnan, Aylwin Ng, Bindu Sukumaran, Felicia D. Gilfoy, Pradeep D. Uchil, Hameeda Sultana, Abraham L. Brass, Rachel Adametz, Melody Tsui, Feng Qian, Ruth R. Montgomery, Sima Lev, Peter W. Mason, Raymond A. Koski, Stephen J. Elledge, Ramnik J. Xavier, Hervé Agaisse, Erol Fikrig - Nature 2008 cited by 518
- Functional genomics identifies type I interferon pathway as central for host defense against Candida albicans
Authors: Sanne P. Smeekens, Aylwin Ng, Vinod Kumar, Melissa D. Johnson, Theo S. Plantinga, Cleo C. van Diemen, Peer Arts, Eugène T.P. Verwiel, Mark S. Gresnigt, Karin Fransén, Suzanne van Sommeren, Marije Oosting, Shih‐Chin Cheng, Leo A. B. Joosten, Alexander Hoischen, Bart Jan Kullberg, William K. Scott, John R. Perfect, J.W.M. van der Meer, Cisca Wijmenga, Mihai G. Netea, Ramnik J. Xavier - Nature Communications 2013 cited by 217
- Functional CRISPR screening identifies the ufmylation pathway as a regulator of SQSTM1/p62
Authors: Rowena DeJesus, Francesca Moretti, Gregory McAllister, Zuncai Wang, Phil Bergman, Shanming Liu, Elizabeth Frias, John Alford, John Reece-Hoyes, Alicia Lindeman, Jennifer Kelliher, Carsten Russ, Judith Knehr, Walter Carbone, Martin Beibel, Guglielmo Roma, Aylwin Ng, John A. Tallarico, Jeffery A. Porter, Ramnik J. Xavier, Craig Mickanin, Leon O. Murphy, Gregory R. Hoffman, Beat Nyfeler - eLife 2016 cited by 156
- Ubiquitin Ligase TRIM62 Regulates CARD9-Mediated Anti-fungal Immunity and Intestinal Inflammation
Authors: Zhifang Cao, Kara L. Conway, Robert J. W. Heath, Jason S. Rush, Elizaveta S. Leshchiner, Zaida G. Ramirez‐Ortiz, Natalia B. Nedelsky, Hailiang Huang, Aylwin Ng, Agnès Gardet, Shih‐Chin Cheng, Alykhan F. Shamji, John D. Rioux, Cisca Wijmenga, Mihai G. Netea, Terry K. Means, Mark J. Daly, Ramnik J. Xavier - Immunity 2015 cited by 135
- Autophagy is essential for cardiac morphogenesis during vertebrate development
Authors: Eunmyong Lee, Yeon Koo, Aylwin Ng, Yongjie Wei, Kate Luby-Phelps, Amy L. Juraszek, Ramnik J. Xavier, Ondine Cleaver, Beth Levine, James F. Amatruda - Autophagy 2014 cited by 140
- Wnt signaling regulates mitochondrial physiology and insulin sensitivity
Authors: John C. Yoon, Aylwin Ng, Brian H Kim, Antônio C. Bianco, Ramnik J. Xavier, Stephen J. Elledge - Genes & Development 2010 cited by 254
- The RIG-I-like helicase receptor MDA5 (IFIH1) is involved in the host defense against Candida infections
Authors: Martin Jaeger, Robin van der Lee, Shih‐Chin Cheng, Melissa D. Johnson, Vinod Kumar, Aylwin Ng, Theo S. Plantinga, Sanne P. Smeekens, Marije Oosting, X. Wang, Winfried Barchet, Katherine A. Fitzgerald, Leo A. B. Joosten, John R. Perfect, Cisca Wijmenga, Frank L. van de Veerdonk, Martijn A. Huynen, Ramnik J. Xavier, Bart Jan Kullberg, Mihai G. Netea - European Journal of Clinical Microbiology & Infectious Diseases 2015 cited by 86
- Identifying Relationships among Genomic Disease Regions: Predicting Genes at Pathogenic SNP Associations and Rare Deletions
Authors: Soumya Raychaudhuri, Robert M. Plenge, Elizabeth J. Rossin, Aylwin Ng, Shaun Purcell, Pamela Sklar, Edward M. Scolnick, Ramnik J. Xavier, David Altshuler, Mark J. Daly - PLoS Genetics 2009 cited by 430
- A Genome-Wide siRNA Screen Reveals Multiple mTORC1 Independent Signaling Pathways Regulating Autophagy under Normal Nutritional Conditions
Authors: Marta M. Lipinski, Greg Hoffman, Aylwin Ng, Wen Zhou, Bénédicte F. Py, Emily Hsu, Xuxin Liu, Jason M. Eisenberg, Jun S. Liu, John Blenis, Ramnik J. Xavier, Junying Yuan - Developmental Cell 2010 cited by 221
