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Brian Keith

Active 1983–2026

75
Papers
18,941
Citations
51
h-index
59
i10-index

Citations

Citations per year for Brian Keith1983: 2 citations1984: 4 citations1985: 8 citations1986: 10 citations1987: 15 citations1988: 13 citations1989: 22 citations1990: 16 citations1991: 20 citations1992: 17 citations1993: 13 citations1994: 9 citations1995: 19 citations1996: 19 citations1997: 11 citations1998: 12 citations1999: 12 citations2000: 11 citations2001: 16 citations2002: 14 citations2003: 23 citations2004: 43 citations2005: 55 citations2006: 92 citations2007: 120 citations2008: 177 citations2009: 219 citations2010: 252 citations2011: 218 citations2012: 239 citations2013: 272 citations2014: 227 citations2015: 249 citations2016: 238 citations2017: 289 citations2018: 337 citations2019: 805 citations2020: 936 citations2021: 912 citations2022: 751 citations2023: 558 citations2024: 805 citations2025: 472 citations2026: 21 citations

Citation sources

Countries

World map of the countries and regions citing this authorUnited States: 2,900 citing papers, 30.9% of this breakdownChina: 1,636 citing papers, 17.4% of this breakdownUnited Kingdom: 552 citing papers, 5.9% of this breakdownGermany: 478 citing papers, 5.1% of this breakdownItaly: 305 citing papers, 3.2% of this breakdownFrance: 266 citing papers, 2.8% of this breakdownCanada: 264 citing papers, 2.8% of this breakdownJapan: 261 citing papers, 2.8% of this breakdownSpain: 221 citing papers, 2.4% of this breakdownSwitzerland: 185 citing papers, 2% of this breakdownIndia: 155 citing papers, 1.6% of this breakdownSouth Korea: 154 citing papers, 1.6% of this breakdown
0%30.9%Other 21.5%

Institutions

Fields

  • Biochemistry, Genetics and Molecular Biology49.8%
  • Medicine37.8%
  • Immunology and Microbiology4.6%
  • Agricultural and Biological Sciences2.6%
  • Engineering1.7%
  • Neuroscience1.1%
  • Other2.4%

Topics

  • Cancer, Hypoxia, and Metabolism11.6%
  • CAR-T cell therapy research6.4%
  • Immune Cell Function and Interaction2.6%
  • Epigenetics and DNA Methylation2.5%
  • Virus-based gene therapy research2%
  • RNA modifications and cancer2%
  • Other72.9%

Coauthors

All papers

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  1. Distinct Signaling of Coreceptors Regulates Specific Metabolism Pathways and Impacts Memory Development in CAR T Cells

    Authors: Omkar U. Kawalekar, Roddy S. O’Connor, Joseph A. Fraietta, Lili Guo, Shannon E. McGettigan, Avery D. Posey, Prachi Patel, Sònia Guedan, John Scholler, Brian Keith, Nathaniel W. Snyder, Ian A. Blair, Michael C. Milone, Carl H. June - Immunity 2016 cited by 1,205

  2. HIF1α and HIF2α: sibling rivalry in hypoxic tumour growth and progression

    Authors: Brian Keith, Randall S. Johnson, M. Celeste Simon - Nature reviews. Cancer 2011 cited by 1,664

  3. Augmentation of Antitumor Immunity by Human and Mouse CAR T Cells Secreting IL-18

    Authors: Biliang Hu, Jiangtao Ren, Yanping Luo, Brian Keith, Regina M. Young, John Scholler, Yangbing Zhao, Carl H. June - Cell Reports 2017 cited by 494

  4. Enhancing CAR T cell persistence through ICOS and 4-1BB costimulation

    Authors: Sònia Guedan, Avery D. Posey, Carolyn E. Shaw, Anna Wing, Tong Da, Prachi Patel, Shannon E. McGettigan, Victoria Casado‐Medrano, Omkar U. Kawalekar, Mireia Uribe‐Herranz, Decheng Song, J. Joseph Melenhorst, Simon F. Lacey, John Scholler, Brian Keith, Regina M. Young, Carl H. June - JCI Insight 2018 cited by 580

  5. Differential Roles of Hypoxia-Inducible Factor 1α (HIF-1α) and HIF-2α in Hypoxic Gene Regulation

    Authors: Cheng‐Jun Hu, Li-Yi Wang, Lewis A. Chodosh, Brian Keith, M. Celeste Simon - Molecular and Cellular Biology 2003 cited by 1,386

  6. Engineered CAR T Cells Targeting the Cancer-Associated Tn-Glycoform of the Membrane Mucin MUC1 Control Adenocarcinoma

    Authors: Avery D. Posey, Robert D. Schwab, Alina C. Boesteanu, Catharina Steentoft, Ulla Mandel, Boris Engels, Jennifer D. Stone, Thomas D. Madsen, Karin Schreiber, Kathleen M. Haines, Alexandria P. Cogdill, Taylor J Chen, Decheng Song, John Scholler, David M. Kranz, Michael D. Feldman, Regina M. Young, Brian Keith, Hans Schreiber, Henrik Clausen, Laura A. Johnson, Carl H. June - Immunity 2016 cited by 586

  7. HIF2α-Dependent Lipid Storage Promotes Endoplasmic Reticulum Homeostasis in Clear-Cell Renal Cell Carcinoma

    Authors: Bo Qiu, Daniel Ackerman, Danielle J. Sanchez, Bo Li, Joshua D. Ochocki, Alison Grazioli, Ekaterina Bobrovnikova-Marjon, J. Alan Diehl, Brian Keith, M. Celeste Simon - Cancer Discovery 2015 cited by 407

  8. FBP1 loss disrupts liver metabolism and promotes tumorigenesis through a hepatic stellate cell senescence secretome

    Authors: Fuming Li, Peiwei Huangyang, Michelle Burrows, Kathy Guo, Romain Riscal, Jason T. Godfrey, Kyoung Eun Lee, Nan Lin, Pearl Lee, Ian A. Blair, Brian Keith, Bo Li, M. Celeste Simon - Nature Cell Biology 2020 cited by 204

  9. Hypoxia-Inducible Factors, Stem Cells, and Cancer

    Authors: Brian Keith, M. Celeste Simon - Cell 2007 cited by 1,202

  10. Oxygen availability and metabolic adaptations

    Authors: Michael S. Nakazawa, Brian Keith, M. Celeste Simon - Nature reviews. Cancer 2016 cited by 445

  11. Pancreatic cancer therapy with combined mesothelin-redirected chimeric antigen receptor T cells and cytokine-armed oncolytic adenoviruses

    Authors: Keisuke Watanabe, Yanping Luo, Tong Da, Sònia Guedan, Marco Ruella, John Scholler, Brian Keith, Regina M. Young, Boris Engels, Suvi Sorsa, Mikko Siurala, Riikka Havunen, Siri Tähtinen, Akseli Hemminki, Carl H. June - JCI Insight 2018 cited by 280

  12. Fructose-1,6-bisphosphatase opposes renal carcinoma progression

    Authors: Bo Li, Bo Qiu, David S.M. Lee, Zandra E. Walton, Joshua D. Ochocki, Lijoy K. Mathew, Anthony Mancuso, T. Gade, Brian Keith, Itzhak Nissim, M. Celeste Simon - Nature 2014 cited by 540

  13. Blocking methionine catabolism induces senescence and confers vulnerability to GSK3 inhibition in liver cancer

    Authors: Fuming Li, Pingyu Liu, Mi Wen, Liucheng Li, Nicole Anderson, Nicholas P. Lesner, Michelle Burrows, Jacqueline B. Plesset, Ariana D. Majer, Guanlin Wang, Jinyang Li, Lingzhi Zhu, Brian Keith, M. Celeste Simon - Nature Cancer 2024 cited by 75

  14. The role of oxygen availability in embryonic development and stem cell function

    Authors: M. Celeste Simon, Brian Keith - Nature Reviews Molecular Cell Biology 2008 cited by 971

  15. Cholesterol Auxotrophy as a Targetable Vulnerability in Clear Cell Renal Cell Carcinoma

    Authors: Romain Riscal, Caroline J. Bull, Clementina Mesaros, Jennifer M. Finan, Madeleine Carens, Elaine S. Ho, Jimmy P. Xu, Jason Godfrey, Paul Brennan, Mattias Johansson, Mark P. Purdue, Stephen J. Chanock, Daniela Mariosa, Nicholas J. Timpson, Emma E. Vincent, Brian Keith, Ian A. Blair, Nicolas Skuli, M. Celeste Simon - Cancer Discovery 2021 cited by 123

  16. HIF-2α, but not HIF-1α, promotes iron absorption in mice

    Authors: Maria Mastrogiannaki, Pavle Matak, Brian Keith, M. Celeste Simon, Sophie Vaulont, Carole Peyssonnaux - Journal of Clinical Investigation 2009 cited by 494

  17. Hypoxia-inducible factor 2α regulates macrophage function in mouse models of acute and tumor inflammation

    Authors: Hongxia Z. Imtiyaz, Emily Williams, Michele M. Hickey, Shetal Patel, Amy C. Durham, Lijun Yuan, Rachel Hammond, Phyllis A. Gimotty, Brian Keith, M. Celeste Simon - Journal of Clinical Investigation 2010 cited by 450

  18. Distinct Signaling of Coreceptors Regulates Specific Metabolism Pathways and Impacts Memory Development in CAR T Cells

    Authors: Omkar U. Kawalekar, Roddy S. O’ Connor, Joseph A. Fraietta, Lili Guo, Shannon E. McGettigan, Avery D. Posey, Prachi Patel, Sònia Guedan, John Scholler, Brian Keith, Nathaniel W. Snyder, Ian A. Blair, Michael C. Milone, Carl H. June - Immunity 2016 cited by 192

  19. Acute postnatal ablation of Hif-2 α results in anemia

    Authors: Michaela Gruber, Cheng‐Jun Hu, Randall S. Johnson, Eric J. Brown, Brian Keith, M. Celeste Simon - National Academy of Sciences, Proceedings of the National Academy of Sciences 2007 cited by 466

  20. Dysregulated mTORC1 renders cells critically dependent on desaturated lipids for survival under tumor-like stress

    Authors: Regina M. Young, Daniel Ackerman, Zachary L. Quinn, Anthony Mancuso, Michaela Gruber, Liping Liu, Dionysios N. Giannoukos, Ekaterina Bobrovnikova-Marjon, J. Alan Diehl, Brian Keith, M. Celeste Simon - Genes & Development 2013 cited by 214

  21. IRE1α RNase–dependent lipid homeostasis promotes survival in Myc-transformed cancers

    Authors: Hong Xie, Chih-Hang Anthony Tang, Jun Song, Anthony Mancuso, Juan R. Del Valle, Jin Cao, Yan Xiang, Chi V. Dang, Roy Lan, Danielle J. Sanchez, Brian Keith, Chih‐Chi Andrew Hu, M. Celeste Simon - Journal of Clinical Investigation 2018 cited by 135

  22. Hypoxia-inducible factor–2 (HIF-2) regulates hepatic erythropoietin in vivo

    Authors: Erinn B. Rankin, Mangatt P. Biju, Qingdu Liu, Travis L. Unger, Jennifer Rha, Randall S. Johnson, M. Celeste Simon, Brian Keith, Volker H. Haase - Journal of Clinical Investigation 2007 cited by 587

  23. Hypoxia-Induced Energy Stress Regulates mRNA Translation and Cell Growth

    Authors: Liping Liu, Timothy P. Cash, Russell G. Jones, Brian Keith, Craig B. Thompson, M. Celeste Simon - Molecular Cell 2006 cited by 609

  24. Arginase 2 Suppresses Renal Carcinoma Progression via Biosynthetic Cofactor Pyridoxal Phosphate Depletion and Increased Polyamine Toxicity

    Authors: Joshua D. Ochocki, Sanika Khare, Markus Heß, Daniel Ackerman, Bo Qiu, Jennie I. Daisak, Andrew J. Worth, Nan Lin, Pearl Lee, Hong Xie, Bo Li, Bradley Wubbenhorst, Tobi G. Maguire, Katherine L. Nathanson, James C. Alwine, Ian A. Blair, Itzhak Nissim, Brian Keith, M. Celeste Simon - Cell Metabolism 2018 cited by 135