Michael C. Milone
Active 1998–2025
- 70
- Papers
- 22,487
- Citations
- 54
- h-index
- 68
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Medicine72%
- Biochemistry, Genetics and Molecular Biology14.1%
- Immunology and Microbiology10.4%
- Engineering1.7%
- Materials Science0.4%
- Neuroscience0.4%
- Other1%
Topics
- CAR-T cell therapy research21.3%
- Immune Cell Function and Interaction7.3%
- Virus-based gene therapy research6.2%
- Immunotherapy and Immune Responses6%
- Nanowire Synthesis and Applications4.3%
- Viral Infectious Diseases and Gene Expression in Insects3.5%
- Other51.4%
Coauthors
- Carl H. June30
- Roddy S. O’Connor18
- Selene Nuñez-Cruz14
- Joseph A. Fraietta12
- Simon F. Lacey12
- Bruce L. Levine11
- J. Joseph Melenhorst11
- Alfred L. Garfall10
- Vijay Bhoj9
- Adam D. Cohen8
- Edward A. Stadtmauer7
- James L. Riley7
- John Scholler7
- Megan M. Davis7
- Saba Ghassemi7
- Wei‐Ting Hwang7
- Dan T. Vogl6
- Don L. Siegel6
- John Leferovich6
- Stephan A. Grupp6
- Stephen J. Schuster6
- David M. Barrett5
- Nathaniel W. Snyder5
- Omkar U. Kawalekar5
All papers
- CAR T cell immunotherapy for human cancer
Authors: Carl H. June, Roddy S. O’Connor, Omkar U. Kawalekar, Saba Ghassemi, Michael C. Milone - Science 2018 cited by 3,210
- Chimeric Antigen Receptor–Modified T Cells for Acute Lymphoid Leukemia
Authors: Stephan A. Grupp, Michael Kalos, David M. Barrett, Richard Aplenc, David L. Porter, Susan R. Rheingold, David T. Teachey, Anne Chew, Bernd Hauck, J. Fraser Wright, Michael C. Milone, Bruce L. Levine, Carl H. June - New England Journal of Medicine 2013 cited by 3,491
- Distinct Signaling of Coreceptors Regulates Specific Metabolism Pathways and Impacts Memory Development in CAR T Cells
Authors: Omkar U. Kawalekar, Roddy S. O’Connor, Joseph A. Fraietta, Lili Guo, Shannon E. McGettigan, Avery D. Posey, Prachi Patel, Sònia Guedan, John Scholler, Brian Keith, Nathaniel W. Snyder, Ian A. Blair, Michael C. Milone, Carl H. June - Immunity 2016 cited by 1,205
- Chimeric antigen receptor T cells persist and induce sustained remissions in relapsed refractory chronic lymphocytic leukemia
Authors: David Porter, Wei‐Ting Hwang, Noelle V. Frey, Simon F. Lacey, Pamela A. Shaw, Alison W. Loren, Adam Bagg, Katherine T. Marcucci, Angela Shen, Vanessa Gonzalez, David E Ambrose, Stephan A. Grupp, Anne Chew, Zhaohui Zheng, Michael C. Milone, Bruce L. Levine, J. Joseph Melenhorst, Carl H. June - Science Translational Medicine 2015 cited by 1,727
- Clinical use of lentiviral vectors
Authors: Michael C. Milone, Una O’Doherty - Leukemia 2018 cited by 893
- Reengineering chimeric antigen receptor T cells for targeted therapy of autoimmune disease
Authors: Christoph T. Ellebrecht, Vijay Bhoj, Arben Nace, Eun Jung Choi, Xuming Mao, Michael Jeffrey Cho, Giovanni Di Zenzo, Antonio Lanzavecchia, John T. Seykora, George Cotsarelis, Michael C. Milone, Aimee Payne - Science 2016 cited by 727
- B cell maturation antigen–specific CAR T cells are clinically active in multiple myeloma
Authors: Adam D. Cohen, Alfred L. Garfall, Edward A. Stadtmauer, J. Joseph Melenhorst, Simon F. Lacey, Eric Lancaster, Dan T. Vogl, Brendan M. Weiss, Karen Dengel, Annemarie Nelson, Gabriela Plesa, Fang Chen, Megan M. Davis, Wei‐Ting Hwang, Regina M. Young, Jennifer L. Brogdon, Randi Isaacs, Iulian Pruteanu-Malinici, Don L. Siegel, Bruce L. Levine, Carl H. June, Michael C. Milone - Journal of Clinical Investigation 2019 cited by 790
- Rapid manufacturing of non-activated potent CAR T cells
Authors: Saba Ghassemi, Joseph S. Durgin, Selene Nuñez-Cruz, Jai Patel, John Leferovich, Marilia Rita Pinzone, Feng Shen, Katherine D. Cummins, Gabriela Plesa, Vito Adrian Cantu, Shantan Reddy, Frederic D. Bushman, Saar Gill, Una O’Doherty, Roddy S. O’Connor, Michael C. Milone - Nature Biomedical Engineering 2022 cited by 280
- An introduction to chimeric antigen receptor (CAR) T‐cell immunotherapy for human cancer
Authors: Steven Feins, Weimin Kong, Erik F. Williams, Michael C. Milone, Joseph A. Fraietta - American Journal of Hematology 2019 cited by 615
- Precision targeting of autoantigen-specific B cells in muscle-specific tyrosine kinase myasthenia gravis with chimeric autoantibody receptor T cells
Authors: Sangwook Oh, Xuming Mao, Sílvio M. Vieira, Jinmin Lee, Darshil Patel, Eun Jung Choi, Andrea Alvarado, Ebony Cottman‐Thomas, Damián Maseda, Patricia Tsao, Christoph T. Ellebrecht, Sami Khella, David P. Richman, Kevin C. O’Connor, Uri Herzberg, Gwendolyn K. Binder, Michael C. Milone, Samik Basu, Aimee Payne - Nature Biotechnology 2023 cited by 170
- Chimeric Receptors Containing CD137 Signal Transduction Domains Mediate Enhanced Survival of T Cells and Increased Antileukemic Efficacy In Vivo
Authors: Michael C. Milone, Jonathan D. Fish, Carmine Carpenito, Richard G. Carroll, Gwendolyn K. Binder, David T. Teachey, Minu Samanta, Mehdi Lakhal, Brian Gloss, Gwenn Danet-Desnoyers, Dario Campana, James L. Riley, Stephan A. Grupp, Carl H. June - Molecular Therapy 2009 cited by 1,189
- Reducing Ex Vivo Culture Improves the Antileukemic Activity of Chimeric Antigen Receptor (CAR) T Cells
Authors: Saba Ghassemi, Selene Nuñez-Cruz, Roddy S. O’Connor, Joseph A. Fraietta, Prachi Patel, John Scholler, David M. Barrett, Stefan Lundh, Megan M. Davis, Felipe Bedoya, Changfeng Zhang, John Leferovich, Simon F. Lacey, Bruce L. Levine, Stephan A. Grupp, Carl H. June, J. Joseph Melenhorst, Michael C. Milone - Cancer Immunology Research 2018 cited by 302
- Substrate Rigidity Regulates Human T Cell Activation and Proliferation
Authors: Roddy S. O’Connor, Xueli Hao, K. Robert Shen, Keenan T. Bashour, Tatiana Akimova, Wayne W. Hancock, Lance C. Kam, Michael C. Milone - The Journal of Immunology 2012 cited by 323
- T-cell phenotypes associated with effective CAR T-cell therapy in postinduction vs relapsed multiple myeloma
Authors: Alfred L. Garfall, Ehren K. Dancy, Adam D. Cohen, Wei‐Ting Hwang, Joseph A. Fraietta, Megan M. Davis, Bruce L. Levine, Don L. Siegel, Edward A. Stadtmauer, Dan T. Vogl, Adam Waxman, Aaron P. Rapoport, Michael C. Milone, Carl H. June, J. Joseph Melenhorst - Blood Advances 2019 cited by 229
- Antigen-specific B cell depletion for precision therapy of mucosal pemphigus vulgaris
Authors: Jinmin Lee, Daniel K. Lundgren, Xuming Mao, Sílvio M. Vieira, Selene Nuñez-Cruz, Erik F. Williams, Charles‐Antoine Assenmacher, Enrico Radaelli, Sangwook Oh, Baomei Wang, Christoph T. Ellebrecht, Joseph A. Fraietta, Michael C. Milone, Aimee Payne - Journal of Clinical Investigation 2020 cited by 155
- Persistence of long-lived plasma cells and humoral immunity in individuals responding to CD19-directed CAR T-cell therapy
Authors: Vijay Bhoj, Dimitrios C. Arhontoulis, Gerald Wertheim, James Capobianchi, Colleen Callahan, Christoph T. Ellebrecht, Amrom E. Obstfeld, Simon F. Lacey, J. Joseph Melenhorst, Farzana Nazimuddin, Wei‐Ting Hwang, Shannon L. Maude, Mariusz A. Wasik, Adam Bagg, Stephen J. Schuster, Michael D. Feldman, David L. Porter, Stephen Grupp, Carl H. June, Michael C. Milone - Blood 2016 cited by 271
- High-Affinity GD2-Specific CAR T Cells Induce Fatal Encephalitis in a Preclinical Neuroblastoma Model
Authors: Sarah A. Richman, Selene Nuñez-Cruz, Babak Moghimi, Lucy Z. Li, Zachary T. Gershenson, Zissimos P. Mourelatos, David M. Barrett, Stephan A. Grupp, Michael C. Milone - Cancer Immunology Research 2017 cited by 268
- Engineering-enhanced CAR T cells for improved cancer therapy
Authors: Michael C. Milone, Jie Xu, Sai‐Juan Chen, McKensie Collins, Jianfeng Zhou, Daniel J. Powell, J. Joseph Melenhorst - Nature Cancer 2021 cited by 134
- 4-1BB costimulation promotes CAR T cell survival through noncanonical NF-κB signaling
Authors: Benjamin Philipson, Roddy S. O’Connor, Michael J. May, Carl H. June, Steven Μ. Albelda, Michael C. Milone - Science Signaling 2020 cited by 213
- Control of large, established tumor xenografts with genetically retargeted human T cells containing CD28 and CD137 domains
Authors: Carmine Carpenito, Michael C. Milone, Raffit Hassan, Jacqueline C. Simonet, Mehdi Lakhal, Megan M. Suhoski, Angel Varela‐Rohena, Kathleen M. Haines, Daniel F. Heitjan, Steven Μ. Albelda, Richard G. Carroll, James L. Riley, Ira Pastan, Carl H. June - National Academy of Sciences, Proceedings of the National Academy of Sciences 2009 cited by 889
- A human orthogonal IL-2 and IL-2Rβ system enhances CAR T cell expansion and antitumor activity in a murine model of leukemia
Authors: Qian Zhang, Morgan Hresko, Lora K. Picton, Leon Su, Michael J. Hollander, Selene Nuñez-Cruz, Zheng Zhang, Charles‐Antoine Assenmacher, Jonathan T. Sockolosky, K. Christopher García, Michael C. Milone - Science Translational Medicine 2021 cited by 142
- Changes in Bone Marrow Tumor and Immune Cells Correlate with Durability of Remissions Following BCMA CAR T Therapy in Myeloma
Authors: Kavita M. Dhodapkar, Adam D. Cohen, Akhilesh Kaushal, Alfred L. Garfall, Renee Julia Manalo, Allison R. Carr, Samuel S. McCachren, Edward A. Stadtmauer, Simon F. Lacey, J. Joseph Melenhorst, Carl H. June, Michael C. Milone, Madhav V. Dhodapkar - Blood Cancer Discovery 2022 cited by 108
- Targeted inhibition of tumor-specific glutaminase diminishes cell-autonomous tumorigenesis
Authors: Yan Xiang, Zachary E. Stine, Jinsong Xia, Yunqi Lu, Roddy S. O’Connor, Brian J. Altman, Annie L. Hsieh, Arvin M. Gouw, Ajit G. Thomas, Ping Gao, Linchong Sun, Libing Song, Benedict Yan, Barbara S. Slusher, Jingli Zhuo, London Lucien Ooi, Caroline Lee, Anthony Mancuso, Andrew S. McCallion, Anne Le, Michael C. Milone, Stephen Rayport, Dean W. Felsher, Chi V. Dang - Journal of Clinical Investigation 2015 cited by 397
- Identification of Chimeric Antigen Receptors That Mediate Constitutive or Inducible Proliferation of T Cells
Authors: Matthew J. Frigault, Ji‐Hyun Lee, Maria C. Basil, Carmine Carpenito, Shinichiro Motohashi, John Scholler, Omkar U. Kawalekar, Sònia Guedan, Shannon E. McGettigan, Avery D. Posey, Sonny Ang, Laurence J.N. Cooper, Jesse M. Platt, F. Brad Johnson, Chrystal M. Paulos, Yangbing Zhao, Michael Kalos, Michael C. Milone, Carl H. June - Cancer Immunology Research 2015 cited by 331
