Brian T. Chait
Active 1985–2025
- Also published as
- Brian T Chait
- 209
- Papers
- 63,905
- Citations
- 123
- h-index
- 202
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Biochemistry, Genetics and Molecular Biology47.5%
- Medicine22.8%
- Neuroscience9.3%
- Chemistry7.9%
- Immunology and Microbiology5.2%
- Agricultural and Biological Sciences3.1%
- Other4.2%
Topics
- Ion channel regulation and function3.7%
- Genomics and Chromatin Dynamics3.1%
- RNA Research and Splicing3%
- Regulation of Appetite and Obesity2.5%
- Mass Spectrometry Techniques and Applications2.5%
- RNA and protein synthesis mechanisms2.2%
- Other83%
Coauthors
- Michael P. Rout53
- Andrej Šali21
- Paul Dominic B. Olinares21
- Kelly R. Molloy19
- Wenzhu Zhang19
- David Fenyö16
- John D. Aitchison15
- Rosemary Williams13
- Seth A. Darst13
- Robert G. Roeder12
- Steven L. Cohen12
- Yi Shi12
- Andrew N. Krutchinsky11
- Elizabeth A. Campbell11
- Javier Fernández-Martı́nez10
- Roderick MacKinnon10
- Ronald C. Beavis10
- Alan J. Tackett9
- Ileana M. Cristea9
- Junjie Wang9
- Yingming Zhao9
- James Chen8
- Martine Cadène8
- Peter C. Fridy8
All papers
- The Structure of the Potassium Channel: Molecular Basis of K + Conduction and Selectivity
Authors: D. Doyle, João H. Morais‐Cabral, Richard A. Pfuetzner, Anling Kuo, Jacqueline M. Gulbis, Steven L. Cohen, Brian T. Chait, Roderick MacKinnon - Science 1998 cited by 6,857
- A robust pipeline for rapid production of versatile nanobody repertoires
Authors: Peter C. Fridy, Yinyin Li, Sarah Keegan, Mary Kay Thompson, Ilona Nudelman, Johannes F. Scheid, Marlene Oeffinger, Michel C. Nussenzweig, David Fenyö, Brian T. Chait, Michael P. Rout - Nature Methods 2014 cited by 535
- Genome-wide gene expression tuning reveals diverse vulnerabilities of M. tuberculosis
Authors: Barbara Bosch, Michael A. DeJesus, Nicholas C. Poulton, Wenzhu Zhang, Curtis A. Engelhart, Anisha Zaveri, Sophie Lavalette, Nadine Ruecker, Carolina Trujillo, Joshua B. Wallach, Shuqi Li, Sabine Ehrt, Brian T. Chait, Dirk Schnappinger, Jeremy M. Rock - Cell 2021 cited by 355
- Sequence and Structural Convergence of Broad and Potent HIV Antibodies That Mimic CD4 Binding
Authors: Johannes F. Scheid, Hugo Mouquet, Beatrix Ueberheide, Ron Diskin, Florian Klein, Thiago Y. Oliveira, John Pietzsch, David Fenyö, Alexander Abadir, Klara Velinzon, Arlene Hurley, Sunnie Myung, Farid Boulad, Pascal Poignard, Dennis R. Burton, Florencia Pereyra, David D. Ho, Bruce D. Walker, Michael S. Seaman, Pamela J. Björkman, Brian T. Chait, Michel C. Nussenzweig - Science 2011 cited by 1,192
- Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1–phosphatidylinositol-3-kinase complex
Authors: Yun Zhong, Qing Jun Wang, Xianting Li, Ying Yan, Jonathan Backer, Brian T. Chait, Nathaniel Heintz, Zhenyu Yue - Nature Cell Biology 2009 cited by 970
- Weight-Reducing Effects of the Plasma Protein Encoded by the obese Gene
Authors: Jeffrey L. Halaas, K.S. Gajiwala, Margherita Maffei, Steven L. Cohen, Brian T. Chait, Daniel Rabinowitz, Roger L. Lallone, S.K. Burley, Jeffrey M. Friedman - Science 1995 cited by 4,459
- Integrative Structure And Functional Anatomy Of A Nuclear Pore Complex
Authors: Seung Joong Kim, Javier Fernández-Martı́nez, Ilona Nudelman, Yi Shi, Wenzhu Zhang, Barak Raveh, Thurston Herricks, Brian D. Slaughter, Joanna A. Hogan, Paula Upla, Ilan E. Chemmama, Riccardo Pellarin, Ignacia Echeverria, Manjunatha Shivaraju, Azraa S. Chaudhury, Junjie Wang, Rosemary Williams, Jay R. Unruh, Charles H. Greenberg, Erica Y. Jacobs, Zhiheng Yu, M. Jason de la Cruz, Roxana Mironska, David L. Stokes, John D. Aitchison, Martin F. Jarrold, Jennifer L. Gerton, Steven J. Ludtke, Christopher W. Akey, Brian T. Chait, Andrej Šali, Michael P. Rout - Nature 2018 cited by 548
- Nuclear ARP2/3 drives DNA break clustering for homology-directed repair
Authors: Benjamin R. Schrank, Tomás Aparicio, Yinyin Li, Wakam Chang, Brian T. Chait, Gregg G. Gundersen, Max E. Gottesman, Jean Gautier - Nature 2018 cited by 422
- Comprehensive structure and functional adaptations of the yeast nuclear pore complex
Authors: Christopher W. Akey, Digvijay Singh, Christna Ouch, Ignacia Echeverria, Ilona Nudelman, Joseph M. Varberg, Zulin Yu, Fei Fang, Yi Shi, Junjie Wang, Daniel J. Salzberg, Kangkang Song, Xu Chen, James C. Gumbart, Sergey Suslov, Jay R. Unruh, Sue L. Jaspersen, Brian T. Chait, Andrej Šali, Javier Fernández-Martı́nez, Steven J. Ludtke, Elizabeth Villa, Michael P. Rout - Cell 2022 cited by 191
- A PHD finger of NURF couples histone H3 lysine 4 trimethylation with chromatin remodelling
Authors: Joanna Wysocka, Tomek Swigut, Hua Xiao, Thomas A. Milne, So Yeon Kwon, Joe Landry, Monika Kauer, Alan J. Tackett, Brian T. Chait, Paul Badenhorst, Carl Wu, C. David Allis - Nature 2006 cited by 1,184
- The molecular architecture of the nuclear basket
Authors: Digvijay Singh, Neelesh Soni, Joshua Hutchings, Ignacia Echeverria, Farhaz Shaikh, Madeleine Duquette, Sergey Suslov, Zhixun Li, Trevor van Eeuwen, Kelly R. Molloy, Yi Shi, Junjie Wang, Qiang Guo, Brian T. Chait, Javier Fernández-Martı́nez, Michael P. Rout, Andrej Săli, Elizabeth Villa - Cell 2024 cited by 83
- Dynamic regulation of TFH selection during the germinal centre reaction
Authors: Julia Merkenschlager, Shlomo Finkin, Víctor Ramos, Julian Kraft, Melissa Cipolla, Carla R. Nowosad, Harald Hartweger, Wenzhu Zhang, Paul Dominic B. Olinares, Anna Gazumyan, Thiago Y. Oliveira, Brian T. Chait, Michel C. Nussenzweig - Nature 2021 cited by 112
- Ultrasensitive Detection of Circulating LINE-1 ORF1p as a Specific Multicancer Biomarker
Authors: Martin S. Taylor, Connie Wu, Peter C. Fridy, Stephanie J. Zhang, Yasmeen Senussi, Justina C. Wolters, Tatiana Cajuso, Wen‐Chih Cheng, John D. Heaps, Bryant D. Miller, Kei Mori, Limor Cohen, Hua Jiang, Kelly R. Molloy, Brian T. Chait, Michael Goggins, Irun Bhan, Joseph W. Franses, Xiaoyu Yang, Mary‐Ellen Taplin, Xinan Wang, David C. Christiani, Bruce E. Johnson, Matthew Meyerson, Ravindra Uppaluri, Ann Marie Egloff, Elyssa N. Denault, Laura M. Spring, Tian‐Li Wang, Ie‐Ming Shih, Jennifer E. Fairman, Euihye Jung, Kshitij S. Arora, Osman H. Yilmaz, Sonia Cohen, Tatyana Sharova, Gary Chi, Bryanna L. Norden, Yuhui Song, Linda T. Nieman, Leontios Pappas, Aparna R. Parikh, Matthew R. Strickland, Ryan B. Corcoran, Tomas Mustelin, George Eng, Ömer H. Yilmaz, Ursula A. Matulonis, Andrew T. Chan, Steven J. Skates, Bo R. Rueda, Ronny Drapkin, Samuel J. Klempner, Vikram Deshpande, David T. Ting, Michael P. Rout, John LaCava, David R. Walt, Kathleen H. Burns - Cancer Discovery 2023 cited by 85
- X-ray structure of a ClC chloride channel at 3.0 Å reveals the molecular basis of anion selectivity
Authors: Raimund Dutzler, Ernest B. Campbell, Martine Cadène, Brian T. Chait, Roderick MacKinnon - Nature 2002 cited by 1,617
- The molecular architecture of the nuclear pore complex
Authors: Frank Alber, Svetlana Dokudovskaya, Liesbeth M. Veenhoff, Wenzhu Zhang, Julia Kipper, Damien P. Devos, Adisetyantari Suprapto, Orit Karni-Schmidt, Rosemary Williams, Brian T. Chait, Andrej Šali, Michael P. Rout - Nature 2007 cited by 1,082
- Affinity Proteomics Reveals Human Host Factors Implicated in Discrete Stages of LINE-1 Retrotransposition
Authors: Martin S. Taylor, John LaCava, Paolo Mita, Kelly R. Molloy, Cheng Ran Lisa Huang, Donghui Li, Emily M. Adney, Hua Jiang, Kathleen H. Burns, Brian T. Chait, Michael P. Rout, Jef D. Boeke, Lixin Dai - Cell 2013 cited by 259
- The Yeast Nuclear Pore Complex
Authors: Michael P. Rout, John D. Aitchison, Adisetyantari Suprapto, Kelly Hjertaas, Yingming Zhao, Brian T. Chait - The Journal of Cell Biology 2000 cited by 1,405
- Asymmetric Molecular Architecture of the Human γ-Tubulin Ring Complex
Authors: Michał W. Wieczorek, L. Urnavicius, Shih-Chieh Ti, Kelly R. Molloy, Brian T. Chait, Tarun M. Kapoor - Cell 2019 cited by 154
- Essential role for autophagy protein Atg7 in the maintenance of axonal homeostasis and the prevention of axonal degeneration
Authors: Masaaki Komatsu, Qing Jun Wang, Gay R. Holstein, Victor L. Friedrich, Junichi Iwata, Eiki Kominami, Brian T. Chait, Keiji Tanaka, Zhenyu Yue - National Academy of Sciences, Proceedings of the National Academy of Sciences 2007 cited by 612
- Structural basis for backtracking by the SARS-CoV-2 replication–transcription complex
Authors: Brandon Malone, James Chen, Qi Wang, Eliza Llewellyn, Young Joo Choi, Paul Dominic B. Olinares, Xinyun Cao, Carolina Hernández, Edward T. Eng, Brian T. Chait, David E. Shaw, Robert Landick, Seth A. Darst, Elizabeth A. Campbell - National Academy of Sciences, Proceedings of the National Academy of Sciences 2021 cited by 125
- ABI5 acts downstream of ABI3 to execute an ABA‐dependent growth arrest during germination
Authors: Luis Lopez‐Molina, Sébastien Mongrand, Derek T. McLachlin, Brian T. Chait, Nam‐Hai Chua - The Plant Journal 2002 cited by 683
- Structural basis for substrate selection by the SARS-CoV-2 replicase
Authors: Brandon Malone, Jason K. Perry, Paul Dominic B. Olinares, Hery W. Lee, James Chen, T.C. Appleby, Joy Y. Feng, John P. Bilello, Honkit Ng, J Sotiris, Mark Ebrahim, Eugene Chua, Joshua H. Mendez, Edward T. Eng, Robert Landick, Matthias Götte, Brian T. Chait, Elizabeth A. Campbell, Seth A. Darst - Nature 2023 cited by 85
- Highly synergistic combinations of nanobodies that target SARS-CoV-2 and are resistant to escape
Authors: Fred D. Mast, Peter C. Fridy, Natalia E. Ketaren, Junjie Wang, Erica Y. Jacobs, Jean Paul Olivier, Tanmoy Sanyal, Kelly R. Molloy, Fabian Schmidt, Magdalena Rutkowska, Yiska Weisblum, Lucille M. Rich, Elizabeth R. Vanderwall, Nicholas Dambrauskas, Vladimir Vigdorovich, Sarah Keegan, Jacob B. Jiler, Milana E. Stein, Paul Dominic B. Olinares, Louis Herlands, Théodora Hatziioannou, D. Noah Sather, Jason S. Debley, David Fenyö, Andrej Šali, Paul D. Bieniasz, John D. Aitchison, Brian T. Chait, Michael P. Rout - eLife 2021 cited by 71
- Dissecting the Structural Dynamics of the Nuclear Pore Complex
Authors: Zhanna Hakhverdyan, Kelly R. Molloy, Sarah Keegan, Thurston Herricks, Dante Lepore, Mary Munson, Roman I. Subbotin, David Fenyö, John D. Aitchison, Javier Fernández-Martı́nez, Brian T. Chait, Michael P. Rout - Molecular Cell 2020 cited by 60
