Bruce J. Brew
Active 1988–2025
- 156
- Papers
- 25,014
- Citations
- 91
- h-index
- 152
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Medicine40.9%
- Neuroscience24.6%
- Immunology and Microbiology23.3%
- Biochemistry, Genetics and Molecular Biology7.1%
- Psychology0.7%
- Computer Science0.6%
- Other2.8%
Topics
- HIV Research and Treatment8.3%
- Tryptophan and brain disorders7.8%
- Alzheimer's disease research and treatments5.8%
- Neuroinflammation and Neurodegeneration Mechanisms5.3%
- Dementia and Cognitive Impairment Research4%
- Stress Responses and Cortisol3.4%
- Other65.4%
Coauthors
- Gilles J. Guillemin40
- Lucette A. Cysique33
- Richard W. Price18
- Joga Chaganti11
- Paola Cinque11
- Chai K. Lim10
- George A. Smythe9
- Lars Hagberg9
- Gregory J. Dore8
- Magnus Gisslén8
- Stephen J. Kerr8
- Anthony Byrne7
- Patricia J. Armati7
- Paul Maruff7
- Thomas M. Gates7
- Anthony D. Kelleher6
- D.R. Darley6
- Gayathri Sundaram6
- Htein Linn Aung6
- Justin C. McArthur6
- Louise Pemberton6
- Melissa J. Churchill6
- Sharon R. Lewin6
- Andrew Carr5
All papers
- Donanemab in Early Symptomatic Alzheimer Disease
Authors: John R. Sims, Jennifer A. Zimmer, Cynthia Evans, Ming‐Chi Lu, Paul Ardayfio, JonDavid Sparks, Alette M. Wessels, Sergey Shcherbinin, Hong Wang, Emel Serap Monkul Nery, Emily C. Collins, Paul R. Solomon, Stephen Salloway, Liana G. Apostolova, Oskar Hansson, Craig Ritchie, Dawn A. Brooks, Mark A. Mintun, Daniel Skovronsky, TRAILBLAZER-ALZ 2 Investigators, Rafael Abreu, Pinky Agarwal, Puja Aggarwal, Marc Agronin, Alison Allen, Dario Altamirano, Gustavo Alva, James Andersen, Allan Anderson, Donald D. Anderson, Jennifer Arnold, Takashi Asada, Yasuhiro Aso, Vikram Atit, Ricardo Ayala, Michael Badruddoja, Hanna Badzio-jagiello, Michal Bajaček, Dávid Barton, David G. Bear, Sabrina Benjamin, Richard Bergeron, Perminder Bhatia, Sandra E. Black, Allan Block, Mohammad Reza Bolouri, Wendy Bond, Jean Bouthillier, Sharon A. Brangman, Bruce J. Brew, Sarah Brisbin, Toby Brisken, Amy Brodtmann, Mark Brody, Jared R. Brosch, Celia Brown, Paul Brownstone, Sylwia Bukowczan, Jeffrey M. Burns, A Cabrera, Horace Capote, Ángel Carrasco, José Yépez, Eric Chavez, Howard Chertkow, Urszula Chyrchel-Paszkiewicz, Anthony Ciabarra, Edward Clemmons, Daniel M. Cohen, Robert M. Cohen, Ian J. Cohen, Mauricio Concha, Brian Costell, Denis Crimmins, Yvette Cruz-pagan, Adolfo Cueli, Robert Cupelo, Maciej Czarnecki, David Darby, P. L. J. Dautzenberg, Peter Paul De Deyn, Jose De La Gandara, Kenneth Deck, David DiBenedetto, Mark DiBuono, Eric Dinnerstein, Ahmet Dirican, Shanker Dixit, Jacek Dobryniewski, Ryan Drake, Peter Drysdale, Ranjan Duara, John P. Duffy, Aaron Ellenbogen, Victor Faradji, Marc Feinberg, Robert Feldman, Simon Fishman, Stephen Flitman, Concetta Forchetti and 209 more - JAMA 2023 cited by 2,562
- Recent evidence for an expanded role of the kynurenine pathway of tryptophan metabolism in neurological diseases
Authors: Michael D. Lovelace, Bianca Varney, Gayathri Sundaram, Matthew J. Lennon, Chai K. Lim, Kelly R. Jacobs, Gilles J. Guillemin, Bruce J. Brew - Neuropharmacology 2016 cited by 381
- Validity of the CogState Brief Battery: Relationship to Standardized Tests and Sensitivity to Cognitive Impairment in Mild Traumatic Brain Injury, Schizophrenia, and AIDS Dementia Complex
Authors: Paul Maruff, Elizabeth Thomas, Lucette A. Cysique, Bruce J. Brew, Alex Collie, Peter J. Snyder, Robert H. Pietrzak - Archives of Clinical Neuropsychology 2009 cited by 639
- Expression of indoleamine 2,3‐dioxygenase and production of quinolinic acid by human microglia, astrocytes, and neurons
Authors: Gilles J. Guillemin, George A. Smythe, Osamu Takikawa, Bruce J. Brew - Glia 2004 cited by 482
- Deferiprone in Alzheimer Disease
Authors: Scott Ayton, Dávid Barton, Bruce J. Brew, Amy Brodtmann, Roger Clarnette, Patricia Desmond, David Devos, Kathryn A. Ellis, Amir Fazlollahi, Caroline Fradette, Anita Goh, Paweł Kalinowski, Christopher Kyndt, Rosalyn Lai, Yen Ying Lim, Paul Maruff, Terence J. O’Brien, Christopher C. Rowe, Olivier Salvado, Peter W. Schofield, Michael Spino, Fernando Tricta, Aaron Z. Wagen, Robert Williams, Mark Woodward, Ashley I. Bush - JAMA Neurology 2024 cited by 74
- Correlation between plasma and CSF concentrations of kynurenine pathway metabolites in Alzheimer's disease and relationship to amyloid-β and tau
Authors: Kelly R. Jacobs, Chai K. Lim, Kaj Blennow, Henrik Zetterberg, Pratishtha Chatterjee, Ralph N. Martins, Bruce J. Brew, Gilles J. Guillemin, David B. Lovejoy - Neurobiology of Aging 2019 cited by 130
- Kynurenine pathway metabolomics predicts and provides mechanistic insight into multiple sclerosis progression
Authors: Chai K. Lim, Ayse Bilgin, David B. Lovejoy, Vanessa Tan, Sonia Bustamante, Bruce Taylor, Alban Bessede, Bruce J. Brew, Gilles J. Guillemin - Scientific Reports 2017 cited by 261
- Indoleamine 2,3 dioxygenase and quinolinic acid Immunoreactivity in Alzheimer's disease hippocampus
Authors: Gilles J. Guillemin, Bruce J. Brew, Claire Noonan, Osamu Takikawa, Karen M. Cullen - Neuropathology and Applied Neurobiology 2005 cited by 326
- Mechanism for Quinolinic Acid Cytotoxicity in Human Astrocytes and Neurons
Authors: Nady Braidy, Ross Grant, Seray Adams, Bruce J. Brew, Gilles J. Guillemin - Neurotoxicity Research 2009 cited by 226
- Kynurenine pathway metabolism in human astrocytes: a paradox for neuronal protection
Authors: Gilles J. Guillemin, Stephen J. Kerr, George A. Smythe, Danielle G. Smith, Vimal Kapoor, Patricia J. Armati, Juliana Croitoru, Bruce J. Brew - Journal of Neurochemistry 2001 cited by 535
- Recent advances in clinical trials targeting the kynurenine pathway
Authors: Ananda Staats Pires, Gayathri Sundaram, Benjamin Heng, Shivani Krishnamurthy, Bruce J. Brew, Gilles J. Guillemin - Pharmacology & Therapeutics 2021 cited by 87
- The Excitotoxin Quinolinic Acid Induces Tau Phosphorylation in Human Neurons
Authors: Abdur Rahman, Kaka Ting, Karen M. Cullen, Nady Braidy, Bruce J. Brew, Gilles J. Guillemin - PLoS ONE 2009 cited by 247
- Expression of Tryptophan 2,3-Dioxygenase and Production of Kynurenine Pathway Metabolites in Triple Transgenic Mice and Human Alzheimer's Disease Brain
Authors: Wei Wu, Joseph A. Nicolazzo, Wen Li, Roger S. Chung, Roger Stankovic, Shisan Bao, Chai K. Lim, Bruce J. Brew, Karen M. Cullen, Gilles J. Guillemin - PLoS ONE 2013 cited by 213
- Intact HIV Proviruses Persist in the Brain Despite Viral Suppression with ART
Authors: Catherine R. Cochrane, Thomas A. Angelovich, Sarah J. Byrnes, Emily Waring, Aleks C. Guanizo, Gemma S. Trollope, Jingling Zhou, Judith Vue, Lachlan Senior, Emma Wanicek, Janna Jamal Eddine, Matthew J. Gartner, Trisha A. Jenkins, Paul R. Gorry, Bruce J. Brew, Sharon R. Lewin, Jacob D. Estes, Michael Roche, Melissa J. Churchill - Annals of Neurology 2022 cited by 79
- The kynurenine pathway relates to post‐acuteCOVID‐19 objective cognitive impairment andPASC
Authors: Lucette A. Cysique, David Jakabek, Sophia G. Bracken, Yasmin Allen‐Davidian, Benjamin Heng, Sharron Chow, Mona Dehhaghi, Ananda Staats Pires, D.R. Darley, Anthony Byrne, Chansavath Phetsouphanh, Anthony D. Kelleher, Gregory J. Dore, Gail Matthews, Gilles J. Guillemin, Bruce J. Brew - Annals of Clinical and Translational Neurology 2023 cited by 46
- Chronic Meningitis Investigated via Metagenomic Next-Generation Sequencing
Authors: Michael R. Wilson, Brian D. O’Donovan, Jeffrey M. Gelfand, Hannah A. Sample, Felicia C. Chow, John P. Betjemann, Maulik Shah, Megan Richie, Mark Gorman, Rula A. Hajj‐Ali, Leonard H. Calabrese, Kelsey C. Zorn, Eric D. Chow, John Greenlee, Jonathan Blum, Gary Green, Lillian M. Khan, Debarko Banerji, Charles Langelier, Chloe Bryson‐Cahn, Whitney E. Harrington, Jairam R. Lingappa, Niraj M. Shanbhag, Ari Green, Bruce J. Brew, Ariane Soldatos, Luke Strnad, Sarah B. Doernberg, Cheryl A. Jay, Vanja C. Douglas, S. Andrew Josephson, Joseph L. DeRisi - JAMA Neurology 2018 cited by 313
- Interferon-γ Regulates the Proliferation and Differentiation of Mesenchymal Stem Cells via Activation of Indoleamine 2,3 Dioxygenase (IDO)
Authors: Juliana Croitoru‐Lamoury, F. Lamoury, Michael Caristo, Kazuo Suzuki, David W. Walker, Osamu Takikawa, Rosanne M. Taylor, Bruce J. Brew - PLoS ONE 2011 cited by 229
- Implications of the kynurenine pathway and quinolinic acid in Alzheimer's disease
Authors: Gilles J. Guillemin, Bruce J. Brew - Redox Report 2002 cited by 206
- Effect of the Mediterranean diet on cognition and brain morphology and function: a systematic review of randomized controlled trials
Authors: Sue Radd‐Vagenas, Shantel L. Duffy, Sharon L. Naismith, Bruce J. Brew, Victoria Flood, Maria A. Fiatarone Singh - American Journal of Clinical Nutrition 2018 cited by 173
- Involvement of the Kynurenine Pathway in Human Glioma Pathophysiology
Authors: Seray Adams, Charles Teo, Kerrie L. McDonald, Anna Zinger, Sonia Bustamante, Chai K. Lim, Gayathri Sundaram, Nady Braidy, Bruce J. Brew, Gilles J. Guillemin - PLoS ONE 2014 cited by 153
- Quinolinic acid upregulates chemokine production and chemokine receptor expression in astrocytes
Authors: Gilles J. Guillemin, Juliana Croitoru‐Lamoury, Dominique Dormont, Patricia J. Armati, Bruce J. Brew - Glia 2003 cited by 170
- Expression of the Kynurenine Pathway in Human Peripheral Blood Mononuclear Cells: Implications for Inflammatory and Neurodegenerative Disease
Authors: Simon Jones, Nunzio F. Franco, Bianca Varney, Gayathri Sundaram, David A. Brown, Josien de Bie, Chai K. Lim, Gilles J. Guillemin, Bruce J. Brew - PLoS ONE 2015 cited by 141
- Aβ1-42 induces production of quinolinic acid by human macrophages and microglia
Authors: Gilles J. Guillemin, George A. Smythe, Laura A. Veas, Osamu Takikawa, Bruce J. Brew - Neuroreport 2003 cited by 137
- The Kynurenine Pathway in Brain Tumor Pathogenesis
Authors: Seray Adams, Nady Braidy, Alban Bessesde, Bruce J. Brew, Ross Grant, Charlie Teo, Gilles J. Guillemin - Cancer Research 2012 cited by 150
