David A. Brown
Active 1972–2024
- 256
- Papers
- 39,715
- Citations
- 113
- h-index
- 247
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Medicine36.6%
- Biochemistry, Genetics and Molecular Biology31.1%
- Neuroscience19.3%
- Engineering2.2%
- Immunology and Microbiology2.1%
- Environmental Science1.8%
- Other6.9%
Topics
- Neuroscience and Neuropharmacology Research7.5%
- Ion channel regulation and function6.2%
- GDF15 and Related Biomarkers3.3%
- Receptor Mechanisms and Signaling2.2%
- Mitochondrial Function and Pathology2.2%
- Cardiac electrophysiology and arrhythmias2%
- Other76.6%
Coauthors
- Samuel N. Breit48
- Vicky Wang-Wei Tsai20
- Patrick Delmas14
- Asne R. Bauskin13
- Stephen J. Marsh12
- A. A. Selyanko10
- Fe C. Abogadie10
- Támara Kuffner10
- Yasmin Husaini10
- Amanda Sainsbury9
- Christopher P. Marquis9
- Justin B. Perry9
- Heiko Johnen8
- Malcolm P. Caulfield8
- Shu Lin8
- Alexander K. Filippov7
- Hong Ping Zhang7
- Ka Ki Michelle Lee-Ng7
- Lele Jiang7
- Noel J. Buckley7
- Paul R. Adams7
- Rakesh Manandhar7
- Russell L. Moore7
- Andrew Constanti6
All papers
- Mitochondrial function as a therapeutic target in heart failure
Authors: David A. Brown, Justin B. Perry, Mitchell E. Allen, Hani N. Sabbah, Brian L. Stauffer, Saame Raza Shaikh, John G.F. Cleland, Wilson S. Colucci, Javed Butler, Adriaan A. Voors, Stefan D. Anker, Bertram Pitt, Burkert Pieske, Gerasimos Filippatos, Stephen J. Greene, Mihai Gheorghiade - Nature Reviews Cardiology 2016 cited by 790
- The MIC-1/GDF15-GFRAL Pathway in Energy Homeostasis: Implications for Obesity, Cachexia, and Other Associated Diseases
Authors: Vicky Wang-Wei Tsai, Yasmin Husaini, Amanda Sainsbury, David A. Brown, Samuel N. Breit - Cell Metabolism 2018 cited by 413
- Tumor-induced anorexia and weight loss are mediated by the TGF-β superfamily cytokine MIC-1
Authors: Heiko Johnen, Shu Lin, Támara Kuffner, David A. Brown, Vicky Wang-Wei Tsai, Asne R. Bauskin, Liyun Wu, Greg J. Pankhurst, Lele Jiang, Simon Junankar, Mark Hunter, W. Douglas Fairlie, Nicola J. Lee, Ronaldo F. Enriquez, Paul A. Baldock, Eva Corey, Fred S. Apple, MaryAnn M Murakami, En-Ju D. Lin, Chuansong Wang, Matthew J. During, Amanda Sainsbury, Herbert Herzog, Samuel N. Breit - Nature Medicine 2007 cited by 597
- The GDF15-GFRAL Pathway in Health and Metabolic Disease: Friend or Foe?
Authors: Samuel N. Breit, David A. Brown, Vicky Wang-Wei Tsai - Annual Review of Physiology 2020 cited by 205
- Large-scale delineation of secreted protein biomarkers overexpressed in cancer tissue and serum
Authors: John Welsh, Lisa M. Sapinoso, S Kern, David A. Brown, Tao Liu, Asne R. Bauskin, Robyn L. Ward, Nicholas J. Hawkins, David I. Quinn, Pamela J. Russell, Robert L. Sutherland, Samuel N. Breit, Christopher A. Moskaluk, Henry F. Frierson, Garret M. Hampton - National Academy of Sciences, Proceedings of the National Academy of Sciences 2003 cited by 501
- Efficacy and Safety of Elamipretide in Individuals With Primary Mitochondrial Myopathy
Authors: Amel Karaa, Enrico Bertini, Valério Carelli, Bruce H. Cohen, Gregory M. Enns, Marni J. Falk, Amy B. Goldstein, Gráinne S. Gorman, Richard Haas, Michio Hirano, Thomas Klopstock, Mary Kay Koenig, Cornelia Kornblum, Costanza Lamperti, Anna Lehman, Nicola Longo, Mária Judit Molnár, Sumit Parikh, H. Phan, Robert D. S. Pitceathly, Russell P. Saneto, Fernando Scaglia, Serenella Servidei, Mark A. Tarnopolsky, António Toscano, Johan L.K. Van Hove, John Vissing, Jerry Vockley, Jeffrey S. Finman, David A. Brown, James A. Shiffer, Michelango Mancuso, for the MMPOWER-3 Trial Investigators, for the MMPOWER-3 Trial Investigators, Valentino Maria Lucia, P. Alessandro, Sancricca Cristina, Grosz Zoltan, Györgyi Bathori, Daria Diodato, Gessica Vasco, Soler-Alfonso Claudia, Abdullhameed May Ali, Hanna Michael G, Enrico Bugiardini, Poole Olivia, Kendall Fran, A. Noelle Larson, Nithi Ajantha, Engelstad Kristin, Mattman Andre, M Michelle, Bischoff Alamut T, Büchner Boriana, Radelfahr Florentine, Stendel Claudia, Claudia B. Catarino, Tonni Hilary Elizabeth, Rossman Ian Tait, C. Marie, Victorio Maria Christina, Montano Vincenzo, Siciliano Gabriele, M.O. Musumeci Olimpia, Catania Alessina - Neurology 2023 cited by 69
- GDF15/MIC-1 Functions As a Protective and Antihypertrophic Factor Released From the Myocardium in Association With SMAD Protein Activation
Authors: Jian Xu, Thomas R. Kimball, John N. Lorenz, David A. Brown, Asne R. Bauskin, Raisa Klevitsky, Timothy E. Hewett, Samuel N. Breit, Jeffery D. Molkentin - Circulation Research 2006 cited by 503
- Autoimmune psychosis: an international consensus on an approach to the diagnosis and management of psychosis of suspected autoimmune origin
Authors: Thomas Pollak, Belinda Lennox, Sabine Müller, Michael E. Benros, Harald Prüß, Ludger Tebartz van Elst, Hans Klein, Jo hann Steiner, Thomas Frodl, Bernhard Bogerts, Li Tian, Laurent Groc, Alkomiet Hasan, Bernhard T. Baune, Dominique Endres, Ebrahim Haroon, Robert H. Yolken, Francesco Benedetti, Angelos Halaris, Jeffrey H. Meyer, Hans H. Stassen, Marion Leboyer, Dietmar Fuchs, Markus Otto, David A. Brown, Angela Vincent, Souhel Najjar, Karl Bechter - The Lancet Psychiatry 2019 cited by 397
- NeuralKCNQ(Kv7) channels
Authors: David A. Brown, Gayle M. Passmore - British Journal of Pharmacology 2009 cited by 663
- Macrophage Inhibitory Cytokine 1 (MIC-1/GDF15) Decreases Food Intake, Body Weight and Improves Glucose Tolerance in Mice on Normal & Obesogenic Diets
Authors: Laurence Macia, Vicky Wang-Wei Tsai, Amy Nguyen, Heiko Johnen, Támara Kuffner, Yan‐Chuan Shi, Shu Lin, Herbert Herzog, David A. Brown, Samuel N. Breit, Amanda Sainsbury - PLoS ONE 2012 cited by 207
- Associations of serum short-chain fatty acids with circulating immune cells and serum biomarkers in patients with multiple sclerosis
Authors: Stephanie Trend, Jonatan Leffler, Anderson P. Jones, Lilian Cha, Shelley Gorman, David A. Brown, Samuel N. Breit, Allan G. Kermode, Martyn A. French, Natalie C. Ward, Prue H. Hart - Scientific Reports 2021 cited by 70
- Macrophage inhibitory cytokine‐1 (MIC‐1/GDF15): a new marker of all‐cause mortality
Authors: Fredrik Wiklund, Anna M. Bennet, Patrik K. E. Magnusson, Ulrika K. Eriksson, Fredrik Lindmark, Liyun Wu, Nasreen Yaghoutyfam, Christopher P. Marquis, Pär Stattin, Nancy L. Pedersen, Hans‐Olov Adami, Henrik Grönberg, Samuel N. Breit, David A. Brown - Aging Cell 2010 cited by 281
- GDF15 enhances body weight and adiposity reduction in obese mice by leveraging the leptin pathway
Authors: Samuel N. Breit, Rakesh Manandhar, Hongping Zhang, Michelle Lee-Ng, David A. Brown, Vicky Wang-Wei Tsai - Cell Metabolism 2023 cited by 39
- Muscarinic suppression of a novel voltage-sensitive K+ current in a vertebrate neurone
Authors: David A. Brown, Paul R. Adams - Nature 1980 cited by 1,467
- TGF-b Superfamily Cytokine MIC-1/GDF15 Is a Physiological Appetite and Body Weight Regulator
Authors: Vicky Wang-Wei Tsai, Laurence Macia, Heiko Johnen, Támara Kuffner, Rakesh Manadhar, Sebastian B. Jørgensen, Ka Ki Michelle Lee-Ng, Hong Ping Zhang, Liyun Wu, Christopher P. Marquis, Lele Jiang, Yasmin Husaini, Shu Lin, Herbert Herzog, David A. Brown, Amanda Sainsbury, Samuel N. Breit - PLoS ONE 2013 cited by 190
- Target 2035 – update on the quest for a probe for every protein
Authors: Susanne Müller, Suzanne Ackloo, Arij Al Chawaf, Bissan Al‐Lazikani, Albert A. Antolín, Jonathan B. Baell, Hartmut Beck, Shaunna Beedie, Ulrich A. K. Betz, G.A. Bezerra, Paul E. Brennan, David A. Brown, Peter J. Brown, Alex N. Bullock, Adrian J. Carter, A. Chaikuad, Mathilde Chaineau, Alessio Ciulli, Ian Collins, Jan Dreher, David H. Drewry, Kristina Edfeldt, A.M. Edwards, Ursula Egner, Stephen V. Frye, Stephen M. Fuchs, Matthew D. Hall, Ingo V. Hartung, Alexander Hillisch, Stephen Hitchcock, Evert Homan, Natarajan Kannan, James R. Kiefer, Stefan Knapp, Milka Kostić, Stefan Kubicek, Andrew R. Leach, S. Lindemann, Brian D. Marsden, Hisanori Matsui, Jordan L. Meier, Daniel Merk, Maurice Michel, Maxwell R. Morgan, Anke Mueller‐Fahrnow, Dafydd R. Owen, Benjamin Perry, Saul H. Rosenberg, Kumar Singh Saikatendu, Matthieu Schapira, Cora Scholten, Sujata Sharma, Anton Simeonov, M. Sundström, Giulio Superti‐Furga, Matthew H. Todd, Claudia Tredup, Masoud Vedadi, F. von Delft, Timothy M. Willson, Georg E. Winter, Paul Workman, C.H. Arrowsmith - RSC Medicinal Chemistry 2021 cited by 82
- The Anorectic Actions of the TGFβ Cytokine MIC-1/GDF15 Require an Intact Brainstem Area Postrema and Nucleus of the Solitary Tract
Authors: Vicky Wang-Wei Tsai, Rakesh Manandhar, Sebastian B. Jørgensen, Ka Ki Michelle Lee-Ng, Hong Ping Zhang, Christopher P. Marquis, Lele Jiang, Yasmin Husaini, Shu Lin, Amanda Sainsbury, Paul E. Sawchenko, David A. Brown, Samuel N. Breit - PLoS ONE 2014 cited by 123
- Treatment with the TGF-b superfamily cytokine MIC-1/GDF15 reduces the adiposity and corrects the metabolic dysfunction of mice with diet-induced obesity
Authors: Vicky Wang-Wei Tsai, H P Zhang, Rakesh Manandhar, Ka Ki Michelle Lee-Ng, Hélène Lebhar, Christopher P. Marquis, Yasmin Husaini, Amanda Sainsbury, David A. Brown, Samuel N. Breit - International Journal of Obesity 2017 cited by 97
- Risk Factors and Characteristics of Checkpoint Inhibitor–Associated Autoimmune Diabetes Mellitus (CIADM): A Systematic Review and Delineation From Type 1 Diabetes
Authors: Linda Wu, Venessa Tsang, Alexander M. Menzies, Sarah C. Sasson, Matteo S. Carlino, David A. Brown, Roderick Clifton‐Bligh, Jenny E. Gunton - Diabetes Care 2023 cited by 59
- The cardiolipin-binding peptide elamipretide mitigates fragmentation of cristae networks following cardiac ischemia reperfusion in rats
Authors: Mitchell E. Allen, Edward Ross Pennington, Justin B. Perry, Sahil Dadoo, Marina Makrecka‐Kuka, Maija Dambrova, Fatiha Moukdar, Hetal D. Patel, Xianlin Han, Grahame K. Kidd, Emily Benson, Tristan B. Raisch, Steven Poelzing, David A. Brown, Saame Raza Shaikh - Communications Biology 2020 cited by 95
- Pathways modulating neural KCNQ/M (Kv7) potassium channels
Authors: Patrick Delmas, David A. Brown - Nature reviews. Neuroscience 2005 cited by 692
- The role of cardiolipin concentration and acyl chain composition on mitochondrial inner membrane molecular organization and function
Authors: Edward Ross Pennington, Katsuhiko Funai, David A. Brown, Saame Raza Shaikh - Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 2019 cited by 109
- Mechanisms by Which Dietary Fatty Acids Regulate Mitochondrial Structure-Function in Health and Disease
Authors: E. Madison Sullivan, Edward Ross Pennington, William D. Green, Melinda A. Beck, David A. Brown, Saame Raza Shaikh - Advances in Nutrition 2018 cited by 102
- MIC-1 serum level and genotype: associations with progress and prognosis of colorectal carcinoma.
Authors: David A. Brown, Robyn L. Ward, Philip Buckhaults, Tao Liu, Katharine Romans, Nicholas J. Hawkins, Asne R. Bauskin, Kenneth W. Kinzler, Bert Vogelstein, Samuel N. Breit - 2003 cited by 268
