Fred S. Apple

Active 1985–2025

Also published as
Fred S Apple
145
Papers
33,597
Citations
92
h-index
143
i10-index

Citations

Citations per year for Fred S. Apple1987: 3 citations1989: 1 citations1990: 1 citations1992: 5 citations1993: 4 citations1994: 3 citations1995: 9 citations1996: 12 citations1997: 11 citations1998: 24 citations1999: 81 citations2000: 78 citations2001: 67 citations2002: 74 citations2003: 88 citations2004: 135 citations2005: 121 citations2006: 144 citations2007: 182 citations2008: 168 citations2009: 160 citations2010: 190 citations2011: 146 citations2012: 179 citations2013: 196 citations2014: 211 citations2015: 219 citations2016: 250 citations2017: 232 citations2018: 187 citations2019: 911 citations2020: 1,158 citations2021: 980 citations2022: 757 citations2023: 522 citations2024: 908 citations2025: 408 citations2026: 23 citations1988: no citations, so this year is not shown1991: no citations, so this year is not shown

Citation sources

Countries

World map of the countries and regions citing this authorUnited States: 2,159 citing papers, 20.2% of this breakdownUnited Kingdom: 870 citing papers, 8.1% of this breakdownChina: 829 citing papers, 7.7% of this breakdownItaly: 635 citing papers, 5.9% of this breakdownGermany: 607 citing papers, 5.7% of this breakdownCanada: 396 citing papers, 3.7% of this breakdownAustralia: 350 citing papers, 3.3% of this breakdownNetherlands: 345 citing papers, 3.2% of this breakdownSwitzerland: 342 citing papers, 3.2% of this breakdownSpain: 339 citing papers, 3.2% of this breakdownFrance: 303 citing papers, 2.8% of this breakdownJapan: 244 citing papers, 2.3% of this breakdown
0%20.2%Other 30.7%

Fields

  • Medicine83.7%
  • Biochemistry, Genetics and Molecular Biology8.3%
  • Engineering2.2%
  • Immunology and Microbiology1.5%
  • Health Professions0.7%
  • Neuroscience0.5%
  • Other3.1%

Topics

  • Acute Myocardial Infarction Research11.1%
  • Cardiac Imaging and Diagnostics7%
  • Coronary Interventions and Diagnostics4.1%
  • Heart Failure Treatment and Management2.8%
  • Cardiac, Anesthesia and Surgical Outcomes2.6%
  • Cardiovascular Function and Risk Factors2.3%
  • Other70.1%

Coauthors

All papers

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  1. Fourth universal definition of myocardial infarction (2018)

    Authors: , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , P J Devereaux, Jose Luis Zamorano, Bertil Lindahl, William S Weintraub, L Kristin Newby, Renu Virmani, Pascal Vranckx, Don Cutlip, Raymond J Gibbons, Sidney C Smith, Dan Atar, Russell V Luepker, Rose Marie Robertson, Robert O Bonow, P Gabriel Steg, Patrick T O’Gara, Keith A A Fox, David Hasdai, Victor Aboyans, Stephan Achenbach, Stefan Agewall, Thomas Alexander, Alvaro Avezum, Emanuele Barbato, Jean-Pierre Bassand, Eric Bates, John A Bittl, Güenter Breithardt, Héctor Bueno, Raffaele Bugiardini, Mauricio G Cohen, George Dangas, James A de Lemos, Victoria Delgado, Gerasimos Filippatos, Edward Fry, Christopher B Granger, Sigrun Halvorsen, Mark A Hlatky, Borja Ibanez, Stefan James, Adnan Kastrati, Christophe Leclercq, Kenneth W Mahaffey, Laxmi Mehta, Christian Müller, Carlo Patrono, Massimo Francesco Piepoli, Daniel Piñeiro, Marco Roffi, Andrea Rubboli, Samin Sharma, Iain A Simpson, Michael Tendera, Marco Valgimigli, Allard C van der Wal, Stephan Windecker, Mohamed Chettibi, Hamlet Hayrapetyan, Franz Xaver Roithinger, Farid Aliyev, Volha Sujayeva, Marc J Claeys, Elnur Smajić, Petr Kala, Kasper Karmak Iversen, Ehab El Hefny, Toomas Marandi, Pekka Porela, Slobodan Antov and 29 more - European Heart Journal 2018 cited by 5,819

  2. Tumor-induced anorexia and weight loss are mediated by the TGF-β superfamily cytokine MIC-1

    Authors: , , , , , , , , , , , , , , , , , , , , , , , - Nature Medicine 2007 cited by 597

  3. Third Universal Definition of Myocardial Infarction

    Authors: , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , William Wijns, Jean‐Pierre Bassand, P Menasché, Jan Ravkilde, E. Magnus Ohman, Elliott M. Antman, Lars Wallentin, Paul W. Armstrong, Maarten L. Simoons, James L. Januzzi, Markku S. Nieminen, Mihai Gheorghiade, Gerasimos Filippatos, Russell V. Luepker, Stephen P. Fortmann, Wayne D. Rosamond, Daniel Levy, David Wood, Sidney C. Smith, Dayi Hu, J L López-Sendón, Rose Marie Robertson, Douglas Weaver, Michał Tendera, Alfred A. Bové, Alexander Parkhomenko, Elena Vasilieva, Shanti Mendis - Journal of the American College of Cardiology 2012 cited by 2,632

  4. Machine learning for diagnosis of myocardial infarction using cardiac troponin concentrations

    Authors: , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , C. Hammett, Tracey Hawkins, Shanen O’Kane, Kate Parke, Kimberley Ryan, Jessica Schluter, Karin Wild, Desirée Wussler, Òscar Miró, Francisco Javier Martín‐Sánchez, Dagmar I. Keller, Michael Christ, Andreas Buser, María Rubini Giménez, Stephanie Barker, Jennifer Blades, Andrew R. Chapman, Takeshi Fujisawa, Dorien M Kimenai, J Leung, Ziwen Li, Michael McDermott, David E. Newby, Stacey D. Schulberg, Anoop Shah, Andrew Sorbie, Grace Soutar, Fiona E. Strachan, Caelan Taggart, Daniel Perez-Vicencio, Yiqing Wang, Ryan Wereski, Kelly L. Williams, Christopher J. Weir, Colin Berry, Alan Reid, Donogh Maguire, Paul Collinson, Yader Sandoval, Stephen W. Smith - Nature Medicine 2023 cited by 150

  5. High-Sensitivity Cardiac Troponin and the 2021 AHA/ACC/ASE/CHEST/SAEM/SCCT/SCMR Guidelines for the Evaluation and Diagnosis of Acute Chest Pain

    Authors: , , , , , - Circulation 2022 cited by 177

  6. High-sensitivity troponin in the evaluation of patients with suspected acute coronary syndrome: a stepped-wedge, cluster-randomised controlled trial

    Authors: , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , Christopher J. Weir, Nicholas L. Mills, Lucy Marshall, Stacey Stewart, Takeshi Fujisawa, Catalina A. Vallejos, Athanasios Tsanas, Mischa Hautvast, Jean McPherson, Lynn McKinlay, Jonathan Malo, Colin Fischbacher, Bernard Croal, Stephen J Leslie, Allan Walker, Tony Wackett, Roma A. Armstrong, Laura Stirling, Claire MacDonald, Imran Sadat, Frank Finlay, Heather Charles, Pamela Linksted, Stephen G. Young, Bill Alexander, Chris Duncan - The Lancet 2018 cited by 380

  7. Machine Learning to Predict the Likelihood of Acute Myocardial Infarction

    Authors: , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , Nils A. Sörensen, Francisco Ojeda - Circulation 2019 cited by 233

  8. Clinical Laboratory Practice Recommendations for the Use of Cardiac Troponin in Acute Coronary Syndrome: Expert Opinion from the Academy of the American Association for Clinical Chemistry and the Task Force on Clinical Applications of Cardiac Bio-Markers of the International Federation of Clinical Chemistry and Laboratory Medicine

    Authors: , , , , , , - Clinical Chemistry 2018 cited by 436

  9. Single High-Sensitivity Point-of-Care Whole-Blood Cardiac Troponin I Measurement to Rule Out Acute Myocardial Infarction at Low Risk

    Authors: , , , , , , , , , , , , , , , , , , , , , , , , , , - Circulation 2022 cited by 79

  10. High-Sensitivity Cardiac Troponin on Presentation to Rule Out Myocardial Infarction: A Stepped-Wedge Cluster Randomized Controlled Trial

    Authors: , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , Colin Fischbacher, Ian Ford, Takeshi Fujisawa, Ronnie Harkess, Dorien M Kimenai, Stephen J Leslie, Pamela Linksted, Matthew T.H. Lowry, Claire MacDonald, Lucy Marshall, Filip Mendusic, John Norrie, Imran Sadat, Catherine L. Stables, Jennifer S. Stevens, Stacey Stewart, Laura Stirling, Caelan Taggart, Ryan Wereski, Stephen G. Young - Circulation 2021 cited by 165

  11. High sensitivity cardiac troponin and the under-diagnosis of myocardial infarction in women: prospective cohort study

    Authors: , , , , , , , , , , , , , , , , - BMJ 2015 cited by 450

  12. Cardiac Troponin Assays: Guide to Understanding Analytical Characteristics and Their Impact on Clinical Care

    Authors: , , , - Clinical Chemistry 2016 cited by 394

  13. High-sensitivity cardiac troponin I at presentation in patients with suspected acute coronary syndrome: a cohort study

    Authors: , , , , , , , , , , , , , , , , , , , - The Lancet 2015 cited by 510

  14. Liberal or Restrictive Transfusion in High-Risk Patients after Hip Surgery

    Authors: , , , , , , , , , , , , , , , , , - New England Journal of Medicine 2011 cited by 1,305

  15. Analytical Characteristics of High-Sensitivity Cardiac Troponin Assays

    Authors: , - Clinical Chemistry 2011 cited by 846

  16. Association of High-Sensitivity Cardiac Troponin I Concentration With Cardiac Outcomes in Patients With Suspected Acute Coronary Syndrome

    Authors: , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , Frederick K. Korley, Thomas S. Metkus, Yader Sandoval, Fred S. Apple, David E. Newby, Anoop Shah, Nicholas L. Mills - JAMA 2017 cited by 249

  17. Analytical Considerations in Deriving 99th Percentile Upper Reference Limits for High-Sensitivity Cardiac Troponin Assays: Educational Recommendations from the IFCC Committee on Clinical Application of Cardiac Bio-Markers

    Authors: , , , , , , , , , - Clinical Chemistry 2022 cited by 102

  18. IFCC educational materials on selected analytical and clinical applications of high sensitivity cardiac troponin assays

    Authors: , , , , , , , , , - Clinical Biochemistry 2014 cited by 281

  19. High-sensitivity cardiac troponin assays for cardiovascular risk stratification in the general population

    Authors: , , - European Heart Journal 2020 cited by 133

  20. Sex-Specific Thresholds of High-Sensitivity Troponin in Patients With Suspected Acute Coronary Syndrome

    Authors: , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , Andrew R. Chapman, Dennis Sandeman, Philip D Adamson, Catherine L. Stables, Catalina A. Vallejo, Athanasios Tsanasis, Lucy Marshall, Stacey Stewart, Takeshi Fujisawa, Mischa Hautvast, Jean McPherson, Lynn McKinlay, Nicholas L. Mills, David E. Newby, Keith A.A. Fox, Colin Berry, Simon Walker, Christopher J. Weir, Ian Ford, Nicholas L. Mills, David E. Newby, Alasdair Gray, Keith A.A. Fox, Colin Berry, Simon Walker, Paul Collinson, Fred S. Apple, Alan Reid, Anne Cruikshank, Iain Findlay, Shannon Amoils, David McAllister, Donogh Maguire, Jennifer S. Stevens, John Norrie, Christopher J. Weir, Anoop Shah, Atul Anand, Andrew R. Chapman, Kuan Ken Lee, Jack Andrews, Philip D Adamson, Alastair J. Moss, Mohamed Anwar, John Hung, Nicholas L. Mills, Simon Walker, Jonathan Malo, Alan Reid, Anne Cruikshank, Paul Collinson, Colin Fischbacher, Bernard Croal, Stephen J Leslie, Catriona Keerie, Richard Parker, Allan Walker, Ronnie Harkess, Christopher Tuck, Tony Wackett, Christopher J. Weir, Roma A. Armstrong, Marion Flood, Laura Stirling, Claire MacDonald, Imran Sadat, Frank Finlay, Heather Charles, Pamela Linksted, Stephen G. Young and 2 more - Journal of the American College of Cardiology 2019 cited by 128

  21. Cardiac Troponin Thresholds and Kinetics to Differentiate Myocardial Injury and Myocardial Infarction

    Authors: , , , , , , , , , , , , , - Circulation 2021 cited by 92

  22. High-Sensitivity Cardiac Troponin and the Universal Definition of Myocardial Infarction

    Authors: , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , Takeshi Fujisawa, Mischa Hautvast, Jean McPherson, Lynn McKinlay, Simon Walker, Ian Ford, Simon Walker, Shannon Amoils, Jennifer S. Stevens, John Norrie, Jack R. Andrews, P B Adamson, Alastair J. Moss, Mohamed Anwar, John Hung, Simon Walker, Jonathan Malo, Colin Fischbacher, Bernard Croal, Stephen J Leslie, Richard Parker, Allan Walker, Ronnie Harkess, Christopher Tuck, Tony Wackett, Roma A. Armstrong, Marion Flood, Laura Stirling, Claire MacDonald, Imran Sadat, Frank Finlay, Heather Charles, Pamela Linksted, Stephen G. Young, Bill Alexander, Chris Duncan - Circulation 2019 cited by 202

  23. Myocardial Injury in the Era of High-Sensitivity Cardiac Troponin Assays

    Authors: , , , , , , - JAMA Cardiology 2019 cited by 135

  24. Sex-Specific 99th Percentile Upper Reference Limits for High Sensitivity Cardiac Troponin Assays Derived Using a Universal Sample Bank

    Authors: , , , , , , , , - Clinical Chemistry 2020 cited by 115