C. Dirk Keene

Active 1995–2026

203
Papers
30,491
Citations
80
h-index
190
i10-index

Citations

Citations per year for C. Dirk Keene1983: 1 citations1996: 1 citations1997: 1 citations1998: 1 citations1999: 2 citations2000: 3 citations2001: 6 citations2002: 35 citations2003: 178 citations2004: 177 citations2005: 196 citations2006: 184 citations2007: 164 citations2008: 167 citations2009: 144 citations2010: 109 citations2011: 117 citations2012: 82 citations2013: 80 citations2014: 60 citations2015: 52 citations2016: 85 citations2017: 162 citations2018: 162 citations2019: 594 citations2020: 1,088 citations2021: 1,220 citations2022: 1,336 citations2023: 1,473 citations2024: 2,374 citations2025: 1,397 citations2026: 67 citations1984–1995: no citations, so these years are not shown

Citation sources

Countries

World map of the countries and regions citing this authorUnited States: 5,287 citing papers, 32.4% of this breakdownChina: 1,379 citing papers, 8.4% of this breakdownUnited Kingdom: 1,219 citing papers, 7.5% of this breakdownGermany: 882 citing papers, 5.4% of this breakdownCanada: 718 citing papers, 4.4% of this breakdownItaly: 533 citing papers, 3.3% of this breakdownAustralia: 490 citing papers, 3% of this breakdownSweden: 457 citing papers, 2.8% of this breakdownNetherlands: 449 citing papers, 2.7% of this breakdownFrance: 423 citing papers, 2.6% of this breakdownSpain: 419 citing papers, 2.6% of this breakdownJapan: 409 citing papers, 2.5% of this breakdown
0%32.4%Other 22.4%

Fields

  • Medicine49.3%
  • Biochemistry, Genetics and Molecular Biology24.1%
  • Neuroscience20.7%
  • Immunology and Microbiology1.2%
  • Engineering1.2%
  • Computer Science1.1%
  • Other2.4%

Topics

  • Alzheimer's disease research and treatments7.3%
  • Neuroinflammation and Neurodegeneration Mechanisms5.3%
  • Mesenchymal stem cell research4.3%
  • Dementia and Cognitive Impairment Research3.5%
  • Single-cell and spatial transcriptomics3%
  • Traumatic Brain Injury Research2.3%
  • Other74.3%

Coauthors

All papers

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  1. Conserved cell types with divergent features in human versus mouse cortex

    Authors: , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , C. Dirk Keene, Mohamed Keshk, Andrew L. Ko, Kanan Lathia, Ahmed Mahfouz, Zoe Maltzer, Mary McGraw, Thuc Nghi Nguyen, Julie Nyhus, Jeffrey G. Ojemann, Aaron Oldre, Sheana Parry, Shannon Reynolds, Christine Rimorin, Nadiya V. Shapovalova, Saroja Somasundaram, Aaron Szafer, Elliot R. Thomsen, Michael Tieu, Gerald Quon, Richard H. Scheuermann, Rafael Yuste, Susan M. Sunkin, Boudewijn P. F. Lelieveldt, David Feng, Lydia Ng, Amy Bernard, Michael Hawrylycz, John W. Phillips, Bosiljka Tasic, Hongkui Zeng, Allan R. Jones, Christof Koch, Ed S. Lein - Nature 2019 cited by 1,988

  2. Transcriptomic diversity of cell types across the adult human brain

    Authors: , , , , , , , , , , , , , , , , , , , , - Science 2023 cited by 799

  3. Limbic-predominant age-related TDP-43 encephalopathy (LATE): consensus working group report

    Authors: , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , William W. Seeley, Reisa A. Sperling, Charles L. White, Lei Yu, Julie A. Schneider - Brain 2019 cited by 1,546

  4. Comparative cellular analysis of motor cortex in human, marmoset and mouse

    Authors: , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , Lucas T. Graybuck, Brian R. Herb, Xiaomeng Hou, Jayaram Kancherla, Matthew Kroll, Kanan Lathia, Baldur van Lew, Yang Eric Li, Christine S. Liu, Hanqing Liu, Jacinta Lucero, Anup Mahurkar, Delissa McMillen, Jeremy A. Miller, Marmar R. Moussa, Joseph R. Nery, Philip R. Nicovich, Sheng-Yong Niu, Joshua Orvis, Julia Osteen, Scott F. Owen, Carter R. Palmer, Thanh Pham, Nongluk Plongthongkum, Olivier Poirion, Nora Reed, Christine Rimorin, Angeline Rivkin, William J. Romanow, Adriana E. Sedeño-Cortés, Kimberly Siletti, Saroja Somasundaram, Josef Šulc, Michael Tieu, Amy Torkelson, Herman Tung, Xinxin Wang, Fangming Xie, Anna Marie Yanny, Renee Zhang, Seth A. Ament, M. Margarita Behrens, Héctor Corrada Bravo, Jerold Chun, Alexander Dobin, Jesse Gillis, Ronna Hertzano, Patrick R. Hof, Thomas Höllt, Gregory D. Horwitz, C. Dirk Keene, Peter V. Kharchenko, Andrew L. Ko, Boudewijn P. F. Lelieveldt, Chongyuan Luo, Eran A. Mukamel, António Pinto‐Duarte, Sebastian Preißl, Aviv Regev, Bing Ren, Richard H. Scheuermann, Kimberly A. Smith, William J. Spain, Owen White, Christof Koch, Michael Hawrylycz, Bosiljka Tasic, Evan Z. Macosko, Steven A. McCarroll, Jonathan T. Ting and 6 more - Nature 2021 cited by 866

  5. A multimodal cell census and atlas of the mammalian primary motor cortex

    Authors: , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , X. William Yang, Kun Zhang, Principal manuscript editors, Manuscript writing and figure generation, Trygve E. Bakken, Philipp Berens, Tanya L. Daigle, Julie A. Harris, Nikolas L. Jorstad, Brian Kalmbach, Dmitry Kobak, Yang Eric Li, Hanqing Liu, Katherine S. Matho, Eran A. Mukamel, Maitham Naeemi, Federico Scala, Pengcheng Tan, Jonathan T. Ting, Fangming Xie, Meng Zhang, Zhuzhu Zhang, Jingtian Zhou, Brian Zingg, Analysis coordination, Integrated data analysis, Ethan J. Armand, Zizhen Yao, scRNA-seq and snRNA-seq data generation and processing, Darren Bertagnolli, Tamara Casper, Kirsten Crichton, Nick Dee, Dinh Diep, Song‐Lin Ding, Weixiu Dong, Elizabeth L. Dougherty, Olivia Fong, Melissa Goldman, Jeff Goldy, Rebecca D. Hodge, Lijuan Hu, C. Dirk Keene, Fenna M. Krienen, Matthew Kroll, Blue B. Lake, Kanan Lathia, Sten Linnarsson, Christine S. Liu, Evan Z. Macosko, Steven A. McCarroll, Delissa McMillen, Naeem Nadaf, Thuc Nghi Nguyen, Carter R. Palmer, Thanh Pham, Nongluk Plongthongkum, Nora Reed, Aviv Regev, Christine Rimorin, William J. Romanow, Stephen Savoia, Kimberly Siletti, Kimberly A. Smith, Josef Šulc, Bosiljka Tasic, Michael Tieu, Amy Torkelson, Herman Tung, Cindy T. J. van Velthoven and 180 more - Nature 2021 cited by 571

  6. TREM2 Haplodeficiency in Mice and Humans Impairs the Microglia Barrier Function Leading to Decreased Amyloid Compaction and Severe Axonal Dystrophy

    Authors: , , , , , , , , , - Neuron 2016 cited by 824

  7. An anatomic transcriptional atlas of human glioblastoma

    Authors: , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , John G. Hohmann, Parvinder Hothi, Robert Howard, Kevin Joines, Ali Kriedberg, Leonard Kuan, Chris Lau, Felix Lee, Hwahyung Lee, Tracy Lemon, Fuhui Long, Naveed Mastan, Erika Mott, Chantal Murthy, Kiet Ngo, Eric N. Olson, Melissa Reding, Zack L. Riley, David Rosen, David Sandman, Nadiya V. Shapovalova, Clifford R. Slaughterbeck, Andrew Sodt, Graham Stockdale, Aaron Szafer, Wayne Wakeman, Paul Wohnoutka, Steven J. White, D. C. B. Marsh, Robert Rostomily, Lydia Ng, Chinh Dang, Allan R. Jones, Bart P. Keogh, Haley Gittleman, Jill S. Barnholtz‐Sloan, Patrick J. Cimino, Megha Uppin, C. Dirk Keene, Farrokh Farrokhi, Justin D. Lathia, Michael E. Berens, Antonio Iavarone, Amy Bernard, Ed S. Lein, John W. Phillips, Steven Rostad, Charles Cobbs, Michael Hawrylycz, Greg Foltz - Science 2018 cited by 706

  8. Traumatic Brain Injury and Risk of Neurodegenerative Disorder

    Authors: , , , , - Biological Psychiatry 2021 cited by 404

  9. Exceptionally low likelihood of Alzheimer’s dementia in APOE2 homozygotes from a 5,000-person neuropathological study

    Authors: , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , Tatiana M. Foroud, Jonathan L. Haines, Richard Mayeux, Margaret A. Pericak‐Vance, Julie A. Schneider, John Q. Trojanowski, Lindsay A. Farrer, Gerard D. Schellenberg, Gary W. Beecham, Thomas J. Montine, Gyungah Jun, Erin L. Abner, Perrie M. Adams, Marilyn S. Albert, Roger L. Albin, Liana G. Apostolova, Steven E. Arnold, Sanjay Asthana, Craig Atwood, Clinton T. Baldwin, Robert C. Barber, Lisa L. Barnes, Sandra Barral, James T. Becker, Duane Beekly, Eileen H. Bigio, Thomas D. Bird, Deborah Blacker, Bradley F. Boeve, James D. Bowen, Adam Boxer, James R. Burke, Jeffrey M. Burns, Nigel J. Cairns, Laura B. Cantwell, Chuanhai Cao, Chris Carlson, Cynthia M. Carlsson, Regina M. Carney, Minerva M. Carrasquillo, Helena C. Chui, David H. Cribbs, Elizabeth Crocco, Carlos Cruchaga, Charles DeCarli, Malcolm Dick, Rachelle S. Doody, Ranjan Duara, Nilüfer Ertekin‐Taner, Denis A. Evans, Kelley Faber, Thomas Fairchild, Kenneth B. Fallon, David W. Fardo, Martin R. Farlow, Steven H. Ferris, Douglas Galasko, Marla Gearing, Daniel H. Geschwind, Valentina Ghisays, Alison Goate, Neill R. Graff‐Radford, Robert C. Green, John H. Growdon, Håkon Håkonarson, Ronald L. Hamilton, Kara L. Hamilton‐Nelson, Lindy E. Harrell, Lawrence S. Honig, Ryan M. Huebinger and 92 more - Nature Communications 2020 cited by 490

  10. Local connectivity and synaptic dynamics in mouse and human neocortex

    Authors: , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , Samuel Dingman Lee, Kiet Ngo, Philip R. Nicovich, Lydia Potekhina, Shea Ransford, Amanda Gary, Jeff Goldy, Delissa McMillen, Trangthanh Pham, Michael Tieu, La’Akea Siverts, Miranda Walker, Colin Farrell, Martin Schroedter, Cliff Slaughterbeck, Charles Cobb, Richard G. Ellenbogen, Ryder P. Gwinn, C. Dirk Keene, Andrew L. Ko, Jeffrey G. Ojemann, Daniel L. Silbergeld, Daniel Carey, Tamara Casper, Kirsten Crichton, Michael Clark, Nick Dee, Lauren Ellingwood, Jessica Gloe, Matthew Kroll, Josef Šulc, Herman Tung, Katherine Wadhwani, Krissy Brouner, Tom Egdorf, Michelle Maxwell, Mary McGraw, Christina Alice Pom, Augustin Ruiz, Jasmine Bomben, David Feng, Nika Hejazinia, Shi Shu, Aaron Szafer, Wayne Wakeman, John W. Phillips, Amy Bernard, Luke Esposito, Florence D. D’Orazi, Susan M. Sunkin, Kimberly A. Smith, Bosiljka Tasic, Anton Arkhipov, Staci A. Sorensen, Ed S. Lein, Christof Koch, Gabe J. Murphy, Hongkui Zeng, Tim Jarsky - Science 2022 cited by 387

  11. Neuropathological and genetic correlates of survival and dementia onset in synucleinopathies: a retrospective analysis

    Authors: , , , , , , , , , , , , , , , , , , , , , , , - The Lancet Neurology 2016 cited by 591

  12. A comparative atlas of single-cell chromatin accessibility in the human brain

    Authors: , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , Trygve E. Bakken, Boaz P. Levi, C. Dirk Keene, Jingbo Shang, Ed S. Lein, Allen Wang, M. Margarita Behrens, Joseph R. Ecker, Bing Ren - Science 2023 cited by 156

  13. Transcriptomic cytoarchitecture reveals principles of human neocortex organization

    Authors: , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , Michael Tieu, Amy Torkelson, Herman Tung, Edward M. Callaway, Patrick R. Hof, C. Dirk Keene, Boaz P. Levi, Sten Linnarsson, Partha P. Mitra, Kimberly A. Smith, Rebecca D. Hodge, Trygve E. Bakken, Ed S. Lein - Science 2023 cited by 194

  14. LATE-NC staging in routine neuropathologic diagnosis: an update

    Authors: , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , Melissa E. Murray, Liisa Myllykangas, Sukriti Nag, Janna H. Neltner, Kathy L. Newell, Robert A. Rissman, Yuko Saito, S. Ahmad Sajjadi, Katherine E. Schwetye, Andrew F. Teich, Dietmar Rudolf Thal, Sandra O. Tomé, Juan C. Troncoso, Shih‐Hsiu J. Wang, Charles L. White, Thomas Wısnıewskı, Hyun‐Sik Yang, Julie A. Schneider, Dennis W. Dickson, Manuela Neumann - Acta Neuropathologica 2022 cited by 176

  15. Functional Outcomes Over the First Year After Moderate to Severe Traumatic Brain Injury in the Prospective, Longitudinal TRACK-TBI Study

    Authors: , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , Raquel C. Gardner, Étienne Gaudette, Dana P. Goldman, Luis González, Shankar Gopinath, Rao P. Gullapalli, J. Claude Hemphill, Gillian Hotz, Sonia Jain, C. Dirk Keene, Frederick K. Korley, Joel R. Kramer, Natalie Kreitzer, Christopher J. Lindsell, Joan Machamer, Christopher J. Madden, Alastair J. Martin, Thomas W. McAllister, Randall E. Merchant, Laura B. Ngwenya, Florence Noël, Amber Nolan, Eva Palacios, Daniel P. Perl, Ava M. Puccio, Miri Rabinowitz, Jonathan Rosand, Angelle M. Sander, Gabriella Satris, David M. Schnyer, Seth A. Seabury, Mark Sherer, Arthur W. Toga, Alex B. Valadka, Kevin Wang, John K. Yue, Esther L. Yuh, Ross Zafonte - JAMA Neurology 2021 cited by 397

  16. The first NINDS/NIBIB consensus meeting to define neuropathological criteria for the diagnosis of chronic traumatic encephalopathy

    Authors: , , , , , , , , , , , , , , , , - Acta Neuropathologica 2015 cited by 892

  17. Comparative transcriptomics reveals human-specific cortical features

    Authors: , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , William D. Hopkins, Thomas Höllt, C. Dirk Keene, Sten Linnarsson, Steven A. McCarroll, Boudewijn P. F. Lelieveldt, Chet C. Sherwood, Kimberly A. Smith, Christopher A. Walsh, Alexander Dobin, Jesse Gillis, Ed S. Lein, Rebecca D. Hodge, Trygve E. Bakken - Science 2023 cited by 194

  18. Clonal hematopoiesis is associated with protection from Alzheimer’s disease

    Authors: , , , , , , , , , , , , , , , , , , , , , , , , , , , , , - Nature Medicine 2023 cited by 148

  19. Single-cell DNA methylation and 3D genome architecture in the human brain

    Authors: , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , Song‐Lin Ding, Rebecca D. Hodge, Boaz P. Levi, C. Dirk Keene, Sten Linnarsson, Ed S. Lein, Bing Ren, M. Margarita Behrens, Joseph R. Ecker - Science 2023 cited by 156

  20. The Second NINDS/NIBIB Consensus Meeting to Define Neuropathological Criteria for the Diagnosis of Chronic Traumatic Encephalopathy

    Authors: , , , , , , , , , , , , , , , , , , , , , , , , - Journal of Neuropathology & Experimental Neurology 2021 cited by 320

  21. Frequency of LATE neuropathologic change across the spectrum of Alzheimer’s disease neuropathology: combined data from 13 community-based or population-based autopsy cohorts

    Authors: , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , Billie J. Matchett, Fiona E. Matthews, Richard L. Merrick, Thomas J. Montine, Melissa E. Murray, Liisa Myllykangas, Sukriti Nag, Ruth S. Nelson, Janna H. Neltner, Aivi T. Nguyen, Ronald C. Petersen, Tuomo Polvikoski, R. Ross Reichard, Roberta Diehl Rodriguez, Cláudia Kimie Suemoto, Shih‐Hsiu J. Wang, Stephen B. Wharton, Lon R. White, Julie A. Schneider - Acta Neuropathologica 2022 cited by 164

  22. Functional enhancer elements drive subclass-selective expression from mouse to primate neocortex

    Authors: , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , Andrew L. Ko, Jeffrey G. Ojemann, C. Dirk Keene, Daniel L. Silbergeld, Susan M. Sunkin, Viviana Gradinaru, Gregory D. Horwitz, Hongkui Zeng, Bosiljka Tasic, Ed S. Lein, Jonathan T. Ting, Boaz P. Levi - Cell Reports 2021 cited by 196

  23. Human microglia show unique transcriptional changes in Alzheimer’s disease

    Authors: , , , , , , , , , , , , , , , , , , - Nature Aging 2023 cited by 158

  24. Signature morphoelectric properties of diverse GABAergic interneurons in the human neocortex

    Authors: , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , Lauren Kruse, Michael Kunst, Gabriela León, Brian Long, Matthew Mallory, Michelle Maxwell, Mary McGraw, Delissa McMillen, Erica J. Melief, Gábor Molnár, Marty Mortrud, Dakota Newman, Julie Nyhus, Ximena Opitz-Araya, Attila Ozsvár, Trangthanh Pham, Christina Alice Pom, Lydia Potekhina, Ram Rajanbabu, Augustin Ruiz, Susan M. Sunkin, Ildikó Szöts, Naz Taskin, Bargavi Thyagarajan, Michael Tieu, Jessica Trinh, Sara Vargas, David Vumbaco, Femke Waleboer, Sarah Walling-Bell, Natalie Weed, Grace Williams, Julia Wilson, Shenqin Yao, Tingfa Zhou, Pál Barzó, Trygve E. Bakken, Charles Cobbs, Nick Dee, Richard G. Ellenbogen, Luke Esposito, Manuel Ferreira, Nathan W. Gouwens, Benjamin L. Grannan, Ryder P. Gwinn, Jason S. Hauptman, Rebecca D. Hodge, Tim Jarsky, C. Dirk Keene, Andrew L. Ko, Anders Rosendal Korshoej, Boaz P. Levi, Kaare Meier, Jeffrey G. Ojemann, Anoop P. Patel, Jacob Ruzevick, Daniel L. Silbergeld, Kimberly A. Smith, Jens Christian Hedemann Sørensen, Jack Waters, Hongkui Zeng, Jim Berg, Marco Capogna, Natalia A. Goriounova, Brian Kalmbach, Christiaan P. J. de Kock, Huibert D. Mansvelder, Staci A. Sorensen, Gábor Tamás, Ed S. Lein and 1 more - Science 2023 cited by 121