litlas
Log inCreate account

Edward B. Lee

Active 1999–2025

Also published as
Edward B Lee
220
Papers
22,839
Citations
79
h-index
190
i10-index

Citations

Citations per year for Edward B. Lee1976: 1 citations2000: 4 citations2001: 8 citations2002: 4 citations2003: 19 citations2004: 18 citations2005: 35 citations2006: 68 citations2007: 52 citations2008: 41 citations2009: 60 citations2010: 68 citations2011: 88 citations2012: 137 citations2013: 134 citations2014: 139 citations2015: 155 citations2016: 193 citations2017: 249 citations2018: 262 citations2019: 754 citations2020: 895 citations2021: 1,114 citations2022: 1,105 citations2023: 1,129 citations2024: 1,929 citations2025: 1,377 citations2026: 105 citations1977–1999: no citations, so these years are not shown

Citation sources

Countries

World map of the countries and regions citing this authorUnited States: 3,649 citing papers, 28.7% of this breakdownUnited Kingdom: 1,136 citing papers, 9% of this breakdownChina: 1,135 citing papers, 8.9% of this breakdownGermany: 730 citing papers, 5.8% of this breakdownCanada: 550 citing papers, 4.3% of this breakdownItaly: 536 citing papers, 4.2% of this breakdownSweden: 397 citing papers, 3.1% of this breakdownAustralia: 391 citing papers, 3.1% of this breakdownSpain: 384 citing papers, 3% of this breakdownNetherlands: 365 citing papers, 2.9% of this breakdownFrance: 356 citing papers, 2.8% of this breakdownJapan: 343 citing papers, 2.7% of this breakdown
0%28.7%Other 21.5%

Institutions

Fields

  • Medicine62.3%
  • Biochemistry, Genetics and Molecular Biology21.5%
  • Neuroscience12.1%
  • Computer Science1.2%
  • Agricultural and Biological Sciences0.6%
  • Immunology and Microbiology0.5%
  • Other1.8%

Topics

  • Alzheimer's disease research and treatments12.6%
  • Amyotrophic Lateral Sclerosis Research8.2%
  • Parkinson's Disease Mechanisms and Treatments5.6%
  • Dementia and Cognitive Impairment Research4.6%
  • Neuroinflammation and Neurodegeneration Mechanisms3.9%
  • Neurogenetic and Muscular Disorders Research3.4%
  • Other61.7%

Coauthors

All papers

Open in search
  1. SpaGCN: Integrating gene expression, spatial location and histology to identify spatial domains and spatially variable genes by graph convolutional network

    Authors: Jian Hu, Xiangjie Li, Kyle Coleman, Amelia Schroeder, Nan Ma, David J. Irwin, Edward B. Lee, Russell T. Shinohara, Mingyao Li - Nature Methods 2021 cited by 1,095

  2. Large-scale proteomic analysis of Alzheimer’s disease brain and cerebrospinal fluid reveals early changes in energy metabolism associated with microglia and astrocyte activation

    Authors: Erik C. B. Johnson, Eric B. Dammer, Duc M. Duong, Lingyan Ping, Maotian Zhou, Luming Yin, Lenora A. Higginbotham, Andrew Guajardo, Bartholomew White, Juan C. Troncoso, Madhav Thambisetty, Thomas J. Montine, Edward B. Lee, John Q. Trojanowski, Thomas G. Beach, Eric M. Reiman, Vahram Haroutunian, Minghui Wang, Eric E. Schadt, Bin Zhang, Dennis W. Dickson, Nilüfer Ertekin‐Taner, Todd E. Golde, Vladislav Petyuk, Philip L. De Jager, David A. Bennett, Thomas S. Wingo, Srikant Rangaraju, Ihab Hajjar, Joshua M. Shulman, James J. Lah, Allan I. Levey, Nicholas T. Seyfried - Nature Medicine 2020 cited by 1,060

  3. TDP-43 loss and ALS-risk SNPs drive mis-splicing and depletion of UNC13A

    Authors: Anna‐Leigh Brown, Oscar G. Wilkins, Matthew J. Keuss, Sarah E. Hill, Matteo Zanovello, Weaverly Colleen Lee, Alexander Bampton, Flora Lee, Laura Masino, Yue Qi, Sam Bryce-Smith, Ariana Gatt, Martina Hallegger, Delphine Fagegaltier, Hemali Phatnani, Hemali Phatnani, Justin Kwan, Dhruv Sareen, James R. Broach, Zachary Simmons, Ximena Arcila-Londono, Edward B. Lee, Vivianna M. Van Deerlin, Neil A. Shneider, Ernest Fraenkel, Lyle W. Ostrow, Frank Baas, Noah Zaitlen, James D. Berry, Andrea Malaspina, Pietro Fratta, Gregory A. Cox, Leslie M. Thompson, Steven Finkbeiner, Efthimios Dardiotis, Timothy M. Miller, Siddharthan Chandran, Suvankar Pal, Eran Hornstein, Daniel J. MacGowan, Terry Heiman‐Patterson, Molly Hammell, Nikolaos A. Patsopoulos, Oleg Butovsky, Josh Dubnau, Avindra Nath, Robert Bowser, Matthew B. Harms, Eleonora Aronica, Mary Poss, Jennifer E. Phillips‐Cremins, John F. Crary, Nazem Atassi, Dale J. Lange, Darius J. Adams, Leonidas Stefanis, Marc Gotkine, Robert H. Baloh, Suma Babu, Towfique Raj, Sabrina Paganoni, Ophir Shalem, Colin Smith, Bin Zhang, Brent T. Harris, Iris Broce, Vivian E. Drory, John Ravits, Corey T. McMillan, Vilas Menon, Lani F. Wu, Steven J. Altschuler, Yossef Lerner, Rita Sattler, Kendall Van Keuren‐Jensen, Orit Rozenblatt–Rosen, Kerstin Lindblad‐Toh, Katharine Nicholson, Peter K. Gregersen, Jeong‐Ho Lee, Sulev Kõks, Stephen Muljo, Jia Newcombe, Emil K. Gustavsson, Sahba Seddighi, Joel F. Reyes, Steven L. Coon, Daniel M. Ramos, Giampietro Schiavo, Elizabeth Fisher, Towfique Raj, Maria Secrier, Tammaryn Lashley, Jernej Ule, Emanuele Buratti, Jack Humphrey, Michael E. Ward, Pietro Fratta - Nature 2022 cited by 514

  4. Neurodegenerative disease concomitant proteinopathies are prevalent, age-related and APOE4-associated

    Authors: John Robinson, Edward B. Lee, Sharon X. Xie, Lior Rennert, EunRan Suh, Colin Bredenberg, Carrie Caswell, Vivianna M. Van Deerlin, Ning Yan, Ahmed H. Yousef, Howard I. Hurtig, Andrew Siderowf, Murray Grossman, Corey T. McMillan, Bruce L. Miller, John E. Duda, David J. Irwin, David A. Wolk, Lauren Elman, Leo McCluskey, Alice Chen‐Plotkin, Daniel Weintraub, Steven E. Arnold, Johannes Brettschneider, Virginia M.‐Y. Lee, John Q. Trojanowski - Brain 2018 cited by 737

  5. Inferring super-resolution tissue architecture by integrating spatial transcriptomics with histology

    Authors: Daiwei Zhang, Amelia Schroeder, Hanying Yan, Haochen Yang, Jian Hu, Michelle Y. Y. Lee, Kyung S. Cho, Katalin Suszták, Xiaowei Xu, Michael D. Feldman, Edward B. Lee, Emma E. Furth, Linghua Wang, Mingyao Li - Nature Biotechnology 2024 cited by 187

  6. Neuropathological consensus criteria for the evaluation of Lewy pathology in post-mortem brains: a multi-centre study

    Authors: Johannes Attems, Jon B. Toledo, Lauren Walker, Ellen Gelpí, Steve Gentleman, Glenda M. Halliday, Tibor Hortobágyi, K. A. Jellinger, Gábor G. Kovács, Edward B. Lee, Seth Love, Kirsty E. McAleese, Peter T. Nelson, Manuela Neumann, Laura Parkkinen, Tuomo Polvikoski, Beata Sikorska, Colin Smith, Lea T. Grinberg, Dietmar Rudolf Thal, John Q. Trojanowski, Ian G. McKeith - Acta Neuropathologica 2021 cited by 276

  7. Distribution patterns of tau pathology in progressive supranuclear palsy

    Authors: Gábor G. Kovács, Milica Ječmenica‐Lukić, David J. Irwin, Thomas Arzberger, Gesine Respondek, Edward B. Lee, David G. Coughlin, Armin Giese, Murray Grossman, Carolin Kurz, Corey T. McMillan, Ellen Gelpí, Yaroslau Compta, John C. van Swieten, Laura Donker Laat, Claire Troakes, Safa Al‐Sarraj, John Robinson, Sigrun Roeber, Sharon X. Xie, Virginia M.‐Y. Lee, John Q. Trojanowski, Günter U. Höglinger - Acta Neuropathologica 2020 cited by 471

  8. Neuropathological and genetic correlates of survival and dementia onset in synucleinopathies: a retrospective analysis

    Authors: David J. Irwin, Murray Grossman, Daniel Weintraub, Howard I. Hurtig, John E. Duda, Sharon X. Xie, Edward B. Lee, Vivianna M. Van Deerlin, Oscar L. López, Julia Kofler, Peter T. Nelson, Gregory A. Jicha, Randy Woltjer, Joseph F. Quinn, Jeffrey Kaye, James B. Leverenz, Debby W. Tsuang, Katelan Longfellow, Dora Yearout, Walter A. Kukull, C. Dirk Keene, Thomas J. Montine, Cyrus P. Zabetian, John Q. Trojanowski - The Lancet Neurology 2016 cited by 591

  9. Stages of pTDP‐43 pathology in amyotrophic lateral sclerosis

    Authors: Johannes Brettschneider, Kelly Del Tredici, Jon B. Toledo, John Robinson, David J. Irwin, Murray Grossman, EunRan Suh, Vivianna M. Van Deerlin, Elisabeth McCarty Wood, Young Min Baek, Linda K. Kwong, Edward B. Lee, Lauren Elman, Leo McCluskey, Lubin Fang, Simone Feldengut, Albert C. Ludolph, Virginia M.‐Y. Lee, Heiko Braak, John Q. Trojanowski - Annals of Neurology 2013 cited by 1,066

  10. Postmortem Cortex Samples Identify Distinct Molecular Subtypes of ALS: Retrotransposon Activation, Oxidative Stress, and Activated Glia

    Authors: Oliver H. Tam, Nikolay V. Rozhkov, Regina Shaw, Duyang Kim, Isabel Hubbard, Samantha Fennessey, Nadia Propp, Hemali Phatnani, Justin Kwan, Dhruv Sareen, James R. Broach, Zachary Simmons, Ximena Arcila-Londono, Edward B. Lee, Vivianna M. Van Deerlin, Neil A. Shneider, Ernest Fraenkel, Lyle W. Ostrow, Frank Baas, Noah Zaitlen, James D. Berry, Andrea Malaspina, Pietro Fratta, Gregory A. Cox, Leslie M. Thompson, Steven Finkbeiner, Efthimios Dardiotis, Jonathan Mill, Siddharthan Chandran, Suvankar Pal, Eran Hornstein, Daniel J. MacGowan, Terry Heiman‐Patterson, Molly Hammell, Nikolaos A. Patsopoulos, Oleg Butovsky, Josh Dubnau, Avindra Nath, Robert Bowser, Matt Harms, Eleonora Aronica, Mary Poss, Jennifer E. Phillips‐Cremins, John F. Crary, Nazem Atassi, Dale J. Lange, Darius J. Adams, Leonidas Stefanis, Marc Gotkine, Robert W. Baloh, Suma Babu, Towfique Raj, Sabrina Paganoni, Ophir Shalem, Colin Smith, Bin Zhang, Brent T. Harris, Delphine Fagegaltier, Brent T. Harris, Lyle W. Ostrow, Hemali Phatnani, John Ravits, Josh Dubnau, Molly Hammell - Cell Reports 2019 cited by 333

  11. Loss of Nuclear TDP-43 Is Associated with Decondensation of LINE Retrotransposons

    Authors: Elaine Y. Liu, Jenny Russ, Christopher P. Cali, Jessica M. Phan, Alexandre Amlie‐Wolf, Edward B. Lee - Cell Reports 2019 cited by 246

  12. LATE-NC staging in routine neuropathologic diagnosis: an update

    Authors: Peter T. Nelson, Edward B. Lee, Matthew D. Cykowski, Irina Alafuzoff, Konstantinos Arfanakis, Johannes Attems, Carol Brayne, María M. Corrada, Brittany N. Dugger, Margaret E. Flanagan, Bernardino Ghetti, Lea T. Grinberg, Murray Grossman, Michel J. Grothe, Glenda M. Halliday, Masato Hasegawa, Suvi R. K. Hokkanen, Sally Hunter, K. A. Jellinger, Claudia H. Kawas, C. Dirk Keene, Naomi Kouri, Gábor G. Kovács, James B. Leverenz, Caitlin S. Latimer, Ian R. Mackenzie, Qinwen Mao, Kirsty E. McAleese, Richard L. Merrick, Thomas J. Montine, Melissa E. Murray, Liisa Myllykangas, Sukriti Nag, Janna H. Neltner, Kathy L. Newell, Robert A. Rissman, Yuko Saito, S. Ahmad Sajjadi, Katherine E. Schwetye, Andrew F. Teich, Dietmar Rudolf Thal, Sandra O. Tomé, Juan C. Troncoso, Shih‐Hsiu J. Wang, Charles L. White, Thomas Wısnıewskı, Hyun‐Sik Yang, Julie A. Schneider, Dennis W. Dickson, Manuela Neumann - Acta Neuropathologica 2022 cited by 176

  13. Aging-related tau astrogliopathy (ARTAG): harmonized evaluation strategy

    Authors: Gábor G. Kovács, Isidró Ferrer, Lea T. Grinberg, Irina Alafuzoff, Johannes Attems, Herbert Budka, Nigel J. Cairns, John F. Crary, Charles Duyckaerts, Bernardino Ghetti, Glenda M. Halliday, James W. Ironside, Seth Love, Ian R. Mackenzie, David G. Muñoz, Melissa E. Murray, Peter T. Nelson, Hitoshi Takahashi, John Q. Trojanowski, Olaf Ansorge, Thomas Arzberger, Atik Baborie, Thomas G. Beach, Kevin F. Bieniek, Eileen H. Bigio, István Bódi, Brittany N. Dugger, Mel Β. Feany, Ellen Gelpí, Stephen M. Gentleman, Giorgio Giaccone, Kimmo J. Hatanpaa, Richard Heale, Patrick R. Hof, Monika Hofer, Tibor Hortobágyi, K. A. Jellinger, Gregory A. Jicha, Paul G. Ince, Julia Kofler, Enikò Kövari, Jillian J. Kril, David Mann, Radoslav Matěj, Ann C. McKee, Catriona McLean, Ivan Milenković, Thomas J. Montine, Shigeo Murayama, Edward B. Lee, Jasmin Rahimi, Roberta Diehl Rodriguez, Annemieke J.M. Rozemüller, Julie A. Schneider, Christian Schultz, William W. Seeley, Danielle Seilhean, Colin Smith, Fabrizio Tagliavini, Masaki Takao, Dietmar Rudolf Thal, Jon B. Toledo, Markus Tolnay, Juan C. Troncoso, Harry V. Vinters, Serge Weis, Stephen B. Wharton, Charles L. White, Thomas Wısnıewskı, John Woulfe, Masahito Yamada, Dennis W. Dickson - Acta Neuropathologica 2015 cited by 530

  14. Phosphorylation of S409/410 of TDP-43 is a consistent feature in all sporadic and familial forms of TDP-43 proteinopathies

    Authors: Manuela Neumann, Linda K. Kwong, Edward B. Lee, Elisabeth Kremmer, Andrew Flatley, Yan Xu, Mark S. Forman, Dirk Troost, Hans A. Kretzschmar, John Q. Trojanowski, Virginia M.‐Y. Lee - Acta Neuropathologica 2009 cited by 610

  15. Gasdermin-E mediates mitochondrial damage in axons and neurodegeneration

    Authors: Dylan V. Neel, Himanish Basu, Georgia Gunner, Matthew Bergstresser, Richard M. Giadone, Haeji Chung, Rui Miao, Vicky Chou, Eliza M. Brody, Xin Jiang, Edward B. Lee, Michelle Watts, Christine Marques, Aaron Held, Brian J. Wainger, Clotilde Lagier‐Tourenne, Yong‐Jie Zhang, Leonard Petrucelli, Tracy L. Young‐Pearse, Alice Chen‐Plotkin, Lee L. Rubin, Judy Lieberman, Isaac M. Chiu - Neuron 2023 cited by 124

  16. Deciphering tumor ecosystems at super resolution from spatial transcriptomics with TESLA

    Authors: Jian Hu, Kyle Coleman, Daiwei Zhang, Edward B. Lee, Humam Kadara, Linghua Wang, Mingyao Li - Cell Systems 2023 cited by 95

  17. APOE and TREM2 regulate amyloid-responsive microglia in Alzheimer’s disease

    Authors: Aivi T. Nguyen, Kui Wang, Gang Hu, Xuran Wang, Zhen Miao, Joshua A. Azevedo, EunRan Suh, Vivianna M. Van Deerlin, David Choi, Kathryn Roeder, Mingyao Li, Edward B. Lee - Acta Neuropathologica 2020 cited by 281

  18. The development and convergence of co-pathologies in Alzheimer’s disease

    Authors: John Robinson, Hayley Richardson, Sharon X. Xie, EunRan Suh, Vivianna M. Van Deerlin, Brian Alfaro, Nicholas Loh, Matias Porras-Paniagua, Jeffrey Nirschl, David A. Wolk, Virginia M.‐Y. Lee, Edward B. Lee, John Q. Trojanowski - Brain 2020 cited by 203

  19. Pathological combinations in neurodegenerative disease are heterogeneous and disease-associated

    Authors: John Robinson, Sharon X. Xie, Daniel R. Baer, EunRan Suh, Vivianna M. Van Deerlin, Nicholas Loh, David J. Irwin, Corey T. McMillan, David A. Wolk, Alice Chen‐Plotkin, Daniel Weintraub, Theresa Schuck, Virginia M.‐Y. Lee, John Q. Trojanowski, Edward B. Lee - Brain 2023 cited by 166

  20. Tau deposition patterns are associated with functional connectivity in primary tauopathies

    Authors: Nicolai Franzmeier, Matthias Brendel, Leonie Beyer, Luna Slemann, Gábor G. Kovács, Thomas Arzberger, Carolin Kurz, Gesine Respondek, Milica Ječmenica‐Lukić, Davina Biel, Anna Rubinski, Lukas Frontzkowski, Selina Hummel, André Müller, Anika Finze, Carla Palleis, Emanuel Joseph, Endy Weidinger, Sabrina Katzdobler, Mengmeng Song, Gloria Biechele, Maike Kern, Maximilian Scheifele, Boris‐Stephan Rauchmann, Robert Perneczky, Michael Rullman, Marianne Patt, Andreas Schildan, Henryk Barthel, Osama Sabri, Jost J. Rumpf, Matthias L. Schroeter, Joseph Claßen, Victor L. Villemagne, John Seibyl, Andrew Stephens, Edward B. Lee, David G. Coughlin, Armin Giese, Murray Grossman, Corey T. McMillan, Ellen Gelpí, Laura Molina‐Porcel, Yaroslau Compta, John C. van Swieten, Laura Donker Laat, Claire Troakes, Safa Al‐Sarraj, John Robinson, Sharon X. Xie, David J. Irwin, Sigrun Roeber, Jochen Herms, Mikael Simons, Peter Bartenstein, Virginia M. Lee, John Q. Trojanowski, Johannes Levin, Günter U. Höglinger, Michael Ewers - Nature Communications 2022 cited by 108

  21. Rainwater Charitable Foundation criteria for the neuropathologic diagnosis of progressive supranuclear palsy

    Authors: Shanu F. Roemer, Lea T. Grinberg, John F. Crary, William W. Seeley, Ann C. McKee, Gábor G. Kovács, Thomas G. Beach, Charles Duyckaerts, Isidro A. Ferrer, Ellen Gelpí, Edward B. Lee, Tamás Révész, Charles L. White, Mari Yoshida, Felipe Luiz Pereira, Kristen Whitney, Nikhil B Ghayal, Dennis W. Dickson - Acta Neuropathologica 2022 cited by 134

  22. GPNMB confers risk for Parkinson’s disease through interaction with α-synuclein

    Authors: Maria E. Diaz‐Ortiz, Yunji Seo, Marijan Posavi, Marc Carceles Cordon, Elisia Clark, Nimansha Jain, Rakshita A. Charan, Michael D. Gallagher, Travis L. Unger, Noor Amari, R. Tyler Skrinak, Roseanne Davila‐Rivera, Eliza M. Brody, Noah Han, Rebecca Zack, Vivianna M. Van Deerlin, Thomas F. Tropea, Kelvin C. Luk, Edward B. Lee, Daniel Weintraub, Alice Chen‐Plotkin - Science 2022 cited by 152

  23. Gains or losses: molecular mechanisms of TDP43-mediated neurodegeneration

    Authors: Edward B. Lee, Virginia M.‐Y. Lee, John Q. Trojanowski - Nature reviews. Neuroscience 2011 cited by 664

  24. Patient-derived frontotemporal lobar degeneration brain extracts induce formation and spreading of TDP-43 pathology in vivo

    Authors: Sílvia Porta, Yan Xu, Clark R. Restrepo, Linda K. Kwong, Bin Zhang, Hannah J. Brown, Edward B. Lee, John Q. Trojanowski, Virginia M.‐Y. Lee - Nature Communications 2018 cited by 254