Christopher M. Sassetti
Active 1995–2025
- Also published as
- Christopher M Sassetti
- 86
- Papers
- 18,109
- Citations
- 58
- h-index
- 82
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Medicine49.8%
- Biochemistry, Genetics and Molecular Biology31.8%
- Immunology and Microbiology10.8%
- Environmental Science1.9%
- Agricultural and Biological Sciences1.4%
- Nursing0.7%
- Other3.6%
Topics
- Tuberculosis Research and Epidemiology14.9%
- Mycobacterium research and diagnosis9%
- Bacterial Genetics and Biotechnology3.4%
- Antibiotic Resistance in Bacteria3.3%
- Biochemical and Molecular Research2.9%
- RNA and protein synthesis mechanisms2.7%
- Other63.8%
Coauthors
- Eric J. Rubin18
- Kadamba Papavinasasundaram18
- Thomas R. Ioerger15
- Christina E. Baer11
- Clare M. Smith11
- Kenan C. Murphy11
- Sarah M. Fortune11
- Amit Kumar Pandey9
- Megan K. Proulx9
- Andrew J. Olive8
- Jarukit E. Long8
- Richard E. Baker8
- Samuel M. Behar8
- Bibhuti B. Mishra6
- Dirk Schnappinger6
- Michael A. DeJesus6
- Eleni Jaecklein5
- Hardy Kornfeld5
- Cara C. Boutte4
- David R. Sherman4
- James C. Sacchettini4
- Michael C Kiritsy4
- Michelle M. Bellerose4
- Scott A. Shaffer4
All papers
- Programmable transcriptional repression in mycobacteria using an orthogonal CRISPR interference platform
Authors: Jeremy M. Rock, Forrest Hopkins, Alejandro Chavez, Marieme Diallo, Michael R. Chase, Elias R. Gerrick, Justin R. Pritchard, George M. Church, Eric J. Rubin, Christopher M. Sassetti, Dirk Schnappinger, Sarah M. Fortune - Nature Microbiology 2017 cited by 576
- M. tuberculosis Reprograms Hematopoietic Stem Cells to Limit Myelopoiesis and Impair Trained Immunity
Authors: Nargis Khan, Jeffrey Downey, Joaquín Sanz, Eva Kaufmann, Birte Blankenhaus, Alain Pacis, Erwan Pernet, Eisha Ahmed, Sílvia Cardoso, Anastasia Nijnik, Bruce Mazer, Christopher M. Sassetti, Marcel A. Behr, Miguel P. Soares, Luis B. Barreiro, Maziar Divangahi - Cell 2020 cited by 289
- Comprehensive Essentiality Analysis of the Mycobacterium tuberculosis Genome via Saturating Transposon Mutagenesis
Authors: Michael A. DeJesus, Elias R. Gerrick, Weizhen Xu, Sae Woong Park, Jarukit E. Long, Cara C. Boutte, Eric J. Rubin, Dirk Schnappinger, Sabine Ehrt, Sarah M. Fortune, Christopher M. Sassetti, Thomas R. Ioerger - mBio 2017 cited by 729
- Mycobacterial persistence requires the utilization of host cholesterol
Authors: Amit Kumar Pandey, Christopher M. Sassetti - National Academy of Sciences, Proceedings of the National Academy of Sciences 2008 cited by 1,086
- Genes required for mycobacterial growth defined by high density mutagenesis
Authors: Christopher M. Sassetti, Dana Boyd, Eric J. Rubin - Molecular Microbiology 2003 cited by 2,583
- High-Resolution Phenotypic Profiling Defines Genes Essential for Mycobacterial Growth and Cholesterol Catabolism
Authors: Jennifer E. Griffin, Jeffrey D. Gawronski, Michael A. DeJesus, Thomas R. Ioerger, Brian J. Akerley, Christopher M. Sassetti - PLoS Pathogens 2011 cited by 1,089
- Nitric oxide controls the immunopathology of tuberculosis by inhibiting NLRP3 inflammasome–dependent processing of IL-1β
Authors: Bibhuti B. Mishra, Vijay Rathinam, Gregory W. Martens, Amanda J. Martinot, Hardy Kornfeld, Katherine A. Fitzgerald, Christopher M. Sassetti - Nature Immunology 2012 cited by 563
- Nitric oxide prevents a pathogen-permissive granulocytic inflammation during tuberculosis
Authors: Bibhuti B. Mishra, Rustin R. Lovewell, Andrew J. Olive, Guoliang Zhang, Wenfei Wang, Eliseo A. Eugenín, Clare M. Smith, Jia Yao Phuah, Jarukit E. Long, Michelle L. Dubuke, Samantha G. Palace, Jon D. Goguen, Richard E. Baker, Subhalaxmi Nambi, Rabinarayan Mishra, Matthew G. Booty, Christina E. Baer, Scott A. Shaffer, Véronique Dartois, Beth A. McCormick, Xinchun Chen, Christopher M. Sassetti - Nature Microbiology 2017 cited by 299
- Mycobacterium tuberculosis is protected from NADPH oxidase and LC3-associated phagocytosis by the LCP protein CpsA
Authors: Stefan Köster, Sandeep Upadhyay, Pallavi Chandra, Kadamba Papavinasasundaram, Guozhe Yang, Amir Hassan, Steven J. Grigsby, Ekansh Mittal, Heidi S. Park, Victoria Jones, Fong‐Fu Hsu, Mary Jackson, Christopher M. Sassetti, Jennifer A. Philips - National Academy of Sciences, Proceedings of the National Academy of Sciences 2017 cited by 199
- TRANSIT - A Software Tool for Himar1 TnSeq Analysis
Authors: Michael A. DeJesus, Chaitra Ambadipudi, Richard Baker, Christopher M. Sassetti, Thomas R. Ioerger - PLoS Computational Biology, PLoS Comput. Biol. 2015 cited by 293
- The Normalcy of Dormancy: Common Themes in Microbial Quiescence
Authors: Emily S. C. Rittershaus, Seung-Hun Baek, Christopher M. Sassetti - Cell Host & Microbe 2013 cited by 351
- ORBIT: a New Paradigm for Genetic Engineering of Mycobacterial Chromosomes
Authors: Kenan C. Murphy, Samantha J. Nelson, Subhalaxmi Nambi, Kadamba Papavinasasundaram, Christina E. Baer, Christopher M. Sassetti - mBio 2018 cited by 180
- CD11cHi monocyte-derived macrophages are a major cellular compartment infected by Mycobacterium tuberculosis
Authors: Jinhee Lee, Shayla Boyce, Jennifer Powers, Christina E. Baer, Christopher M. Sassetti, Samuel M. Behar - PLoS Pathogens 2020 cited by 81
- Metabolic crosstalk between host and pathogen: sensing, adapting and competing
Authors: Andrew J. Olive, Christopher M. Sassetti - Nature Reviews Microbiology 2016 cited by 234
- Granulocytes act as a niche for Mycobacterium tuberculosis growth
Authors: Rustin R. Lovewell, Christina E. Baer, Bibhuti B. Mishra, Clare M. Smith, Christopher M. Sassetti - Mucosal Immunology 2020 cited by 109
- Large-scale chemical–genetics yields new M. tuberculosis inhibitor classes
Authors: Eachan O. Johnson, Emily LaVerriere, Emma Office, Mary Stanley, Elisabeth Meyer, Tomohiko Kawate, James Gomez, Rebecca E. Audette, Nirmalya Bandyopadhyay, Natalia Betancourt, Kayla Delano, Israel Da Silva, Joshua S. Davis, Christina M. Gallo, Michelle Gardner, Aaron Golas, Kristine M. Guinn, Sofia Kennedy, Rebecca Korn, Jennifer A. McConnell, Caitlin E. Moss, Kenan C. Murphy, Raymond Nietupski, Kadamba Papavinasasundaram, Jessica T. Pinkham, Paula A. Pino, Megan K. Proulx, Nadine Ruecker, Naomi Song, Matthew P. Thompson, Carolina Trujillo, Shoko Wakabayashi, Joshua B. Wallach, Christopher Watson, Thomas R. Ioerger, Eric S. Lander, Brian K. Hubbard, Michael H. Serrano‐Wu, Sabine Ehrt, Michael G. FitzGerald, Eric J. Rubin, Christopher M. Sassetti, Dirk Schnappinger, Deborah T. Hung - Nature 2019 cited by 178
- Genetic requirements for mycobacterial survival during infection
Authors: Christopher M. Sassetti, Eric J. Rubin - National Academy of Sciences, Proceedings of the National Academy of Sciences 2003 cited by 1,405
- Metabolic Regulation of Mycobacterial Growth and Antibiotic Sensitivity
Authors: Seung-Hun Baek, Alice H. Li, Christopher M. Sassetti - PLoS Biology 2011 cited by 328
- Tuberculosis Susceptibility and Vaccine Protection Are Independently Controlled by Host Genotype
Authors: Clare M. Smith, Megan K. Proulx, Andrew J. Olive, Dominick J. Laddy, Bibhuti B. Mishra, Caitlin E. Moss, Nuria Martinez Gutierrez, Michelle M. Bellerose, Palmira Barreira‐Silva, Jia Yao Phuah, Richard E. Baker, Samuel M. Behar, Hardy Kornfeld, Thomas G. Evans, Gillian Beamer, Christopher M. Sassetti - mBio 2016 cited by 170
- The Oxidative Stress Network of Mycobacterium tuberculosis Reveals Coordination between Radical Detoxification Systems
Authors: Subhalaxmi Nambi, Jarukit E. Long, Bibhuti B. Mishra, Richard Baker, Kenan C. Murphy, Andrew J. Olive, Hien P. Nguyen, Scott A. Shaffer, Christopher M. Sassetti - Cell Host & Microbe 2015 cited by 190
- Host genetic background is a barrier to broadly effective vaccine–mediated protection against tuberculosis
Authors: Rocky Lai, Diana Gong, Travis Williams, Abiola F. Ogunsola, Kelly Cavallo, Cecilia S. Lindestam Arlehamn, Sarah Acolatse, Gillian Beamer, Martin T. Ferris, Christopher M. Sassetti, Douglas A. Lauffenburger, Samuel M. Behar - Journal of Clinical Investigation 2023 cited by 37
- Mutually dependent secretion of proteins required for mycobacterial virulence
Authors: Sarah M. Fortune, Amy Jaeger, David Sarracino, Michael R. Chase, Christopher M. Sassetti, David R. Sherman, Barry R. Bloom, Eric J. Rubin - National Academy of Sciences, Proceedings of the National Academy of Sciences 2005 cited by 410
- Cholesterol Catabolism by Mycobacterium tuberculosis Requires Transcriptional and Metabolic Adaptations
Authors: Jennifer E. Griffin, Amit Kumar Pandey, Sarah A. Gilmore, Valerie Mizrahi, John D. McKinney, Carolyn R. Bertozzi, Christopher M. Sassetti - Chemistry & Biology 2012 cited by 308
- The structure of the endogenous ESX-3 secretion system
Authors: Nicole Poweleit, Nadine Czudnochowski, Rachel Nakagawa, Donovan Trinidad, Kenan C. Murphy, Christopher M. Sassetti, Oren S. Rosenberg - eLife 2019 cited by 90
