David A. Brenner
Active 1980–2025
- 280
- Papers
- 71,658
- Citations
- 149
- h-index
- 279
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Medicine58.2%
- Biochemistry, Genetics and Molecular Biology27.7%
- Immunology and Microbiology4.9%
- Neuroscience3.4%
- Pharmacology, Toxicology and Pharmaceutics1.6%
- Nursing1%
- Other3.2%
Topics
- Liver Disease Diagnosis and Treatment11%
- Liver physiology and pathology5%
- Gut microbiota and health3.6%
- Liver Disease and Transplantation2.5%
- Alcohol Consumption and Health Effects2.1%
- Diet, Metabolism, and Disease1.9%
- Other73.9%
Coauthors
- Tatiana Kisseleva68
- Bernd Schnabl39
- Rohit Loomba36
- Ekihiro Seki29
- Xiao Liu29
- Robert F. Schwabe23
- Ramón Bataller21
- Claude B. Sirlin19
- Michael Karin17
- Richard A. Rippe17
- Keiko Iwaisako16
- Samuele De Minicis16
- Yong‐Han Paik16
- Yukinori Koyama14
- Cynthia A. Bradham13
- John J. Lemasters13
- Jun Xu13
- Ricki Bettencourt13
- Kojiro Taura12
- Yuzo Kodama12
- Christoph H. Österreicher11
- Claus Hellerbrand11
- Lisa Richards11
- Sara Brin Rosenthal11
All papers
- Molecular and cellular mechanisms of liver fibrosis and its regression
Authors: Tatiana Kisseleva, David A. Brenner - Nature Reviews Gastroenterology & Hepatology 2020 cited by 1,918
- The gut–liver axis and the intersection with the microbiome
Authors: Anupriya Tripathi, Justine W. Debelius, David A. Brenner, Michael Karin, Rohit Loomba, Bernd Schnabl, Rob Knight - Nature Reviews Gastroenterology & Hepatology 2018 cited by 1,424
- Gut Microbiome-Based Metagenomic Signature for Non-invasive Detection of Advanced Fibrosis in Human Nonalcoholic Fatty Liver Disease
Authors: Rohit Loomba, Victor Seguritan, Weizhong Li, Tao Long, Niels Klitgord, Archana Bhatt, Parambir S. Dulai, Cyrielle Caussy, Richele Bettencourt, Sarah K. Highlander, Marcus B. Jones, Claude B. Sirlin, Bernd Schnabl, Lauren Brinkac, Nicholas J. Schork, Chi‐Hua Chen, David A. Brenner, William Biggs, Shibu Yooseph, J. Craig Venter, Karen E. Nelson - Cell Metabolism 2017 cited by 1,097
- Liver inflammation and fibrosis
Authors: Yukinori Koyama, David A. Brenner - Journal of Clinical Investigation 2017 cited by 1,275
- Wastewater sequencing reveals early cryptic SARS-CoV-2 variant transmission
Authors: Smruthi Karthikeyan, Joshua I. Levy, Peter De Hoff, Greg Humphrey, Amanda Birmingham, Kristen Jepsen, Sawyer Farmer, Helena M. Tubb, Tommy Valles, Caitlin Tribelhorn, Rebecca Tsai, Stefan Aigner, Shashank Sathe, Niema Moshiri, Benjamin Henson, Adam M. Mark, Abbas Hakim, Nathan A. Baer, Tom Barber, Pedro Belda‐Ferre, Marisol Chacón, Willi Cheung, Evelyn S. Cresini, Emily Eisner, Alma L. Lastrella, Elijah S. Lawrence, Clarisse Marotz, Toan T. Ngo, Tyler Ostrander, Ashley Plascencia, Rodolfo A. Salido, Phoebe Seaver, Elizabeth W. Smoot, Daniel McDonald, Robert M. Neuhard, Angela L. Scioscia, Alysson M. Satterlund, Elizabeth H. Simmons, Dismas B. Abelman, David A. Brenner, Judith C. Bruner, Anne F. Buckley, M. Ellison, Jeffrey Gattas, Steven L. Gonias, Matt Hale, Faith Hawkins, Lydia Ikeda, Hemlata Jhaveri, Ted W. Johnson, Vince Kellen, Brendan Kremer, Gary Matthews, Ronald W. McLawhon, Pierre Ouillet, Daniel Park, Allorah Pradenas, Sharon L. Reed, Lindsay Riggs, Alison Sanders, Bradley Sollenberger, Angela Song, Benjamin L. White, Terri Winbush, Christine M. Aceves, Catelyn Anderson, Karthik Gangavarapu, Emory Hufbauer, Ezra Kurzban, Justin Lee, Nathaniel L. Matteson, Edyth Parker, Sarah A. Perkins, Karthik Ramesh, Refugio Robles‐Sikisaka, Madison Schwab, Emily Spencer, Shirlee Wohl, Laura Nicholson, Ian McHardy, David Dimmock, Charlotte A. Hobbs, Omid Bakhtar, Aaron Harding, Art Mendoza, Alexandre Bolze, David G. Becker, Elizabeth T. Cirulli, Magnus Isaksson, Kelly M. Schiabor Barrett, Nicole Washington, John D. Malone, Ashleigh Murphy Schafer, Nikos Gurfield, Sarah Stous, Rebecca Fielding‐Miller, Richard S. Garfein, Tommi Gaines, Cheryl A.M. Anderson, Natasha K. Martin and 18 more - Nature 2022 cited by 520
- TLR4 enhances TGF-β signaling and hepatic fibrosis
Authors: Ekihiro Seki, Samuele De Minicis, Christoph H. Österreicher, Johannes Kluwe, Yosuke Osawa, David A. Brenner, Robert F. Schwabe - Nature Medicine 2007 cited by 1,910
- Mechanisms of liver fibrosis and its role in liver cancer
Authors: Debanjan Dhar, Jacopo Baglieri, Tatiana Kisseleva, David A. Brenner - Experimental Biology and Medicine 2020 cited by 441
- Aberrant iron distribution via hepatocyte-stellate cell axis drives liver lipogenesis and fibrosis
Authors: Hong Gao, Zhongmou Jin, Gautam Bandyopadhyay, Gaowei Wang, Dinghong Zhang, Karina Cunha e Rocha, Xiao Liu, Huayi Zhao, Tatiana Kisseleva, David A. Brenner, Michael Karin, Wei Ying - Cell Metabolism 2022 cited by 210
- Magnetic Resonance Elastography vs Transient Elastography in Detection of Fibrosis and Noninvasive Measurement of Steatosis in Patients With Biopsy-Proven Nonalcoholic Fatty Liver Disease
Authors: Charlie C. Park, Phirum Nguyen, Carolyn Hernandez, Ricki Bettencourt, Kimberly Ramirez, Lynda Fortney, Jonathan Hooker, Ethan Sy, Michael T. Savides, Mosab H. Alquiraish, Mark A. Valasek, Emily Rizo, Lisa Richards, David A. Brenner, Claude B. Sirlin, Rohit Loomba - Gastroenterology 2016 cited by 697
- Interactions Between the Intestinal Microbiome and Liver Diseases
Authors: Bernd Schnabl, David A. Brenner - Gastroenterology 2014 cited by 973
- Collagenolysis-dependent DDR1 signalling dictates pancreatic cancer outcome
Authors: Hua Su, Fei Yang, Rao Fu, Brittney Trinh, Nina Sun, Junlai Liu, Avi Kumar, Jacopo Baglieri, Jeremy Siruno, Michelle Le, Yuhan Li, Stephen Dozier, Ajay Nair, Aveline Filliol, Nachanok Sinchai, Sara Brin Rosenthal, Jennifer Santini, Christian M. Metallo, Anthony Molina, Robert F. Schwabe, Andrew M. Lowy, David A. Brenner, Beicheng Sun, Michael Karin - Nature 2022 cited by 241
- A Universal Gut-Microbiome-Derived Signature Predicts Cirrhosis
Authors: Tae Gyu Oh, Susy M. Kim, Cyrielle Caussy, Ting Fu, Jian Guo, Shirin Bassirian, Seema Singh, Egbert Madamba, Ricki Bettencourt, Lisa Richards, Ruth T. Yu, Annette R. Atkins, Tao Huan, David A. Brenner, Claude B. Sirlin, Michael Downes, Ronald M. Evans, Rohit Loomba - Cell Metabolism 2020 cited by 336
- Myofibroblasts revert to an inactive phenotype during regression of liver fibrosis
Authors: Tatiana Kisseleva, Min Cong, Yong‐Han Paik, David Scholten, Chunyan Jiang, Christopher Benner, Keiko Iwaisako, Thomas Moore‐Morris, Brian T. Scott, Hidekazu Tsukamoto, Sylvia Μ. Evans, Wolfgang Dillmann, Christopher K. Glass, David A. Brenner - National Academy of Sciences, Proceedings of the National Academy of Sciences 2012 cited by 788
- Enteric dysbiosis associated with a mouse model of alcoholic liver disease
Authors: Arthur W. Yan, Derrick E. Fouts, Johannes Brandl, Peter Stärkel, Manolito Torralba, Eckart Schott, Hide Tsukamoto, Karen E. Nelson, David A. Brenner, Bernd Schnabl - Hepatology 2010 cited by 780
- Intestinal FXR agonism promotes adipose tissue browning and reduces obesity and insulin resistance
Authors: Sungsoon Fang, Jae Myoung Suh, Shannon M. Reilly, Elizabeth L. Yu, Olivia Osborn, Denise E. Lackey, Eiji Yoshihara, Alessia Perino, Sandra Jacinto, Yelizaveta Lukasheva, Annette R. Atkins, Alexander Khvat, Bernd Schnabl, Ruth T. Yu, David A. Brenner, Sally Coulter, Christopher Liddle, Kristina Schoonjans, Jerrold M. Olefsky, Alan R. Saltiel, Michael Downes, Ronald M. Evans - Nature Medicine 2015 cited by 711
- The Role of Fibrosis and Liver-Associated Fibroblasts in the Pathogenesis of Hepatocellular Carcinoma
Authors: Jacopo Baglieri, David A. Brenner, Tatiana Kisseleva - International Journal of Molecular Sciences 2019 cited by 348
- Interleukin-17 Signaling in Inflammatory, Kupffer Cells, and Hepatic Stellate Cells Exacerbates Liver Fibrosis in Mice
Authors: Fanli Meng, Kai Wang, Tomonori Aoyama, Sergei I. Grivennikov, Yong‐Han Paik, David Scholten, Min Cong, Keiko Iwaisako, Xiao Liu, Mingjun Zhang, Christoph H. Österreicher, Felix Stickel, Klaus Ley, David A. Brenner, Tatiana Kisseleva - Gastroenterology 2012 cited by 697
- Toll-Like Receptor 9 Promotes Steatohepatitis by Induction of Interleukin-1β in Mice
Authors: Kouichi Miura, Yuzo Kodama, Sayaka Inokuchi, Bernd Schnabl, Tomonori Aoyama, Hirohide Ohnishi, Jerrold M. Olefsky, David A. Brenner, Ekihiro Seki - Gastroenterology 2010 cited by 731
- Resident fibroblast lineages mediate pressure overload–induced cardiac fibrosis
Authors: Thomas Moore‐Morris, Nuno Guimarães‐Camboa, Indroneal Banerjee, Alexander C. Zambon, Tatiana Kisseleva, Aurélie Velayoudon, William B. Stallcup, Yusu Gu, Nancy D. Dalton, Marta Cedenilla, Rafael L Gomez-Amaro, Bin Zhou, David A. Brenner, Kirk L. Peterson, Chen Ju, Sylvia Μ. Evans - Journal of Clinical Investigation 2014 cited by 621
- A gut microbiome signature for cirrhosis due to nonalcoholic fatty liver disease
Authors: Cyrielle Caussy, Anupriya Tripathi, Greg Humphrey, Shirin Bassirian, Seema Singh, Claire Faulkner, Ricki Bettencourt, Emily Rizo, Lisa Richards, Zhenjiang Zech Xu, Michael Downes, Ronald M. Evans, David A. Brenner, Claude B. Sirlin, Rob Knight, Rohit Loomba - Nature Communications 2019 cited by 335
- Origin of myofibroblasts in the fibrotic liver in mice
Authors: Keiko Iwaisako, Chunyan Jiang, Mingjun Zhang, Min Cong, Thomas Moore‐Morris, Tae Jun Park, Xiao Liu, Jun Xu, Ping Wang, Yong‐Han Paik, Fanli Meng, Masataka Asagiri, Lynne A. Murray, Alan F. Hofmann, Takashi Iida, Christopher K. Glass, David A. Brenner, Tatiana Kisseleva - National Academy of Sciences, Proceedings of the National Academy of Sciences 2014 cited by 535
- IL-17 signaling in steatotic hepatocytes and macrophages promotes hepatocellular carcinoma in alcohol-related liver disease
Authors: Hsiao‐Yen Ma, Gen Yamamoto, Jun Xu, Xiao Liu, Daniel Karin, Ju Youn Kim, Ludmil B. Alexandrov, Yukinori Koyama, Takahiro Nishio, Christopher Benner, Sven Heinz, Sara Brin Rosenthal, Shuang Liang, Mengxi Sun, Gabriel Karin, Peng Zhao, Pnina Brodt, Iain H. McKillop, Oswald Quehenberger, Edward A. Dennis, Alan R. Saltiel, Hidekazu Tsukamoto, Bin Gao, Michael Karin, David A. Brenner, Tatiana Kisseleva - Journal of Hepatology 2019 cited by 210
- Magnetic resonance elastography predicts advanced fibrosis in patients with nonalcoholic fatty liver disease: A prospective study
Authors: Rohit Loomba, Tanya Wolfson, Brandon Ang, Jonathan Hooker, Cynthia Behling, Michael R. Peterson, Mark A. Valasek, Grace Lin, David A. Brenner, Anthony Gamst, Richard L. Ehman, Claude B. Sirlin - Hepatology 2014 cited by 477
- Modulation of the intestinal bile acid/farnesoid X receptor/fibroblast growth factor 15 axis improves alcoholic liver disease in mice
Authors: Phillipp Hartmann, K Hochrath, Angela Horvath, Peng Chen, Caroline T. Seebauer, Cristina Llorente, Lirui Wang, Yazen Alnouti, Derrick E. Fouts, Peter Stärkel, Rohit Loomba, Sally Coulter, Christopher Liddle, Ruth T. Yu, Lei Ling, Stephen J. Rossi, Alex M. DePaoli, Michael Downes, Ronald M. Evans, David A. Brenner, Bernd Schnabl - Hepatology 2017 cited by 275
