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Alan F. Hofmann

Active 1962–2020

Also published as
ALAN F. HOFMANN
140
Papers
29,755
Citations
105
h-index
140
i10-index

Citations

Citations per year for Alan F. Hofmann1967: 29 citations1968: 45 citations1969: 38 citations1970: 29 citations1971: 34 citations1972: 74 citations1973: 112 citations1974: 103 citations1975: 115 citations1976: 104 citations1977: 105 citations1978: 88 citations1979: 57 citations1980: 66 citations1981: 87 citations1982: 103 citations1983: 95 citations1984: 90 citations1985: 53 citations1986: 78 citations1987: 45 citations1988: 51 citations1989: 86 citations1990: 55 citations1991: 42 citations1992: 72 citations1993: 61 citations1994: 53 citations1995: 65 citations1996: 60 citations1997: 60 citations1998: 80 citations1999: 136 citations2000: 122 citations2001: 140 citations2002: 113 citations2003: 142 citations2004: 114 citations2005: 103 citations2006: 144 citations2007: 118 citations2008: 206 citations2009: 209 citations2010: 215 citations2011: 119 citations2012: 121 citations2013: 182 citations2014: 208 citations2015: 158 citations2016: 146 citations2017: 156 citations2018: 176 citations2019: 466 citations2020: 496 citations2021: 521 citations2022: 426 citations2023: 246 citations2024: 411 citations2025: 169 citations2026: 6 citations

Citation sources

Countries

World map of the countries and regions citing this authorUnited States: 2,182 citing papers, 31.1% of this breakdownChina: 684 citing papers, 9.7% of this breakdownUnited Kingdom: 478 citing papers, 6.8% of this breakdownGermany: 430 citing papers, 6.1% of this breakdownNetherlands: 306 citing papers, 4.3% of this breakdownJapan: 259 citing papers, 3.7% of this breakdownItaly: 250 citing papers, 3.6% of this breakdownFrance: 237 citing papers, 3.4% of this breakdownCanada: 222 citing papers, 3.2% of this breakdownSweden: 192 citing papers, 2.7% of this breakdownSwitzerland: 189 citing papers, 2.7% of this breakdownSpain: 146 citing papers, 2.1% of this breakdown
0%31.1%Other 20.6%

Institutions

Fields

  • Medicine67%
  • Biochemistry, Genetics and Molecular Biology17.5%
  • Agricultural and Biological Sciences3.9%
  • Nursing3.1%
  • Pharmacology, Toxicology and Pharmaceutics2.8%
  • Neuroscience1.4%
  • Other4.3%

Topics

  • Drug Transport and Resistance Mechanisms13.8%
  • Liver Disease Diagnosis and Treatment6.1%
  • Pediatric Hepatobiliary Diseases and Treatments4.8%
  • Gut microbiota and health3.8%
  • Liver Diseases and Immunity3.4%
  • Diet and metabolism studies2.5%
  • Other65.6%

Coauthors

All papers

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  1. The Continuing Importance of Bile Acids in Liver and Intestinal Disease

    Authors: Alan F. Hofmann - Archives of Internal Medicine 1999 cited by 979

  2. Origin of myofibroblasts in the fibrotic liver in mice

    Authors: Keiko Iwaisako, Chunyan Jiang, Mingjun Zhang, Min Cong, Thomas Moore‐Morris, Tae Jun Park, Xiao Liu, Jun Xu, Ping Wang, Yong‐Han Paik, Fanli Meng, Masataka Asagiri, Lynne A. Murray, Alan F. Hofmann, Takashi Iida, Christopher K. Glass, David A. Brenner, Tatiana Kisseleva - National Academy of Sciences, Proceedings of the National Academy of Sciences 2014 cited by 535

  3. The bile acid TGR5 membrane receptor: From basic research to clinical application

    Authors: Henri Duboc, Yvette Taché, Alan F. Hofmann - Digestive and Liver Disease 2014 cited by 460

  4. Bile Acids: Chemistry, Pathochemistry, Biology, Pathobiology, and Therapeutics

    Authors: Alan F. Hofmann, Lee R. Hagey - Cellular and Molecular Life Sciences 2008 cited by 841

  5. Key discoveries in bile acid chemistry and biology and their clinical applications: history of the last eight decades

    Authors: Alan F. Hofmann, Lee R. Hagey - Journal of Lipid Research 2014 cited by 362

  6. Guts and Gall: Bile Acids in Regulation of Intestinal Epithelial Function in Health and Disease

    Authors: Péter Hegyi, József Maléth, Julian R.F. Walters, Alan F. Hofmann, Stephen J. Keely - Physiological Reviews 2018 cited by 264

  7. Human cecal bile acids: concentration and spectrum

    Authors: James P. Hamilton, Guofeng Xie, Jean-Pierre Raufman, Susan L. Hogan, Terrance L. Griffin, Christine A. Packard, Dale A. Chatfield, Lee R. Hagey, Joseph H. Steinbach, Alan F. Hofmann - American Journal of Physiology-Gastrointestinal and Liver Physiology 2007 cited by 268

  8. Serum bile acid patterns are associated with the presence of NAFLD in twins, and dose‐dependent changes with increase in fibrosis stage in patients with biopsy‐proven NAFLD

    Authors: Cyrielle Caussy, Cynthia L. Hsu, Seema Singh, Shirin Bassirian, James Kolar, Claire Faulkner, Nikhil Sinha, Ricki Bettencourt, Naveen Gara, Mark A. Valasek, Bernd Schnabl, Lisa Richards, David A. Brenner, Alan F. Hofmann, Rohit Loomba - Alimentary Pharmacology & Therapeutics 2018 cited by 127

  9. Bile salts of vertebrates: structural variation and possible evolutionary significance

    Authors: Alan F. Hofmann, Lee R. Hagey, Matthew D. Krasowski - Journal of Lipid Research 2009 cited by 423

  10. Novel Potent and Selective Bile Acid Derivatives as TGR5 Agonists: Biological Screening, Structure−Activity Relationships, and Molecular Modeling Studies

    Authors: Hiroyuki Sato, Antonio Macchiarulo, Charles Thomas, Antimo Gioiello, Mizuho Une, Alan F. Hofmann, Régis Saladin, Kristina Schoonjans, Roberto Pellicciari, Johan Auwerx - Journal of Medicinal Chemistry 2008 cited by 288

  11. A simple and accurate HPLC method for fecal bile acid profile in healthy and cirrhotic subjects: validation by GC-MS and LC-MS

    Authors: Genta Kakiyama, Akina Muto, Hajime Takei, Hiroshi Nittono, Tsuyoshi Murai, Takao Kurosawa, Alan F. Hofmann, William M. Pandak, Jasmohan S. Bajaj - Journal of Lipid Research 2014 cited by 132

  12. Obeticholic acid improves hepatic bile acid excretion in patients with primary biliary cholangitis

    Authors: Kristoffer Kjærgaard, Kim Frisch, Michael Sørensen, Ole Lajord Munk, Alan F. Hofmann, Jacob Horsager, Anna C. Schacht, Mary Erickson, Д. А. Шапиро, Susanne Keiding - Journal of Hepatology 2020 cited by 83

  13. Bile Acids: The Good, the Bad, and the Ugly

    Authors: Alan F. Hofmann - Physiology 1999 cited by 369

  14. 24-norUrsodeoxycholic Acid Is Superior to Ursodeoxycholic Acid in the Treatment of Sclerosing Cholangitis in Mdr2 (Abcb4) Knockout Mice

    Authors: Peter Fickert, Martin Wagner, Hanns–Ulrich Marschall, Andrea Fuchsbichler, Gernot Zollner, Oleksiy Tsybrovskyy, Kurt Zatloukal, Jie Liu, Michael P. Waalkes, Cathleen Cover, Helmut Denk, Alan F. Hofmann, Hartmut Jaeschke, Michael Trauner - Gastroenterology 2006 cited by 299

  15. Detoxification of Lithocholic Acid, A Toxic Bile Acid: Relevance to Drug Hepatotoxicity

    Authors: Alan F. Hofmann - Drug Metabolism Reviews 2004 cited by 265

  16. Chemistry and Enterohepatic Circulation of Bile Acids† ‡ § ¶ # ‖ ** †† ‡‡ §§ ¶¶ ‖‖ ##

    Authors: Alan F. Hofmann - Hepatology 1984 cited by 176

  17. Diversity of Bile Salts in Fish and Amphibians: Evolution of a Complex Biochemical Pathway

    Authors: Lee R. Hagey, Peter Möller, Alan F. Hofmann, Matthew D. Krasowski - Physiological and Biochemical Zoology 2010 cited by 151

  18. Ursodeoxycholic acid in the treatment of primary biliary cirrhosis

    Authors: Keith D. Lindor, E. Rolland Dickson, William P. Baldus, Roberta A. Jorgensen, Jürgen Ludwig, Paul A. Murtaugh, Jay M. Harrison, Russell H. Wiesner, Monte L. Anderson, Stephen M. Lange, Gene LeSage, Steven S. Rossi, Alan F. Hofmann - Gastroenterology 1994 cited by 490

  19. Bile acid solubility and precipitation in vitro and in vivo: the role of conjugation, pH, and Ca2+ ions.

    Authors: Alan F. Hofmann, Karol J. Mysels - Journal of Lipid Research 1992 cited by 285

  20. Bile salts as biological surfactants

    Authors: Alan F. Hofmann, Karol J. Mysels - Colloids and Surfaces 1987 cited by 192

  21. Enhancement of Dietary Protein Digestion by Conjugated Bile Acids

    Authors: Jonathan Gass, Harmit Vora, Alan F. Hofmann, Gary M. Gray, Chaitan Khosla - Gastroenterology 2007 cited by 144

  22. Evolution of the bile salt nuclear receptor FXR in vertebrates*

    Authors: Erica J. Reschly, Ni Ai, Sean Ekins, William J. Welsh, Lee R. Hagey, Alan F. Hofmann, Matthew D. Krasowski - Journal of Lipid Research 2008 cited by 109

  23. The Sister of P-glycoprotein Represents the Canalicular Bile Salt Export Pump of Mammalian Liver

    Authors: Thomas Gerloff, Bruno Stieger, Bruno Hagenbuch, Jerzy Madon, Lukas Landmann, Jürgen Roth, Alan F. Hofmann, Peter J. Meier - Journal of Biological Chemistry 1998 cited by 938

  24. Genetic Defects in Bile Acid Conjugation Cause Fat-Soluble Vitamin Deficiency

    Authors: Kenneth D.R. Setchell, James E. Heubi, Sohela Shah, Joel E. Lavine, David L. Suskind, Mohammed Al–Edreesi, Carol Potter, David W. Russell, Nancy C. O’Connell, Brian Wolfe, Pinky Jha, Wujuan Zhang, Kevin E. Bove, A. S. Knisely, Alan F. Hofmann, Philip Rosenthal, Laura N. Bull - Gastroenterology 2013 cited by 127