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Kenneth D.R. Setchell

Active 1976–2025

Also published as
Kenneth D R Setchell · Kenneth D. R. Setchell
145
Papers
28,151
Citations
96
h-index
143
i10-index

Citations

Citations per year for Kenneth D.R. Setchell1970: 1 citations1971: 1 citations1972: 1 citations1977: 4 citations1978: 1 citations1979: 4 citations1980: 3 citations1981: 5 citations1982: 10 citations1983: 9 citations1984: 13 citations1985: 19 citations1986: 17 citations1987: 25 citations1988: 28 citations1989: 8 citations1990: 27 citations1991: 48 citations1992: 66 citations1993: 44 citations1994: 91 citations1995: 99 citations1996: 112 citations1997: 126 citations1998: 256 citations1999: 192 citations2000: 261 citations2001: 285 citations2002: 343 citations2003: 388 citations2004: 301 citations2005: 297 citations2006: 322 citations2007: 279 citations2008: 262 citations2009: 279 citations2010: 291 citations2011: 187 citations2012: 156 citations2013: 172 citations2014: 138 citations2015: 168 citations2016: 174 citations2017: 143 citations2018: 169 citations2019: 450 citations2020: 494 citations2021: 500 citations2022: 384 citations2023: 265 citations2024: 438 citations2025: 226 citations2026: 2 citations1973–1976: no citations, so these years are not shown

Citation sources

Countries

World map of the countries and regions citing this authorUnited States: 2,330 citing papers, 30.1% of this breakdownChina: 593 citing papers, 7.7% of this breakdownUnited Kingdom: 527 citing papers, 6.8% of this breakdownGermany: 324 citing papers, 4.2% of this breakdownItaly: 297 citing papers, 3.8% of this breakdownCanada: 268 citing papers, 3.5% of this breakdownJapan: 263 citing papers, 3.4% of this breakdownNetherlands: 249 citing papers, 3.2% of this breakdownFrance: 246 citing papers, 3.2% of this breakdownSpain: 198 citing papers, 2.6% of this breakdownAustralia: 174 citing papers, 2.3% of this breakdownSweden: 173 citing papers, 2.2% of this breakdown
0%30.1%Other 27%

Institutions

Fields

  • Medicine70.9%
  • Biochemistry, Genetics and Molecular Biology16.1%
  • Nursing3.4%
  • Agricultural and Biological Sciences2.5%
  • Neuroscience1.5%
  • Pharmacology, Toxicology and Pharmaceutics1.5%
  • Other4.1%

Topics

  • Phytoestrogen effects and research11.2%
  • Drug Transport and Resistance Mechanisms5.7%
  • Estrogen and related hormone effects3.3%
  • Pediatric Hepatobiliary Diseases and Treatments2.5%
  • Phytochemicals and Antioxidant Activities2.4%
  • Liver Disease Diagnosis and Treatment2.3%
  • Other72.6%

Coauthors

All papers

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  1. Efficacy and safety of maralixibat treatment in patients with Alagille syndrome and cholestatic pruritus (ICONIC): a randomised phase 2 study

    Authors: Emmanuel Gonzalès, Winita Hardikar, Michael Stormon, Alastair Baker, Loreto Hierro, Dorota Gliwicz, Florence Lacaille, Alain Lachaux, Ekkehard Sturm, Kenneth D.R. Setchell, Ciara Kennedy, Alejandro Dorenbaum, Jana I. Steinmetz, Nirav K. Desai, Andrew J Wardle, Will Garner, Pamela Vig, Thomas Jaecklin, Étienne Sokal, Emmanuel Jacquemin - The Lancet 2021 cited by 169

  2. Inhibition of ileal bile acid uptake protects against nonalcoholic fatty liver disease in high-fat diet–fed mice

    Authors: Anuradha Rao, Astrid Kosters, Jamie E. Mells, Wujuan Zhang, Kenneth D.R. Setchell, Angélica M. Amanso, Grace M. Wynn, Tianlei Xu, Brad T. Keller, Hong Yin, Sophia Banton, Dean P. Jones, Hao Wu, Paul A. Dawson, Saul J. Karpen - Science Translational Medicine 2016 cited by 207

  3. Equol: History, Chemistry, and Formation

    Authors: Kenneth D.R. Setchell, Carlo Clerici - Journal of Nutrition 2010 cited by 510

  4. Complement drives glucosylceramide accumulation and tissue inflammation in Gaucher disease

    Authors: Manoj K. Pandey, Thomas Andrew Burrow, Reena Rani, Lisa J. Martin, David P. Witte, Kenneth D.R. Setchell, Mary McKay, Albert Frank Magnusen, Wujuan Zhang, Benjamin Liou, Jörg Köhl, Gregory A. Grabowski - Nature 2017 cited by 192

  5. Farnesoid X receptor antagonizes macrophage-dependent licensing of effector T lymphocytes and progression of sclerosing cholangitis

    Authors: Tiffany Shi, Astha Malik, Annika Yang vom Hofe, Louis Matuschek, Mary M. Mullen, Celine S. Lages, Ramesh Kudira, Ruchi Singh, Wujuan Zhang, Kenneth D.R. Setchell, David A. Hildeman, Chandrashekhar Pasare, Brandee Wagner, Alexander Miethke - Science Translational Medicine 2022 cited by 43

  6. The Clinical Importance of the Metabolite Equol—A Clue to the Effectiveness of Soy and Its Isoflavones

    Authors: Kenneth D.R. Setchell, Nadine M. Brown, Eva Lydeking-Olsen - Journal of Nutrition 2002 cited by 1,203

  7. Method of Defining Equol-Producer Status and Its Frequency among Vegetarians

    Authors: Kenneth D.R. Setchell, Sidney J Cole - Journal of Nutrition 2006 cited by 342

  8. Improving natural product research translation: From source to clinical trial

    Authors: Barbara C. Sorkin, Adam J. Kuszak, Gregory Bloss, Naomi K. Fukagawa, Freddie Ann Hoffman, Mahtab Jafari, Bruce Barrett, Paula N. Brown, Frederic D. Bushman, Steven Casper, Floyd H. Chilton, Christopher S. Coffey, Mário G. Ferruzzi, D. Craig Hopp, Máiréad Kiely, Daniël Lakens, John B. MacMillan, David Meltzer, Marco Pahor, Jeffrey Paul, Kathleen R. Pritchett‐Corning, Sara K. Quinney, Barbara Rehermann, Kenneth D.R. Setchell, Nisha S. Sipes, Jacqueline M. Stephens, D. Lansing Taylor, Hervé Tiriac, Michael A. Walters, Dan Xi, Giovanna Zappalà, Guido F. Pauli - The FASEB Journal 2019 cited by 96

  9. Maralixibat for the treatment of PFIC: Long‐term, IBAT inhibition in an open‐label, Phase 2 study

    Authors: Kathleen M. Loomes, Robert H. Squires, Déirdre Kelly, Sanjay Rajwal, Nisreen Soufi, Alain Lachaux, Irena Jankowska, Cara L. Mack, Kenneth D.R. Setchell, Palaniswamy Karthikeyan, Ciara Kennedy, Alejandro Dorenbaum, Nirav K. Desai, Will Garner, Thomas Jaecklin, Pamela Vig, Alexander Miethke, Richard J. Thompson - Hepatology Communications 2022 cited by 62

  10. Equol: Pharmacokinetics and Biological Actions ,

    Authors: Kenneth D.R. Setchell, Carlo Clerici - Journal of Nutrition 2010 cited by 210

  11. Evidence for lack of absorption of soy isoflavone glycosides in humans, supporting the crucial role of intestinal metabolism for bioavailability

    Authors: Kenneth D.R. Setchell, Nadine M. Brown, Linda Zimmer-Nechemias, Wayne T. Brashear, Brian Wolfe, Abby S. Kirschner, James E. Heubi - American Journal of Clinical Nutrition 2002 cited by 618

  12. Comparing the pharmacokinetics of daidzein and genistein with the use of 13C-labeled tracers in premenopausal women

    Authors: Kenneth D.R. Setchell, Marian S. Faughnan, Tony Avades, Linda Zimmer-Nechemias, Nadine M. Brown, Brian Wolfe, Wayne T. Brashear, Panjak Desai, Mark F. Oldfield, Nigel P. Botting, Aedín Cassidy - American Journal of Clinical Nutrition 2003 cited by 319

  13. Placebo‐Controlled Randomized Trial of an Intestinal Bile Salt Transport Inhibitor for Pruritus in Alagille Syndrome

    Authors: Benjamin L. Shneider, Cathie Spino, Binita M. Kamath, John Magee, Lee M. Bass, Kenneth D.R. Setchell, Alexander Miethke, Jean P. Molleston, Cara L. Mack, Robert H. Squires, Karen F. Murray, Kathleen M. Loomes, Philip Rosenthal, Saul J. Karpen, Daniel H. Leung, Stephen L. Guthery, Danny Thomas, Averell H. Sherker, Ronald J. Sokol - Hepatology Communications 2018 cited by 101

  14. Bioavailability of Pure Isoflavones in Healthy Humans and Analysis of Commercial Soy Isoflavone Supplements

    Authors: Kenneth D.R. Setchell, Nadine M. Brown, Pankaj B. Desai, Linda Zimmer-Nechemias, Brian Wolfe, Wayne T. Brashear, Abby S. Kirschner, Aedín Cassidy, James E. Heubi - Journal of Nutrition 2001 cited by 968

  15. Phytosterols Promote Liver Injury and Kupffer Cell Activation in Parenteral Nutrition–Associated Liver Disease

    Authors: Karim C. El Kasmi, Aimee L. Anderson, Michael W. Devereaux, Padade M. Vue, Wujuan Zhang, Kenneth D.R. Setchell, Saul J. Karpen, Ronald J. Sokol - Science Translational Medicine 2013 cited by 212

  16. Pharmacological inhibition of apical sodium‐dependent bile acid transporter changes bile composition and blocks progression of sclerosing cholangitis in multidrug resistance 2 knockout mice

    Authors: Alexander Miethke, Wujuan Zhang, Julia Simmons, Amy Taylor, Tiffany Shi, Shiva Kumar Shanmukhappa, Rebekah Karns, Shana White, Anil G. Jegga, Celine S. Lages, Stephenson W. Nkinin, Bradley T. Keller, Kenneth D.R. Setchell - Hepatology 2015 cited by 140

  17. Cognitive Effects of Soy Isoflavones in Patients with Alzheimer’s Disease

    Authors: Carey E. Gleason, Barbara L. Fischer, N. Maritza Dowling, Kenneth D.R. Setchell, Craig Atwood, Cynthia M. Carlsson, Sanjay Asthana - Journal of Alzheimer s Disease 2015 cited by 96

  18. Inhibition of Cdc42 activity extends lifespan and decreases circulating inflammatory cytokines in aged female C57BL/6 mice

    Authors: Maria Carolina Florian, Hanna Leins, Michael Gobs, Yang Han, Gina Marka, Karin Soller, Angelika Vollmer, Vadim Sakk, Kalpana Nattamai, Ahmad Rayes, Xueheng Zhao, Kenneth D.R. Setchell, Medhanie Mulaw, Wolfgang Wagner, Yi Zheng, Hartmut Geiger - Aging Cell 2020 cited by 67

  19. Dietary Isoflavones: Biological Effects and Relevance to Human Health

    Authors: Kenneth D.R. Setchell, Aedín Cassidy - Journal of Nutrition 1999 cited by 1,165

  20. S-Equol, a potent ligand for estrogen receptor β, is the exclusive enantiomeric form of the soy isoflavone metabolite produced by human intestinal bacterial flora1–4,

    Authors: Kenneth D.R. Setchell, Carlo Clerici, Edwin D. Lephart, Sidney J Cole, Claire Heenan, Danilo Castellani, Brian Wolfe, Linda Nechemias-Zimmer, Nadine M. Brown, Trent D Lund, Robert J. Handa, James E. Heubi - American Journal of Clinical Nutrition 2005 cited by 462

  21. Progranulin Recruits HSP70 to β-Glucocerebrosidase and Is Therapeutic Against Gaucher Disease

    Authors: Jinlong Jian, Qingyun Tian, Aubryanna Hettinghouse, Shuai Zhao, Helen Liu, Jianlu Wei, Gabriele Grünig, Wujuan Zhang, Kenneth D.R. Setchell, Ying Sun, Herman S. Overkleeft, Gerald L. Chan, Liu C - EBioMedicine 2016 cited by 108

  22. Metabolism of secoisolariciresinol-diglycoside the dietary precursor to the intestinally derived lignan enterolactone in humans

    Authors: Kenneth D.R. Setchell, Nadine M. Brown, Linda Zimmer-Nechemias, Brian Wolfe, Pinky Jha, James E. Heubi - Food & Function 2013 cited by 82

  23. Serum bile acids as a prognostic biomarker in biliary atresia following Kasai portoenterostomy

    Authors: Sanjiv Harpavat, Kieran Hawthorne, Kenneth D.R. Setchell, Monica Narvaez Rivas, Lisa Henn, Charlotte A. Beil, Saul J. Karpen, Vicky L. Ng, Estella M. Alonso, Jorge A. Bezerra, Stephen L. Guthery, Simon Horslen, Kathy M. Loomes, Patrick McKiernan, John C. Magee, Robert M. Merion, Jean P. Molleston, Philip J. Rosenthal, Richard J. Thompson, Kasper S. Wang, Ronald J. Sokol, Benjamin L. Shneider - Hepatology 2022 cited by 44

  24. Genistein, daidzein, and their .beta.-glycoside conjugates: antitumor isoflavones in soybean foods from American and Asian diets

    Authors: Lori Coward, Neil C. Barnes, Kenneth D.R. Setchell, Stephen Barnes - Journal of Agricultural and Food Chemistry 1993 cited by 884