David A. Lomas
Active 1992–2025
- Also published as
- David A Lomas
- 149
- Papers
- 34,617
- Citations
- 102
- h-index
- 144
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Medicine63.4%
- Biochemistry, Genetics and Molecular Biology27.1%
- Immunology and Microbiology2.6%
- Neuroscience1.5%
- Environmental Science0.8%
- Nursing0.7%
- Other3.9%
Topics
- Chronic Obstructive Pulmonary Disease (COPD) Research14%
- Asthma and respiratory diseases5.2%
- Respiratory Support and Mechanisms3.9%
- Alzheimer's disease research and treatments2.8%
- Protease and Inhibitor Mechanisms2.7%
- Neonatal Respiratory Health Research2%
- Other69.4%
Coauthors
- Edwin K. Silverman39
- Ruth Tal‐Singer36
- Àlvar Agustí28
- Bruce E. Miller27
- Stephen I. Rennard27
- Per Bakke26
- William MacNee26
- Harvey O. Coxson25
- Jørgen Vestbo24
- Lisa Edwards23
- Emiel F.�M. Wouters22
- Robin W. Carrell21
- Bartolomé R. Celli19
- Peter M.A. Calverley18
- Courtney Crim17
- Julie Yates17
- Elena Miranda16
- Damian C. Crowther14
- Amund Gulsvik13
- Dawn L. DeMeo13
- Craig P. Hersh12
- Michael H. Cho12
- Sreekumar Pillai12
- Gerard J. Criner11
All papers
- Susceptibility to Exacerbation in Chronic Obstructive Pulmonary Disease
Authors: John R. Hurst, Jørgen Vestbo, Antonio Anzueto, Nicholas Locantore, Hana Müllerová, Ruth Tal‐Singer, Bruce E. Miller, David A. Lomas, Àlvar Agustí, William MacNee, Peter M.A. Calverley, Stephen I. Rennard, Emiel F.�M. Wouters, Jadwiga A. Wedzicha - New England Journal of Medicine 2010 cited by 2,979
- Once-Daily Single-Inhaler Triple versus Dual Therapy in Patients with COPD
Authors: David A. Lipson, Frank Barnhart, Noushin Brealey, Jean Brooks, Gerard J. Criner, Nicola C. Day, Mark T. Dransfield, David Halpin, MeiLan K. Han, Christine Jones, Sally Kilbride, Peter Lange, David A. Lomas, Fernando J. Martínez, Dave Singh, Maggie Tabberer, Robert A. Wise, Steven Pascoe - New England Journal of Medicine 2018 cited by 1,262
- Alpha 1 -Antitrypsin Deficiency
Authors: Pavel Strnad, Noel G. McElvaney, David A. Lomas - New England Journal of Medicine 2020 cited by 511
- α1-Antitrypsin deficiency
Authors: Catherine M. Greene, Stefan J. Marciniak, Jeffrey Teckman, Ilaria Ferrarotti, Mark Brantly, David A. Lomas, James K. Stoller, Noel G. McElvaney - Nature Reviews Disease Primers 2016 cited by 319
- Persistent Systemic Inflammation is Associated with Poor Clinical Outcomes in COPD: A Novel Phenotype
Authors: Àlvar Agustí, Lisa Edwards, Stephen I. Rennard, William MacNee, Ruth Tal‐Singer, Bruce E. Miller, Jørgen Vestbo, David A. Lomas, Peter M.A. Calverley, Emiel F.�M. Wouters, Courtney Crim, Julie Yates, Edwin K. Silverman, Harvey O. Coxson, Per Bakke, Ruth J. Mayer, Bartolomé R. Celli, for the Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints (ECLIPSE) Investigators - PLoS ONE 2012 cited by 850
- Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations
Authors: Phuwanat Sakornsakolpat, Dmitry Prokopenko, Maxime Lamontagne, Nicola Reeve, Anna L. Guyatt, Victoria E. Jackson, Nick Shrine, Dandi Qiao, Traci M. Bartz, Deog Kyeom Kim, Mi Kyeong Lee, Jeanne C. Latourelle, Xingnan Li, Jarrett D. Morrow, Ma’en Obeidat, Annah B. Wyss, Per Bakke, R. Graham Barr, Terri H. Beaty, Steven A. Belinsky, Guy Brusselle, James D. Crapo, Kim de Jong, Dawn L. DeMeo, Tasha E. Fingerlin, Sina A. Gharib, Amund Gulsvik, Ian P. Hall, John E. Hokanson, Woo Jin Kim, David A. Lomas, Stephanie J. London, Deborah A. Meyers, George O'connor, Stephen I. Rennard, David A. Schwartz, Paweł Śliwiński, David Sparrow, David P. Strachan, Ruth Tal‐Singer, Yohannes Tesfaigzi, Jørgen Vestbo, Judith M. Vonk, Jae‐Joon Yim, Xiaobo Zhou, Yohan Bossé, Ani Manichaikul, Lies Lahousse, Edwin K. Silverman, H. Marike Boezen, Louise V. Wain, Martin D. Tobin, Brian D. Hobbs, Michael H. Cho, Nick Shrine, Anna L. Guyatt, Chiara Batini, Jing Hua Zhao, Matthias Wielscher, Understanding Society Scientific Group, Stefan Weiß, Katherine A. Kentistou, James P. Cook, Jennie Hui, Stefan Karrasch, Medea Imboden, Sarah E. Harris, Jonathan Marten, Stefan Enroth, Shona M. Kerr, Ida Surakka, Véronique Vitart, Terho Lehtimäki, Ralf Ewert, Christian Gieger, Georg Homuth, Peter K. Joshi, Claudia Langenberg, Lars Lind, Jian’an Luan, Anubha Mahajan, Alison D. Murray, David J. Porteous, Rajesh Rawal, Blair H. Smith, Paul R. H. J. Timmers, Olli Raitakari, Mika Kähönen, Ozren Polašek, Ulf Gyllensten, Igor Rudan, Ian J. Deary, Nicole Probst‐Hensch, Holger Schulz, Alan L. James, James F. Wilson, Beate Stubbe, Eleftheria Zeggini, Marjo‐Riitta Järvelin, Nick Wareham and 89 more - Nature Genetics 2019 cited by 423
- Characterisation of COPD heterogeneity in the ECLIPSE cohort
Authors: the Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints (ECLIPSE) investigators, Àlvar Agustí, Peter M.A. Calverley, Bartolomé R. Celli, Harvey O. Coxson, Lisa Edwards, David A. Lomas, William MacNee, Bruce E. Miller, Steve Rennard, Edwin K. Silverman, Ruth Tal‐Singer, E.F.M. Wouters, Julie Yates, Jørgen Vestbo - Respiratory Research 2010 cited by 1,160
- Changes in Forced Expiratory Volume in 1 Second over Time in COPD
Authors: Jørgen Vestbo, Lisa Edwards, Paul D. Scanlon, Julie Yates, Àlvar Agustí, Per Bakke, Peter M.A. Calverley, Bartolomé R. Celli, Harvey O. Coxson, Courtney Crim, David A. Lomas, William MacNee, Bruce E. Miller, Edwin K. Silverman, Ruth Tal‐Singer, E.F.M. Wouters, Stephen I. Rennard - New England Journal of Medicine 2011 cited by 958
- Comorbidity, systemic inflammation and outcomes in the ECLIPSE cohort
Authors: Joy Miller, Lisa Edwards, Àlvar Agustí, Per Bakke, Peter M.A. Calverley, Bartolomé R. Celli, Harvey O. Coxson, Courtney Crim, David A. Lomas, Bruce E. Miller, Steve Rennard, Edwin K. Silverman, Ruth Tal‐Singer, Jørgen Vestbo, Emiel F.�M. Wouters, Julie Yates, William MacNee - Respiratory Medicine 2013 cited by 437
- Reduction in All-Cause Mortality with Fluticasone Furoate/Umeclidinium/Vilanterol in Patients with Chronic Obstructive Pulmonary Disease
Authors: David A. Lipson, Courtney Crim, Gerard J. Criner, Nicola C. Day, Mark T. Dransfield, David Halpin, MeiLan K. Han, Christine Jones, Sally Kilbride, Peter Lange, David A. Lomas, Sally Lettis, P Manchester, Neil Martin, Dawn Midwinter, Andrea Morris, Steven Pascoe, Dave Singh, Robert A. Wise, Fernando J. Martínez - American Journal of Respiratory and Critical Care Medicine 2020 cited by 251
- Blood eosinophils and treatment response with triple and dual combination therapy in chronic obstructive pulmonary disease: analysis of the IMPACT trial
Authors: Steven Pascoe, Neil Barnes, Guy Brusselle, Chris Compton, Gerard J. Criner, Mark T. Dransfield, David Halpin, MeiLan K. Han, Benjamin Hartley, Peter Lange, Sally Lettis, David A. Lipson, David A. Lomas, Fernando J. Martínez, Alberto Papi, Nicolás Roche, Ralf J.P. van der Valk, Robert A. Wise, Dave Singh - The Lancet Respiratory Medicine 2019 cited by 240
- Endoplasmic reticulum dysfunction in neurological disease
Authors: Benoit D. Roussel, Antonina J. Kruppa, Elena Miranda, Damian C. Crowther, David A. Lomas, Stefan J. Marciniak - The Lancet Neurology 2012 cited by 444
- Inflammatory Biomarkers Improve Clinical Prediction of Mortality in Chronic Obstructive Pulmonary Disease
Authors: Bartolomé R. Celli, Nicholas Locantore, Julie Yates, Ruth Tal‐Singer, Bruce E. Miller, Per Bakke, Peter M.A. Calverley, Harvey O. Coxson, Courtney Crim, Lisa Edwards, David A. Lomas, Annelyse Duvoix, William MacNee, Stephen I. Rennard, Edwin K. Silverman, Jørgen Vestbo, Emiel F.�M. Wouters, Àlvar Agustí - American Journal of Respiratory and Critical Care Medicine 2012 cited by 430
- Evaluation of COPD Longitudinally to Identify Predictive Surrogate End-points (ECLIPSE)
Authors: Jørgen Vestbo, W. J. Anderson, Harvey O. Coxson, Courtney Crim, F. Dawber, Lisa Edwards, Gerry Hagan, Katharine Knobil, David A. Lomas, William MacNee, Edwin K. Silverman, Ruth Tal‐Singer, on behalf of the ECLIPSE investigators - European Respiratory Journal 2008 cited by 769
- The mechanism of Z α1-antitrypsin accumulation in the liver
Authors: David A. Lomas, Dyfed LI-Evans, J.T. Finch, Robin W. Carrell - Nature 1992 cited by 1,058
- Risk loci for chronic obstructive pulmonary disease: a genome-wide association study and meta-analysis
Authors: Michael H. Cho, Merry‐Lynn McDonald, Xiaobo Zhou, Manuel Mattheisen, Peter J. Castaldi, Craig P. Hersh, Dawn L. DeMeo, Jody Sylvia, John Ziniti, Nan M. Laird, Christoph Lange, Augusto A. Litonjua, David Sparrow, Richard Casaburi, R. Graham Barr, Elizabeth A. Regan, Barry J. Make, John E. Hokanson, Sharon M. Lutz, Tanda M. Dudenkov, Homayoon Farzadegan, Jacqueline B. Hetmanski, Ruth Tal‐Singer, David A. Lomas, Per Bakke, Amund Gulsvik, James D. Crapo, Edwin K. Silverman, Terri H. Beaty - The Lancet Respiratory Medicine 2014 cited by 362
- Iron Promotes the Toxicity of Amyloid β Peptide by Impeding Its Ordered Aggregation
Authors: Beinan Liu, Aileen M. Moloney, Sarah Meehan, Kyle L. Morris, Sally E. Thomas, Louise C. Serpell, Robert C. Hider, Stefan J. Marciniak, David A. Lomas, Damian C. Crowther - Journal of Biological Chemistry 2010 cited by 220
- FULFIL Trial: Once-Daily Triple Therapy for Patients with Chronic Obstructive Pulmonary Disease
Authors: David A. Lipson, Helen Barnacle, Ruby Birk, Noushin Brealey, Nicholas Locantore, David A. Lomas, Andrea Ludwig-Sengpiel, Rajat Mohindra, Maggie Tabberer, Chang‐Qing Zhu, Steven Pascoe - American Journal of Respiratory and Critical Care Medicine 2017 cited by 330
- Quantitative Computed Tomography Measures of Pectoralis Muscle Area and Disease Severity in Chronic Obstructive Pulmonary Disease. A Cross-Sectional Study
Authors: Merry‐Lynn McDonald, Alejandro A. Díaz, James C. Ross, Raúl San Jośe Estépar, Linfu Zhou, Elizabeth A. Regan, Eric Eckbo, Nina Muralidhar, Carolyn E. Come, Michael H. Cho, Craig P. Hersh, Christoph Lange, Emiel F.�M. Wouters, Richard Casaburi, Harvey O. Coxson, William MacNee, Stephen I. Rennard, David A. Lomas, Àlvar Agustí, Bartolomé R. Celli, Jennifer L. Black‐Shinn, Gregory L. Kinney, Sharon M. Lutz, John E. Hokanson, Edwin K. Silverman, George R. Washko - Annals of the American Thoracic Society 2014 cited by 248
- The Serpins Are an Expanding Superfamily of Structurally Similar but Functionally Diverse Proteins
Authors: Gary A. Silverman, Phillip I. Bird, Robin W. Carrell, Frank Church, Paul Coughlin, Peter G.W. Gettins, James A. Irving, David A. Lomas, Cliff J. Luke, Richard W. Moyer, Philip A. Pemberton, Eileen Remold‐O’Donnell, Guy S. Salvesen, James Travis, James C. Whisstock - Journal of Biological Chemistry 2001 cited by 1,212
- Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis
Authors: COPDGene Investigators, Brian D. Hobbs, ECLIPSE Investigators, LifeLines Investigators, International COPD Genetics Network Investigators, UK BiLEVE Investigators, Kim de Jong, Maxime Lamontagne, Yohan Bossé, Nick Shrine, María Soler Artigas, Louise V. Wain, Ian P. Hall, Victoria E. Jackson, Annah B. Wyss, Stephanie J. London, Kari E. North, Nora Franceschini, David P. Strachan, Terri H. Beaty, John E. Hokanson, James D. Crapo, Peter J. Castaldi, Robert Chase, Traci M. Bartz, Susan R. Heckbert, Bruce M. Psaty, Sina A. Gharib, Pieter Zanen, Jan Willem J. Lammers, Matthijs Oudkerk, Harry J.M. Groen, Nicholas Locantore, Ruth Tal‐Singer, Stephen I. Rennard, Jørgen Vestbo, Wim Timens, Peter D. Paré, Jeanne C. Latourelle, Josée Dupuis, George O'connor, Jemma B. Wilk, Woo Jin Kim, Mi Kyeong Lee, Yeon‐Mok Oh, Judith M. Vonk, Harry J. de Koning, Shuguang Leng, Steven A. Belinsky, Yohannes Tesfaigzi, Ani Manichaikul, Xin‐Qun Wang, Stephen S. Rich, R. Graham Barr, David Sparrow, Augusto A. Litonjua, Per Bakke, Amund Gulsvik, Lies Lahousse, Guy Brusselle, Bruno H. Stricker, André G. Uitterlinden, Elizabeth J. Ampleford, Eugene R. Bleecker, Prescott G. Woodruff, Deborah A. Meyers, Dandi Qiao, David A. Lomas, Jae‐Joon Yim, Deog Kyeom Kim, I Hawryłkiewicz, Paweł Śliwiński, Megan Hardin, Tasha E. Fingerlin, David A. Schwartz, Dirkje S. Postma, William MacNee, Martin D. Tobin, Edwin K. Silverman, H. Marike Boezen, Michael H. Cho - Nature Genetics 2017 cited by 442
- Six-Minute-Walk Test in Chronic Obstructive Pulmonary Disease
Authors: Michael I. Polkey, Martijn A. Spruit, Lisa Edwards, Michael L. Watkins, Víctor Pinto-Plata, Jørgen Vestbo, Peter M.A. Calverley, Ruth Tal‐Singer, Àlvar Agustí, Per Bakke, Harvey O. Coxson, David A. Lomas, William MacNee, Stephen I. Rennard, Edwin K. Silverman, Bruce E. Miller, Courtney Crim, Julie Yates, Emiel F.�M. Wouters, Bartolomé R. Celli - American Journal of Respiratory and Critical Care Medicine 2012 cited by 328
- Coronary artery calcification is increased in patients with COPD and associated with increased morbidity and mortality
Authors: Michelle C. Williams, John T. Murchison, Lisa Edwards, Àlvar Agustí, Per Bakke, Peter M.A. Calverley, Bartolomé R. Celli, Harvey O. Coxson, Courtney Crim, David A. Lomas, Bruce E. Miller, Steve Rennard, Edwin K. Silverman, Ruth Tal‐Singer, Jørgen Vestbo, Emiel F.�M. Wouters, Julie Yates, Edwin J.R. van Beek, David E. Newby, William MacNee, for the Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints (ECLIPSE) investigators - Thorax 2014 cited by 202
- Hepatobiliary phenotypes of adults with alpha-1 antitrypsin deficiency
Authors: Malin Fromme, Carolin V. Schneider, Vítor Magno Pereira, Karim Hamesch, Mònica Pons, Matthias Reichert, Federica Benini, Paul Ellis, Katrine Holtz Thorhauge, Mattias Mandorfer, Barbara Burbaum, V Woditsch, Joanna Chorostowska‐Wynimko, Jef Verbeek, Frederik Nevens, Joan Genescà, Marc Miravitlles, Alexa Núñez, Benedikt Schaefer, Heinz Zoller, Sabina Janciauskiene, Nélia Abreu, Luís Jasmins, Rui Gaspar, Rodrigo Liberal, Guilherme Macedo, Ravi Mahadeva, Catarina Gomes, Kai Markus Schneider, Michael Trauner, Aleksander Krag, Bibek Gooptu, Douglas Thorburn, Aileen Marshall, John R. Hurst, David A. Lomas, Frank Lammert, Nadine T. Gaisa, Virginia Clark, William Griffiths, Christian Trautwein, Alice Turner, Noel G. McElvaney, Pavel Strnad - Gut 2021 cited by 76
