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Guy S. Salvesen

Active 1980–2024

182
Papers
75,016
Citations
123
h-index
182
i10-index

Citations

Citations per year for Guy S. Salvesen1979: 6 citations1980: 1 citations1981: 11 citations1982: 4 citations1983: 8 citations1984: 23 citations1985: 23 citations1986: 38 citations1987: 51 citations1988: 57 citations1989: 59 citations1990: 56 citations1991: 77 citations1992: 76 citations1993: 127 citations1994: 192 citations1995: 312 citations1996: 406 citations1997: 626 citations1998: 955 citations1999: 1,219 citations2000: 1,370 citations2001: 1,210 citations2002: 1,096 citations2003: 1,108 citations2004: 1,149 citations2005: 861 citations2006: 768 citations2007: 702 citations2008: 727 citations2009: 665 citations2010: 685 citations2011: 643 citations2012: 692 citations2013: 570 citations2014: 612 citations2015: 456 citations2016: 508 citations2017: 510 citations2018: 458 citations2019: 1,326 citations2020: 1,593 citations2021: 1,418 citations2022: 1,253 citations2023: 924 citations2024: 1,178 citations2025: 511 citations2026: 14 citations

Citation sources

Countries

World map of the countries and regions citing this authorUnited States: 8,704 citing papers, 33.8% of this breakdownChina: 2,752 citing papers, 10.7% of this breakdownGermany: 1,507 citing papers, 5.8% of this breakdownUnited Kingdom: 1,468 citing papers, 5.7% of this breakdownCanada: 1,104 citing papers, 4.3% of this breakdownJapan: 1,076 citing papers, 4.2% of this breakdownFrance: 908 citing papers, 3.5% of this breakdownAustralia: 797 citing papers, 3.1% of this breakdownItaly: 588 citing papers, 2.3% of this breakdownSpain: 473 citing papers, 1.8% of this breakdownSouth Korea: 470 citing papers, 1.8% of this breakdownSweden: 452 citing papers, 1.8% of this breakdown
0%33.8%Other 21.2%

Institutions

Fields

  • Biochemistry, Genetics and Molecular Biology54.6%
  • Medicine28.6%
  • Immunology and Microbiology6.3%
  • Neuroscience4.4%
  • Agricultural and Biological Sciences1.2%
  • Chemistry1.1%
  • Other3.8%

Topics

  • Cell death mechanisms and regulation8.8%
  • Inflammasome and immune disorders4.5%
  • Alzheimer's disease research and treatments3.1%
  • Autophagy in Disease and Therapy2.1%
  • Protease and Inhibitor Mechanisms2.1%
  • Mitochondrial Function and Pathology1.9%
  • Other77.5%

Coauthors

All papers

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  1. Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling

    Authors: Nobuhiko Kayagaki, Irma B. Stowe, Bettina L. Lee, Karen O’Rourke, Keith R. Anderson, Søren Warming, Trinna Cuellar, Benjamin Haley, Merone Roose‐Girma, Qui Phung, Peter S. Liu, Jennie R. Lill, Hong Li, Jiansheng Wu, Sarah Kummerfeld, Juan Zhang, Wyne P. Lee, Scott J. Snipas, Guy S. Salvesen, Lucy X. Morris, Linda Fitzgerald, Yafei Zhang, Edward M. Bertram, Christopher C. Goodnow, Vishva M. Dixit - Nature 2015 cited by 3,743

  2. Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease.

    Authors: Warren J. Strittmatter, Ann M. Saunders, D. E. Schmechel, M. A. Pericak‐Vance, Jan J. Enghild, Guy S. Salvesen, A D Roses - National Academy of Sciences, Proceedings of the National Academy of Sciences 1993 cited by 4,286

  3. Catalytic activity of the caspase-8–FLIPL complex inhibits RIPK3-dependent necrosis

    Authors: Andrew Oberst, Christopher P. Dillon, Ricardo Weinlich, Laura L. McCormick, Patrick Fitzgerald, Cristina Pop, Razqallah Hakem, Guy S. Salvesen, Douglas R. Green - Nature 2011 cited by 1,276

  4. Pannexin 1 channels mediate ‘find-me’ signal release and membrane permeability during apoptosis

    Authors: Faraaz B. Chekeni, Michael R. Elliott, Joanna K. Sandilos, Scott F. Walk, Jason M. Kinchen, Eduardo R. Lazarowski, Allison J. Armstrong, Silvia Peñuela, Dale W. Laird, Guy S. Salvesen, Brant E. Isakson, Douglas A. Bayliss, Kodi S. Ravichandran - Nature 2010 cited by 1,115

  5. Cathepsin G Inhibition by Serpinb1 and Serpinb6 Prevents Programmed Necrosis in Neutrophils and Monocytes and Reduces GSDMD-Driven Inflammation

    Authors: Sabrina Sofia Burgener, Nathan Georges François Leborgne, Scott J. Snipas, Guy S. Salvesen, Phillip I. Bird, Charaf Benarafa - Cell Reports 2019 cited by 275

  6. The apoptosome: signalling platform of cell death

    Authors: Stefan J. Riedl, Guy S. Salvesen - Nature Reviews Molecular Cell Biology 2007 cited by 1,065

  7. Regulation of Histone Acetylation by Autophagy in Parkinson Disease

    Authors: Goonho Park, Jieqiong Tan, Guillermina Garcia, Yunyi Kang, Guy S. Salvesen, Zhuohua Zhang - Journal of Biological Chemistry 2016 cited by 163

  8. Mechanisms of caspase activation

    Authors: Kelly M. Boatright, Guy S. Salvesen - Current Opinion in Cell Biology 2003 cited by 1,371

  9. Emerging principles in protease-based drug discovery

    Authors: Marcin Drąg, Guy S. Salvesen - Nature Reviews Drug Discovery 2010 cited by 593

  10. A primer on caspase mechanisms

    Authors: Monica L. Gonzalez Ramirez, Guy S. Salvesen - Seminars in Cell and Developmental Biology 2018 cited by 165

  11. Yama/CPP32β, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase

    Authors: Muneesh Tewari, Long T. Quan, Karen O’Rourke, Serge Desnoyers, Zhi Jiang Zeng, David R Beidler, Guy G. Poirier, Guy S. Salvesen, Vishva M. Dixit - Cell 1995 cited by 2,393

  12. Regulation of Cell Death Protease Caspase-9 by Phosphorylation

    Authors: Michael H. Cardone, Natalie Roy, Henning R. Stennicke, Guy S. Salvesen, Thomas Franke, Eric J. Stanbridge, Steven M. Frisch, John C. Reed - Science 1998 cited by 3,127

  13. Human ICE/CED-3 Protease Nomenclature

    Authors: Emad S. Alnemri, David J. Livingston, Donald W. Nicholson, Guy S. Salvesen, Nancy A. Thornberry, Winnie W. Wong, Junying Yuan - Cell 1996 cited by 2,383

  14. Binding of human apolipoprotein E to synthetic amyloid beta peptide: isoform-specific effects and implications for late-onset Alzheimer disease.

    Authors: Warren J. Strittmatter, Karl H. Weisgraber, Daoyuan Huang, Li Dong, Guy S. Salvesen, Margaret A. Pericak‐Vance, D. E. Schmechel, Ann M. Saunders, Dmitry Goldgaber, Allen D. Roses - National Academy of Sciences, Proceedings of the National Academy of Sciences 1993 cited by 1,362

  15. The Fas–FADD death domain complex structure unravels signalling by receptor clustering

    Authors: Fiona L. Scott, Boguslaw Stec, Cristina Pop, Małgorzata K. Dobaczewska, JeongEun J. Lee, Edward Monosov, Howard Robinson, Guy S. Salvesen, Robert Schwarzenbacher, Stefan J. Riedl - Nature 2008 cited by 376

  16. Regulated Cell Death: Signaling and Mechanisms

    Authors: Avi Ashkenazi, Guy S. Salvesen - Annual Review of Cell and Developmental Biology 2014 cited by 278

  17. Human Caspases: Activation, Specificity, and Regulation

    Authors: Cristina Pop, Guy S. Salvesen - Journal of Biological Chemistry 2009 cited by 731

  18. FLIPL induces caspase 8 activity in the absence of interdomain caspase 8 cleavage and alters substrate specificity

    Authors: Cristina Pop, Andrew Oberst, Marcin Drąg, Bram J. van Raam, Stefan J. Riedl, Douglas R. Green, Guy S. Salvesen - Biochemical Journal 2011 cited by 225

  19. The caspase-8 inhibitor emricasan combines with the SMAC mimetic birinapant to induce necroptosis and treat acute myeloid leukemia

    Authors: Gabriela Brumatti, Chunyan Ma, Najoua Lalaoui, Nhu-Y Nguyen, Mario Navarro, Maria C. Tanzer, Jennifer Richmond, Margherita Ghisi, Jessica M. Salmon, Natasha Silke, Giovanna Pomilio, Stefan Glaser, Elisha de Valle, Raffi Gugasyan, Mark A. Gurthridge, Stephen M. Condon, Ricky W. Johnstone, Richard B. Lock, Guy S. Salvesen, Andrew H. Wei, David L. Vaux, Paul G. Ekert, John Silke - Science Translational Medicine 2016 cited by 186

  20. Regulation of the Apaf-1–caspase-9 apoptosome

    Authors: Shawn B. Bratton, Guy S. Salvesen - Journal of Cell Science 2010 cited by 420

  21. The Pyroptotic Cell Death Effector Gasdermin D Is Activated by Gout-Associated Uric Acid Crystals but Is Dispensable for Cell Death and IL-1β Release

    Authors: Maryam Rashidi, Daniel S. Simpson, Anne Hempel, Daniel Frank, Emma J. Petrie, Angelina J. Vince, Rebecca Feltham, Jane Murphy, Simon Chatfield, Guy S. Salvesen, James M. Murphy, Ian P. Wicks, James E. Vince - The Journal of Immunology 2019 cited by 120

  22. Pro-caspase-3 Is a Major Physiologic Target of Caspase-8

    Authors: Henning R. Stennicke, Juliane M. Jürgensmeier, Hwain Shin, Quinn L. Deveraux, Beni B. Wolf, Xiaohe Yang, Qiao Zhou, H. Michael Ellerby, Lisa Ellerby, Dale E. Bredesen, Douglas R. Green, John C. Reed, Christopher J. Froelich, Guy S. Salvesen - Journal of Biological Chemistry 1998 cited by 751

  23. X-linked IAP is a direct inhibitor of cell-death proteases

    Authors: Quinn L. Deveraux, Ryōsuke Takahashi, Guy S. Salvesen, John C. Reed - Nature 1997 cited by 1,955

  24. The Serpins Are an Expanding Superfamily of Structurally Similar but Functionally Diverse Proteins

    Authors: Gary A. Silverman, Phillip I. Bird, Robin W. Carrell, Frank Church, Paul Coughlin, Peter G.W. Gettins, James A. Irving, David A. Lomas, Cliff J. Luke, Richard W. Moyer, Philip A. Pemberton, Eileen Remold‐O’Donnell, Guy S. Salvesen, James Travis, James C. Whisstock - Journal of Biological Chemistry 2001 cited by 1,212