Ricky W. Johnstone
Active 1948–2025
- 144
- Papers
- 34,494
- Citations
- 97
- h-index
- 144
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Biochemistry, Genetics and Molecular Biology54.3%
- Medicine30.6%
- Immunology and Microbiology10.1%
- Neuroscience0.9%
- Engineering0.8%
- Chemistry0.7%
- Other2.6%
Topics
- Histone Deacetylase Inhibitors Research7.6%
- Protein Degradation and Inhibitors5.1%
- Epigenetics and DNA Methylation4.1%
- Cell death mechanisms and regulation2.8%
- Immune Cell Function and Interaction2.6%
- Ubiquitin and proteasome pathways2.2%
- Other75.6%
Coauthors
- Mark J. Smyth22
- Stephin J. Vervoort19
- Jake Shortt18
- Joseph A. Trapani17
- Leonie A. Cluse15
- Grant A. McArthur12
- Simon J. Hogg12
- Conor J. Kearney11
- Gareth P. Gregory11
- Lev M. Kats11
- H. Miles Prince10
- Jane Oliaro10
- Jennifer R. Devlin10
- Andrea Newbold9
- Carleen Cullinane9
- Paul A. Beavis9
- Phillip K. Darcy9
- Astrid A. Ruefli8
- Izabela Todorovski8
- Madison J. Kelly8
- Richard B. Pearson8
- Ben P. Martin7
- Kelly M. Ramsbottom7
- Kym L. Stanley7
All papers
- Targeting the epigenetic regulation of antitumour immunity
Authors: Simon J. Hogg, Paul A. Beavis, Mark A. Dawson, Ricky W. Johnstone - Nature Reviews Drug Discovery 2020 cited by 620
- Histone deacetylases and their inhibitors in cancer, neurological diseases and immune disorders
Authors: Katrina J. Falkenberg, Ricky W. Johnstone - Nature Reviews Drug Discovery 2014 cited by 1,525
- Tumor immune evasion arises through loss of TNF sensitivity
Authors: Conor J. Kearney, Stephin J. Vervoort, Simon J. Hogg, Kelly M. Ramsbottom, Andrew J. Freeman, Najoua Lalaoui, Lizzy Pijpers, Jessica Michie, Kristin Brown, Deborah A. Knight, Vivien R. Sutton, Paul A. Beavis, Ilia Voskoboinik, Phillip K. Darcy, John Silke, Joseph A. Trapani, Ricky W. Johnstone, Jane Oliaro - Science Immunology 2018 cited by 393
- New and emerging HDAC inhibitors for cancer treatment
Authors: Alison C. West, Ricky W. Johnstone - Journal of Clinical Investigation 2014 cited by 1,377
- Inhibitors of histone acetyltransferases KAT6A/B induce senescence and arrest tumour growth
Authors: Jonathan B. Baell, David J. Leaver, S.J. Hermans, Gemma L. Kelly, Margs S. Brennan, Natalie L. Downer, Nghi Nguyen, Johannes Wichmann, Helen M. McRae, Yuqing Yang, Ben Cleary, H. Rachel Lagiakos, Stephen Mieruszynski, Guido Pacini, Hannah Vanyai, Maria Bergamasco, Rose E. May, Bethany K. Davey, Kimberly J Morgan, A.J. Sealey, Beinan Wang, Natasha Zamudio, Stephen Wilcox, Alexandra L. Garnham, Bilal N. Sheikh, Brandon J. Aubrey, Karen Doggett, Matthew Chung, Melanie de Silva, John D. Bentley, Pat Pilling, Meghan Hattarki, Olan Dolezal, Matthew L. Dennis, Hendrik Falk, Bin Ren, Susan A. Charman, Karen L. White, Jai Rautela, Andrea Newbold, Edwin D. Hawkins, Ricky W. Johnstone, Nicholas D. Huntington, Thomas S. Peat, Joan K. Heath, Andreas Strasser, Michael W. Parker, Gordon K. Smyth, Ian P. Street, Brendon J. Monahan, Anne K. Voss, Tim Thomas - Nature 2018 cited by 314
- Discovery of Mcl-1-specific inhibitor AZD5991 and preclinical activity in multiple myeloma and acute myeloid leukemia
Authors: Adriana E. Tron, Matthew A. Belmonte, Ammar Adam, Brian Aquila, Lawrence Boise, Elisabetta Chiarparin, Justin Cidado, Kevin J. Embrey, Eric T. Gangl, Francis D. Gibbons, Gareth P. Gregory, David Hargreaves, J. Adam Hendricks, Jeffrey W. Johannes, Ricky W. Johnstone, Steven L. Kazmirski, Jason G. Kettle, Michelle L. Lamb, Shannon M. Matulis, Ajay K. Nooka, Martin J. Packer, Bo Peng, Philip B. Rawlins, Daniel Robbins, Alwin G. Schuller, Nancy Su, Wenzhan Yang, Qing Ye, Xiaolan Zheng, J. Paul Secrist, Edwin Clark, David M. Wilson, Stephen E. Fawell, Alexander W. Hird - Nature Communications 2018 cited by 486
- Anticancer activities of histone deacetylase inhibitors
Authors: Jessica E. Bolden, Melissa J. Peart, Ricky W. Johnstone - Nature Reviews Drug Discovery 2006 cited by 2,917
- Structures of the HIN Domain:DNA Complexes Reveal Ligand Binding and Activation Mechanisms of the AIM2 Inflammasome and IFI16 Receptor
Authors: Tengchuan Jin, Andrew Perry, Jiansheng Jiang, Patrick Smith, James A. Curry, Leonie Unterholzner, Zhaozhao Jiang, Gábor Horváth, Vijay Rathinam, Ricky W. Johnstone, Veit Hornung, Eicke Latz, Andrew Bowie, Katherine A. Fitzgerald, Tsan Sam Xiao - Immunity 2012 cited by 560
- The PP2A-Integrator-CDK9 axis fine-tunes transcription and can be targeted therapeutically in cancer
Authors: Stephin J. Vervoort, Sarah A. Welsh, Jennifer R. Devlin, Elisa Barbieri, Deborah A. Knight, Sarah Offley, Stefan Bjelosevic, Matteo Costacurta, Izabela Todorovski, Conor J. Kearney, Jarrod J. Sandow, Zheng Fan, Benjamin J. Blyth, Victoria M. McLeod, Joseph H.A. Vissers, Karolina Pavic, Ben P. Martin, Gareth P. Gregory, Elena Demosthenous, Magnus Zethoven, Isabella Y. Kong, Edwin D. Hawkins, Simon J. Hogg, Madison J. Kelly, Andrea Newbold, Kaylene J. Simpson, Otto Kauko, Kieran F. Harvey, Michael Ohlmeyer, Jukka Westermarck, Nathanael S. Gray, Alessandro Gardini, Ricky W. Johnstone - Cell 2021 cited by 227
- BET-Bromodomain Inhibitors Engage the Host Immune System and Regulate Expression of the Immune Checkpoint Ligand PD-L1
Authors: Simon J. Hogg, Stephin J. Vervoort, Sumit Deswal, Christopher J. Ott, Jason Li, Leonie A. Cluse, Paul A. Beavis, Phillip K. Darcy, Benjamin Martin, Andrew Spencer, Anna K. Traunbauer, Irina Sadovnik, Karin Bauer, Peter Valent, James E. Bradner, Johannes Zuber, Jake Shortt, Ricky W. Johnstone - Cell Reports 2017 cited by 300
- Targeting histone acetylation dynamics and oncogenic transcription by catalytic P300/CBP inhibition
Authors: Simon J. Hogg, Olga Motorna, Leonie A. Cluse, Timothy M. Johanson, Hannah D. Coughlan, Ramya Raviram, Robert M. Myers, Matteo Costacurta, Izabela Todorovski, Lizzy Pijpers, Stefan Bjelosevic, Tobias Williams, Shannon N. Huskins, Conor J. Kearney, Jennifer R. Devlin, Zheng Fan, Jafar S. Jabbari, Ben P. Martin, Mohamed Fareh, Madison J. Kelly, Daphné Dupéré-Richer, Jarrod J. Sandow, Breon Feran, Deborah A. Knight, Tiffany Khong, Andrew Spencer, Simon J. Harrison, Gareth P. Gregory, Vihandha O. Wickramasinghe, Andrew I. Webb, Phillippa C. Taberlay, Kenneth D. Bromberg, Albert Lai, Anthony T. Papenfuss, Gordon K. Smyth, Rhys S. Allan, Jonathan D. Licht, Dan A. Landau, Omar Abdel‐Wahab, Jake Shortt, Stephin J. Vervoort, Ricky W. Johnstone - Molecular Cell 2021 cited by 170
- Targeting transcription cycles in cancer
Authors: Stephin J. Vervoort, Jennifer R. Devlin, Nicholas Kwiatkowski, Mingxing Teng, Nathanael S. Gray, Ricky W. Johnstone - Nature reviews. Cancer 2021 cited by 168
- IL-15 Preconditioning Augments CAR T Cell Responses to Checkpoint Blockade for Improved Treatment of Solid Tumors
Authors: Lauren Giuffrida, Kevin Sek, Melissa A. Henderson, Imran G. House, Junyun Lai, Amanda X. Y. Chen, Kirsten L. Todd, Emma V. Petley, Sherly Mardiana, Izabela Todorovski, Emily Gruber, Madison J. Kelly, Benjamin Solomon, Stephin J. Vervoort, Ricky W. Johnstone, Ian A. Parish, Paul J. Neeson, Lev M. Kats, Phillip K. Darcy, Paul A. Beavis - Molecular Therapy 2020 cited by 107
- BET inhibitor resistance emerges from leukaemia stem cells
Authors: Chun Yew Fong, Omer Gilan, Enid Y.N. Lam, Alan F. Rubin, Sarah Ftouni, Dean Tyler, Kym L. Stanley, Devbarna Sinha, Paul Yeh, Jessica Morison, George Giotopoulos, Dave Lugo, Philip Jeffrey, Stanley Chun-Wei Lee, Christopher Carpenter, Richard Gregory, Robert G. Ramsay, Steven Lane, Omar Abdel‐Wahab, Tony Kouzarides, Ricky W. Johnstone, Sarah‐Jane Dawson, Brian J.P. Huntly, Rab K. Prinjha, Anthony T. Papenfuss, Mark A. Dawson - Nature 2015 cited by 548
- Targeting the adenosine 2A receptor enhances chimeric antigen receptor T cell efficacy
Authors: Paul A. Beavis, Melissa A. Henderson, Lauren Giuffrida, Jane K. Mills, Kevin Sek, Ryan Cross, Alexander J. Davenport, Liza B. John, Sherly Mardiana, Clare Y. Slaney, Ricky W. Johnstone, Joseph A. Trapani, John Stagg, Sherene Loi, Lev M. Kats, David Gyorki, Michael H. Kershaw, Phillip K. Darcy - Journal of Clinical Investigation 2017 cited by 321
- Natural Killer Cells Suppress T Cell-Associated Tumor Immune Evasion
Authors: Andrew J. Freeman, Stephin J. Vervoort, Kelly M. Ramsbottom, Madison J. Kelly, Jessica Michie, Lizzy Pijpers, Ricky W. Johnstone, Conor J. Kearney, Jane Oliaro - Cell Reports 2019 cited by 144
- Constitutive Type I Interferon Modulates Homeostatic Balance through Tonic Signaling
Authors: Daniel J. Gough, Nicole L. Messina, Christopher J. Clarke, Ricky W. Johnstone, David E. Levy - Immunity 2012 cited by 457
- Inhibition of RNA Polymerase I as a Therapeutic Strategy to Promote Cancer-Specific Activation of p53
Authors: Megan J. Bywater, Gretchen Poortinga, Elaine Sanij, Nadine Hein, Abigail Peck, Carleen Cullinane, Meaghan Wall, Leonie A. Cluse, Denis Drygin, Kenna Anderes, Nanni Huser, Chris Proffitt, Joshua Bliesath, Mustapha Haddach, Michael K. Schwaebe, David M. Ryckman, William G. Rice, Clemens A. Schmitt, Scott W. Lowe, Ricky W. Johnstone, Richard B. Pearson, Grant A. McArthur, Ross D. Hannan - Cancer Cell 2012 cited by 560
- Apoptosis
Authors: Ricky W. Johnstone, Astrid A. Ruefli, Scott W. Lowe - Cell 2002 cited by 2,243
- CDK13 cooperates with CDK12 to control global RNA polymerase II processivity
Authors: Zheng Fan, Jennifer R. Devlin, Simon J. Hogg, Maria Doyle, Paul F. Harrison, Izabela Todorovski, Leonie A. Cluse, Deborah A. Knight, Jarrod J. Sandow, Gareth P. Gregory, Andrew Fox, Traude H. Beilharz, Nicholas Kwiatkowski, Nichollas E. Scott, Ana Tufegdžić Vidaković, Gavin Kelly, Jesper Q. Svejstrup, Matthias Geyer, Nathanael S. Gray, Stephin J. Vervoort, Ricky W. Johnstone - Science Advances 2020 cited by 165
- Activation of HIV Transcription with Short-Course Vorinostat in HIV-Infected Patients on Suppressive Antiretroviral Therapy
Authors: Julian Elliott, Fiona Wightman, Ajantha Solomon, Khader Ghneim, Jeffrey D. Ahlers, Mark J. Cameron, Miranda Z. Smith, Tim Spelman, James McMahon, Pushparaj Velayudham, Gregor J. Brown, Janine Roney, Jo Watson, Miles H. Prince, Jennifer Hoy, Nicolas Chomont, Rémi Fromentin, Francesco A. Procopio, Joumana Zeidan, Sarah Palmer, Lina Odevall, Ricky W. Johnstone, Ben P. Martin, Elizabeth Sinclair, Steven G. Deeks, Daria J. Hazuda, Paul Cameron, Rafick‐Pierre Sékaly, Sharon R. Lewin - PLoS Pathogens 2014 cited by 511
- CDK4/6 Inhibition Promotes Antitumor Immunity through the Induction of T-cell Memory
Authors: Emily J. Lelliott, Isabella Y. Kong, Magnus Zethoven, Kelly M. Ramsbottom, Luciano G. Martelotto, Déborah Meyran, Joe Jiang Zhu, Matteo Costacurta, Laura Kirby, Jarrod J. Sandow, Lydia Rui Jia Lim, Pilar M. Domínguez, Izabela Todorovski, Nicole M. Haynes, Paul A. Beavis, Paul J. Neeson, Edwin D. Hawkins, Grant A. McArthur, Ian A. Parish, Ricky W. Johnstone, Jane Oliaro, Karen E. Sheppard, Conor J. Kearney, Stephin J. Vervoort - Cancer Discovery 2021 cited by 129
- Efficient CRISPR/Cas9 Gene Editing in Uncultured Naive Mouse T Cells for In Vivo Studies
Authors: Simone Nüssing, Imran G. House, Conor J. Kearney, Amanda X. Y. Chen, Stephin J. Vervoort, Paul A. Beavis, Jane Oliaro, Ricky W. Johnstone, Joseph A. Trapani, Ian A. Parish - The Journal of Immunology 2020 cited by 91
- Antigen-driven EGR2 expression is required for exhausted CD8+ T cell stability and maintenance
Authors: Mayura V. Wagle, Stephin J. Vervoort, Madison J. Kelly, Willem Van Der Byl, Timothy J. Peters, Ben P. Martin, Luciano G. Martelotto, Simone Nüssing, Kelly M. Ramsbottom, James Torpy, Deborah A. Knight, Sinead M. Reading, Kevin Thia, Lisa A. Miosge, Debbie Howard, Renee Gloury, Sarah S. Gabriel, Daniel T. Utzschneider, Jane Oliaro, Jonathan D. Powell, Fabio Luciani, Joseph A. Trapani, Ricky W. Johnstone, Axel Kallies, Christopher C. Goodnow, Ian A. Parish - Nature Communications 2021 cited by 59
