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Joseph A. Trapani

Active 1985–2025

138
Papers
25,577
Citations
91
h-index
136
i10-index

Citations

Citations per year for Joseph A. Trapani1979: 6 citations1987: 1 citations1988: 1 citations1989: 6 citations1990: 6 citations1991: 9 citations1992: 7 citations1993: 3 citations1994: 4 citations1995: 14 citations1996: 40 citations1997: 123 citations1998: 137 citations1999: 145 citations2000: 153 citations2001: 242 citations2002: 225 citations2003: 248 citations2004: 255 citations2005: 248 citations2006: 223 citations2007: 252 citations2008: 161 citations2009: 253 citations2010: 284 citations2011: 175 citations2012: 157 citations2013: 157 citations2014: 137 citations2015: 224 citations2016: 148 citations2017: 178 citations2018: 206 citations2019: 623 citations2020: 718 citations2021: 808 citations2022: 955 citations2023: 670 citations2024: 1,019 citations2025: 555 citations2026: 18 citations1980–1986: no citations, so these years are not shown

Citation sources

Countries

World map of the countries and regions citing this authorUnited States: 3,056 citing papers, 28.2% of this breakdownChina: 1,605 citing papers, 14.8% of this breakdownAustralia: 669 citing papers, 6.2% of this breakdownGermany: 609 citing papers, 5.6% of this breakdownUnited Kingdom: 543 citing papers, 5% of this breakdownCanada: 387 citing papers, 3.6% of this breakdownFrance: 378 citing papers, 3.5% of this breakdownItaly: 370 citing papers, 3.4% of this breakdownJapan: 318 citing papers, 2.9% of this breakdownNetherlands: 235 citing papers, 2.2% of this breakdownSwitzerland: 217 citing papers, 2% of this breakdownSpain: 213 citing papers, 1.9% of this breakdown
0%28.2%Other 20.7%

Institutions

Fields

  • Medicine41.5%
  • Immunology and Microbiology26.9%
  • Biochemistry, Genetics and Molecular Biology25.7%
  • Engineering1.5%
  • Neuroscience1.1%
  • Nursing1.1%
  • Other2.2%

Topics

  • Immune Cell Function and Interaction9.8%
  • CAR-T cell therapy research7.3%
  • Immunotherapy and Immune Responses5.6%
  • Cancer Immunotherapy and Biomarkers4.9%
  • T-cell and B-cell Immunology4.2%
  • Cell death mechanisms and regulation2.9%
  • Other65.3%

Coauthors

All papers

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  1. Perforin and granzymes: function, dysfunction and human pathology

    Authors: Ilia Voskoboinik, James C. Whisstock, Joseph A. Trapani - Nature reviews. Immunology 2015 cited by 1,288

  2. CMTM6 maintains the expression of PD-L1 and regulates anti-tumour immunity

    Authors: Marian L. Burr, Christina E. Sparbier, Yih-Chih Chan, James C. Williamson, Katherine Woods, Paul A. Beavis, Enid Y.N. Lam, Melissa A. Henderson, Charles C. Bell, Sabine Stolzenburg, Omer Gilan, Stuart Bloor, Tahereh Noori, David W. Morgens, Michael C. Bassik, Paul J. Neeson, Andreas Behren, Phillip K. Darcy, Sarah‐Jane Dawson, Ilia Voskoboinik, Joseph A. Trapani, Jonathan Cebon, Paul J. Lehner, Mark A. Dawson - Nature 2017 cited by 969

  3. Intratumoral Copper Modulates PD-L1 Expression and Influences Tumor Immune Evasion

    Authors: Florida Voli, Emanuele Valli, Luigi Lerra, Kathleen Kimpton, Federica Saletta, Federico M. Giorgi, Daniele Mercatelli, Jourdin R.C. Rouaen, Sylvie Shen, Jayne Murray, Aria Ahmed-Cox, Giuseppe Cirillo, Chelsea Mayoh, Paul A. Beavis, Michelle Haber, Joseph A. Trapani, Maria Kavallaris, Orazio Vittorio - Cancer Research 2020 cited by 419

  4. Tumor immune evasion arises through loss of TNF sensitivity

    Authors: Conor J. Kearney, Stephin J. Vervoort, Simon J. Hogg, Kelly M. Ramsbottom, Andrew J. Freeman, Najoua Lalaoui, Lizzy Pijpers, Jessica Michie, Kristin Brown, Deborah A. Knight, Vivien R. Sutton, Paul A. Beavis, Ilia Voskoboinik, Phillip K. Darcy, John Silke, Joseph A. Trapani, Ricky W. Johnstone, Jane Oliaro - Science Immunology 2018 cited by 393

  5. Tumor-specific cytolytic CD4 T cells mediate immunity against human cancer

    Authors: Amélie Cachot, Mariia Bilous, Yen‐Cheng Liu, Xiaokang Li, Margaux Saillard, Mara Cenerenti, Georg Alexander Rockinger, Tania Wyss, Philippe Guillaume, Julien Schmidt, Raphaël Genolet, Giuseppe Ercolano, Maria Pia Protti, Walter Reith, Kalliopi Ioannidou, Laurence de Leval, Joseph A. Trapani, George Coukos, Alexandre Harari, Daniel E. Speiser, Alexander Mathis, David Gfeller, Hatice Altug, Pedro Romero, Camilla Jandus - Science Advances 2021 cited by 320

  6. Chimeric antigen receptor T cells form nonclassical and potent immune synapses driving rapid cytotoxicity

    Authors: Alexander J. Davenport, Ryan Cross, Katherine A. Watson, Yi‐Han Liao, W. Shi, H. Miles Prince, Paul A. Beavis, Joseph A. Trapani, Michael H. Kershaw, David Ritchie, Phillip K. Darcy, Paul J. Neeson, Misty R. Jenkins - National Academy of Sciences, Proceedings of the National Academy of Sciences 2018 cited by 357

  7. Adoptive cellular therapy with T cells expressing the dendritic cell growth factor Flt3L drives epitope spreading and antitumor immunity

    Authors: Junyun Lai, Sherly Mardiana, Imran G. House, Kevin Sek, Melissa A. Henderson, Lauren Giuffrida, Amanda X. Y. Chen, Kirsten L. Todd, Emma V. Petley, Jack D. Chan, Emma M. Carrington, Andrew M. Lew, Benjamin Solomon, Joseph A. Trapani, Katherine Kedzierska, Maximilien Evrard, Stephin J. Vervoort, Jason Waithman, Phillip K. Darcy, Paul A. Beavis - Nature Immunology 2020 cited by 215

  8. Functional significance of the perforin/granzyme cell death pathway

    Authors: Joseph A. Trapani, Mark J. Smyth - Nature reviews. Immunology 2002 cited by 1,247

  9. Blockade of the co-inhibitory molecule PD-1 unleashes ILC2-dependent antitumor immunity in melanoma

    Authors: Nicolas Jacquelot, Cyril Seillet, Minyu Wang, Angela Pizzolla, Yang Liao, Soroor Hediyeh-zadeh, Sharon Grisaru‐Tal, Cynthia Louis, Qiutong Huang, Jaring Schreuder, Fernando Souza-Fonseca-Guimarães, Carolyn A. de Graaf, Kevin Thia, Sean Macdonald, Mary Camilleri, Kylie Luong, Shengbo Zhang, Michaël Chopin, Tristan Molden-Hauer, Stephen L. Nutt, Viktor Umansky, Bogoljub Ćirić, Joanna R. Groom, Paul S. Foster, Philip M. Hansbro, Andrew N. J. McKenzie, Daniel H.D. Gray, Andreas Behren, Jonathan Cebon, Éric Vivier, Ian P. Wicks, Joseph A. Trapani, Ariel Munitz, Melissa J. Davis, Wei Shi, Paul J. Neeson, Gabrielle T. Belz - Nature Immunology 2021 cited by 175

  10. ESCRT-mediated membrane repair protects tumor-derived cells against T cell attack

    Authors: Alex T. Ritter, Gleb Shtengel, C. Shan Xu, Aubrey V. Weigel, David P. Hoffman, Melanie Freeman, Nirmala Iyer, Nensi Alivodej, David Ackerman, Ilia Voskoboinik, Joseph A. Trapani, Harald F. Hess, Ira Mellman - Science 2022 cited by 131

  11. Untimely TGFβ responses in COVID-19 limit antiviral functions of NK cells

    Authors: Mario Witkowski, Caroline Tizian, Marta Ferreira‐Gomes, Daniela Niemeyer, Terry C. Jones, Frederik Heinrich, Stefan Frischbutter, Stefan Angermair, Thordis Hohnstein, Irene Mattiola, Philipp Nawrath, Sophie McEwen, Silvia Zocche, Edoardo Viviano, Gitta Anne Heinz, Marcus Maurer, Uwe Kölsch, Robert Lorenz Chua, Tom Aschman, Christian Meisel, Josefine Radke, Birgit Sawitzki, Jobst Roehmel, Kristina Allers, Verena Moos, Thomas Schneider, Leif G. Hanitsch, Marcus Mall, Christian Conrad, Helena Radbruch, Claudia U. Duerr, Joseph A. Trapani, Emanuela Marcenaro, Tilmann Kallinich, Victor M. Corman, Florian Kurth, Leif Erik Sander, Christian Drosten, Sascha Treskatsch, Pawel Durek, Andrey Kruglov, Andreas Radbruch, Mir‐Farzin Mashreghi, Andreas Diefenbach - Nature 2021 cited by 280

  12. T STEM -like CAR-T cells exhibit improved persistence and tumor control compared with conventional CAR-T cells in preclinical models

    Authors: Déborah Meyran, Joe Jiang Zhu, Jeanne Butler, Daniela Tantalo, Sean Macdonald, Thu Ngoc Nguyen, Minyu Wang, Niko Thio, Criselle D’Souza, Vicky Mengfei Qin, Clare Y. Slaney, Aaron J Harrison, Kevin Sek, Pasquale Petrone, Kevin Thia, Lauren Giuffrida, Andrew M. Scott, Rachael Terry, Ben Tran, Jayesh Desai, H. Miles Prince, Simon J. Harrison, Paul A. Beavis, Michael H. Kershaw, Benjamin Solomon, Paul G. Ekert, Joseph A. Trapani, Phillip K. Darcy, Paul J. Neeson - Science Translational Medicine 2023 cited by 97

  13. Persistence and Efficacy of Second Generation CAR T Cell Against the LeY Antigen in Acute Myeloid Leukemia

    Authors: David S. Ritchie, Paul J. Neeson, Amit Khot, Stefan Peinert, Tsin Yee Tai, Kellie M. Tainton, Karen Chen, Mandy Shin, Dominic Wall, Dirk Hönemann, Peter Gambell, David Westerman, Javier Haurat, Jennifer A. Westwood, Andrew M. Scott, L. Ya. Kravets, Michael Dickinson, Joseph A. Trapani, Mark J. Smyth, Phillip K. Darcy, Michael H. Kershaw, H. Miles Prince - Molecular Therapy 2013 cited by 433

  14. Targeting the adenosine 2A receptor enhances chimeric antigen receptor T cell efficacy

    Authors: Paul A. Beavis, Melissa A. Henderson, Lauren Giuffrida, Jane K. Mills, Kevin Sek, Ryan Cross, Alexander J. Davenport, Liza B. John, Sherly Mardiana, Clare Y. Slaney, Ricky W. Johnstone, Joseph A. Trapani, John Stagg, Sherene Loi, Lev M. Kats, David Gyorki, Michael H. Kershaw, Phillip K. Darcy - Journal of Clinical Investigation 2017 cited by 321

  15. Perforin-mediated target-cell death and immune homeostasis

    Authors: Ilia Voskoboinik, Mark J. Smyth, Joseph A. Trapani - Nature reviews. Immunology 2006 cited by 590

  16. Eprenetapopt triggers ferroptosis, inhibits NFS1 cysteine desulfurase, and synergizes with serine and glycine dietary restriction

    Authors: Kenji M. Fujihara, Bonnie Z. Zhang, Thomas D. Jackson, Moses Olalekan Ogunkola, Brunda Nijagal, Julia V. Milne, David A. Sallman, Ching‐Seng Ang, Iva Nikolić, Conor J. Kearney, Simon J. Hogg, Carlos S. Cabalag, Vivien R. Sutton, Sally V. Watt, Asuka T. Fujihara, Joseph A. Trapani, Kaylene J. Simpson, Diana Stojanovski, Silke Leimkühler, Sue Haupt, Wayne A. Phillips, Nicholas J. Clemons - Science Advances 2022 cited by 94

  17. CAR-T Cells Inflict Sequential Killing of Multiple Tumor Target Cells

    Authors: Alexander J. Davenport, Misty R. Jenkins, Ryan Cross, Carmen S. Yong, H. Miles Prince, David S. Ritchie, Joseph A. Trapani, Michael H. Kershaw, Phillip K. Darcy, Paul J. Neeson - Cancer Immunology Research 2015 cited by 148

  18. Efficient CRISPR/Cas9 Gene Editing in Uncultured Naive Mouse T Cells for In Vivo Studies

    Authors: Simone Nüssing, Imran G. House, Conor J. Kearney, Amanda X. Y. Chen, Stephin J. Vervoort, Paul A. Beavis, Jane Oliaro, Ricky W. Johnstone, Joseph A. Trapani, Ian A. Parish - The Journal of Immunology 2020 cited by 91

  19. Antigen-driven EGR2 expression is required for exhausted CD8+ T cell stability and maintenance

    Authors: Mayura V. Wagle, Stephin J. Vervoort, Madison J. Kelly, Willem Van Der Byl, Timothy J. Peters, Ben P. Martin, Luciano G. Martelotto, Simone Nüssing, Kelly M. Ramsbottom, James Torpy, Deborah A. Knight, Sinead M. Reading, Kevin Thia, Lisa A. Miosge, Debbie Howard, Renee Gloury, Sarah S. Gabriel, Daniel T. Utzschneider, Jane Oliaro, Jonathan D. Powell, Fabio Luciani, Joseph A. Trapani, Ricky W. Johnstone, Axel Kallies, Christopher C. Goodnow, Ian A. Parish - Nature Communications 2021 cited by 59

  20. Therapeutic strategies to remodel immunologically cold tumors

    Authors: Minyu Wang, Sen Wang, Jayesh Desai, Joseph A. Trapani, Paul J. Neeson - Clinical & Translational Immunology 2020 cited by 80

  21. Failed CTL/NK cell killing and cytokine hypersecretion are directly linked through prolonged synapse time

    Authors: Misty R. Jenkins, Jesse A. Rudd-Schmidt, Jamie A. Lopez, Kelly M. Ramsbottom, Stuart I. Mannering, Daniel M. Andrews, Ilia Voskoboinik, Joseph A. Trapani - The Journal of Experimental Medicine 2015 cited by 254

  22. Perforin forms transient pores on the target cell plasma membrane to facilitate rapid access of granzymes during killer cell attack

    Authors: Jamie A. Lopez, Olivia Susanto, Misty R. Jenkins, Natalya Lukoyanova, Vivien R. Sutton, Ruby H. P. Law, Angus P. R. Johnston, Catherina H. Bird, Phillip I. Bird, James C. Whisstock, Joseph A. Trapani, Helen R. Saibil, Ilia Voskoboinik - Blood 2013 cited by 251

  23. SUGAR-seq enables simultaneous detection of glycans, epitopes, and the transcriptome in single cells

    Authors: Conor J. Kearney, Stephin J. Vervoort, Kelly M. Ramsbottom, Izabela Todorovski, Emily J. Lelliott, Magnus Zethoven, Lizzy Pijpers, Ben P. Martin, Timothy Semple, Luciano G. Martelotto, Joseph A. Trapani, Ian A. Parish, Nichollas E. Scott, Jane Oliaro, Ricky W. Johnstone - Science Advances 2021 cited by 84

  24. Low-dose carboplatin modifies the tumor microenvironment to augment CAR T cell efficacy in human prostate cancer models

    Authors: L. H. Porter, Joe Jiang Zhu, Natalie L. Lister, Sarah Harrison, Shivakumar Keerthikumar, D. L. Goode, Rosalía Quezada Urban, D.J. Byrne, Arun Azad, Ian Vela, Michael S. Hofman, Paul J. Neeson, Phillip K. Darcy, Joseph A. Trapani, Renea A. Taylor, Gail P. Risbridger - Nature Communications 2023 cited by 44