Jonathan D. Powell
Active 1988–2025
- 89
- Papers
- 23,015
- Citations
- 74
- h-index
- 89
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Medicine39.5%
- Biochemistry, Genetics and Molecular Biology27.2%
- Immunology and Microbiology27%
- Neuroscience2.5%
- Engineering1.7%
- Materials Science0.5%
- Other1.6%
Topics
- Immune Cell Function and Interaction9.7%
- T-cell and B-cell Immunology5.6%
- Cancer Immunotherapy and Biomarkers4.5%
- Immune cells in cancer4.4%
- Immunotherapy and Immune Responses3.6%
- Cancer, Hypoxia, and Metabolism3.5%
- Other68.7%
Coauthors
- Maureen R. Horton16
- Chirag H. Patel15
- Im‐Hong Sun12
- Liang Zhao12
- Min Hee Oh11
- Elizabeth A. Thompson10
- Robert D. Leone10
- Greg M. Delgoffe9
- Jiayu Wen9
- Samuel L. Collins9
- Drew M. Pardoll8
- Kristen Pollizzi8
- Ada Tam7
- Barbara S. Slusher7
- Leo Luznik7
- Adam T. Waickman6
- Im-Meng Sun6
- Jesse Alt6
- Rana Rais6
- Richard J. Jones6
- Alvaro A. Ordoñez5
- Carol Ann Huff5
- Ephraim J. Fuchs5
- Franco R. D’Alessio5
All papers
- Glutamine blockade induces divergent metabolic programs to overcome tumor immune evasion
Authors: Robert D. Leone, Liang Zhao, Judson M. Englert, Im-Meng Sun, Min Hee Oh, Im‐Hong Sun, Matthew L. Arwood, Ian A. Bettencourt, Chirag H. Patel, Jiayu Wen, Ada Tam, Richard L. Blosser, Eva Prchalová, Jesse Alt, Rana Rais, Barbara S. Slusher, Jonathan D. Powell - Science 2019 cited by 1,177
- Metabolism of immune cells in cancer
Authors: Robert D. Leone, Jonathan D. Powell - Nature reviews. Cancer 2020 cited by 864
- Targeting glutamine metabolism enhances tumor-specific immunity by modulating suppressive myeloid cells
Authors: Min Hee Oh, Im‐Hong Sun, Liang Zhao, Robert D. Leone, Im-Meng Sun, Wei Xu, Samuel L. Collins, Ada Tam, Richard L. Blosser, Chirag H. Patel, Judson M. Englert, Matthew L. Arwood, Jiayu Wen, Yee Chan‐Li, Lukáš Tenora, Pavel Majer, Rana Rais, Barbara S. Slusher, Maureen R. Horton, Jonathan D. Powell - Journal of Clinical Investigation 2020 cited by 433
- HLA-Haploidentical Bone Marrow Transplantation for Hematologic Malignancies Using Nonmyeloablative Conditioning and High-Dose, Posttransplantation Cyclophosphamide
Authors: Leo Luznik, Paul V. O’Donnell, Heather J. Symons, Allen Chen, M. Susan Leffell, Marianna Zahurak, Ted Gooley, S Piantadosi, Michele Kaup, Richard F. Ambinder, Carol Ann Huff, William Matsui, Javier Bolaños‐Meade, Ivan Borrello, Jonathan D. Powell, Elizabeth B. Harrington, S. Warnock, Mary E.D. Flowers, Robert A. Brodsky, Brenda M. Sandmaier, Rainer Storb, Richard J. Jones, Ephraim J. Fuchs - Biology of Blood and Marrow Transplantation 2008 cited by 1,906
- Role of LAG-3 in Regulatory T Cells
Authors: Ching-Tai Huang, Creg J. Workman, Dallas B. Flies, Xiaoyu Pan, Aimee L. Marson, Gang Zhou, Edward L. Hipkiss, Sowmya Ravi, Jeanne Kowalski, Hyam I. Levitsky, Jonathan D. Powell, Drew M. Pardoll, Charles G. Drake, Dario A.A. Vignali - Immunity 2004 cited by 1,299
- Developing a pro-regenerative biomaterial scaffold microenvironment requires T helper 2 cells
Authors: Kaitlyn Sadtler, Kenneth Estrellas, Brian W. Allen, Matthew T. Wolf, Hongni Fan, Ada Tam, Chirag H. Patel, Brandon Luber, Hao Wang, Kathryn R. Wagner, Jonathan D. Powell, Franck Housseau, Drew M. Pardoll, Jennifer H. Elisseeff - Science 2016 cited by 632
- The mTOR Kinase Differentially Regulates Effector and Regulatory T Cell Lineage Commitment
Authors: Greg M. Delgoffe, Thomas P. Kole, Yan Zheng, Paul E. Zarek, Krystal Matthews, Bo Xiao, Paul F. Worley, Sara C. Kozma, Jonathan D. Powell - Immunity 2009 cited by 1,259
- Immune dysregulation as a driver of idiopathic pulmonary fibrosis
Authors: Kevin Shenderov, Samuel L. Collins, Jonathan D. Powell, Maureen R. Horton - Journal of Clinical Investigation 2021 cited by 293
- Regulation of Immune Responses by mTOR
Authors: Jonathan D. Powell, Kristen Pollizzi, Emily Heikamp, Maureen R. Horton - Annual Review of Immunology 2012 cited by 820
- An engineered IL-2 partial agonist promotes CD8+ T cell stemness
Authors: Fei Mo, Zhiya Yu, Peng Li, Jangsuk Oh, Rosanne Spolski, Liang Zhao, Caleb R. Glassman, Tori N. Yamamoto, Yun Chen, Filip Gołębiowski, Dalton Hermans, Sonia Majri-Morrison, Lora K. Picton, Wei Liao, Min Ren, Xiaoxuan Zhuang, Suman Mitra, Jian-Xin Lin, Luca Gattinoni, Jonathan D. Powell, Nicholas P. Restifo, K. Christopher García, Warren J. Leonard - Nature 2021 cited by 177
- Discovery of DRP-104, a tumor-targeted metabolic inhibitor prodrug
Authors: Rana Rais, Kathryn M. Lemberg, Lukáš Tenora, Matthew L. Arwood, Arindom Pal, Jesse Alt, Ying Wu, Jenny Lam, Joanna Marie H. Aguilar, Liang Zhao, Diane E. Peters, Carolyn Tallon, Rajeev Pandey, Ajit G. Thomas, Ranjeet Prasad Dash, Tanguy Y. Seiwert, Pavel Majer, Robert D. Leone, Jonathan D. Powell, Barbara S. Slusher - Science Advances 2022 cited by 124
- Targeting metabolism to regulate immune responses in autoimmunity and cancer
Authors: Chirag H. Patel, Robert D. Leone, Maureen R. Horton, Jonathan D. Powell - Nature Reviews Drug Discovery 2019 cited by 319
- The kinase mTOR regulates the differentiation of helper T cells through the selective activation of signaling by mTORC1 and mTORC2
Authors: Greg M. Delgoffe, Kristen Pollizzi, Adam T. Waickman, Emily Heikamp, David J. Meyers, Maureen R. Horton, Bo Xiao, Paul F. Worley, Jonathan D. Powell - Nature Immunology 2011 cited by 1,093
- mTORC1 and mTORC2 selectively regulate CD8+ T cell differentiation
Authors: Kristen Pollizzi, Chirag H. Patel, Im‐Hong Sun, Min Hee Oh, Adam T. Waickman, Jiayu Wen, Greg M. Delgoffe, Jonathan D. Powell - Journal of Clinical Investigation 2015 cited by 408
- Leucine Metabolism in T Cell Activation: mTOR Signaling and Beyond
Authors: Elitsa Ananieva, Jonathan D. Powell, Susan M. Hutson - Advances in Nutrition 2016 cited by 191
- Inhibition of the adenosine A2a receptor modulates expression of T cell coinhibitory receptors and improves effector function for enhanced checkpoint blockade and ACT in murine cancer models
Authors: Robert D. Leone, Im-Meng Sun, Min Hee Oh, Im‐Hong Sun, Jiayu Wen, Judson M. Englert, Jonathan D. Powell - Cancer Immunology Immunotherapy 2018 cited by 186
- mTOR, metabolism, and the regulation of T‐cell differentiation and function
Authors: Adam T. Waickman, Jonathan D. Powell - Immunological Reviews 2012 cited by 413
- Acid Suspends the Circadian Clock in Hypoxia through Inhibition of mTOR
Authors: Zandra E. Walton, Chirag H. Patel, Rebekah Brooks, Yongjun Yu, Arig Ibrahim‐Hashim, Malini Riddle, Alessandra Porcu, Tianying Jiang, Brett L. Ecker, Feven Tameire, Constantinos Koumenis, Ashani T. Weeraratna, David K. Welsh, Robert J. Gillies, James C. Alwine, Lin Zhang, Jonathan D. Powell, Chi V. Dang - Cell 2018 cited by 235
- Hyaluronan Fragments Act as an Endogenous Danger Signal by Engaging TLR2
Authors: Kara Scheibner, Michael A. Lutz, Sada Boodoo, Matthew J. Fenton, Jonathan D. Powell, Maureen R. Horton - The Journal of Immunology 2006 cited by 698
- RETRACTED ARTICLE: Re-engineered BCG overexpressing cyclic di-AMP augments trained immunity and exhibits improved efficacy against bladder cancer
Authors: Alok Kumar Singh, Monali Praharaj, Kara A. Lombardo, Takahiro Yoshida, Andrés Matoso, Alex S. Baras, Liang Zhao, Geetha Srikrishna, Joy Huang, Pankaj Prasad, Jonathan D. Powell, Max Kates, David J. McConkey, Drew M. Pardoll, William R. Bishai, Trinity J. Bivalacqua - Nature Communications 2022 cited by 97
- Antigen-driven EGR2 expression is required for exhausted CD8+ T cell stability and maintenance
Authors: Mayura V. Wagle, Stephin J. Vervoort, Madison J. Kelly, Willem Van Der Byl, Timothy J. Peters, Ben P. Martin, Luciano G. Martelotto, Simone Nüssing, Kelly M. Ramsbottom, James Torpy, Deborah A. Knight, Sinead M. Reading, Kevin Thia, Lisa A. Miosge, Debbie Howard, Renee Gloury, Sarah S. Gabriel, Daniel T. Utzschneider, Jane Oliaro, Jonathan D. Powell, Fabio Luciani, Joseph A. Trapani, Ricky W. Johnstone, Axel Kallies, Christopher C. Goodnow, Ian A. Parish - Nature Communications 2021 cited by 59
- Nonmyeloablative HLA-Matched Sibling Allogeneic Hematopoietic Stem Cell Transplantation for Severe Sickle Cell Phenotype
Authors: Matthew M. Hsieh, Courtney D. Fitzhugh, R. Patrick Weitzel, Mary E. Link, Wynona Coles, Xiongce Zhao, Griffin P. Rodgers, Jonathan D. Powell, John F. Tisdale - JAMA 2014 cited by 346
- Inhibition of the Adenosine Pathway to Potentiate Cancer Immunotherapy: Potential for Combinatorial Approaches
Authors: Elizabeth Thompson, Jonathan D. Powell - Annual Review of Medicine 2020 cited by 76
- A2A receptor signaling promotes peripheral tolerance by inducing T-cell anergy and the generation of adaptive regulatory T cells
Authors: Paul E. Zarek, Ching-Tai Huang, Eric R. Lutz, Jeanne Kowalski, Maureen R. Horton, Joel Linden, Charles G. Drake, Jonathan D. Powell - Blood 2007 cited by 498
