Mark A. Dawson
Active 1999–2025
- 78
- Papers
- 17,907
- Citations
- 52
- h-index
- 75
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Biochemistry, Genetics and Molecular Biology57.5%
- Medicine31.2%
- Immunology and Microbiology5.6%
- Agricultural and Biological Sciences1.2%
- Chemistry1.1%
- Engineering0.8%
- Other2.6%
Topics
- Epigenetics and DNA Methylation7.6%
- Protein Degradation and Inhibitors6.7%
- Histone Deacetylase Inhibitors Research4.4%
- RNA modifications and cancer4%
- Ubiquitin and proteasome pathways3%
- Cancer-related gene regulation2.9%
- Other71.4%
Coauthors
- Enid Y.N. Lam25
- Sarah‐Jane Dawson23
- Yih-Chih Chan20
- Omer Gilan15
- Charles C. Bell13
- Laura MacPherson11
- Rab K. Prinjha11
- Dane Vassiliadis10
- Marian L. Burr9
- Paul Yeh9
- Sarah Ftouni9
- Tony Kouzarides9
- Kathy Knezevic8
- Katie Fennell8
- Andrea Gillespie7
- Brian J.P. Huntly7
- Ricky W. Johnstone7
- Stephen Q. Wong7
- Andrew J. Bannister6
- Chun Yew Fong6
- Miriam M. Yeung6
- Paola Grandi6
- Anthony T. Papenfuss5
- Constantine S. Tam5
All papers
- Cancer Epigenetics: From Mechanism to Therapy
Authors: Mark A. Dawson, Tony Kouzarides - Cell 2012 cited by 3,240
- Targeting the epigenetic regulation of antitumour immunity
Authors: Simon J. Hogg, Paul A. Beavis, Mark A. Dawson, Ricky W. Johnstone - Nature Reviews Drug Discovery 2020 cited by 620
- Non-genetic mechanisms of therapeutic resistance in cancer
Authors: Jean‐Christophe Marine, Sarah‐Jane Dawson, Mark A. Dawson - Nature reviews. Cancer 2020 cited by 615
- An Evolutionarily Conserved Function of Polycomb Silences the MHC Class I Antigen Presentation Pathway and Enables Immune Evasion in Cancer
Authors: Marian L. Burr, Christina E. Sparbier, Kah Lok Chan, Yih-Chih Chan, Ariena Kersbergen, Enid Y.N. Lam, Elizabeth Azidis-Yates, Dane Vassiliadis, Charles C. Bell, Omer Gilan, Susan Jackson, Lavinia Tan, Stephen Q. Wong, Sebastian Hollizeck, Ewa M. Michalak, Hannah V. Siddle, Michael T. McCabe, Rab K. Prinjha, Glen Guerra, Benjamin Solomon, Shahneen Sandhu, Sarah‐Jane Dawson, Paul A. Beavis, Richard W. Tothill, Carleen Cullinane, Paul J. Lehner, Kate D. Sutherland, Mark A. Dawson - Cancer Cell 2019 cited by 642
- A druggable copper-signalling pathway that drives inflammation
Authors: Stéphanie Solier, Sebastian Müller, Tatiana Cañeque, Antoine Versini, Arnaud Mansart, Fabien Sindikubwabo, Leeroy Baron, Laila Emam, Pierre Gestraud, G. Dan Pantoş, Vincent Gandon, Christine Gaillet, Ting‐Di Wu, Florent Dingli, Damarys Loew, Sylvain Baulande, Sylvère Durand, Valentin Sencio, Cyril Robil, François Trottein, David Péricat, Emmanuelle Näser, Céline Cougoule, Étienne Meunier, Anne-Laure Bègue, Hélène Salmon, Nicolas Manel, Alain Puisieux, Sarah Watson, Mark A. Dawson, Nicolas Servant, Guido Kroemer, Djillali Annane, Raphaël Rodriguez - Nature 2023 cited by 311
- CMTM6 maintains the expression of PD-L1 and regulates anti-tumour immunity
Authors: Marian L. Burr, Christina E. Sparbier, Yih-Chih Chan, James C. Williamson, Katherine Woods, Paul A. Beavis, Enid Y.N. Lam, Melissa A. Henderson, Charles C. Bell, Sabine Stolzenburg, Omer Gilan, Stuart Bloor, Tahereh Noori, David W. Morgens, Michael C. Bassik, Paul J. Neeson, Andreas Behren, Phillip K. Darcy, Sarah‐Jane Dawson, Ilia Voskoboinik, Joseph A. Trapani, Jonathan Cebon, Paul J. Lehner, Mark A. Dawson - Nature 2017 cited by 969
- The roles of DNA, RNA and histone methylation in ageing and cancer
Authors: Ewa M. Michalak, Marian L. Burr, Andrew J. Bannister, Mark A. Dawson - Nature Reviews Molecular Cell Biology 2019 cited by 585
- Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia
Authors: Mark A. Dawson, Rab K. Prinjha, Antje Dittmann, George Giotopoulos, Marcus Bantscheff, Wai-In Chan, Samuel C. Robson, Chun‐wa Chung, Carsten Hopf, Mikhail M. Savitski, Carola Huthmacher, Emma Gudgin, Dave Lugo, Sören Beinke, Trevor Chapman, Emma J. Roberts, Peter E. Soden, Kurt R. Auger, Olivier Mirguet, Konstanze Doehner, Ruud Delwel, Alan K. Burnett, Philip D. Jeffrey, Gerard Drewes, Kevin Lee, Brian J.P. Huntly, Tony Kouzarides - Nature 2011 cited by 1,532
- Selective targeting of BD1 and BD2 of the BET proteins in cancer and immunoinflammation
Authors: Omer Gilan, Inmaculada Rioja, Kathy Knezevic, Matthew Bell, Miriam M. Yeung, Nicola Harker, Enid Y.N. Lam, Chun‐wa Chung, Paul Bamborough, M. Petretich, Marjeta Urh, Stephen J. Atkinson, Anna K. Bassil, Emma J. Roberts, Dane Vassiliadis, Marian L. Burr, Alex Preston, Christopher R. Wellaway, Thilo Werner, James R. Gray, Anne‐Marie Michon, Thomas Gobbetti, Vinod Kumar, Peter E. Soden, Andrea Haynes, Johanna Vappiani, David F. Tough, S. Taylor, Sarah‐Jane Dawson, Marcus Bantscheff, Matthew Lindon, Gerard Drewes, Emmanuel H. Demont, Danette L. Daniels, Paola Grandi, Rab K. Prinjha, Mark A. Dawson - Science 2020 cited by 428
- Inhibition of METTL3 Results in a Cell-Intrinsic Interferon Response That Enhances Antitumor Immunity
Authors: Andrew A. Guirguis, Yaara Ofir-Rosenfeld, Kathy Knezevic, Wesley Blackaby, David Hardick, Yih-Chih Chan, Ali Motazedian, Andrea Gillespie, Dane Vassiliadis, Enid Y.N. Lam, Kevin Tran, Byron Andrews, Michael E. Harbour, Lina Vasiliauskaitė, Claire J. Saunders, Georgia Tsagkogeorga, Aleksandra Azevedo, Joanna Obacz, Ewa S. Pilka, Marie Carkill, Laura MacPherson, Elanor N. Wainwright, Brian Liddicoat, Benjamin J. Blyth, Mark R. Albertella, Oliver Rausch, Mark A. Dawson - Cancer Discovery 2023 cited by 115
- Prediction and monitoring of relapse in stage III melanoma using circulating tumor DNA
Authors: Lavinia Tan, Shahneen Sandhu, Rebecca Lee, James Li, Jason Callahan, Sarah Ftouni, Nathalie Dhomen, Philippa Middlehurst, Andrea Wallace, Jeanette Raleigh, Athena Hatzimihalis, Michael A. Henderson, Mark Shackleton, Andrew Haydon, Victoria Mar, David Gyorki, D. Oudit, Mark A. Dawson, Rodney J. Hicks, Paul Lorigan, Grant A. McArthur, Richard Marais, Stephen Q. Wong, Sarah‐Jane Dawson - Annals of Oncology 2019 cited by 190
- Epigenetic silencing by the HUSH complex mediates position-effect variegation in human cells
Authors: Iva A. Tchasovnikarova, Richard T. Timms, Nicholas J. Matheson, Kim Wals, Robin Antrobus, Berthold Göttgens, Gordon Dougan, Mark A. Dawson, Paul J. Lehner - Science 2015 cited by 372
- Non-genetic determinants of malignant clonal fitness at single-cell resolution
Authors: Katie Fennell, Dane Vassiliadis, Enid Y.N. Lam, Luciano G. Martelotto, Jesse J. Balic, Sebastian Hollizeck, Tom Weber, Timothy Semple, Qing Wang, Denise C. Miles, Laura MacPherson, Yih-Chih Chan, Andrew A. Guirguis, Lev M. Kats, Emily Wong, Sarah‐Jane Dawson, Shalin H. Naik, Mark A. Dawson - Nature 2021 cited by 160
- HBO1 is required for the maintenance of leukaemia stem cells
Authors: Laura MacPherson, Juliana Anokye, Miriam M. Yeung, Enid Y.N. Lam, Yih-Chih Chan, Chen-Fang Weng, Paul Yeh, Kathy Knezevic, Miriam Butler, Annabelle Hoegl, Kah Lok Chan, Marian L. Burr, Linden J. Gearing, Tracy A. Willson, Joy Liu, Jarny Choi, Yuqing Yang, Rebecca A. Bilardi, Hendrik Falk, Nghi Nguyen, Paul A. Stupple, Thomas S. Peat, Ming Zhang, Melanie de Silva, Catalina Carrasco‐Pozo, Vicky M. Avery, Poh Sim Khoo, Olan Dolezal, Matthew L. Dennis, Stewart D. Nuttall, Regina Surjadi, Janet Newman, Bin Ren, David J. Leaver, Yuxin Sun, Jonathan B. Baell, Oliver M. Dovey, George S. Vassiliou, Florian Grebien, Sarah‐Jane Dawson, Ian P. Street, Brendon J. Monahan, Christopher J. Burns, Chunaram Choudhary, Marnie E. Blewitt, Anne K. Voss, Tim Thomas, Mark A. Dawson - Nature 2019 cited by 174
- BET inhibitor resistance emerges from leukaemia stem cells
Authors: Chun Yew Fong, Omer Gilan, Enid Y.N. Lam, Alan F. Rubin, Sarah Ftouni, Dean Tyler, Kym L. Stanley, Devbarna Sinha, Paul Yeh, Jessica Morison, George Giotopoulos, Dave Lugo, Philip Jeffrey, Stanley Chun-Wei Lee, Christopher Carpenter, Richard Gregory, Robert G. Ramsay, Steven Lane, Omar Abdel‐Wahab, Tony Kouzarides, Ricky W. Johnstone, Sarah‐Jane Dawson, Brian J.P. Huntly, Rab K. Prinjha, Anthony T. Papenfuss, Mark A. Dawson - Nature 2015 cited by 548
- The Epigenetic Hallmarks of Cancer
Authors: Manel Esteller, Mark A. Dawson, Cigall Kadoch, Feyruz V. Rassool, Peter A. Jones, Stephen B. Baylin - Cancer Discovery 2024 cited by 133
- The cancer epigenome: Concepts, challenges, and therapeutic opportunities
Authors: Mark A. Dawson - Science 2017 cited by 380
- Discovery of a highly potent, selective, orally bioavailable inhibitor of KAT6A/B histone acetyltransferases with efficacy against KAT6A-high ER+ breast cancer
Authors: Shikhar Sharma, Chi‐Yeh Chung, Sean Uryu, Jelena Petrovic, Joan Cao, Amanda J. Rickard, Nataliya Nady, S.E. Greasley, Eric F. Johnson, Oleg Brodsky, Showkhin Khan, Hui Wang, Zhenxiong Wang, Yong Zhang, Konstantinos Tsaparikos, Lei Chen, Anthony Mazurek, John D. Lapek, Pei‐Pei Kung, Scott C. Sutton, Paul Richardson, Eric C. Greenwald, Shinji Yamazaki, Rhys Jones, Karen A. Maegley, Patrick Bingham, Hieu Lam, Alexandra E. Stupple, Aileen Kamal, Anderly C. Chüeh, Anthony N. Cuzzupe, Benjamin J. Morrow, Bin Ren, Catalina Carrasco‐Pozo, Chin Wee Tan, Dharmesh D. Bhuva, Elizabeth Allan, Elliot Surgenor, François Vaillant, Havva Pehlivanoglu, Hendrik Falk, James R. Whittle, Janet Newman, Joseph Cursons, Judy P. Doherty, Karen L. White, Laura MacPherson, Mark Devlin, Matthew L. Dennis, Meghan Hattarki, Melanie de Silva, Michelle A. Camerino, Miriam Butler, Olan Dolezal, Patricia A. Pilling, Richard C. Foitzik, Paul A. Stupple, H. Rachel Lagiakos, Scott R. Walker, Soroor Hediyeh-zadeh, Stewart D. Nuttall, Sukhdeep K. Spall, Susan A. Charman, Theresa Connor, Thomas S. Peat, Vicky M. Avery, Ylva E. Bozikis, Yuqing Yang, Ming Zhang, Brendon J. Monahan, Anne K. Voss, Tim Thomas, Ian P. Street, Sarah‐Jane Dawson, Mark A. Dawson, Geoffrey J. Lindeman, Melissa J. Davis, Jane E. Visvader, Thomas A. Paul - Cell chemical biology 2023 cited by 69
- TET2 and TET3 regulate GlcNAcylation and H3K4 methylation through OGT and SET1/COMPASS
Authors: Rachel Deplus, Benjamin Delatte, Marie K. Schwinn, Matthieu Defrance, Jacqui Méndez, Nancy E. Murphy, Mark A. Dawson, Michael Volkmar, Pascale Putmans, Emilie Calonne, Alan H. Shih, Ross L. Levine, Olivier Bernard, Thomas Mercher, Éric Solary, Marjeta Urh, Danette L. Daniels, François Fuks - The EMBO Journal 2013 cited by 489
- Dynamic molecular monitoring reveals that SWI–SNF mutations mediate resistance to ibrutinib plus venetoclax in mantle cell lymphoma
Authors: Rishu Agarwal, Yih-Chih Chan, Constantine S. Tam, Tane Hunter, Dane Vassiliadis, Charis E. Teh, Rachel Thijssen, Paul Yeh, Stephen Q. Wong, Sarah Ftouni, Enid Y.N. Lam, Mary Ann Anderson, Christiane Pott, Omer Gilan, Charles C. Bell, Kathy Knezevic, Piers Blombery, Kathleen C. Rayeroux, Adrian Zordan, Jason Li, David C.S. Huang, Meaghan Wall, John F. Seymour, Daniel H.D. Gray, Andrew W. Roberts, Mark A. Dawson, Sarah‐Jane Dawson - Nature Medicine 2018 cited by 204
- Endogenous retroviruses are a source of enhancers with oncogenic potential in acute myeloid leukaemia
Authors: Özgen Deniz, Mamataz Ahmed, Christopher D Todd, Ana Rio‐Machín, Mark A. Dawson, Miguel R. Branco - Nature Communications 2020 cited by 149
- Targeting enhancer switching overcomes non-genetic drug resistance in acute myeloid leukaemia
Authors: Charles C. Bell, Katie Fennell, Yih-Chih Chan, Florian Rambow, Miriam M. Yeung, Dane Vassiliadis, Luis E. Lara Gonzalez, Paul Yeh, Luciano G. Martelotto, Aljosja Rogiers, Brandon E. Kremer, Olena Barbash, Helai P. Mohammad, Timothy M. Johanson, Marian L. Burr, Arindam Dhar, Natalie O. Karpinich, Luyi Tian, Dean Tyler, Laura MacPherson, Junwei Shi, Nathan Pinnawala, Chun Yew Fong, Anthony T. Papenfuss, Sean M. Grimmond, Sarah‐Jane Dawson, Rhys S. Allan, Ryan G. Kruger, Christopher R. Vakoc, David L. Goode, Shalin H. Naik, Omer Gilan, Enid Y.N. Lam, Jean‐Christophe Marine, Rab K. Prinjha, Mark A. Dawson - Nature Communications 2019 cited by 180
- CDK4/6 inhibition reprograms the breast cancer enhancer landscape by stimulating AP-1 transcriptional activity
Authors: April C. Watt, Paloma Cejas, Molly J. DeCristo, Otto Metzger, Enid Y.N. Lam, Xintao Qiu, Haley BrinJones, Nikolas Kesten, Rhiannon Coulson, Alba Font‐Tello, Klothilda Lim, Raga Vadhi, Veerle W. Daniëls, Joan Montero, Len Taing, Clifford A. Meyer, Omer Gilan, Charles C. Bell, Keegan Korthauer, Claudia Giambartolomei, Bogdan Paşaniuc, Ji-Heui Seo, Matthew L. Freedman, X. Cynthia, Matthew J. Ellis, Ian E. Krop, Eric P. Winer, Anthony Letai, Myles Brown, Mark A. Dawson, Henry W. Long, Jean J. Zhao, Shom Goel - Nature Cancer 2020 cited by 110
- Targeting Menin disrupts the KMT2A/B and polycomb balance to paradoxically activate bivalent genes
Authors: Christina E. Sparbier, Andrea Gillespie, Juliana Gomez, Nishi Kumari, Ali Motazedian, Kah Lok Chan, Charles C. Bell, Omer Gilan, Yih-Chih Chan, Sarah Popp, Daniel J. Gough, Mélanie Eckersley-Maslin, Sarah‐Jane Dawson, Paul J. Lehner, Kate D. Sutherland, Patricia Ernst, Gerard M. McGeehan, Enid Y.N. Lam, Marian L. Burr, Mark A. Dawson - Nature Cell Biology 2023 cited by 36
