Andrew Bowie
Active 1952–2025
- 83
- Papers
- 23,791
- Citations
- 62
- h-index
- 82
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Immunology and Microbiology44%
- Biochemistry, Genetics and Molecular Biology23%
- Medicine22.7%
- Neuroscience3.3%
- Agricultural and Biological Sciences2.6%
- Nursing1.1%
- Other3.3%
Topics
- Immune Response and Inflammation10.4%
- interferon and immune responses10%
- Inflammasome and immune disorders4.5%
- Immune Cell Function and Interaction2.8%
- NF-κB Signaling Pathways2.6%
- Viral Infections and Vectors2.4%
- Other67.3%
Coauthors
- Luke O'neill14
- Katherine A. Fitzgerald12
- Michael Carty11
- Leonie Unterholzner10
- Marcin Baran8
- Søren R. Paludan7
- Ismar R. Haga6
- Martina Schröder6
- Dympna J. Connolly5
- Geoffrey L. Smith5
- Ryoichi Sugisawa5
- Coralie Guy4
- Ed C. Lavelle4
- Gareth Brady4
- Geraldine Maloney4
- Julianne Stack4
- Katharine A. Shanahan4
- Natalia Muñoz‐Wolf4
- Ciara Doran3
- Eicke Latz3
- Jesper Melchjorsen3
- Kristy Horan3
- Sinéad E. Keating3
- Aisling Dunne2
All papers
- Non-canonical Activation of the DNA Sensing Adaptor STING by ATM and IFI16 Mediates NF-κB Signaling after Nuclear DNA Damage
Authors: Gillian Dunphy, Sinéad Flannery, Jessica F. Almine, Dympna J. Connolly, Christina Paulus, Kasper L. Jønsson, Martin R. Jakobsen, Michael Nevels, Andrew Bowie, Leonie Unterholzner - Molecular Cell 2018 cited by 655
- The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling
Authors: Luke O'neill, Andrew Bowie - Nature reviews. Immunology 2007 cited by 2,628
- The history of Toll-like receptors — redefining innate immunity
Authors: Luke O'neill, Douglas T. Golenbock, Andrew Bowie - Nature reviews. Immunology 2013 cited by 1,700
- The Vaccine Adjuvant Chitosan Promotes Cellular Immunity via DNA Sensor cGAS-STING-Dependent Induction of Type I Interferons
Authors: Elizabeth C. Carroll, Lei Jin, Andrés Mori, Natalia Muñoz‐Wolf, Ewa Oleszycka, Hannah B.T. Moran, Samira Mansouri, Craig P. McEntee, Eimear M. Lambe, Else Marie Agger, Peter Andersen, Colm Cunningham, Paul J. Hertzog, Katherine A. Fitzgerald, Andrew Bowie, Ed C. Lavelle - Immunity 2016 cited by 585
- IFI16 is an innate immune sensor for intracellular DNA
Authors: Leonie Unterholzner, Sinéad E. Keating, Marcin Baran, Kristy Horan, Søren B. Jensen, Shruti Sharma, Cherilyn M. Sirois, Tengchuan Jin, Eicke Latz, Tsan Sam Xiao, Katherine A. Fitzgerald, Søren R. Paludan, Andrew Bowie - Nature Immunology 2010 cited by 1,632
- Detection of Viral Infections by Innate Immunity
Authors: Michael Carty, Coralie Guy, Andrew Bowie - Biochemical Pharmacology 2020 cited by 383
- Structures of the HIN Domain:DNA Complexes Reveal Ligand Binding and Activation Mechanisms of the AIM2 Inflammasome and IFI16 Receptor
Authors: Tengchuan Jin, Andrew Perry, Jiansheng Jiang, Patrick Smith, James A. Curry, Leonie Unterholzner, Zhaozhao Jiang, Gábor Horváth, Vijay Rathinam, Ricky W. Johnstone, Veit Hornung, Eicke Latz, Andrew Bowie, Katherine A. Fitzgerald, Tsan Sam Xiao - Immunity 2012 cited by 560
- Viral evasion and subversion of pattern-recognition receptor signalling
Authors: Andrew Bowie, Leonie Unterholzner - Nature reviews. Immunology 2008 cited by 746
- Immune Sensing of DNA
Authors: Søren R. Paludan, Andrew Bowie - Immunity 2013 cited by 745
- IFI16 and cGAS cooperate in the activation of STING during DNA sensing in human keratinocytes
Authors: Jessica F. Almine, Craig O'Hare, Gillian Dunphy, Ismar R. Haga, Rangeetha J. Naik, Abdelmadjid Atrih, Dympna J. Connolly, Jordan S. Taylor, Ian R. Kelsall, Andrew Bowie, Philippa M. Beard, Leonie Unterholzner - Nature Communications 2017 cited by 343
- Cell Survival and Cytokine Release after Inflammasome Activation Is Regulated by the Toll-IL-1R Protein SARM
Authors: Michael Carty, Jay Kearney, Katharine A. Shanahan, Emily Hams, Ryoichi Sugisawa, Dympna J. Connolly, Ciara Doran, Natalia Muñoz‐Wolf, Claudia Gürtler, Katherine A. Fitzgerald, Ed C. Lavelle, Padraic G. Fallon, Andrew Bowie - Immunity 2019 cited by 144
- Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction
Authors: Katherine A. Fitzgerald, Eva M. Pålsson‐McDermott, Andrew Bowie, Caroline A. Jefferies, Ashley Mansell, Gareth Brady, Elizabeth Brint, Aisling Dunne, Pearl Gray, Mary T. Harte, Diane McMurray, Dirk E. Smith, John E. Sims, Timothy A. Bird, Luke O'neill - Nature 2001 cited by 1,259
- The human adaptor SARM negatively regulates adaptor protein TRIF–dependent Toll-like receptor signaling
Authors: Michael Carty, Rory Goodbody, Martina Schröder, Julianne Stack, Paul N Moynagh, Andrew Bowie - Nature Immunology 2006 cited by 539
- Viral targeting of DEAD box protein 3 reveals its role in TBK1/IKKε‐mediated IRF activation
Authors: Martina Schröder, Marcin Baran, Andrew Bowie - The EMBO Journal 2008 cited by 375
- Myeloid cell nuclear differentiation antigen controls the pathogen-stimulated type I interferon cascade in human monocytes by transcriptional regulation of IRF7
Authors: Lili Gu, David Casserly, Gareth Brady, Susan Carpenter, Adrian P. Bracken, Katherine A. Fitzgerald, Leonie Unterholzner, Andrew Bowie - Nature Communications 2022 cited by 53
- Multi-omics characterization of the monkeypox virus infection
Authors: Yiqi Huang, Valter Bergant, Vincent Grass, Quirin Emslander, M. Sabri Hamad, Philipp Hubel, Julia Mergner, Antonio Piras, Karsten Krey, Alexander Henrici, Rupert Öllinger, Yonas M. Tesfamariam, Ilaria Dalla Rosa, Till Bunse, Gerd Sutter, Gregor Ebert, Florian I. Schmidt, Michael Way, Roland Rad, Andrew Bowie, Ulrike Protzer, Andreas Pichlmair - Nature Communications 2024 cited by 60
- Malaria parasite DNA-harbouring vesicles activate cytosolic immune sensors
Authors: Xavier Sisquella, Yifat Ofir‐Birin, Matthew A. Pimentel, Lesley Cheng, Paula Abou Karam, Natália G. Sampaio, Jocelyn Sietsma Penington, Dympna J. Connolly, Tal Giladi, Benjamin J. Scicluna, Robyn A. Sharples, Andreea Waltmann, Dror Avni, Eli Schwartz, Louis Schofield, Ziv Porat, Diana S. Hansen, Anthony T. Papenfuss, Emily M. Eriksson, Motti Gerlic, Andrew F. Hill, Andrew Bowie, Neta Regev‐Rudzki - Nature Communications 2017 cited by 209
- Klebsiella pneumoniae hijacks the Toll-IL-1R protein SARM1 in a type I IFN-dependent manner to antagonize host immunity
Authors: Cláudia Feriotti, Joana Sá‐Pessoa, Ricardo Calderón-González, Lili Gu, Brenda Morris, Ryoichi Sugisawa, José Luis Insua, Michael Carty, Amy Dumigan, Rebecca J. Ingram, Adrien Kissenpfening, Andrew Bowie, José A. Bengoechea - Cell Reports 2022 cited by 42
- CRISPR/Cas9-mediated SARM1 knockout and epitope-tagged mice reveal that SARM1 does not regulate nuclear transcription, but is expressed in macrophages
Authors: Ciara Doran, Ryoichi Sugisawa, Michael Carty, Fiona Roche, Claire Fergus, Karsten Hokamp, Vincent P. Kelly, Andrew Bowie - Journal of Biological Chemistry 2021 cited by 23
- The interleukin-1 receptor-associated kinases: Critical regulators of innate immune signalling
Authors: Sinéad Flannery, Andrew Bowie - Biochemical Pharmacology 2010 cited by 305
- DNA sensors are expressed in astrocytes and microglia in vitro and are upregulated during gliosis in neurodegenerative disease
Authors: Donal J Cox, Robert H. Field, David G. Williams, Marcin Baran, Andrew Bowie, Colm Cunningham, Aisling Dunne - Glia 2015 cited by 79
- Non-canonical inflammasome activation mediates the adjuvanticity of nanoparticles
Authors: Natalia Muñoz‐Wolf, Ross W. Ward, Claire H. Hearnden, Fiona A. Sharp, Joan A. Geoghegan, Katie O’Grady, Craig P. McEntee, Katharine A. Shanahan, Coralie Guy, Andrew Bowie, Matthew Campbell, Carla B. Roces, Giulia Anderluzzi, Cameron Webb, Yvonne Perrie, Emma M. Creagh, Ed C. Lavelle - Cell Reports Medicine 2023 cited by 28
- Recognition of herpesviruses by the innate immune system
Authors: Søren R. Paludan, Andrew Bowie, Kristy Horan, Katherine A. Fitzgerald - Nature reviews. Immunology 2011 cited by 365
- Viral immune modulators perturb the human molecular network by common and unique strategies
Authors: Andreas Pichlmair, Kumaran Kandasamy, Gualtiero Alvisi, Orla Mulhern, Roberto Sacco, Matthias Habjan, Marco Binder, Adrijana Stefanovic, Carol-Ann Eberle, Adriana Gonçalves, Tilmann Bürckstümmer, André C. Müller, Astrid Fauster, Cathleen Holze, Kristina Lindsten, Stephen Goodbourn, Georg Kochs, Friedemann Weber, Ralf Bartenschlager, Andrew Bowie, Keiryn L. Bennett, Jacques Colinge, Giulio Superti‐Furga - Nature 2012 cited by 274
