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Søren R. Paludan

Active 1998–2025

Also published as
Søren R Paludan
132
Papers
19,825
Citations
81
h-index
123
i10-index

Citations

Citations per year for Søren R. Paludan2000: 7 citations2001: 9 citations2002: 11 citations2003: 21 citations2004: 18 citations2005: 48 citations2006: 77 citations2007: 79 citations2008: 111 citations2009: 171 citations2010: 207 citations2011: 221 citations2012: 206 citations2013: 260 citations2014: 210 citations2015: 270 citations2016: 231 citations2017: 262 citations2018: 207 citations2019: 696 citations2020: 893 citations2021: 1,038 citations2022: 940 citations2023: 718 citations2024: 1,087 citations2025: 555 citations2026: 17 citations

Citation sources

Countries

World map of the countries and regions citing this authorUnited States: 2,370 citing papers, 25.3% of this breakdownChina: 1,621 citing papers, 17.3% of this breakdownGermany: 603 citing papers, 6.4% of this breakdownUnited Kingdom: 486 citing papers, 5.2% of this breakdownFrance: 386 citing papers, 4.1% of this breakdownCanada: 286 citing papers, 3.1% of this breakdownDenmark: 278 citing papers, 3% of this breakdownJapan: 257 citing papers, 2.7% of this breakdownItaly: 253 citing papers, 2.7% of this breakdownAustralia: 233 citing papers, 2.5% of this breakdownNetherlands: 214 citing papers, 2.3% of this breakdownIndia: 191 citing papers, 2% of this breakdown
0%25.3%Other 23.4%

Institutions

Fields

  • Immunology and Microbiology41.4%
  • Medicine30.7%
  • Biochemistry, Genetics and Molecular Biology21%
  • Neuroscience2.2%
  • Agricultural and Biological Sciences2.1%
  • Environmental Science0.6%
  • Other2%

Topics

  • interferon and immune responses13.6%
  • Immune Response and Inflammation5.5%
  • Inflammasome and immune disorders4.6%
  • Viral Infections and Vectors3.7%
  • Immune Cell Function and Interaction2.9%
  • Herpesvirus Infections and Treatments2.4%
  • Other67.3%

Coauthors

All papers

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  1. Attenuation of cGAS‐STING signaling is mediated by a p62/SQSTM1‐dependent autophagy pathway activated by TBK1

    Authors: Thaneas Prabakaran, Chiranjeevi Bodda, Christian Krapp, Bao‐cun Zhang, Maria H. Christensen, Chenglong Sun, Line S. Reinert, Yujia Cai, Søren B. Jensen, Morten Kelder Skouboe, Jens Randel Nyengaard, Craig B. Thompson, Robert Jan Lebbink, Ganes C. Sen, Geert Loo, Rikke Nielsen, Masaaki Komatsu, Lene N. Nejsum, Martin R. Jakobsen, Mads Gyrd‐Hansen, Søren R. Paludan - The EMBO Journal 2018 cited by 474

  2. IFI16 is an innate immune sensor for intracellular DNA

    Authors: Leonie Unterholzner, Sinéad E. Keating, Marcin Baran, Kristy Horan, Søren B. Jensen, Shruti Sharma, Cherilyn M. Sirois, Tengchuan Jin, Eicke Latz, Tsan Sam Xiao, Katherine A. Fitzgerald, Søren R. Paludan, Andrew Bowie - Nature Immunology 2010 cited by 1,632

  3. Constitutive immune mechanisms: mediators of host defence and immune regulation

    Authors: Søren R. Paludan, Thomas Pradeu, Seth L. Masters, Trine H. Mogensen - Nature reviews. Immunology 2020 cited by 351

  4. Sensing of HSV-1 by the cGAS–STING pathway in microglia orchestrates antiviral defence in the CNS

    Authors: Line S. Reinert, Katarína Lopušná, Henriette Winther, Chenglong Sun, Martin K. Thomsen, Ramya Nandakumar, Trine H. Mogensen, Morten Meyer, Christian Bjerggaard Vægter, Jens Randel Nyengaard, Katherine A. Fitzgerald, Søren R. Paludan - Nature Communications 2016 cited by 401

  5. SARS-CoV2-mediated suppression of NRF2-signaling reveals potent antiviral and anti-inflammatory activity of 4-octyl-itaconate and dimethyl fumarate

    Authors: David Olagnier, Ensieh Farahani, Jacob Thyrsted, Julia Blay‐Cadanet, Angela Herengt, Manja Idorn, Alon Schneider Hait, Bruno Hernáez, Alice Knudsen, Marie B. Iversen, Mirjam Schilling, Sofie E. Jørgensen, Michelle M. Thomsen, Line S. Reinert, Michael Lappé, Huy‐Dung Hoang, Victoria H. Gilchrist, Anne Louise Hansen, Rasmus N. Ottosen, Camilla G. Nielsen, Charlotte Møller, Demi van der Horst, Suraj Peri, Siddharth Balachandran, Jinrong Huang, Martin R. Jakobsen, Esben B. Svenningsen, Thomas B. Poulsen, Lydia Bartsch, Anne L. Thielke, Yonglun Luo, Tommy Alain, Jan Rehwinkel, Antonio Alcamı́, John Hiscott, Trine H. Mogensen, Søren R. Paludan, Christian K. Holm - Nature Communications 2020 cited by 460

  6. cGAS is activated by DNA in a length‐dependent manner

    Authors: Stefanie Luecke, Andreas Holleufer, Maria H. Christensen, Kasper L. Jønsson, Gerardo A Boni, Lambert K. Sørensen, Mogens Johannsen, Martin R. Jakobsen, Rune Hartmann, Søren R. Paludan - EMBO Reports 2017 cited by 298

  7. Lentiviral delivery of co-packaged Cas9 mRNA and a Vegfa-targeting guide RNA prevents wet age-related macular degeneration in mice

    Authors: Sikai Ling, Shiqi Yang, Xinde Hu, Di Yin, Yao Dai, Xiaoqing Qian, Dawei Wang, Xiaoyong Pan, Jiaxu Hong, Xiaodong Sun, Hui Yang, Søren R. Paludan, Yujia Cai - Nature Biomedical Engineering 2021 cited by 174

  8. STEEP mediates STING ER exit and activation of signaling

    Authors: Bao‐cun Zhang, Ramya Nandakumar, Line S. Reinert, Jinrong Huang, Anders Laustsen, Zongliang Gao, Cheng-long Sun, Søren B. Jensen, Anne Troldborg, Sonia Assil, Martin F. Berthelsen, Carsten Scavenius, Yan Zhang, Samuel J. Windross, David Olagnier, Thaneas Prabakaran, Chiranjeevi Bodda, Ryo Narita, Yujia Cai, Cong-gang Zhang, Harald Stenmark, Christine Doucet, Takeshi Noda, Zheng Guo, Raphaela Goldbach‐Mansky, Rune Hartmann, Zhijian J. Chen, Jan J. Enghild, Rasmus O. Bak, Martin K. Thomsen, Søren R. Paludan - Nature Immunology 2020 cited by 173

  9. STING orchestrates the crosstalk between polyunsaturated fatty acid metabolism and inflammatory responses

    Authors: Isabelle K. Vila, Hanane Chamma, Alizée Steer, Mathilde Saccas, Clara Taffoni, Evgenia Turtoi, Line S. Reinert, Saqib Hussain, Johanna Marines, Lei Jin, Xavier Bonnefont, Mathieu Hubert, Olivier Schwartz, Søren R. Paludan, Gaëtan Van Simaeys, Gilles Doumont, Bijan Sobhian, Dimitriοs Vlachakis, Andrei Turtoï, Nadine Laguette - Cell Metabolism 2022 cited by 185

  10. Targeting herpes simplex virus with CRISPR–Cas9 cures herpetic stromal keratitis in mice

    Authors: Di Yin, Sikai Ling, Dawei Wang, Yao Dai, Hao Jiang, Xujiao Zhou, Søren R. Paludan, Jiaxu Hong, Yujia Cai - Nature Biotechnology 2021 cited by 182

  11. Double-Stranded RNA Is Produced by Positive-Strand RNA Viruses and DNA Viruses but Not in Detectable Amounts by Negative-Strand RNA Viruses

    Authors: Friedemann Weber, Valentina Wagner, Simon Rasmussen, Rune Hartmann, Søren R. Paludan - Journal of Virology 2006 cited by 978

  12. A truncated reverse transcriptase enhances prime editing by split AAV vectors

    Authors: Zongliang Gao, Sujan Ravendran, Nanna S. Mikkelsen, Jakob Haldrup, Huiqiang Cai, Xiangning Ding, Søren R. Paludan, Martin K. Thomsen, Jacob Giehm Mikkelsen, Rasmus O. Bak - Molecular Therapy 2022 cited by 96

  13. DNA-stimulated cell death: implications for host defence, inflammatory diseases and cancer

    Authors: Søren R. Paludan, Line S. Reinert, Veit Hornung - Nature reviews. Immunology 2019 cited by 194

  14. The cGAS-STING pathway is a therapeutic target in a preclinical model of hepatocellular carcinoma

    Authors: Martin K. Thomsen, Morten Kelder Skouboe, Cédric Boularan, Fabienne Vernejoul, Thierry Lioux, Siv L. Leknes, Martin F. Berthelsen, Maria Riedel, Huiqiang Cai, Justin V. Joseph, Éric Pérouzel, Michèle Tiraby, Mikkel Holm Vendelbo, Søren R. Paludan - Oncogene 2019 cited by 94

  15. Microglia and amyloid plaque formation in Alzheimer's disease – Evidence, possible mechanisms, and future challenges

    Authors: Stefanie Fruhwürth, Henrik Zetterberg, Søren R. Paludan - Journal of Neuroimmunology 2024 cited by 68

  16. Immune Sensing of DNA

    Authors: Søren R. Paludan, Andrew Bowie - Immunity 2013 cited by 745

  17. Brain immune cells undergo cGAS/STING-dependent apoptosis during herpes simplex virus type 1 infection to limit type I IFN production

    Authors: Line S. Reinert, Ahmad Rashidi, Diana Tran, Georgios Katzilieris‐Petras, Astrid Korning Hvidt, Mette Gohr, Stefanie Fruhwürth, Chiranjeevi Bodda, Martin K. Thomsen, Mikkel Holm Vendelbo, Ahmad Raza Khan, Brian Hansen, Petra Bergström, Lotta Agholme, Trine H. Mogensen, Maria H. Christensen, Jens Randel Nyengaard, Ganes C. Sen, Henrik Zetterberg, Georges M. G. M. Verjans, Søren R. Paludan - Journal of Clinical Investigation 2020 cited by 113

  18. Influenza A virus targets a cGAS-independent STING pathway that controls enveloped RNA viruses

    Authors: Christian K. Holm, Stine H. Rahbek, Hans Henrik Gad, Rasmus O. Bak, Martin R. Jakobsen, Zhaozaho Jiang, Anne Louise Hansen, Simon Kok Jensen, Chenglong Sun, Martin K. Thomsen, Anders Laustsen, Camilla G. Nielsen, Kasper Severinsen, Yingluo Xiong, Dara Burdette, Veit Hornung, Robert Jan Lebbink, Mogens Duch, Katherine A. Fitzgerald, Shervin Bahrami, Jacob Giehm Mikkelsen, Rune Hartmann, Søren R. Paludan - Nature Communications 2016 cited by 228

  19. Human ZBP1 induces cell death‐independent inflammatory signaling via RIPK3 and RIPK1

    Authors: Ruoshi Peng, Chris Kedong Wang, Xuan Wang‐Kan, Manja Idorn, Majken Kjær, Felix Zhou, Berthe Katrine Fiil, Frederik Timmermann, Susana Orozco, Julia McCarthy, Carol S. Leung, Xin Lü, Katrin Bagola, Jan Rehwinkel, Andrew Oberst, Jonathan Maelfait, Søren R. Paludan, Mads Gyrd‐Hansen - EMBO Reports 2022 cited by 85

  20. A STING antagonist modulating the interaction with STIM1 blocks ER-to-Golgi trafficking and inhibits lupus pathology

    Authors: Thaneas Prabakaran, Anne Troldborg, Sarinya Kumpunya, Isara Alee, Emilija Marinković, Samuel J. Windross, Ramya Nandakumar, Ryo Narita, Bao‐cun Zhang, Mikkel Carstensen, Pichpisith Pierre Vejvisithsakul, Mikkel H. S. Marqvorsen, Marie B. Iversen, Christian K. Holm, Lars Østergaard, Finn Skou Pedersen, Trairak Pisitkun, Rayk Behrendt, Prapaporn Pisitkun, Søren R. Paludan - EBioMedicine 2021 cited by 88

  21. TLR2 and TLR7 mediate distinct immunopathological and antiviral plasmacytoid dendritic cell responses to SARS‐CoV‐2 infection

    Authors: Renée M. van der Sluis, Lamin B. Cham, Albert Gris‐Oliver, Kristine Raaby Gammelgaard, Jesper G Pedersen, Manja Idorn, Ulvi Ahmadov, Sabina Sánchez-Hernández, Ena Cémalovic, Stine H. Godsk, Jacob Thyrsted, Jesper Damsgaard Gunst, Silke D Nielsen, Janni J. Jørgensen, Tobias Wang Bjerg, Anders Laustsen, Line S. Reinert, David Olagnier, Rasmus O. Bak, Mads Kjølby, Christian K. Holm, Martin Tolstrup, Søren R. Paludan, Lasse S. Kristensen, Ole S. Søgaard, Martin R Jakobsen - The EMBO Journal 2022 cited by 101

  22. IFI16 is required for DNA sensing in human macrophages by promoting production and function of cGAMP

    Authors: Kasper L. Jønsson, Anders Laustsen, Christian Krapp, Kristian Alsbjerg Skipper, Karthiga Thavachelvam, Dominik Hotter, Johanne H. Egedal, Mads Kjølby, Pejman Mohammadi, Thaneas Prabakaran, Lambert K. Sørensen, Cheng-long Sun, Søren B. Jensen, Christian K. Holm, Robert Jan Lebbink, Mogens Johannsen, M. Nyegaard, Jacob Giehm Mikkelsen, Frank Kirchhoff, Søren R. Paludan, Maria Jakobsen - Nature Communications 2017 cited by 287

  23. Functional IRF3 deficiency in a patient with herpes simplex encephalitis

    Authors: Line Lykke Andersen, Nanna Mørk, Line S. Reinert, Emil Kofod‐Olsen, Ryo Narita, Sofie E. Jørgensen, Kristian Alsbjerg Skipper, Klara Höning, Hans Henrik Gad, Lars Østergaard, Torben F. Ørntoft, Veit Hornung, Søren R. Paludan, Jacob Giehm Mikkelsen, Takashi Fujita, Mette Christiansen, Rune Hartmann, Trine H. Mogensen - The Journal of Experimental Medicine 2015 cited by 225

  24. Life-threatening viral disease in a novel form of autosomal recessive IFNAR2 deficiency in the Arctic

    Authors: C.J. Duncan, Morten Kelder Skouboe, Sophie Howarth, Anne Kruse Hollensen, Rui Chen, Malene Landbo Børresen, Benjamin Thompson, Jarmila Stremenova Spegarova, Catherine F. Hatton, Frederik Filip Stæger, Mette K. Andersen, John Whittaker, Søren R. Paludan, Sofie E. Jørgensen, Martin K. Thomsen, Jacob Giehm Mikkelsen, Carsten Heilmann, Daniela Buhaş, Nina Friesgaard Øbro, Jakob Thaning Bay, Hanne Vibeke Marquart, M. Teresa de la Morena, Joseph Klejka, Matthew Hirschfeld, Line Borgwardt, Isabel Forss, Tania Nicole Masmas, Anja Poulsen, Francisco Noya, Guy A. Rouleau, Torben Hansen, Sirui Zhou, Anders Albrechtsen, Reza Alizadehfar, Eric J. Allenspach, Sophie Hambleton, Trine H. Mogensen - The Journal of Experimental Medicine 2022 cited by 92