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Zhijian J. Chen

Active 1996–2026

151
Papers
76,139
Citations
111
h-index
150
i10-index

Citations

Citations per year for Zhijian J. Chen1970: 1 citations1976: 1 citations1991: 2 citations1992: 2 citations1993: 1 citations1996: 13 citations1997: 80 citations1998: 121 citations1999: 145 citations2000: 135 citations2001: 163 citations2002: 196 citations2003: 198 citations2004: 200 citations2005: 290 citations2006: 460 citations2007: 464 citations2008: 495 citations2009: 678 citations2010: 682 citations2011: 764 citations2012: 812 citations2013: 899 citations2014: 967 citations2015: 1,020 citations2016: 1,007 citations2017: 1,248 citations2018: 1,238 citations2019: 3,083 citations2020: 4,046 citations2021: 4,092 citations2022: 3,742 citations2023: 3,301 citations2024: 4,421 citations2025: 2,499 citations2026: 81 citations1971–1975: no citations, so these years are not shown1977–1990: no citations, so these years are not shown1994–1995: no citations, so these years are not shown

Citation sources

Countries

World map of the countries and regions citing this authorUnited States: 8,054 citing papers, 29.5% of this breakdownChina: 6,041 citing papers, 22.1% of this breakdownGermany: 1,511 citing papers, 5.5% of this breakdownUnited Kingdom: 1,394 citing papers, 5.1% of this breakdownJapan: 1,033 citing papers, 3.8% of this breakdownFrance: 975 citing papers, 3.6% of this breakdownCanada: 852 citing papers, 3.1% of this breakdownAustralia: 560 citing papers, 2.1% of this breakdownItaly: 559 citing papers, 2% of this breakdownSouth Korea: 462 citing papers, 1.7% of this breakdownSwitzerland: 460 citing papers, 1.7% of this breakdownIndia: 407 citing papers, 1.5% of this breakdown
0%29.5%Other 18.3%

Institutions

Fields

  • Biochemistry, Genetics and Molecular Biology36.6%
  • Immunology and Microbiology36.1%
  • Medicine20.6%
  • Neuroscience1.9%
  • Agricultural and Biological Sciences1.8%
  • Engineering1.3%
  • Other1.7%

Topics

  • interferon and immune responses12.4%
  • Immune Response and Inflammation5.2%
  • Inflammasome and immune disorders4.4%
  • NF-κB Signaling Pathways3.4%
  • Ubiquitin and proteasome pathways3.2%
  • Viral Infections and Vectors2.6%
  • Other68.8%

Coauthors

All papers

Open in search
  1. Cyclic GMP-AMP Synthase Is a Cytosolic DNA Sensor That Activates the Type I Interferon Pathway

    Authors: Lijun Sun, Jiaxi Wu, Fenghe Du, Xiang Chen, Zhijian J. Chen - Science 2012 cited by 4,944

  2. Regulation and function of the cGAS–STING pathway of cytosolic DNA sensing

    Authors: Qi Chen, Lijun Sun, Zhijian J. Chen - Nature Immunology 2016 cited by 2,245

  3. Cyclic GMP-AMP Is an Endogenous Second Messenger in Innate Immune Signaling by Cytosolic DNA

    Authors: Jiaxi Wu, Lijun Sun, Xiang Chen, Fenghe Du, Heping Shi, Chuo Chen, Zhijian J. Chen - Science 2012 cited by 2,541

  4. Phosphorylation of innate immune adaptor proteins MAVS, STING, and TRIF induces IRF3 activation

    Authors: Siqi Liu, Xin Cai, Jiaxi Wu, Qian Cong, Xiang Chen, Tuo Li, Fenghe Du, Junyao Ren, Youtong Wu, Nick V. Grishin, Zhijian J. Chen - Science 2015 cited by 1,945

  5. Autophagy induction via STING trafficking is a primordial function of the cGAS pathway

    Authors: Xiang Gui, Hui Yang, Tuo Li, Xiaojun Tan, Peiqing Shi, Minghao Li, Fenghe Du, Zhijian J. Chen - Nature 2019 cited by 1,289

  6. STING-Dependent Cytosolic DNA Sensing Promotes Radiation-Induced Type I Interferon-Dependent Antitumor Immunity in Immunogenic Tumors

    Authors: Liufu Deng, Hua Liang, Meng Xu, Xuanming Yang, Byron Burnette, Ainhoa Arina, Xiao-Dong Li, Helena J. Mauceri, Michael A. Beckett, Thomas E. Darga, Xiaona Huang, Thomas F. Gajewski, Zhijian J. Chen, Yang‐Xin Fu, Ralph R. Weichselbaum - Immunity 2014 cited by 2,079

  7. Structural basis of STING binding with and phosphorylation by TBK1

    Authors: Conggang Zhang, Guijun Shang, Xiang Gui, Xuewu Zhang, Xiao‐chen Bai, Zhijian J. Chen - Nature 2019 cited by 1,090

  8. cGAS in action: Expanding roles in immunity and inflammation

    Authors: Andrea Ablasser, Zhijian J. Chen - Science 2019 cited by 1,070

  9. Structures and Mechanisms in the cGAS-STING Innate Immunity Pathway

    Authors: Xuewu Zhang, Xiao‐chen Bai, Zhijian J. Chen - Immunity 2020 cited by 806

  10. DNA-induced liquid phase condensation of cGAS activates innate immune signaling

    Authors: Mingjian Du, Zhijian J. Chen - Science 2018 cited by 1,074

  11. Cryo-EM structures of STING reveal its mechanism of activation by cyclic GMP–AMP

    Authors: Guijun Shang, Conggang Zhang, Zhijian J. Chen, Xiao‐chen Bai, Xuewu Zhang - Nature 2019 cited by 766

  12. The cGAS–cGAMP–STING pathway connects DNA damage to inflammation, senescence, and cancer

    Authors: Tuo Li, Zhijian J. Chen - The Journal of Experimental Medicine 2018 cited by 1,256

  13. TBK1 recruitment to STING activates both IRF3 and NF-κB that mediate immune defense against tumors and viral infections

    Authors: Seoyun Yum, Minghao Li, Yan Fang, Zhijian J. Chen - National Academy of Sciences, Proceedings of the National Academy of Sciences 2021 cited by 538

  14. Identification and Characterization of MAVS, a Mitochondrial Antiviral Signaling Protein that Activates NF-κB and IRF3

    Authors: Rashu B. Seth, Lijun Sun, Chee-Kwee Ea, Zhijian J. Chen - Cell 2005 cited by 3,318

  15. STING Specifies IRF3 Phosphorylation by TBK1 in the Cytosolic DNA Signaling Pathway

    Authors: Yasuo Tanaka, Zhijian J. Chen - Science Signaling 2012 cited by 1,298

  16. cGAS is essential for cellular senescence

    Authors: Hui Yang, Hanze Wang, Junyao Ren, Qi Chen, Zhijian J. Chen - National Academy of Sciences, Proceedings of the National Academy of Sciences 2017 cited by 981

  17. A STING-activating nanovaccine for cancer immunotherapy

    Authors: Min Luo, Hua Wang, Zhaohui Wang, Haocheng Cai, Zhigang Lu, Yang Li, Mingjian Du, Gang Huang, Chensu Wang, Xiang Chen, Matthew R. Porembka, Jayanthi Lea, Arthur E. Frankel, Yang-Xin Fu, Zhijian J. Chen, Jinming Gao - Nature Nanotechnology 2017 cited by 889

  18. PtdIns4P on dispersed trans-Golgi network mediates NLRP3 inflammasome activation

    Authors: Jueqi Chen, Zhijian J. Chen - Nature 2018 cited by 692

  19. Cyclic GMP-AMP Containing Mixed Phosphodiester Linkages Is An Endogenous High-Affinity Ligand for STING

    Authors: Xu Zhang, Heping Shi, Jiaxi Wu, Xuewu Zhang, Lijun Sun, Chuo Chen, Zhijian J. Chen - Molecular Cell 2013 cited by 1,061

  20. Apoptotic Caspases Prevent the Induction of Type I Interferons by Mitochondrial DNA

    Authors: Anthony Rongvaux, Ruaidhrí Jackson, Christian C. D. Harman, Tuo Li, A. Phillip West, Marcel R. de Zoete, Youtong Wu, Brian Yordy, Saquib A. Lakhani, Chia-Yi Kuan, Tadatsugu Taniguchi, Gerald S. Shadel, Zhijian J. Chen, Akiko Iwasaki, Richard A. Flavell - Cell 2014 cited by 835

  21. Tumor-targeted delivery of a STING agonist improves cancer immunotherapy

    Authors: Youtong Wu, Yan Fang, Wei Qi, Heping Shi, Huiling Tan, Yafang Deng, Zhiqun Zeng, Jian Qiu, Chuo Chen, Lijun Sun, Zhijian J. Chen - National Academy of Sciences, Proceedings of the National Academy of Sciences 2022 cited by 195

  22. Pivotal Roles of cGAS-cGAMP Signaling in Antiviral Defense and Immune Adjuvant Effects

    Authors: Xiao-Dong Li, Jiaxi Wu, Daxing Gao, Hua Wang, Lijun Sun, Zhijian J. Chen - Science 2013 cited by 1,119

  23. The cGAS-cGAMP-STING Pathway of Cytosolic DNA Sensing and Signaling

    Authors: Xin Cai, Yu‐Hsin Chiu, Zhijian J. Chen - Molecular Cell 2014 cited by 968

  24. MAVS Forms Functional Prion-like Aggregates to Activate and Propagate Antiviral Innate Immune Response

    Authors: Fajian Hou, Lijun Sun, Hui Zheng, Brian Skaug, Qiu‐Xing Jiang, Zhijian J. Chen - Cell 2011 cited by 1,283