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Seth L. Masters

Active 2005–2025

90
Papers
27,881
Citations
68
h-index
88
i10-index

Citations

Citations per year for Seth L. Masters1964: 1 citations1988: 1 citations1991: 2 citations1996: 1 citations2000: 2 citations2003: 1 citations2006: 6 citations2007: 20 citations2008: 66 citations2009: 87 citations2010: 108 citations2011: 152 citations2012: 153 citations2013: 195 citations2014: 223 citations2015: 333 citations2016: 428 citations2017: 526 citations2018: 584 citations2019: 1,436 citations2020: 1,756 citations2021: 1,847 citations2022: 1,670 citations2023: 1,347 citations2024: 1,893 citations2025: 1,062 citations2026: 16 citations1965–1987: no citations, so these years are not shown1989–1990: no citations, so these years are not shown1992–1995: no citations, so these years are not shown1997–1999: no citations, so these years are not shown2001–2002: no citations, so these years are not shown2004–2005: no citations, so these years are not shown

Citation sources

Countries

World map of the countries and regions citing this authorUnited States: 3,955 citing papers, 22.3% of this breakdownChina: 3,683 citing papers, 20.8% of this breakdownGermany: 1,076 citing papers, 6.1% of this breakdownUnited Kingdom: 935 citing papers, 5.3% of this breakdownAustralia: 694 citing papers, 3.9% of this breakdownFrance: 576 citing papers, 3.3% of this breakdownItaly: 573 citing papers, 3.2% of this breakdownCanada: 487 citing papers, 2.7% of this breakdownJapan: 406 citing papers, 2.3% of this breakdownSpain: 396 citing papers, 2.2% of this breakdownNetherlands: 396 citing papers, 2.2% of this breakdownSwitzerland: 347 citing papers, 2% of this breakdown
0%22.3%Other 23.7%

Institutions

Fields

  • Biochemistry, Genetics and Molecular Biology43%
  • Medicine28.4%
  • Immunology and Microbiology22.2%
  • Neuroscience3.3%
  • Nursing0.7%
  • Agricultural and Biological Sciences0.7%
  • Other1.7%

Topics

  • Inflammasome and immune disorders11.6%
  • interferon and immune responses4.2%
  • Immune cells in cancer3.7%
  • Immune Response and Inflammation2.8%
  • Immune Cell Function and Interaction2.7%
  • IL-33, ST2, and ILC Pathways2%
  • Other73%

Coauthors

All papers

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  1. Succinate is an inflammatory signal that induces IL-1β through HIF-1α

    Authors: Gillian M. Tannahill, Annie M. Curtis, Juraj Adamik, Eva M. Pålsson‐McDermott, Anne F. McGettrick, Gautam Goel, Christian Frezza, Nicholas J. Bernard, Beth Kelly, Niamh H. Foley, Liang Zheng, Agnès Gardet, Zhen Tong, S. S. Jany, Sinéad C. Corr, Moritz Haneklaus, Brian E. Caffrey, Kerry A. Pierce, Sarah R. Walmsley, Federico C. Beasley, Eoin P. Cummins, Victor Nizet, Moira K. B. Whyte, Cormac T. Taylor, Hening Lin, Seth L. Masters, Eyal Gottlieb, Vincent P. Kelly, Clary B. Clish, Philip E. Auron, Ramnik J. Xavier, Luke O'neill - Nature 2013 cited by 4,111

  2. A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases

    Authors: Rebecca C. Coll, Avril A. B. Robertson, Jae Jin Chae, Sarah Higgins, Raúl Muñoz-Planillo, Marco Inserra, Irina Vetter, Lara S. Dungan, Brian G. Monks, Andrea Stutz, Daniel E. Croker, Mark S. Butler, Moritz Haneklaus, Caroline E. Sutton, Gabriel Núñez, Eicke Latz, Daniel L. Kastner, Kingston H. G. Mills, Seth L. Masters, Kate Schroder, Matthew A. Cooper, Luke O'neill - Nature Medicine 2015 cited by 2,784

  3. TDP-43 Triggers Mitochondrial DNA Release via mPTP to Activate cGAS/STING in ALS

    Authors: Chien‐Hsiung Yu, Sophia Davidson, Cassandra R. Harapas, James B. Hilton, Michael J. Mlodzianoski, Pawat Laohamonthonkul, Cynthia Louis, Ronnie Ren Jie Low, Jonas Moecking, Dominic De Nardo, Katherine R. Balka, Dale J. Calleja, Fiona Moghaddas, Erya Ni, Catriona McLean, André L. Samson, Shiraz Tyebji, Christopher J. Tonkin, Christopher R. Bye, Bradley J. Turner, Geneviève Pépin, Michael P. Gantier, Kelly L. Rogers, Kate McArthur, Peter J. Crouch, Seth L. Masters - Cell 2020 cited by 1,038

  4. NLRP3 inflammasome blockade reduces liver inflammation and fibrosis in experimental NASH in mice

    Authors: Auvro R. Mridha, Alexander Wree, Avril A. B. Robertson, Matthew M. Yeh, Casey D. Johnson, Derrick M. Van Rooyen, Fahrettin Haczeyni, Narci Teoh, Christopher Savard, George N. Ioannou, Seth L. Masters, Kate Schroder, Matthew A. Cooper, Ariel E. Feldstein, Geoffrey C. Farrell - Journal of Hepatology 2017 cited by 1,070

  5. TBK1 and IKKε Act Redundantly to Mediate STING-Induced NF-κB Responses in Myeloid Cells

    Authors: Katherine R. Balka, Cynthia Louis, Tahnee L. Saunders, Amber M. Smith, Dale J. Calleja, Damian B. D’Silva, Fiona Moghaddas, Maximilien Tailler, Kate E. Lawlor, Yifan Zhan, Christopher J. Burns, Ian P. Wicks, Jonathan J. Miner, Benjamin T. Kile, Seth L. Masters, Dominic De Nardo - Cell Reports 2020 cited by 463

  6. Constitutive immune mechanisms: mediators of host defence and immune regulation

    Authors: Søren R. Paludan, Thomas Pradeu, Seth L. Masters, Trine H. Mogensen - Nature reviews. Immunology 2020 cited by 351

  7. Active MLKL triggers the NLRP3 inflammasome in a cell-intrinsic manner

    Authors: Stephanie A. Conos, Kaiwen Chen, Dominic De Nardo, Hideki Hara, Lachlan Whitehead, Gabriel Núñez, Seth L. Masters, James M. Murphy, Kate Schroder, David L. Vaux, Kate E. Lawlor, Lisa Lindqvist, James E. Vince - National Academy of Sciences, Proceedings of the National Academy of Sciences 2017 cited by 478

  8. Evidence that TLR4 Is Not a Receptor for Saturated Fatty Acids but Mediates Lipid-Induced Inflammation by Reprogramming Macrophage Metabolism

    Authors: Graeme I. Lancaster, Katherine G. Langley, Nils Berglund, Hélène L. Kammoun, Saskia Reibe, Emma Estévez, Jacquelyn M. Weir, Natalie A. Mellett, Gerard Pernes, James R. W. Conway, Man K.S. Lee, Paul Timpson, Andrew Murphy, Seth L. Masters, Steve Gerondakis, Nenad Bartoniček, Dominik C. Kaczorowski, Marcel E. Dinger, Peter J. Meikle, Peter J. Bond, Mark A. Febbraio - Cell Metabolism 2018 cited by 447

  9. RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL

    Authors: Kate E. Lawlor, Nufail Khan, Alison Mildenhall, Motti Gerlic, Ben A. Croker, Akshay A. D’Cruz, Cathrine Hall, Sukhdeep K. Spall, Holly Anderton, Seth L. Masters, Maryam Rashidi, Ian P. Wicks, Warren S. Alexander, Yasuhiro Mitsuuchi, Christopher A. Benetatos, Stephen M. Condon, W. Wei‐Lynn Wong, John Silke, David L. Vaux, James E. Vince - Nature Communications 2015 cited by 641

  10. Homeostasis-altering molecular processes as mechanisms of inflammasome activation

    Authors: Adrian Liston, Seth L. Masters - Nature reviews. Immunology 2017 cited by 450

  11. Mutations that prevent caspase cleavage of RIPK1 cause autoinflammatory disease

    Authors: Najoua Lalaoui, Steven E. Boyden, Hirotsugu Oda, Geryl Wood, Deborah L. Stone, Diep Chau, Lin Liu, Monique Stoffels, Tobias Kratina, Kate E. Lawlor, Kristien J.M. Zaal, Patrycja Hoffmann, Nima Etemadi, Kristy Shield‐Artin, Christine Biben, Wanxia Li Tsai, Mary Blake, Hye Sun Kuehn, Dan Yang, Holly Anderton, Natasha Silke, Laurens Wachsmuth, Lixin Zheng, Natalia Sampaio Moura, David B. Beck, Gustavo Gutierrez-Cruz, Amanda K. Ombrello, Gineth Paola Pinto-Patarroyo, Andrew J. Kueh, Marco J. Herold, Cathrine Hall, Hongying Wang, Jae Jin Chae, Natalia I. Dmitrieva, Mark McKenzie, Amanda Light, Beverly Barham, Anne Jones, Tina Romeo, Qing Zhou, Ivona Aksentijevich, James C. Mullikin, Andrew J. Gross, Anthony K. Shum, Edwin D. Hawkins, Seth L. Masters, Michael J. Lenardo, Manfred Boehm, Sergio D. Rosenzweig, Manolis Pasparakis, Anne K. Voss, Massimo Gadina, Daniel L. Kastner, John Silke - Nature 2019 cited by 333

  12. Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes

    Authors: Seth L. Masters, Aisling Dunne, Shoba Subramanian, Rebecca L. Hull, Gillian M. Tannahill, Fiona A. Sharp, Christine Becker, Luigi Franchi, Eiji Yoshihara, Zhe Chen, N Mullooly, Lisa A. Mielke, James Harris, Rebecca C. Coll, Kingston H. G. Mills, K. Hun Mok, Philip Newsholme, Gabriel Nuñez, Junji Yodoi, Steven E. Kahn, Ed C. Lavelle, Luke O'neill - Nature Immunology 2010 cited by 1,315

  13. Organellar homeostasis and innate immune sensing

    Authors: Cassandra R. Harapas, Elina Idiiatullina, Mahmoud Al‐Azab, Katja Hrovat-Schaale, Thomas Reygaerts, Annemarie Steiner, Pawat Laohamonthonkul, Sophia Davidson, Chien‐Hsiung Yu, Lee M. Booty, Seth L. Masters - Nature reviews. Immunology 2022 cited by 155

  14. ZAKα-driven ribotoxic stress response activates the human NLRP1 inflammasome

    Authors: Kim S. Robinson, Gee Ann Toh, Pritisha Rozario, Rae Chua, Stefan Bauernfried, Zijin Sun, Muhammad Jasrie Firdaus, Shima Bayat, Rhea Nadkarni, Zhi Sheng Poh, Khek‐Chian Tham, Cassandra R. Harapas, Chrissie Lim, Werncui Chu, Celest W. S. Tay, Kiat Yi Tan, Tianyun Zhao, Carine Bonnard, Radoslaw M. Sobota, John E. Connolly, John Common, Seth L. Masters, Kaiwen Chen, Lena Ho, Bin Wu, Veit Hornung, Franklin L. Zhong - Science 2022 cited by 167

  15. NLRP3 inflammasome activation downstream of cytoplasmic LPS recognition by both caspase‐4 and caspase‐5

    Authors: Paul J. Baker, Dave Boucher, Damiën Bierschenk, Christina Tebartz, Paul G. Whitney, Damian B. D’Silva, Maria C. Tanzer, Mercedes Monteleone, Avril A. B. Robertson, Matthew A. Cooper, Silvia Álvarez-Díaz, Marco J. Herold, Sammy Bedoui, Kate Schroder, Seth L. Masters - European Journal of Immunology 2015 cited by 356

  16. Germline NLRP1 Mutations Cause Skin Inflammatory and Cancer Susceptibility Syndromes via Inflammasome Activation

    Authors: Franklin L. Zhong, Ons Mamaï, Lorenzo Sborgi, L. Boussofara, Richard A. Hopkins, Kim S. Robinson, Ildikó Szeverényi, Takuya Takeichi, Reshmaa Balaji, Aristotle Lau, Hazel Tye, Keya Roy, Carine Bonnard, Patricia J. Ahl, Leigh Ann Jones, Paul J. Baker, Lukáš Lacina, Atsushi Otsuka, Pierre Fournié, François Malecaze, E. Birgitte Lane, Masashi Akiyama, Kenji Kabashima, John E. Connolly, Seth L. Masters, Vincent Soler, Salma Samir Omar, John A. McGrath, Roxana Nedelcu, Moez Gribaa, M. Denguezli, Ali Saâd, Sebastian Hiller, Bruno Reversade - Cell 2016 cited by 438

  17. The transcriptional regulators IRF4, BATF and IL-33 orchestrate development and maintenance of adipose tissue–resident regulatory T cells

    Authors: Ajithkumar Vasanthakumar, Kazuyo Moro, Annie Xin, Yang Liao, Renee Gloury, Shimpei Kawamoto, Sidonia Fagarasan, Lisa A. Mielke, Shoukat Afshar‐Sterle, Seth L. Masters, Susumu Nakae, Hirohisa Saito, John M. Wentworth, Peng Li, Wei Liao, Warren J. Leonard, Gordon K. Smyth, Wei Shi, Stephen L. Nutt, Shigeo Koyasu, Axel Kallies - Nature Immunology 2015 cited by 544

  18. Adipose Tissue Macrophages Promote Myelopoiesis and Monocytosis in Obesity

    Authors: Prabhakara R. Nagareddy, Michael J. Kraakman, Seth L. Masters, Roslynn A. Stirzaker, Darren J. Gorman, Ryan W. Grant, Dragana Dragoljevic, Eun Shil Hong, Ahmed Abdel‐Latif, Susan S. Smyth, Sung Hee Choi, Judith Körner, Karin Bornfeldt, Edward A. Fisher, Vishwa Deep Dixit, Alan R. Tall, Ira J. Goldberg, Andrew Murphy - Cell Metabolism 2014 cited by 497

  19. RIPK1 Regulates RIPK3-MLKL-Driven Systemic Inflammation and Emergency Hematopoiesis

    Authors: James A. Rickard, Joanne A. O’Donnell, Joseph M. Evans, Najoua Lalaoui, Ashleigh R. Poh, TeWhiti Rogers, James E. Vince, Kate E. Lawlor, Robert L. Ninnis, Holly Anderton, Cathrine Hall, Sukhdeep K. Spall, Toby J. Phesse, Helen E. Abud, Louise H. Cengia, Jason Corbin, Sandra Mifsud, Ladina Di Rago, Donald Metcalf, Matthias Ernst, Grant Dewson, Andrew W. Roberts, Warren S. Alexander, James M. Murphy, Paul G. Ekert, Seth L. Masters, David L. Vaux, Ben A. Croker, Motti Gerlic, John Silke - Cell 2014 cited by 598

  20. Interleukin-1 receptor–associated kinase 4 (IRAK4) plays a dual role in myddosome formation and Toll-like receptor signaling

    Authors: Dominic De Nardo, Katherine R. Balka, Yamel Cardona Gloria, Vikram R. Rao, Eicke Latz, Seth L. Masters - Journal of Biological Chemistry 2018 cited by 146

  21. Myeloid-derived miR-223 regulates intestinal inflammation via repression of the NLRP3 inflammasome

    Authors: Viola Neudecker, Moritz Haneklaus, Owen Jensen, Ludmila Khailová, Joanne C. Masterson, Hazel Tye, Kathryn A. Biette, Paul Jedlicka, Kelley S. Brodsky, Mark E. Gerich, Matthias Mack, Avril A. B. Robertson, Matthew A. Cooper, Glenn T. Furuta, Charles A. Dinarello, Luke O'neill, Holger K. Eltzschig, Seth L. Masters, Eóin N. McNamee - The Journal of Experimental Medicine 2017 cited by 359

  22. The Mitochondrial Apoptotic Effectors BAX/BAK Activate Caspase-3 and -7 to Trigger NLRP3 Inflammasome and Caspase-8 Driven IL-1β Activation

    Authors: James E. Vince, Dominic De Nardo, Wenqing Gao, Angelina J. Vince, Cathrine Hall, Kate McArthur, Daniel S. Simpson, Swarna Lekha Vijayaraj, Lisa Lindqvist, Philippe Bouillet, Mark A. Rizzacasa, Si Ming Man, John Silke, Seth L. Masters, Guillaume Lessène, David C.S. Huang, Daniel H.D. Gray, Benjamin T. Kile, Feng Shao, Kate E. Lawlor - Cell Reports 2018 cited by 237

  23. Deficiency in coatomer complex I causes aberrant activation of STING signalling

    Authors: Annemarie Steiner, Katja Hrovat-Schaale, Ignazia Prigione, Chien‐Hsiung Yu, Pawat Laohamonthonkul, Cassandra R. Harapas, Ronnie Ren Jie Low, Dominic De Nardo, Laura F. Dagley, Michael J. Mlodzianoski, Kelly L. Rogers, Thomas Zillinger, Gunther Hartmann, Michael P. Gantier, Marco Gattorno, Matthias Geyer, Stefano Volpi, Sophia Davidson, Seth L. Masters - Nature Communications 2022 cited by 96

  24. Human DPP9 represses NLRP1 inflammasome and protects against autoinflammatory diseases via both peptidase activity and FIIND domain binding

    Authors: Franklin L. Zhong, Kim S. Robinson, Daniel Eng Thiam Teo, Kiat Yi Tan, Chrissie Lim, Cassandra R. Harapas, Chien‐Hsiung Yu, William Xie, Radoslaw M. Sobota, Bijin Au, Richard A. Hopkins, Andrea D’Osualdo, John C. Reed, John E. Connolly, Seth L. Masters, Bruno Reversade - Journal of Biological Chemistry 2018 cited by 250