Philippe Bouillet
Active 1995–2025
- 74
- Papers
- 18,565
- Citations
- 72
- h-index
- 74
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Biochemistry, Genetics and Molecular Biology53.6%
- Medicine27.7%
- Immunology and Microbiology13.4%
- Neuroscience2.6%
- Agricultural and Biological Sciences0.5%
- Pharmacology, Toxicology and Pharmaceutics0.5%
- Other1.7%
Topics
- Cell death mechanisms and regulation9%
- Immune Cell Function and Interaction3.8%
- Autophagy in Disease and Therapy3.5%
- Endoplasmic Reticulum Stress and Disease3.1%
- T-cell and B-cell Immunology3%
- Cancer-related Molecular Pathways2.6%
- Other75%
Coauthors
- Andreas Strasser47
- David C.S. Huang16
- Jerry M. Adams11
- Pierre Chambon11
- Pascal Dollé10
- Lorraine A. O’Reilly9
- Suzanne Cory8
- Hamsa Puthalakath7
- Marco J. Herold7
- Mustapha Oulad‐Abdelghani7
- W. Douglas Fairlie7
- David M. Tarlinton6
- Erinna F. Lee6
- John Silke6
- Claire Chazaud5
- Clare L. Scott5
- Daniel H.D. Gray5
- Stefan Glaser5
- Andrew W. Roberts4
- Cassandra J. Vandenberg4
- Donald Metcalf4
- Gabrielle T. Belz4
- Marc Pellegrini4
- Thomas Kaufmann4
All papers
- ER Stress Triggers Apoptosis by Activating BH3-Only Protein Bim
Authors: Hamsa Puthalakath, Lorraine A. O’Reilly, Priscilla Gunn, Lily Lee, Priscilla N. Kelly, Nicholas D. Huntington, Peter Hughes, Ewa M. Michalak, Jennifer L. McKimm‐Breschkin, Noburo Motoyama, Tomomi Gotoh, Shizuo Akira, Philippe Bouillet, Andreas Strasser - Cell 2007 cited by 1,427
- VDAC2 enables BAX to mediate apoptosis and limit tumor development
Authors: Hui San Chin, Xiang Li, Iris K. L. Tan, Robert L. Ninnis, Boris Reljić, Kristen Scicluna, Laura F. Dagley, Jarrod J. Sandow, Gemma L. Kelly, André L. Samson, Stéphane Chappaz, Seong Lin Khaw, Catherine Chang, Andrew Morokoff, Kerstin Brinkmann, Andrew I. Webb, Colin Hockings, Cathrine Hall, Andrew J. Kueh, Michael T. Ryan, Ruth M. Kluck, Philippe Bouillet, Marco J. Herold, Daniel H.D. Gray, David C.S. Huang, Mark F. van Delft, Grant Dewson - Nature Communications 2018 cited by 192
- The Mitochondrial Apoptotic Effectors BAX/BAK Activate Caspase-3 and -7 to Trigger NLRP3 Inflammasome and Caspase-8 Driven IL-1β Activation
Authors: James E. Vince, Dominic De Nardo, Wenqing Gao, Angelina J. Vince, Cathrine Hall, Kate McArthur, Daniel S. Simpson, Swarna Lekha Vijayaraj, Lisa Lindqvist, Philippe Bouillet, Mark A. Rizzacasa, Si Ming Man, John Silke, Seth L. Masters, Guillaume Lessène, David C.S. Huang, Daniel H.D. Gray, Benjamin T. Kile, Feng Shao, Kate E. Lawlor - Cell Reports 2018 cited by 237
- LUBAC is essential for embryogenesis by preventing cell death and enabling haematopoiesis
Authors: Nieves Peltzer, Maurice Darding, Antonella Montinaro, Peter Dráber, Helena Draberova, Sebastian Kupka, Eva Rieser, Amanda Fisher, J. Ciaran Hutchinson, Lucia Taraborrelli, Torsten Hartwig, Élodie Lafont, Tobias L. Haas, Yutaka Shimizu, Charlotta Böiers, Aida Sarr, James Rickard, Silvia Álvarez-Díaz, Michael T. Ashworth, Allison M. Beal, Tariq Enver, John Bertin, William J. Kaiser, Andreas Strasser, John Silke, Philippe Bouillet, Henning Walczak - Nature 2018 cited by 211
- Proapoptotic Bcl-2 Relative Bim Required for Certain Apoptotic Responses, Leukocyte Homeostasis, and to Preclude Autoimmunity
Authors: Philippe Bouillet, Donald Metcalf, David C.S. Huang, David M. Tarlinton, Tom Kay, Frank Köntgen, Jerry M. Adams, Andreas Strasser - Science 1999 cited by 1,502
- Anti-apoptotic Mcl-1 is essential for the development and sustained growth of acute myeloid leukemia
Authors: Stefan Glaser, Erinna F. Lee, Evelyn Trounson, Philippe Bouillet, Andrew H. Wei, W. Douglas Fairlie, David J. Izon, Johannes Zuber, Amy Rappaport, Marco J. Herold, Warren S. Alexander, Scott W. Lowe, Lorraine Robb, Andreas Strasser - Genes & Development 2012 cited by 418
- DNA Damage-Induced Primordial Follicle Oocyte Apoptosis and Loss of Fertility Require TAp63-Mediated Induction of Puma and Noxa
Authors: J. B. Kerr, Karla J. Hutt, Ewa M. Michalak, Michele Cook, Cassandra J. Vandenberg, Seng H. Liew, Philippe Bouillet, Alea A. Mills, Clare L. Scott, Jock K. Findlay, Andreas Strasser - Molecular Cell 2012 cited by 267
- Anti-apoptotic proteins BCL-2, MCL-1 and A1 summate collectively to maintain survival of immune cell populations both in vitro and in vivo
Authors: Emma M. Carrington, Yifan Zhan, Jamie L. Brady, Jian‐Guo Zhang, Robyn M. Sutherland, Natasha S. Anstee, Robyn L. Schenk, Ingela B. Vikstrom, Rebecca B. Delconte, David Segal, Nicholas D. Huntington, Philippe Bouillet, David M. Tarlinton, David C.S. Huang, Andreas Strasser, Suzanne Cory, Marco J. Herold, Andrew M. Lew - Cell Death and Differentiation 2017 cited by 155
- Apoptosis initiated by Bcl-2-regulated caspase activation independently of the cytochrome c/Apaf-1/caspase-9 apoptosome
Authors: Vanessa S. Marsden, Liam O’Connor, Lorraine A. O’Reilly, John Silke, Donald Metcalf, Paul G. Ekert, David C.S. Huang, Francesco Cecconi, Keisuke Kuida, Kevin J. Tomaselli, Sophie Roy, D. W. Nicholson, David L. Vaux, Philippe Bouillet, Jerry M. Adams, Andreas Strasser - Nature 2002 cited by 587
- LUBAC prevents lethal dermatitis by inhibiting cell death induced by TNF, TRAIL and CD95L
Authors: Lucia Taraborrelli, Nieves Peltzer, Antonella Montinaro, Sebastian Kupka, Eva Rieser, Torsten Hartwig, Aida Sarr, Maurice Darding, Peter Dráber, Tobias L. Haas, Ayse U. Akarca, Teresa Marafioti, Manolis Pasparakis, John Bertin, Peter J. Gough, Philippe Bouillet, Andreas Strasser, Martin Leverkus, John Silke, Henning Walczak - Nature Communications 2018 cited by 101
- XIAP discriminates between type I and type II FAS-induced apoptosis
Authors: Philipp J. Jost, Stephanie Grabow, Daniel H.D. Gray, Mark McKenzie, Ueli Nachbur, David C.S. Huang, Philippe Bouillet, Helen E. Thomas, Christoph Borner, John Silke, Andreas Strasser, Thomas Kaufmann - Nature 2009 cited by 461
- BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes
Authors: Philippe Bouillet, Jared F. Purton, Dale I. Godfrey, Lichen Zhang, Leigh Coultas, Hamsa Puthalakath, Marc Pellegrini, Suzanne Cory, Jerry M. Adams, Andreas Strasser - Nature 2002 cited by 774
- Mcl-1 Is Essential for Germinal Center Formation and B Cell Memory
Authors: Ingela B. Vikstrom, Sebastian Carotta, Katja Lüthje, Victor Peperzak, Philipp J. Jost, Stefan Glaser, Meinrad Busslinger, Philippe Bouillet, Andreas Strasser, Stephen L. Nutt, David M. Tarlinton - Science 2010 cited by 216
- Apoptosis Initiated When BH3 Ligands Engage Multiple Bcl-2 Homologs, Not Bax or Bak
Authors: Simon N. Willis, Jamie I. Fletcher, Thomas Kaufmann, Mark F. van Delft, Lin Chen, Peter E. Czabotar, Helen Ierino, Erinna F. Lee, W. Douglas Fairlie, Philippe Bouillet, Andreas Strasser, Ruth M. Kluck, Jerry M. Adams, David C.S. Huang - Science 2007 cited by 1,109
- Two molecular pathways initiate mitochondria-dependent dopaminergic neurodegeneration in experimental Parkinson's disease
Authors: Céline Perier, Jordi Bové, Du‐Chu Wu, Benjamin Dehay, Dong‐Kug Choi, Vernice Jackson‐Lewis, Silvia Rathke‐Hartlieb, Philippe Bouillet, Andreas Strasser, Jörg B. Schulz, Serge Przedborski, Miquel Vila - National Academy of Sciences, Proceedings of the National Academy of Sciences 2007 cited by 228
- Antiapoptotic Mcl-1 is critical for the survival and niche-filling capacity of Foxp3+ regulatory T cells
Authors: Wim Pierson, Bénédicte Cauwe, Antonia N. Policheni, Susan Schlenner, Dean Franckaert, Julien Bergès, Stéphanie Humblet‐Baron, Susann Schönefeldt, Marco J. Herold, David A. Hildeman, Andreas Strasser, Philippe Bouillet, Li‐Fan Lu, Patrick Matthys, António A. Freitas, Rita J. Luther, Casey T. Weaver, James Dooley, Daniel H.D. Gray, Adrian Liston - Nature Immunology 2013 cited by 235
- Fas-mediated neutrophil apoptosis is accelerated by Bid, Bak, and Bax and inhibited by Bcl-2 and Mcl-1
Authors: Ben A. Croker, Joanne A. O’Donnell, Cameron J. Nowell, Donald Metcalf, Grant Dewson, Kirsteen J. Campbell, Kelly L. Rogers, Yifang Hu, Gordon K. Smyth, Jian‐Guo Zhang, M. J. D. White, Kurt Lackovic, Louise H. Cengia, Lorraine A. O’Reilly, Philippe Bouillet, Suzanne Cory, Andreas Strasser, Andrew W. Roberts - National Academy of Sciences, Proceedings of the National Academy of Sciences 2011 cited by 114
- Bim is a suppressor of Myc-induced mouse B cell leukemia
Authors: Alexander Egle, Alan W. Harris, Philippe Bouillet, Suzanne Cory - National Academy of Sciences, Proceedings of the National Academy of Sciences 2004 cited by 482
- Membrane-bound Fas ligand only is essential for Fas-induced apoptosis
Authors: Lorraine A. O’ Reilly, Lin Tai, Lily Lee, Elizabeth Kruse, Stephanie Grabow, W. Douglas Fairlie, Nicole M. Haynes, David M. Tarlinton, Jian‐Guo Zhang, Gabrielle T. Belz, Mark J. Smyth, Philippe Bouillet, Lorraine Robb, Andreas Strasser - Nature 2009 cited by 387
- BIM Regulates Apoptosis during Mammary Ductal Morphogenesis, and Its Absence Reveals Alternative Cell Death Mechanisms
Authors: Arnaud Mailleux, Michael Overholtzer, Tobias Schmelzle, Philippe Bouillet, Andreas Strasser, Joan S. Brugge - Developmental Cell 2007 cited by 233
- Apoptosis Regulators Fas and Bim Cooperate in Shutdown of Chronic Immune Responses and Prevention of Autoimmunity
Authors: Peter Hughes, Gabrielle T. Belz, Karen A. Fortner, Ralph C. Budd, Andreas Strasser, Philippe Bouillet - Immunity 2008 cited by 259
- Bcl-2, Bcl-xL, and Bcl-w are not equivalent targets of ABT-737 and navitoclax (ABT-263) in lymphoid and leukemic cells
Authors: Delphine Mérino, Seong Lin Khaw, Stefan Glaser, Daniel J. Anderson, Lisa D. Belmont, Chihunt Wong, Peng Yue, Mikara Robati, Belinda Phipson, W. Douglas Fairlie, Erinna F. Lee, Kirsteen J. Campbell, Cassandra J. Vandenberg, Suzanne Cory, Andrew W. Roberts, Mary J. C. Ludlam, David C.S. Huang, Philippe Bouillet - Blood 2012 cited by 191
- A tumor suppressor function for caspase-2
Authors: Lien H. Ho, Robyn Taylor, Loretta Dorstyn, Dimitrios Cakouros, Philippe Bouillet, Sharad Kumar - National Academy of Sciences, Proceedings of the National Academy of Sciences 2009 cited by 173
- The BH3-Only Proteins Bim and Puma Cooperate to Impose Deletional Tolerance of Organ-Specific Antigens
Authors: Daniel H.D. Gray, Fiona Kupresanin, Stuart P. Berzins, Marco J. Herold, Lorraine A. O’Reilly, Philippe Bouillet, Andreas Strasser - Immunity 2012 cited by 77
