Charles A. Dinarello
Active 1974–2024
- Also published as
- CHARLES A. DINARELLO
- 495
- Papers
- 137,684
- Citations
- 202
- h-index
- 492
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Medicine42.6%
- Biochemistry, Genetics and Molecular Biology23.9%
- Immunology and Microbiology18.4%
- Neuroscience8%
- Nursing2.3%
- Agricultural and Biological Sciences1.3%
- Other3.5%
Topics
- Inflammasome and immune disorders4.8%
- Immune Response and Inflammation3.6%
- Neuroinflammation and Neurodegeneration Mechanisms2.6%
- Immune Cell Function and Interaction2.3%
- Alzheimer's disease research and treatments1.9%
- Immune cells in cancer1.8%
- Other83%
Coauthors
- Leo A. B. Joosten58
- Mihai G. Netea48
- Giamila Fantuzzi35
- Tania Azam33
- Soohyun Kim28
- Frank L. van de Veerdonk24
- Joseph G. Cannon20
- J.W.M. van der Meer19
- Daniela Novick18
- Leonid L. Reznikov18
- Ron N. Apte18
- Philip Bufler17
- Carlo Marchetti16
- Elena Voronov15
- Eli C. Lewis15
- Isak W. Tengesdal15
- Paolo Mascagni15
- Marcel F. Nold14
- Soo Hyun Kim14
- Suzhao Li14
- Thomas Mandrup‐Poulsen14
- Xianzhong Meng14
- Dennis M. de Graaf13
- Giulio Cavalli12
All papers
- Neuroinflammation in Alzheimer's disease
Authors: Michael T. Heneka, Monica J. Carson, Joseph El Khoury, Gary E. Landreth, Frederic Brosseron, Douglas L. Feinstein, Andreas H. Jacobs, Tony Wyss‐Coray, Javier Vitórica, Richard M. Ransohoff, Karl Herrup, Sally A. Frautschy, Bente Finsen, Guy C. Brown, Alexei Verkhratsky, Koji Yamanaka, Jari Koıstınaho, Eicke Latz, Annett Halle, Gabor C. Petzold, Terrence Town, Dave Morgan, Mari L. Shinohara, V. Hugh Perry, Clive Holmes, Nicolás G. Bazán, David J. Brooks, Stéphane Hunot, Bertrand Joseph, Nikolaus Deigendesch, Olga Garaschuk, Erik Boddeke, Charles A. Dinarello, John C.S. Breitner, Greg M. Cole, Douglas T. Golenbock, Markus P. Kummer - The Lancet Neurology 2015 cited by 6,102
- Overview of the IL‐1 family in innate inflammation and acquired immunity
Authors: Charles A. Dinarello - Immunological Reviews 2017 cited by 1,828
- Interleukins in cancer: from biology to therapy
Authors: Daria Briukhovetska, Janina Dörr, Stefan Endres, Peter Libby, Charles A. Dinarello, Sebastian Kobold - Nature reviews. Cancer 2021 cited by 765
- Interleukin-1 and Related Cytokines in the Regulation of Inflammation and Immunity
Authors: Alberto Mantovani, Charles A. Dinarello, Martina Molgora, Cecília Garlanda - Immunity 2019 cited by 1,036
- Immunological and Inflammatory Functions of the Interleukin-1 Family
Authors: Charles A. Dinarello - Annual Review of Immunology 2009 cited by 3,432
- Interleukin-1 and the Inflammasome as Therapeutic Targets in Cardiovascular Disease
Authors: Antonio Abbate, Stefano Toldo, Carlo Marchetti, Jordana Kron, Benjamín W. Van Tassell, Charles A. Dinarello - Circulation Research 2020 cited by 714
- Interleukin-1 in the pathogenesis and treatment of inflammatory diseases
Authors: Charles A. Dinarello - Blood 2011 cited by 2,222
- Glutaminolysis and Fumarate Accumulation Integrate Immunometabolic and Epigenetic Programs in Trained Immunity
Authors: Rob J.W. Arts, Boris Novakovic, Rob ter Horst, Agostinho Carvalho, Siroon Bekkering, Ekta Lachmandas, Fernando Rodrigues, Ricardo Silvestre, Shih‐Chin Cheng, Shuang-Yin Wang, Ehsan Habibi, Luís G. Gonçalves, Inês Mesquita, Cristina Cunha, Arjan van Laarhoven, Frank L. van de Veerdonk, David L. Williams, J.W.M. van der Meer, Colin Logie, Luke O'neill, Charles A. Dinarello, Niels P. Riksen, Reinout van Crevel, Clary B. Clish, Richard A. Notebaart, Leo A. B. Joosten, Hendrik G. Stunnenberg, Ramnik J. Xavier, Mihai G. Netea - Cell Metabolism 2016 cited by 858
- OLT1177, a β-sulfonyl nitrile compound, safe in humans, inhibits the NLRP3 inflammasome and reverses the metabolic cost of inflammation
Authors: Carlo Marchetti, Benjamin J. Swartzwelter, Fabia Gamboni, C. Preston Neff, Katrin Richter, Tania Azam, Sonia Carta, Isak W. Tengesdal, Travis Nemkov, Angelo D’Alessandro, Curtis J. Henry, Gerald S. Jones, Scott A. Goodrich, Joseph P. St. Laurent, Terry M. Jones, Curtis L. Scribner, Robert B. Barrow, Roy D. Altman, Damaris B. Skouras, Marco Gattorno, Veronika Grau, Sabina Janciauskiene, Anna Rubartelli, Leo A. B. Joosten, Charles A. Dinarello - National Academy of Sciences, Proceedings of the National Academy of Sciences 2018 cited by 559
- The Interleukin-1 Family: Back to the Future
Authors: Cecília Garlanda, Charles A. Dinarello, Alberto Mantovani - Immunity 2013 cited by 1,918
- A guiding map for inflammation
Authors: Mihai G. Netea, Frances R. Balkwill, Michel Chonchol, Fabio Cominelli, Marc Y. Donath, Evangelos J. Giamarellos‐Bourboulis, Douglas T. Golenbock, Mark S. Gresnigt, Michael T. Heneka, Hal M. Hoffman, Richard S. Hotchkiss, Leo A. B. Joosten, Daniel L. Kastner, Martin Körte, Eicke Latz, Peter Libby, Thomas Mandrup‐Poulsen, Alberto Mantovani, Kingston H. G. Mills, Kristen L. Nowak, Luke O'neill, Peter Pickkers, Tom van der Poll, Paul M. Ridker, Joost Schalkwijk, David A. Schwartz, Britta Siegmund, Clifford J. Steer, Herbert Tilg, Jos W.M. van der Meer, Frank L. van de Veerdonk, Charles A. Dinarello - Nature Immunology 2017 cited by 823
- Treating inflammation by blocking interleukin-1 in a broad spectrum of diseases
Authors: Charles A. Dinarello, Anna Simon, Jos W.M. van der Meer - Nature Reviews Drug Discovery 2012 cited by 1,757
- Interleukin-1 Receptor Blockade Is Associated With Reduced Mortality in Sepsis Patients With Features of Macrophage Activation Syndrome
Authors: Bita Shakoory, Joseph A. Carcillo, W. Winn Chatham, Richard Amdur, Huaqing Zhao, Charles A. Dinarello, Randall Q. Cron, Steven M. Opal - Critical Care Medicine 2015 cited by 854
- The NLRP3 inflammasome inhibitor OLT1177 rescues cognitive impairment in a mouse model of Alzheimer’s disease
Authors: Niklas Lonnemann, Shirin Hosseini, Carlo Marchetti, Damaris B. Skouras, Davide Stefanoni, Angelo D’Alessandro, Charles A. Dinarello, Martin Körte - National Academy of Sciences, Proceedings of the National Academy of Sciences 2020 cited by 293
- Anti-inflammatory Agents: Present and Future
Authors: Charles A. Dinarello - Cell 2010 cited by 1,103
- Interleukin 1α: a comprehensive review on the role of IL-1α in the pathogenesis and treatment of autoimmune and inflammatory diseases
Authors: Giulio Cavalli, Serena Colafrancesco, Giacomo Emmi, Massimo Imazio, Giuseppe Lopalco, Maria Cristina Maggio, Jurgen Sota, Charles A. Dinarello - Autoimmunity Reviews 2021 cited by 331
- Targeting innate immune mediators in type 1 and type 2 diabetes
Authors: Marc Y. Donath, Charles A. Dinarello, Thomas Mandrup‐Poulsen - Nature reviews. Immunology 2019 cited by 418
- Blocking IL-1β reverses the immunosuppression in mouse breast cancer and synergizes with anti–PD-1 for tumor abrogation
Authors: Irena Kaplanov, Yaron Carmi, Rachel Kornetsky, Avishai Shemesh, Galina V. Shurin, Michael R. Shurin, Charles A. Dinarello, Elena Voronov, Ron N. Apte - National Academy of Sciences, Proceedings of the National Academy of Sciences 2018 cited by 437
- Dapansutrile, an oral selective NLRP3 inflammasome inhibitor, for treatment of gout flares: an open-label, dose-adaptive, proof-of-concept, phase 2a trial
Authors: Viola Klück, Tim Jansen, M. Janssen, Antoaneta Comarniceanu, M. Efdé, Isak W. Tengesdal, Kiki Schraa, Maartje C. P. Cleophas, Curtis L. Scribner, Damaris B. Skouras, Carlo Marchetti, Charles A. Dinarello, Leo A. B. Joosten - The Lancet Rheumatology 2020 cited by 290
- Proinflammatory Cytokines
Authors: Charles A. Dinarello - CHEST Journal 2000 cited by 2,020
- Interleukin-18 and IL-18 Binding Protein
Authors: Charles A. Dinarello, Daniela Novick, Soohyun Kim, Gilles Kaplanski - Frontiers in Immunology 2013 cited by 934
- Targeting tumor-derived NLRP3 reduces melanoma progression by limiting MDSCs expansion
Authors: Isak W. Tengesdal, Dinoop Ravindran Menon, Douglas G. Osborne, C. Preston Neff, Nicholas E. Powers, Fabia Gamboni, Adolfo G Mauro, Angelo D’Alessandro, Davide Stefanoni, Morkos A. Henen, Taylor Mills, Dennis M. de Graaf, Tania Azam, Beat Vögeli, Brent E. Palmer, Eric M. Pietras, James DeGregori, Aik Choon Tan, Leo A. B. Joosten, Mayumi Fujita, Charles A. Dinarello, Carlo Marchetti - National Academy of Sciences, Proceedings of the National Academy of Sciences 2021 cited by 193
- The IL-1 family of cytokines and receptors in rheumatic diseases
Authors: Charles A. Dinarello - Nature Reviews Rheumatology 2019 cited by 367
- OLT1177 (Dapansutrile), a Selective NLRP3 Inflammasome Inhibitor, Ameliorates Experimental Autoimmune Encephalomyelitis Pathogenesis
Authors: Alba Sánchez‐Fernández, Damaris B. Skouras, Charles A. Dinarello, Rubén López‐Vales - Frontiers in Immunology 2019 cited by 166
