David L. Williams
Active 1970–2025
- 238
- Papers
- 41,012
- Citations
- 118
- h-index
- 233
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Medicine36.2%
- Immunology and Microbiology23%
- Biochemistry, Genetics and Molecular Biology21.5%
- Neuroscience5.6%
- Agricultural and Biological Sciences4.8%
- Social Sciences2.7%
- Other6.2%
Topics
- Immune Response and Inflammation2.8%
- Immune cells in cancer2.6%
- Antifungal resistance and susceptibility2.4%
- Immune responses and vaccinations2.2%
- Polysaccharides and Plant Cell Walls1.8%
- Fungal Infections and Studies1.8%
- Other86.4%
Coauthors
- Chuanfu Li35
- Tuanzhu Ha34
- John H. Kalbfleisch23
- Gordon D. Brown22
- Xiaohui Wang21
- I. William Browder18
- Li Liu18
- Harry E. Ensley17
- Jim Kelley17
- Race L. Kao17
- Margery A. Connelly15
- Siamon Gordon14
- Douglas W. Lowman13
- Janet A. Willment12
- Peter J. Rice12
- Mihai G. Netea11
- Min Fan11
- Fei Tu10
- Kun Yang10
- Michael C. Phillips10
- George H. Rothblat9
- James L. Ritchie9
- Margarita de la Llera-Moya9
- Xiang Gao9
All papers
- Lactate promotes macrophage HMGB1 lactylation, acetylation, and exosomal release in polymicrobial sepsis
Authors: Kun Yang, Min Fan, Xiaohui Wang, Jingjing Xu, Yana Wang, Fei Tu, Parkash S. Gill, Tuanzhu Ha, Li Liu, David L. Williams, Chuanfu Li - Cell Death and Differentiation 2021 cited by 749
- Lactate promotes endothelial-to-mesenchymal transition via Snail1 lactylation after myocardial infarction
Authors: Min Fan, Kun Yang, Xiaohui Wang, Linjian Chen, Parkash S. Gill, Tuanzhu Ha, Li Liu, Nicole Lewis, David L. Williams, Chuanfu Li - Science Advances 2023 cited by 366
- Glutaminolysis and Fumarate Accumulation Integrate Immunometabolic and Epigenetic Programs in Trained Immunity
Authors: Rob J.W. Arts, Boris Novakovic, Rob ter Horst, Agostinho Carvalho, Siroon Bekkering, Ekta Lachmandas, Fernando Rodrigues, Ricardo Silvestre, Shih‐Chin Cheng, Shuang-Yin Wang, Ehsan Habibi, Luís G. Gonçalves, Inês Mesquita, Cristina Cunha, Arjan van Laarhoven, Frank L. van de Veerdonk, David L. Williams, J.W.M. van der Meer, Colin Logie, Luke O'neill, Charles A. Dinarello, Niels P. Riksen, Reinout van Crevel, Clary B. Clish, Richard A. Notebaart, Leo A. B. Joosten, Hendrik G. Stunnenberg, Ramnik J. Xavier, Mihai G. Netea - Cell Metabolism 2016 cited by 858
- Trained immunity, tolerance, priming and differentiation: distinct immunological processes
Authors: Maziar Divangahi, Peter Aaby, Shabaana A. Khader, Luis B. Barreiro, Siroon Bekkering, Triantafyllos Chavakis, Reinout van Crevel, Nigel Curtis, Andrew R. DiNardo, Jorge Domínguez‐Andrés, Raphaël Duivenvoorden, Stephanie Fanucchi, Zahi A. Fayad, Elaine Fuchs, Mélanie Hamon, Kate L. Jeffrey, Nargis Khan, Leo A. B. Joosten, Eva Kaufmann, Eicke Latz, Giuseppe Matarese, J.W.M. van der Meer, Musa M. Mhlanga, Simone J.C.F.M. Moorlag, Willem J. M. Mulder, Shruti Naik, Boris Novakovic, Luke O'neill, Jordi Ochando, Keiko Ozato, Niels P. Riksen, Robert W. Sauerwein, Edward R. Sherwood, Andreas Schlitzer, Joachim L. Schultze, Michael H. Sieweke, Christine Stabell Benn, Henk G. Stunnenberg, Joseph C. Sun, Frank L. van de Veerdonk, Sebastian Weis, David L. Williams, Ramnik J. Xavier, Mihai G. Netea - Nature Immunology 2020 cited by 595
- Lactate Suppresses Macrophage Pro-Inflammatory Response to LPS Stimulation by Inhibition of YAP and NF-κB Activation via GPR81-Mediated Signaling
Authors: Kun Yang, Jingjing Xu, Min Fan, Fei Tu, Xiaohui Wang, Tuanzhu Ha, David L. Williams, Chuanfu Li - Frontiers in Immunology 2020 cited by 263
- Why people use social media: a uses and gratifications approach
Authors: Anita Whiting, David L. Williams - Qualitative Market Research An International Journal 2013 cited by 1,753
- Inflammatory Type 2 cDCs Acquire Features of cDC1s and Macrophages to Orchestrate Immunity to Respiratory Virus Infection
Authors: Cédric Bosteels, Katrijn Neyt, Manon Vanheerswynghels, Mary J. van Helden, Dorine Sichien, Nincy Debeuf, Sofie De Prijck, Victor Bosteels, Niels Vandamme, Liesbet Martens, Yvan Saeys, Els Louagie, Manon Lesage, David L. Williams, Shiau‐Choot Tang, Johannes U. Mayer, Franca Ronchese, Charlotte L. Scott, Hamida Hammad, Martin Guilliams, Bart N. Lambrecht - Immunity 2020 cited by 408
- Aorta- and liver-generated TMAO enhances trained immunity for increased inflammation via ER stress/mitochondrial ROS/glycolysis pathways
Authors: Fatma Saaoud, Lu Liu, Keman Xu, Ramón Cueto, Ying Shao, Yifan Lu, Yu Sun, Nathaniel W. Snyder, Sheng Wu, Ling Yang, Yan Zhou, David L. Williams, Chuanfu Li, Laisel Martinez, Roberto I. Vázquez-Padrón, Huaqing Zhao, Xiaohua Jiang, Hong Wang, Xiaofeng Yang - JCI Insight 2022 cited by 133
- Lactate induces vascular permeability via disruption of VE-cadherin in endothelial cells during sepsis
Authors: Kun Yang, Min Fan, Xiaohui Wang, Jingjing Xu, Yana Wang, Parkash S. Gill, Tuanzhu Ha, Li Liu, Jennifer V. Hall, David L. Williams, Chuanfu Li - Science Advances 2022 cited by 160
- Trained Immunity or Tolerance: Opposing Functional Programs Induced in Human Monocytes after Engagement of Various Pattern Recognition Receptors
Authors: Daniela C. Ifrim, Jessica Quintin, Leo A. B. Joosten, Cor Jacobs, Trees Jansen, Liesbeth Jacobs, Neil A. R. Gow, David L. Williams, J.W.M. van der Meer, Mihai G. Netea - Clinical and Vaccine Immunology 2014 cited by 354
- Dectin-1 Is A Major β-Glucan Receptor On Macrophages
Authors: Gordon D. Brown, Philip R. Taylor, Delyth M. Reid, Janet A. Willment, David L. Williams, Luisa Martínez‐Pomares, Simon Y. C. Wong, Siamon Gordon - The Journal of Experimental Medicine 2002 cited by 1,003
- Tissue-Specific Macrophage Responses to Remote Injury Impact the Outcome of Subsequent Local Immune Challenge
Authors: Friedrich Felix Hoyer, Kamila Naxerova, Maximilian J. Schloss, Maarten Hulsmans, Anil V. Nair, Partha Dutta, David Calcagno, Fanny Hérisson, Atsushi Anzai, Yuan Sun, Gregory R. Wojtkiewicz, David Rohde, Vanessa Frodermann, Katrien Vandoorne, Gabriel Courties, Yoshiko Iwamoto, Christopher Garris, David L. Williams, Sylvie Breton, Dennis Brown, Michael J. Whalen, Peter Libby, Mikaël J. Pittet, Kevin R. King, Ralph Weissleder, Filip K. Świrski, Matthias Nahrendorf - Immunity 2019 cited by 178
- Dectin-1 Mediates the Biological Effects of β-Glucans
Authors: Gordon D. Brown, Jürgen Herre, David L. Williams, Janet A. Willment, Andrew S. J. Marshall, Siamon Gordon - The Journal of Experimental Medicine 2003 cited by 1,199
- Lactate and Immunosuppression in Sepsis
Authors: Benjamin Nolt, Fei Tu, Xiaohui Wang, Tuanzhu Ha, Randi Winter, David L. Williams, Chuanfu Li - Shock 2017 cited by 237
- An adjuvant strategy enabled by modulation of the physical properties of microbial ligands expands antigen immunogenicity
Authors: Francesco Borriello, Valentina Poli, Ellen Shrock, Roberto Spreafico, Xin Liu, Novalia Pishesha, Claire Carpenet, Janet Chou, Marco Di Gioia, Marisa E. McGrath, Carly Dillen, Nora A. Barrett, Lucrezia Lacanfora, Marcella E. Franco, Laura Marongiu, Yoichiro Iwakura, Ferdinando Pucci, Michael Kruppa, Zuchao Ma, Douglas W. Lowman, Harry E. Ensley, Etsuro Nanishi, Yoshine Saito, Timothy R. O’Meara, Hyuk‐Soo Seo, Sirano Dhe‐Paganon, David J. Dowling, Matthew B. Frieman, Stephen J. Elledge, Ofer Levy, Darrell J. Irvine, Hidde L. Ploegh, David L. Williams, Ivan Zanoni - Cell 2022 cited by 127
- β-Glucan Induces Distinct and Protective Innate Immune Memory in Differentiated Macrophages
Authors: Cody L. Stothers, Katherine R. Burelbach, Allison M. Owen, Naeem K. Patil, Margaret A. McBride, Julia K. Bohannon, Liming Luan, Antonio Hernandez, Tazeen K Patil, David L. Williams, Edward R. Sherwood - The Journal of Immunology 2021 cited by 105
- Syk-Dependent Cytokine Induction by Dectin-1 Reveals a Novel Pattern Recognition Pathway for C Type Lectins
Authors: Neil C. Rogers, Emma Slack, Alexander D. Edwards, Martijn A. Nolte, Oliver Schulz, Edina Schweighoffer, David L. Williams, Siamon Gordon, Victor L. J. Tybulewicz, Gordon D. Brown, Caetano Reis e Sousa - Immunity 2005 cited by 881
- Differential High-Affinity Interaction of Dectin-1 with Natural or Synthetic Glucans Is Dependent upon Primary Structure and Is Influenced by Polymer Chain Length and Side-Chain Branching
Authors: Elizabeth L. Adams, Peter J. Rice, Bridget Graves, Harry E. Ensley, Hai Yu, Gordon D. Brown, Siamon Gordon, Mário A. Monteiro, Erzsēbet Papp-Szabó, Douglas W. Lowman, Trevor D. Power, Michael F. Wempe, David L. Williams - Journal of Pharmacology and Experimental Therapeutics 2008 cited by 297
- Enhanced Glycolytic Metabolism Contributes to Cardiac Dysfunction in Polymicrobial Sepsis
Authors: Zhibo Zheng, He Ma, Xia Zhang, Fei Tu, Xiaohui Wang, Tuanzhu Ha, Min Fan, Li Liu, Jingjing Xu, Kaijiang Yu, Ruitao Wang, John H. Kalbfleisch, Race L. Kao, David L. Williams, Chuanfu Li - The Journal of Infectious Diseases 2017 cited by 159
- Novel Role of Endothelial Derived Exosomal HSPA12B in Regulating Macrophage Inflammatory Responses in Polymicrobial Sepsis
Authors: Fei Tu, Xiaohui Wang, Xia Zhang, Tuanzhu Ha, Yana Wang, Min Fan, Kun Yang, Parkash S. Gill, Tammy R. Ozment, Yuan Dai, Li Liu, David L. Williams, Chuanfu Li - Frontiers in Immunology 2020 cited by 59
- Human Dectin-1 Deficiency and Mucocutaneous Fungal Infections
Authors: Bart Ferwerda, Gerben Ferwerda, Theo S. Plantinga, Janet A. Willment, Annemiek B. van Spriel, Hanka Venselaar, Clara C. Elbers, Melissa D. Johnson, Alessandra Cambi, Cristal Huysamen, Liesbeth Jacobs, Trees Jansen, Karlijn Verheijen, L. J. Masthoff, Servaas A. Morré, Gert Vriend, David L. Williams, John R. Perfect, Leo A. B. Joosten, Cisca Wijmenga, J.W.M. van der Meer, Gosse J. Adema, Bart Jan Kullberg, Gordon D. Brown, Mihai G. Netea - New England Journal of Medicine 2009 cited by 743
- Innate Immune Memory and the Host Response to Infection
Authors: Edward R. Sherwood, Katherine R. Burelbach, Margaret A. McBride, Cody L. Stothers, Allison M. Owen, Antonio Hernandez, Naeem K. Patil, David L. Williams, Julia K. Bohannon - The Journal of Immunology 2022 cited by 93
- Transcriptional and functional insights into the host immune response against the emerging fungal pathogen Candida auris
Authors: Mariolina Bruno, Simone Kersten, Judith M. Bain, Martin Jaeger, Diletta Rosati, Michael Kruppa, Douglas W. Lowman, Peter J. Rice, Bridget Graves, Zuchao Ma, Yue Ning Jiao, Anuradha Chowdhary, George Renieris, Frank L. van de Veerdonk, Bart Jan Kullberg, Evangelos J. Giamarellos‐Bourboulis, Alexander Hoischen, Neil A. R. Gow, Alistair J. P. Brown, Jacques F. Meis, David L. Williams, Mihai G. Netea - Nature Microbiology 2020 cited by 139
- Immunoregulatory Activity of the Natural Product Laminarin Varies Widely as a Result of Its Physical Properties
Authors: Alyson Smith, Bridget Graves, Robert Child, Peter J. Rice, Zuchao Ma, Douglas W. Lowman, Harry E. Ensley, Kendal Ryter, Jay T. Evans, David L. Williams - The Journal of Immunology 2017 cited by 86
