Matthew A. Cooper
Active 1980–2025
- Also published as
- Matthew A Cooper
- 143
- Papers
- 30,696
- Citations
- 86
- h-index
- 140
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Biochemistry, Genetics and Molecular Biology42.3%
- Medicine31.8%
- Immunology and Microbiology10.1%
- Neuroscience3.7%
- Engineering2.1%
- Agricultural and Biological Sciences1.9%
- Other8.1%
Topics
- Inflammasome and immune disorders8.3%
- Gut microbiota and health2.6%
- Antibiotic Resistance in Bacteria1.7%
- Neuroinflammation and Neurodegeneration Mechanisms1.7%
- Antimicrobial Peptides and Activities1.6%
- Acute Myeloid Leukemia Research1.3%
- Other82.8%
Coauthors
- Mark A. T. Blaskovich42
- Avril A. B. Robertson30
- Alysha G. Elliott22
- Mark S. Butler21
- Johannes Zuegg14
- Johnny X. Huang12
- Luke O'neill11
- Kate Schroder8
- Philip M. Hansbro8
- Angela M. Kavanagh7
- Jay C. Horvat7
- Karl A. Hansford7
- Tony Velkov7
- Jian Li6
- Richard Kim6
- Trent M. Woodruff6
- Wanida Phetsang6
- Zyta M. Ziora6
- Eicke Latz5
- Hanna E. Sidjabat5
- J. Alex Grizzell5
- James Pinkerton5
- M. Rhia L. Stone5
- Roger L. Nation5
All papers
- A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases
Authors: Rebecca C. Coll, Avril A. B. Robertson, Jae Jin Chae, Sarah Higgins, Raúl Muñoz-Planillo, Marco Inserra, Irina Vetter, Lara S. Dungan, Brian G. Monks, Andrea Stutz, Daniel E. Croker, Mark S. Butler, Moritz Haneklaus, Caroline E. Sutton, Gabriel Núñez, Eicke Latz, Daniel L. Kastner, Kingston H. G. Mills, Seth L. Masters, Kate Schroder, Matthew A. Cooper, Luke O'neill - Nature Medicine 2015 cited by 2,784
- Clonal hematopoiesis associated with TET2 deficiency accelerates atherosclerosis development in mice
Authors: José J. Fuster, Susan MacLauchlan, María A. Zuriaga, Maya N. Polackal, Allison C. Ostriker, Raja Chakraborty, Chia-Ling Wu, Soichi Sano, Sujatha Muralidharan, Cristina Rius, Jacqueline Vuong, Sophia Jacob, Varsha Muralidhar, Avril A. B. Robertson, Matthew A. Cooper, Vicente Andrés, Karen K. Hirschi, Kathleen A. Martin, Kenneth Walsh - Science 2017 cited by 1,531
- Emerging pathogenic links between microbiota and the gut–lung axis
Authors: Kurtis F. Budden, Shaan L. Gellatly, David Wood, Matthew A. Cooper, Mark Morrison, Philip Hugenholtz, Philip M. Hansbro - Nature Reviews Microbiology 2016 cited by 1,572
- NLRP3 inflammasome blockade reduces liver inflammation and fibrosis in experimental NASH in mice
Authors: Auvro R. Mridha, Alexander Wree, Avril A. B. Robertson, Matthew M. Yeh, Casey D. Johnson, Derrick M. Van Rooyen, Fahrettin Haczeyni, Narci Teoh, Christopher Savard, George N. Ioannou, Seth L. Masters, Kate Schroder, Matthew A. Cooper, Ariel E. Feldstein, Geoffrey C. Farrell - Journal of Hepatology 2017 cited by 1,070
- Inflammasome inhibition prevents α-synuclein pathology and dopaminergic neurodegeneration in mice
Authors: Richard D. Gordon, Eduardo A. Albornoz, Daniel C. Christie, Monica R. Langley, Vinod Kumar, Susanna Mantovani, Avril A. B. Robertson, Mark S. Butler, Dominic B. Rowe, Luke O'neill, Anumantha G. Kanthasamy, Kate Schroder, Matthew A. Cooper, Trent M. Woodruff - Science Translational Medicine 2018 cited by 890
- Tet2-Mediated Clonal Hematopoiesis Accelerates Heart Failure Through a Mechanism Involving the IL-1β/NLRP3 Inflammasome
Authors: Soichi Sano, Kosei Oshima, Ying Wang, Susan MacLauchlan, Yasufumi Katanasaka, Miho Sano, María A. Zuriaga, Minoru Yoshiyama, David A. Goukassian, Matthew A. Cooper, José J. Fuster, Kenneth Walsh - Journal of the American College of Cardiology 2018 cited by 677
- Inhibiting the NLRP3 inflammasome with MCC950 promotes non-phlogistic clearance of amyloid-β and cognitive function in APP/PS1 mice
Authors: Colin Dempsey, A. Rubio Araiz, Karen Bryson, Orla M. Finucane, Caroline M. Larkin, Evanna L. Mills, Avril A. B. Robertson, Matthew A. Cooper, Luke O'neill, Marina A. Lynch - Brain Behavior and Immunity 2016 cited by 568
- Human Monocytes Engage an Alternative Inflammasome Pathway
Authors: Moritz M. Gaidt, Thomas S. Ebert, Dhruv Chauhan, Tobias Schmidt, Jonathan L. Schmid‐Burgk, Francesca Rapino, Avril A. B. Robertson, Matthew A. Cooper, Thomas Graf, Veit Hornung - Immunity 2016 cited by 760
- K + Efflux-Independent NLRP3 Inflammasome Activation by Small Molecules Targeting Mitochondria
Authors: Christina J. Groß, Ritu Mishra, Katharina S. Schneider, Guillaume Médard, Jennifer Wettmarshausen, Daniela Dittlein, Hexin Shi, Oliver Gorka, Paul-Albert Koenig, Stephan Fromm, Giovanni Magnani, Tamara Ćiković, Lara Hartjes, Joachim Smollich, Avril A. B. Robertson, Matthew A. Cooper, Marc Schmidt‐Supprian, Michael Schuster, Kate Schroder, Petr Brož, Claudia Traidl‐Hoffmann, Bruce Beutler, Bernhard Küster, Jürgen Ruland, Sabine Schneider, Fabiana Perocchi, Olaf Groß - Immunity 2016 cited by 523
- Metal complexes as a promising source for new antibiotics
Authors: Angelo Frei, Johannes Zuegg, Alysha G. Elliott, Murray V. Baker, Stefan Braese, Christopher A. Brown, Feng Chen, Christopher G. Dowson, Gilles Dujardin, Nicole Jung, Anna King, Ahmed M. Mansour, Massimiliano Massi, John Moat, Heba Mohamed, Anna K. Renfrew, Peter J. Rutledge, Peter J. Sadler, Matthew H. Todd, Charlotte E. Willans, Justin J. Wilson, Matthew A. Cooper, Mark A. T. Blaskovich - Chemical Science 2020 cited by 513
- T helper 1 immunity requires complement-driven NLRP3 inflammasome activity in CD4 + T cells
Authors: Giuseppina Arbore, Erin E. West, Rosanne Spolski, Avril A. B. Robertson, Andreas Klos, Claudia Rheinheimer, Pavel Dutow, Trent M. Woodruff, Zu Xi Yu, Luke O'neill, Rebecca C. Coll, Alan Sher, Warren J. Leonard, Jörg Köhl, Peter N. Monk, Matthew A. Cooper, Matthew Arno, Behdad Afzali, Helen J. Lachmann, Andrew P. Cope, Katrin D. Mayer-Barber, Claudia Kemper - Science 2016 cited by 511
- NLRP3 inflammasome activation downstream of cytoplasmic LPS recognition by both caspase‐4 and caspase‐5
Authors: Paul J. Baker, Dave Boucher, Damiën Bierschenk, Christina Tebartz, Paul G. Whitney, Damian B. D’Silva, Maria C. Tanzer, Mercedes Monteleone, Avril A. B. Robertson, Matthew A. Cooper, Silvia Álvarez-Díaz, Marco J. Herold, Sammy Bedoui, Kate Schroder, Seth L. Masters - European Journal of Immunology 2015 cited by 356
- Pharmacological inhibition of the NLRP3 inflammasome reduces blood pressure, renal damage, and dysfunction in salt-sensitive hypertension
Authors: Shalini M Krishnan, Yeong Hann Ling, Brooke M. Huuskes, Dorota Ferens, Narbada Saini, Christopher T. Chan, Henry Diep, Michelle M. Kett, Chrishan S. Samuel, Barbara K. Kemp‐Harper, Avril A. B. Robertson, Matthew A. Cooper, Karlheinz Peter, Eicke Latz, Ashley Mansell, Christopher G. Sobey, Grant R. Drummond, Antony Vinh - Cardiovascular Research 2018 cited by 269
- Role for NLRP3 Inflammasome–mediated, IL-1β–Dependent Responses in Severe, Steroid-Resistant Asthma
Authors: Richard Kim, James Pinkerton, Ama‐Tawiah Essilfie, Avril A. B. Robertson, Katherine J. Baines, Alexandra C. Brown, Jemma Mayall, Md Khadem Ali, Malcolm R. Starkey, Nicole G. Hansbro, Jeremy A. Hirota, Lisa G. Wood, Jodie L. Simpson, Darryl A. Knight, Peter Wark, Peter G. Gibson, Luke O'neill, Matthew A. Cooper, Jay C. Horvat, Philip M. Hansbro - American Journal of Respiratory and Critical Care Medicine 2017 cited by 435
- Genomic characterization of the uncultured Bacteroidales family S24-7 inhabiting the guts of homeothermic animals
Authors: Kate L. Ormerod, David Wood, Nancy Lachner, Shaan L. Gellatly, Joshua Daly, Jeremy Parsons, Cristiana G. O. Dal’Molin, Robin Palfreyman, Lars K. Nielsen, Matthew A. Cooper, Mark Morrison, Philip M. Hansbro, Philip Hugenholtz - Microbiome 2016 cited by 694
- The NLRP3 inflammasome functions as a driver of the myelodysplastic syndrome phenotype
Authors: Ashley A. Basiorka, Kathy L. McGraw, Erika A. Eksioglu, Xianghong Chen, Joseph Johnson, Ling Zhang, Qing Zhang, Brittany Irvine, Thomas Cluzeau, David A. Sallman, Eric Padron, Rami S. Komrokji, Lubomir Sokol, Rebecca C. Coll, Avril A. B. Robertson, Matthew A. Cooper, John L. Cleveland, Luke O'neill, Sheng Wei, Alan F. List - Blood 2016 cited by 346
- Myeloid-derived miR-223 regulates intestinal inflammation via repression of the NLRP3 inflammasome
Authors: Viola Neudecker, Moritz Haneklaus, Owen Jensen, Ludmila Khailová, Joanne C. Masterson, Hazel Tye, Kathryn A. Biette, Paul Jedlicka, Kelley S. Brodsky, Mark E. Gerich, Matthias Mack, Avril A. B. Robertson, Matthew A. Cooper, Glenn T. Furuta, Charles A. Dinarello, Luke O'neill, Holger K. Eltzschig, Seth L. Masters, Eóin N. McNamee - The Journal of Experimental Medicine 2017 cited by 359
- Pharmacological Inhibition of the Nod-Like Receptor Family Pyrin Domain Containing 3 Inflammasome with MCC950
Authors: Sarah E. Corcoran, Reena Halai, Matthew A. Cooper - Pharmacological Reviews 2021 cited by 164
- The microglial NLRP3 inflammasome is activated by amyotrophic lateral sclerosis proteins
Authors: Vandana Deora, John D. Lee, Eduardo A. Albornoz, Luke McAlary, Cyril J. Jagaraj, Avril A. B. Robertson, Julie D. Atkin, Matthew A. Cooper, Kate Schroder, Justin J. Yerbury, Richard D. Gordon, Trent M. Woodruff - Glia 2019 cited by 234
- TET2-Loss-of-Function-Driven Clonal Hematopoiesis Exacerbates Experimental Insulin Resistance in Aging and Obesity
Authors: José J. Fuster, María A. Zuriaga, Virginia Zorita, Susan MacLauchlan, Maya N. Polackal, Vanesa Viana‐Huete, Alba Ferrer-Pérez, Nuria Matesanz, Andrea Herrero-Cervera, Soichi Sano, Matthew A. Cooper, Herminia González‐Navarro, Kenneth Walsh - Cell Reports 2020 cited by 203
- An amphipathic peptide with antibiotic activity against multidrug-resistant Gram-negative bacteria
Authors: Alysha G. Elliott, Johnny X. Huang, Søren Neve, Johannes Zuegg, Ingrid A. Edwards, Amy K. Cain, Christine J. Boinett, Lars Barquist, Carina Vingsbo Lundberg, Jason A. Steen, Mark S. Butler, Mehdi Mobli, Kaela M. Porter, Mark A. T. Blaskovich, Sergio Lociuro, Magnus Strandh, Matthew A. Cooper - Nature Communications 2020 cited by 197
- Interleukin-1β suppression dampens inflammatory leucocyte production and uptake in atherosclerosis
Authors: Jan Hettwer, Julia Hinterdobler, Benedikt Miritsch, Marcus-André Deutsch, Xinghai Li, Carina Mauersberger, Aldo Moggio, Quinte Braster, Hermann Gram, Avril A. B. Robertson, Matthew A. Cooper, Olaf Groß, Markus Krane, Christian Weber, Wolfgang Köenig, Oliver Soehnlein, Nicholas H. Adamstein, Paul M. Ridker, Heribert Schunkert, Peter Libby, Thorsten Kessler, Hendrik B. Sager - Cardiovascular Research 2021 cited by 104
- The selective NLRP3-inflammasome inhibitor MCC950 reduces infarct size and preserves cardiac function in a pig model of myocardial infarction
Authors: Gerardus P. J. van Hout, Lena Bosch, Guilielmus H.J.M. Ellenbroek, Judith J. de Haan, Wouter W. van Solinge, Matthew A. Cooper, Fatih Arslan, Saskia C.A. de Jager, Avril A. B. Robertson, Gerard Pasterkamp, Imo E. Hoefer - European Heart Journal 2016 cited by 322
- Targeting the NLRP3 Inflammasome With Inhibitor MCC950 Prevents Aortic Aneurysms and Dissections in Mice
Authors: Pingping Ren, Darrell Wu, Richard G. Appel, Lin Zhang, Chen Zhang, Wei Luo, Avril A. B. Robertson, Matthew A. Cooper, Joseph S. Coselli, Dianna M. Milewicz, Ying H. Shen, Scott A. LeMaire - Journal of the American Heart Association 2020 cited by 117
