Padraic G. Fallon
Active 1994–2025
- 123
- Papers
- 25,179
- Citations
- 84
- h-index
- 121
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Immunology and Microbiology44.2%
- Medicine33.2%
- Biochemistry, Genetics and Molecular Biology17.3%
- Neuroscience2.2%
- Nursing0.5%
- Agricultural and Biological Sciences0.5%
- Other2.1%
Topics
- IL-33, ST2, and ILC Pathways8.8%
- Immune Cell Function and Interaction7.7%
- Eosinophilic Esophagitis4.3%
- Asthma and respiratory diseases4.1%
- Dermatology and Skin Diseases3.7%
- Immune cells in cancer3.1%
- Other68.3%
Coauthors
- Andrew N. J. McKenzie33
- Emily Hams29
- Sean P. Saunders16
- Helen E. Jolin13
- Niamh E. Mangan11
- Christian Schwartz10
- Philip Smith9
- Alan D. Irvine8
- Patrick Walsh7
- Achilleas Floudas6
- Cormac T. Taylor6
- Eoin P. Cummins6
- Luke O'neill6
- Adrien Kissenpfennig5
- Aisling O’Halloran5
- Andrew E. Hogan5
- Graham S. Ogg5
- Heike C. Hawerkamp5
- Jillian L. Barlow5
- Rose Anne Kenny5
- Sylvie Amu5
- Tara Moran5
- Yasmina Hernandez-Santana5
- Claire Emson4
All papers
- Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1
Authors: Evanna L. Mills, Dylan G. Ryan, Hiran A. Prag, Dina Dikovskaya, Deepthi Menon, Zbigniew Zasłona, Mark P. Jedrychowski, Ana S.H. Costa, Maureen Higgins, Emily Hams, John Szpyt, Marah C. Runtsch, Martin King, Joanna F. McGouran, Román Fischer, Benedikt M. Kessler, Anne F. McGettrick, Mark Hughes, Richard G. Carroll, Lee M. Booty, Elena V. Knatko, Paul J. Meakin, Michael L.J. Ashford, Louise K. Modis, Gino Brunori, Daniel C. Sévin, Padraic G. Fallon, Stuart T. Caldwell, Edmund R.S. Kunji, Edward T. Chouchani, Christian Frezza, Albena T. Dinkova‐Kostova, Richard C. Hartley, Michael P. Murphy, Luke O'neill - Nature 2018 cited by 1,905
- Itaconate and itaconate derivatives target JAK1 to suppress alternative activation of macrophages
Authors: Marah C. Runtsch, Stefano Angiari, Alexander Hooftman, Ridhima Wadhwa, Yanling Zhang, Yunan Zheng, Joseph S. Spina, Melanie C. Ruzek, M.A. Argiriadi, Anne F. McGettrick, Rui Santalla Méndez, Alessia Zotta, Christian G. Peace, Aoife Walsh, Roberta Chirillo, Emily Hams, Padraic G. Fallon, Ranjith Jayaraman, Kamal Dua, Alexandra C. Brown, Richard Kim, Jay C. Horvat, Philip M. Hansbro, Chu Wang, Luke O'neill - Cell Metabolism 2022 cited by 318
- Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity
Authors: Daniel R. Neill, See Heng Wong, Agustin Bellosi, Robin J. Flynn, Maria Daly, Theresa K. A. Langford, Christine M. Bucks, Colleen Kane, Padraic G. Fallon, Richard Pannell, Helen E. Jolin, Andrew N. J. McKenzie - Nature 2010 cited by 2,067
- The alarmin IL-33 promotes regulatory T-cell function in the intestine
Authors: Chris Schiering, Thomas Krausgruber, Agnieszka Chomka, Anja Fröhlich, Krista Adelmann, Elizabeth A. Wohlfert, Johanna Pott, Thibault Griseri, Julia Bollrath, Ahmed N. Hegazy, Oliver J. Harrison, Benjamin M. J. Owens, Max Löhning, Yasmine Belkaid, Padraic G. Fallon, Fiona Powrie - Nature 2014 cited by 1,015
- A role for IL-25 and IL-33–driven type-2 innate lymphoid cells in atopic dermatitis
Authors: Maryam Salimi, Jillian L. Barlow, Sean P. Saunders, Luzheng Xue, Danuta Gutowska‐Owsiak, Xinwen Wang, Li-Chieh Huang, David Johnson, Seth Thomas Scanlon, Andrew N. J. McKenzie, Padraic G. Fallon, Graham S. Ogg - The Journal of Experimental Medicine 2013 cited by 952
- Tumor PD-L1 engages myeloid PD-1 to suppress type I interferon to impair cytotoxic T lymphocyte recruitment
Authors: John D. Klement, Priscilla S. Redd, Chunwan Lu, Alyssa D. Merting, Dakota B. Poschel, Dafeng Yang, Natasha M. Savage, Gang Zhou, David H. Munn, Padraic G. Fallon, Kebin Liu - Cancer Cell 2023 cited by 119
- MHCII-Mediated Dialog between Group 2 Innate Lymphoid Cells and CD4+ T Cells Potentiates Type 2 Immunity and Promotes Parasitic Helminth Expulsion
Authors: Christopher J. Oliphant, You Yi Hwang, Jennifer A. Walker, Maryam Salimi, See Heng Wong, James M. Brewer, Alexandros Englezakis, Jillian L. Barlow, Emily Hams, Seth Thomas Scanlon, Graham S. Ogg, Padraic G. Fallon, Andrew N. J. McKenzie - Immunity 2014 cited by 682
- PD-L1hi B cells are critical regulators of humoral immunity
Authors: Adnan R. Khan, Emily Hams, Achilleas Floudas, Tim Sparwasser, Casey T. Weaver, Padraic G. Fallon - Nature Communications 2015 cited by 370
- Tissue-Restricted Adaptive Type 2 Immunity Is Orchestrated by Expression of the Costimulatory Molecule OX40L on Group 2 Innate Lymphoid Cells
Authors: Timotheus Y.F. Halim, Batika M.J. Rana, Jennifer A. Walker, Bernhard Kerscher, Martin Knolle, Helen E. Jolin, Eva Serrão, Liora Haim-Vilmovsky, Sarah A. Teichmann, Hans‐Reimer Rodewald, Marina Botto, Timothy J. Vyse, Padraic G. Fallon, Zhi Li, David R. Withers, Andrew N. J. McKenzie - Immunity 2018 cited by 242
- Perinatal Activation of the Interleukin-33 Pathway Promotes Type 2 Immunity in the Developing Lung
Authors: Ismé M. de Kleer, Mirjam Kool, Marjolein J. W. de Bruijn, Monique Willart, Justine Van Moorleghem, Martijn J. Schuijs, Maud Plantinga, Rudi Beyaert, Emily Hams, Padraic G. Fallon, Hamida Hammad, Rudi W. Hendriks, Bart N. Lambrecht - Immunity 2016 cited by 342
- Group 2 innate lymphoid cells license dendritic cells to potentiate memory TH2 cell responses
Authors: Timotheus Y.F. Halim, You Yi Hwang, Seth Thomas Scanlon, Habib Zaghouani, Natalio Garbi, Padraic G. Fallon, Andrew N. J. McKenzie - Nature Immunology 2015 cited by 326
- Cell Survival and Cytokine Release after Inflammasome Activation Is Regulated by the Toll-IL-1R Protein SARM
Authors: Michael Carty, Jay Kearney, Katharine A. Shanahan, Emily Hams, Ryoichi Sugisawa, Dympna J. Connolly, Ciara Doran, Natalia Muñoz‐Wolf, Claudia Gürtler, Katherine A. Fitzgerald, Ed C. Lavelle, Padraic G. Fallon, Andrew Bowie - Immunity 2019 cited by 144
- When killers become thieves: Trogocytosed PD-1 inhibits NK cells in cancer
Authors: Mohamed S. Hasim, Marie Marotel, Jonathan J. Hodgins, Elisabetta Vulpis, Olivia Makinson, Sara Asif, Han‐Yu Shih, Amit Scheer, Olivia MacMillan, Felipe Gimenes Alonso, Kelly P. Burke, David P. Cook, Rui Li, Maria Teresa Petrucci, Angela Santoni, Padraic G. Fallon, Arlene H. Sharpe, Giuseppe Sciumè, André Veillette, Alessandra Zingoni, Douglas A. Gray, Arleigh McCurdy, Michele Ardolino - Science Advances 2022 cited by 101
- Dimethyl fumarate and 4-octyl itaconate are anticoagulants that suppress Tissue Factor in macrophages via inhibition of Type I Interferon
Authors: Tristram A.J. Ryan, Alexander Hooftman, Aisling M. Rehill, Matt D. Johansen, Eóin C. O’ Brien, Juliana E. Toller-Kawahisa, Mieszko M. Wilk, Emily A. Day, Hauke J. Weiss, Pourya Sarvari, Emilio G. Vozza, Fabian Schramm, Christian G. Peace, Alessia Zotta, Stefan Miemczyk, Christina Nalkurthi, Nicole G. Hansbro, Gavin McManus, Laura O’Doherty, Siobhán Gargan, Aideen Long, Jean Dunne, Clíona Ní Cheallaigh, Niall Conlon, Michael Carty, Padraic G. Fallon, Kingston H. G. Mills, Emma M. Creagh, James S. O’ Donnell, Paul J. Hertzog, Philip M. Hansbro, Rachel M. McLoughlin, Małgorzata Wygrecka, Roger J. S. Preston, Zbigniew Zasłona, Luke O'neill - Nature Communications 2023 cited by 64
- Skin microbiome before development of atopic dermatitis: Early colonization with commensal staphylococci at 2 months is associated with a lower risk of atopic dermatitis at 1 year
Authors: Elizabeth A. Kennedy, Jennifer Connolly, Jonathan O’B Hourihane, Padraic G. Fallon, W.H. Irwin McLean, Deirdre M. Murray, Jay‐Hyun Jo, Julia A. Segre, Heidi H. Kong, Alan D. Irvine - Journal of Allergy and Clinical Immunology 2016 cited by 345
- Aging impairs peritoneal but not bone marrow‐derived macrophage phagocytosis
Authors: Eimear Linehan, Yvonne Dombrowski, Rachel Snoddy, Padraic G. Fallon, Adrien Kissenpfennig, Denise Fitzgerald - Aging Cell 2014 cited by 175
- The PDGF-BB-SOX7 axis-modulated IL-33 in pericytes and stromal cells promotes metastasis through tumour-associated macrophages
Authors: Yunlong Yang, Patrik Andersson, Kayoko Hosaka, Yin Zhang, Renhai Cao, Hideki Iwamoto, Xiaojuan Yang, Masaki Nakamura, Jian Wang, Rujie Zhuang, Hiromasa Morikawa, Yuan Xue, Harald Braun, Rudi Beyaert, Nilesh J. Samani, Susumu Nakae, Emily Hams, Steen Dissing, Padraic G. Fallon, Robert Langer, Yihai Cao - Nature Communications 2016 cited by 188
- SREBP1-induced fatty acid synthesis depletes macrophages antioxidant defences to promote their alternative activation
Authors: Guillaume Bidault, Sam Virtue, Kasparas Petkevicius, Helen E. Jolin, Aurélien Dugourd, Anne-Claire Guénantin, Jennifer Leggat, Betania Mahler‐Araujo, Brian Lam, Marcella Ma, Martin Dale, Stefania Carobbio, Arthur Kaser, Padraic G. Fallon, Julio Sáez-Rodríguez, Andrew N. J. McKenzie, Antonio Vidal‐Puig - Nature Metabolism 2021 cited by 92
- IL-25 and type 2 innate lymphoid cells induce pulmonary fibrosis
Authors: Emily Hams, Michelle E. Armstrong, Jillian L. Barlow, Sean P. Saunders, Christian Schwartz, Gordon Cooke, Ruairi J. Fahy, Thomas B. Crotty, Nikhil Hirani, Robin J. Flynn, David Voehringer, Andrew N. J. McKenzie, Seamas C. Donnelly, Padraic G. Fallon - National Academy of Sciences, Proceedings of the National Academy of Sciences 2013 cited by 367
- The Alarmin Interleukin-33 Drives Protective Antiviral CD8 + T Cell Responses
Authors: Weldy V. Bonilla, Anja Fröhlich, Karin Senn, Sandra M. Kallert, Marylise Fernandez, Susan Johnson, Mario Kreutzfeldt, Ahmed N. Hegazy, Christina Schrick, Padraic G. Fallon, R Klemenz, Susumu Nakae, Heiko Adler, Doron Merkler, Max Löhning, Daniel D. Pinschewer - Science 2012 cited by 415
- Hypoxia-dependent regulation of inflammatory pathways in immune cells
Authors: Cormac T. Taylor, Glen Doherty, Padraic G. Fallon, Eoin P. Cummins - Journal of Clinical Investigation 2016 cited by 210
- Filaggrin loss-of-function mutations are associated with enhanced expression of IL-1 cytokines in the stratum corneum of patients with atopic dermatitis and in a murine model of filaggrin deficiency
Authors: Sanja Kežić, Gráinne M. O’Regan, René Lutter, Ivone Jakaša, Ellen S. Koster, Sean P. Saunders, Peter J. Caspers, P. M. J. H. Kemperman, Gerwin J. Puppels, Aileen Sandilands, Huijia Chen, Linda Campbell, Karin Kroboth, Rosemarie Watson, Padraic G. Fallon, W.H. Irwin McLean, Alan D. Irvine - Journal of Allergy and Clinical Immunology 2012 cited by 267
- Initiation of Antiviral B Cell Immunity Relies on Innate Signals from Spatially Positioned NKT Cells
Authors: Mauro Gaya, Patricia Barral, Marianne Burbage, Shweta Aggarwal, Beatriz Montaner, Andrew W. Navia, Malika Aïd, Carlson Tsui, Paula Maldonado, Usha Nair, Khader Ghneim, Padraic G. Fallon, Rafick‐Pierre Sékaly, Dan H. Barouch, Alex K. Shalek, Andreas Bruckbauer, Jessica Strid, Facundo D. Batista - Cell 2017 cited by 177
- IRAK4 inhibition dampens pathogenic processes driving inflammatory skin diseases
Authors: Stéphanie Lavazais, Manja Jargosch, Sonia Dupont, Frédéric Labéguère, Christel Menet, Catherine Jagerschmidt, Frenz Ohm, László Kupcsik, Isabelle Parent, C. Cottereaux, Florence Marsais, Line Oste, An Van de Water, Thierry Christophe, Steve De Vos, Padraic G. Fallon, Felix Lauffer, Philippe Clément-Lacroix, Kilian Eyerich, Reginald Brys - Science Translational Medicine 2023 cited by 40
