David H. Munn
Active 1987–2025
- Also published as
- David, H. Munn
- 131
- Papers
- 38,022
- Citations
- 97
- h-index
- 130
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Immunology and Microbiology30.4%
- Medicine30.3%
- Biochemistry, Genetics and Molecular Biology22.7%
- Neuroscience11.9%
- Engineering1.8%
- Agricultural and Biological Sciences0.8%
- Other2.1%
Topics
- Immune Cell Function and Interaction7.8%
- Cancer Immunotherapy and Biomarkers6.2%
- Immune cells in cancer5.6%
- Immunotherapy and Immune Responses5.3%
- Tryptophan and brain disorders5%
- Gut microbiota and health4.4%
- Other65.7%
Coauthors
- Andrew L. Mellor60
- Bruce R. Blazar28
- Phillip Chandler23
- Madhav Sharma16
- William J. Murphy15
- Babak Baban14
- Angela Panoskaltsis‐Mortari13
- Jonathan S. Serody10
- Theodore S. Johnson10
- Tracy L. McGaha10
- Huidong Shi9
- Lei Huang9
- Geoffrey R. Hill8
- Patricia A. Taylor8
- Paulo C. Rodrı́guez8
- Henrique Lemos7
- Ivan Maillard7
- Kelli P. A. MacDonald7
- Pandelakis A. Koni7
- Ryan Flynn7
- Brent H. Koehn6
- Corey Cutler6
- De-Yan Hou6
- Gang Zhou6
All papers
- Activation of Gpr109a, Receptor for Niacin and the Commensal Metabolite Butyrate, Suppresses Colonic Inflammation and Carcinogenesis
Authors: Nagendra Singh, Ashish Gurav, Sathish Sivaprakasam, Evan Brady, Ravi N. Padia, Huidong Shi, Muthusamy Thangaraju, Puttur D. Prasad, Santhakumar Manicassamy, David H. Munn, Jeffrey R. Lee, Stefan Offermanns, Vadivel Ganapathy - Immunity 2014 cited by 2,275
- IDO in the Tumor Microenvironment: Inflammation, Counter-Regulation, and Tolerance
Authors: David H. Munn, Andrew L. Mellor - Trends in Immunology 2016 cited by 1,024
- Ido expression by dendritic cells: tolerance and tryptophan catabolism
Authors: Andrew L. Mellor, David H. Munn - Nature reviews. Immunology 2004 cited by 2,315
- Indoleamine 2,3 dioxygenase and metabolic control of immune responses
Authors: David H. Munn, Andrew L. Mellor - Trends in Immunology 2012 cited by 1,007
- GCN2 Kinase in T Cells Mediates Proliferative Arrest and Anergy Induction in Response to Indoleamine 2,3-Dioxygenase
Authors: David H. Munn, Madhav Sharma, Babak Baban, Heather P. Harding, Yuhong Zhang, David Ron, Andrew L. Mellor - Immunity 2005 cited by 1,245
- The Unfolded Protein Response Mediator PERK Governs Myeloid Cell-Driven Immunosuppression in Tumors through Inhibition of STING Signaling
Authors: Eslam Mohamed, Rosa A. Sierra, Jimena Trillo-Tinoco, Yu Cao, Patrick Innamarato, Kyle K. Payne, Álvaro de Mingo Pulido, Jay K. Mandula, Shuzhong Zhang, Paul Thevenot, Subir Biswas, Sarah K. Abdalla, Tara Lee Costich, Kay Hänggi, Carmen M. Anadon, Elsa R. Flores, Eric B. Haura, Shikhar Mehrotra, Shari Pilon‐Thomas, Brian Ruffell, David H. Munn, Juan R. Cubillos‐Ruiz, José R. Conejo-García, Paulo C. Rodrı́guez - Immunity 2020 cited by 218
- Inhibition of T Cell Proliferation by Macrophage Tryptophan Catabolism
Authors: David H. Munn, Ebrahim Shafizadeh, John T. Attwood, I. E. Bondarev, Achal Pashine, Andrew L. Mellor - The Journal of Experimental Medicine 1999 cited by 1,617
- Ablation of the endoplasmic reticulum stress kinase PERK induces paraptosis and type I interferon to promote anti-tumor T cell responses
Authors: Jay K. Mandula, Shiun Chang, Eslam Mohamed, Rachel Jimenez, Rosa A. Sierra-Mondragon, Darwin Chang, Alyssa Obermayer, Carlos Moran Segura, Satyajit Das, Julio Angel Vázquez-Martínez, Karol Prieto, Ann Chen, Keiran S.M. Smalley, Brian J. Czerniecki, Peter Forsyth, Richard C. Koya, Brian Ruffell, Juan R. Cubillos‐Ruiz, David H. Munn, Timothy I. Shaw, José R. Conejo-García, Paulo C. Rodrı́guez - Cancer Cell 2022 cited by 155
- Tumor PD-L1 engages myeloid PD-1 to suppress type I interferon to impair cytotoxic T lymphocyte recruitment
Authors: John D. Klement, Priscilla S. Redd, Chunwan Lu, Alyssa D. Merting, Dakota B. Poschel, Dafeng Yang, Natasha M. Savage, Gang Zhou, David H. Munn, Padraic G. Fallon, Kebin Liu - Cancer Cell 2023 cited by 119
- Coexpression of Tim-3 and PD-1 identifies a CD8+ T-cell exhaustion phenotype in mice with disseminated acute myelogenous leukemia
Authors: Qing Zhou, Meghan E. Munger, Rachelle G. Veenstra, Brenda J. Weigel, Mitsuomi Hirashima, David H. Munn, William J. Murphy, Miyuki Azuma, Ana C. Anderson, Vijay K. Kuchroo, Bruce R. Blazar - Blood 2011 cited by 679
- Immune suppressive mechanisms in the tumor microenvironment
Authors: David H. Munn, Vincenzo Bronte - Current Opinion in Immunology 2015 cited by 524
- STING Promotes the Growth of Tumors Characterized by Low Antigenicity via IDO Activation
Authors: Henrique Lemos, Eslam Mohamed, Lei Huang, Rong Ou, Gabriela Pacholczyk, Ali S. Arbab, David H. Munn, Andrew L. Mellor - Cancer Research 2016 cited by 325
- Prevention of Allogeneic Fetal Rejection by Tryptophan Catabolism
Authors: David H. Munn, Min Zhou, John T. Attwood, I. E. Bondarev, Simon J. Conway, Brendan Marshall, Corrie C. Brown, Andrew L. Mellor - Science 1998 cited by 2,592
- Tumor-Expressed IDO Recruits and Activates MDSCs in a Treg-Dependent Manner
Authors: Rikke Holmgaard, Dmitriy Zamarin, Yanyun Li, Billel Gasmi, David H. Munn, James P. Allison, Taha Merghoub, Jedd D. Wolchok - Cell Reports 2015 cited by 488
- Apoptotic cell–induced AhR activity is required for immunological tolerance and suppression of systemic lupus erythematosus in mice and humans
Authors: Rahul Shinde, Kebria Hezaveh, Marie Jo Halaby, Andreas Kloetgen, Ankur Chakravarthy, Tiago da Silva Medina, Reema Deol, Kieran Manion, Yuriy Baglaenko, Maria Eldh, Sara Lamorte, Drew Wallace, Sathi Babu Chodisetti, Buvana Ravishankar, Haiyun Liu, Kapil Chaudhary, David H. Munn, Aristotelis Tsirigos, Michael P. Madaio, Susanne Gabrielsson, Zahi Touma, Joan Wither, Daniel D. De Carvalho, Tracy L. McGaha - Nature Immunology 2018 cited by 201
- Indoleamine 2,3-dioxygenase is a critical resistance mechanism in antitumor T cell immunotherapy targeting CTLA-4
Authors: Rikke Holmgaard, Dmitriy Zamarin, David H. Munn, Jedd D. Wolchok, James P. Allison - The Journal of Experimental Medicine 2013 cited by 636
- GCN2 drives macrophage and MDSC function and immunosuppression in the tumor microenvironment
Authors: Marie Jo Halaby, Kebria Hezaveh, Sara Lamorte, M. Teresa Ciudad, Andreas Kloetgen, Bethany MacLeod, Mengdi Guo, Ankur Chakravarthy, Tiago da Silva Medina, Stefano Ugel, Aristotelis Tsirigos, Vincenzo Bronte, David H. Munn, Trevor J. Pugh, Daniel D. De Carvalho, Marcus O. Butler, Pamela S. Ohashi, David G. Brooks, Tracy L. McGaha - Science Immunology 2019 cited by 186
- ER stress-induced mediator C/EBP homologous protein thwarts effector T cell activity in tumors through T-bet repression
Authors: Yu Cao, Jimena Trillo-Tinoco, Rosa A. Sierra, Carmen M. Anadon, Wenjie Dai, Eslam Mohamed, Ling Cen, Tara Lee Costich, Anthony M. Magliocco, Douglas C. Marchion, Richard Klar, Sven Michel, Frank Jaschinski, Richard R. Reich, Shikhar Mehrotra, Juan R. Cubillos‐Ruiz, David H. Munn, José R. Conejo-García, Paulo C. Rodrı́guez - Nature Communications 2019 cited by 158
- CD73 on cancer-associated fibroblasts enhanced by the A2B-mediated feedforward circuit enforces an immune checkpoint
Authors: Miao Yu, Gang Guo, Lei Huang, Libin Deng, Chang-Sheng Chang, Bhagelu R. Achyut, Madison Canning, Ningchun Xu, Ali S. Arbab, Roni J. Bollag, Paulo C. Rodrı́guez, Andrew L. Mellor, Huidong Shi, David H. Munn, Yan Cui - Nature Communications 2020 cited by 185
- Advanced Age Increases Immunosuppression in the Brain and Decreases Immunotherapeutic Efficacy in Subjects with Glioblastoma
Authors: Erik Ladomersky, Lijie Zhai, Kristen L. Lauing, April Bell, Jiahui Xu, Masha Kocherginsky, Bin Zhang, Jennifer D. Wu, Joseph R. Podojil, Leonidas C. Platanias, Aaron Mochizuki, Robert M. Prins, Priya Kumthekar, Jeffrey J. Raizer, Karan Dixit, Rimas V. Lukas, Craig Horbinski, Wei Min, Changyou Zhou, Graham Pawelec, Judith Campisi, Ursula Grohmann, George C. Prendergast, David H. Munn, Derek A. Wainwright - Clinical Cancer Research 2020 cited by 110
- The Indoleamine 2,3-Dioxygenase Pathway Is Essential for Human Plasmacytoid Dendritic Cell-Induced Adaptive T Regulatory Cell Generation
Authors: Wei Chen, Xueqing Liang, Amanda J. Peterson, David H. Munn, Bruce R. Blazar - The Journal of Immunology 2008 cited by 454
- Indoleamine 2,3-dioxygenase and tumor-induced tolerance
Authors: David H. Munn, Andrew L. Mellor - Journal of Clinical Investigation 2007 cited by 1,064
- IDO inhibits a tryptophan sufficiency signal that stimulates mTOR: A novel IDO effector pathway targeted by D-1-methyl-tryptophan
Authors: Richard Metz, Sonja Rust, James B. DuHadaway, Mario R. Mautino, David H. Munn, Nicholas N. Vahanian, Charles J. Link, George C. Prendergast - OncoImmunology 2012 cited by 377
- Butyrate suppresses colonic inflammation through HDAC1-dependent Fas upregulation and Fas-mediated apoptosis of T cells
Authors: Mary Ann Zimmerman, Nagendra Singh, Pamela M. Martin, Muthusamy Thangaraju, Vadivel Ganapathy, Jennifer L. Waller, Huidong Shi, Keith D. Robertson, David H. Munn, Kebin Liu - American Journal of Physiology-Gastrointestinal and Liver Physiology 2012 cited by 277
