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Heather P. Harding

Active 1991–2024

94
Papers
53,573
Citations
84
h-index
93
i10-index

Citations

Citations per year for Heather P. Harding1983: 1 citations1990: 2 citations1992: 13 citations1993: 14 citations1994: 11 citations1995: 25 citations1996: 44 citations1997: 64 citations1998: 54 citations1999: 81 citations2000: 165 citations2001: 184 citations2002: 327 citations2003: 377 citations2004: 538 citations2005: 570 citations2006: 702 citations2007: 799 citations2008: 686 citations2009: 724 citations2010: 738 citations2011: 714 citations2012: 906 citations2013: 906 citations2014: 957 citations2015: 818 citations2016: 745 citations2017: 745 citations2018: 683 citations2019: 1,845 citations2020: 2,035 citations2021: 1,894 citations2022: 1,433 citations2023: 915 citations2024: 1,508 citations2025: 621 citations2026: 13 citations1984–1989: no citations, so these years are not shown1991: no citations, so this year is not shown

Citation sources

Countries

World map of the countries and regions citing this authorUnited States: 5,526 citing papers, 31.3% of this breakdownChina: 1,993 citing papers, 11.3% of this breakdownUnited Kingdom: 1,060 citing papers, 6% of this breakdownGermany: 902 citing papers, 5.1% of this breakdownJapan: 797 citing papers, 4.5% of this breakdownCanada: 697 citing papers, 3.9% of this breakdownFrance: 682 citing papers, 3.9% of this breakdownItaly: 557 citing papers, 3.1% of this breakdownAustralia: 407 citing papers, 2.3% of this breakdownSouth Korea: 390 citing papers, 2.2% of this breakdownSwitzerland: 335 citing papers, 1.9% of this breakdownSpain: 326 citing papers, 1.8% of this breakdown
0%31.3%Other 22.7%

Institutions

Fields

  • Biochemistry, Genetics and Molecular Biology59.6%
  • Medicine26.6%
  • Neuroscience5.7%
  • Immunology and Microbiology4.4%
  • Agricultural and Biological Sciences1%
  • Nursing0.7%
  • Other2%

Topics

  • Endoplasmic Reticulum Stress and Disease13.8%
  • Autophagy in Disease and Therapy6%
  • RNA regulation and disease3.1%
  • Pancreatic function and diabetes2.8%
  • RNA Research and Splicing2%
  • Mitochondrial Function and Pathology1.9%
  • Other70.4%

Coauthors

All papers

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  1. An Integrated Stress Response Regulates Amino Acid Metabolism and Resistance to Oxidative Stress

    Authors: Heather P. Harding, Yuhong Zhang, Huiquing Zeng, Isabel Novoa, Phoebe D. Lu, Marcella A. Calfon, Navid Sadri, Chi Young Yun, Brian Popko, Richard S. Paules, David F. Stojdl, John C. Bell, Thore Hettmann, Jeffrey M. Leiden, David Ron - Molecular Cell 2003 cited by 3,314

  2. Regulated Translation Initiation Controls Stress-Induced Gene Expression in Mammalian Cells

    Authors: Heather P. Harding, Isabel Novoa, Yuhong Zhang, Huiqing Zeng, Ronald C. Wek, Matthieu Schapira, David Ron - Molecular Cell 2000 cited by 3,241

  3. Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase

    Authors: Heather P. Harding, Yuhong Zhang, David Ron - Nature 1999 cited by 3,347

  4. Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response

    Authors: Anne Bertolotti, Yuhong Zhang, Linda M. Hendershot, Heather P. Harding, David Ron - Nature Cell Biology 2000 cited by 2,860

  5. IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA

    Authors: Marcella A. Calfon, Huiqing Zeng, Fumihiko Urano, Jeffery H. Till, Stevan R. Hubbard, Heather P. Harding, Scott G. Clark, David Ron - Nature 2002 cited by 2,889

  6. Coupling of Stress in the ER to Activation of JNK Protein Kinases by Transmembrane Protein Kinase IRE1

    Authors: Fumihiko Urano, Xiao-Zhong Wang, Anne Bertolotti, Yuhong Zhang, Peter Chung, Heather P. Harding, David Ron - Science 2000 cited by 2,992

  7. GDF15 Provides an Endocrine Signal of Nutritional Stress in Mice and Humans

    Authors: Satish Patel, Anna Álvarez-Guaita, Audrey Melvin, Debra Rimmington, Alessia Dattilo, Emily L. Miedzybrodzka, Irène Cimino, Anne‐Catherine Maurin, Geoffrey Roberts, Claire L. Meek, Sam Virtue, Lauren M. Sparks, Stephanie A. Parsons, Leanne M. Redman, George A. Bray, Alice P. Liou, Rachel Woods, Siôn Parry, Per Bendix Jeppesen, Anders J. Kolnes, Heather P. Harding, David Ron, Antonio Vidal‐Puig, Frank Reimann, Fiona M. Gribble, Carl J. Hulston, I. Sadaf Farooqi, Pierre Fafournoux, Steven R. Smith, Jorgen Jensen, Danna M. Breen, Zhidan Wu, Bei B. Zhang, Anthony P. Coll, David B. Savage, Stephen O’Rahilly - Cell Metabolism 2019 cited by 499

  8. GDF15 mediates the effects of metformin on body weight and energy balance

    Authors: Anthony P. Coll, Michael Chen, Pranali Taskar, Debra Rimmington, Satish Patel, John A. Tadross, Irène Cimino, Ming Yang, Paul Welsh, Sam Virtue, Deborah A. Goldspink, Emily L. Miedzybrodzka, Adam R. Konopka, Raul Ruiz Esponda, Jeffrey Huang, Y. C. Loraine Tung, Sergio Rodríguez‐Cuenca, Rute A. Tomaz, Heather P. Harding, Audrey Melvin, Giles S.H. Yeo, David Preiss, Antonio Vidal‐Puig, Ludovic Vallier, K. Sreekumaran Nair, Nicholas J. Wareham, David Ron, Fiona M. Gribble, Frank Reimann, Naveed Sattar, David B. Savage, Bernard B. Allan, Stephen O’Rahilly - Nature 2019 cited by 570

  9. CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulum

    Authors: Stefan J. Marciniak, Chi Young Yun, Seiichi Oyadomari, Isabel Novoa, Yuhong Zhang, Rivka Jungreis, Kazuhiro Nagata, Heather P. Harding, David Ron - Genes & Development 2004 cited by 1,989

  10. GCN2 Kinase in T Cells Mediates Proliferative Arrest and Anergy Induction in Response to Indoleamine 2,3-Dioxygenase

    Authors: David H. Munn, Madhav Sharma, Babak Baban, Heather P. Harding, Yuhong Zhang, David Ron, Andrew L. Mellor - Immunity 2005 cited by 1,245

  11. Perk Is Essential for Translational Regulation and Cell Survival during the Unfolded Protein Response

    Authors: Heather P. Harding, Yuhong Zhang, Anne Bertolotti, Huiqing Zeng, David Ron - Molecular Cell 2000 cited by 2,008

  12. Feedback Inhibition of the Unfolded Protein Response by GADD34-Mediated Dephosphorylation of eIF2α

    Authors: Isabel Novoa, Huiqing Zeng, Heather P. Harding, David Ron - The Journal of Cell Biology 2001 cited by 1,373

  13. Predicting the mutations generated by repair of Cas9-induced double-strand breaks

    Authors: Felicity Allen, Luca Crepaldi, Clara Alsinet, Alexander Strong, Vitalii Kleshchevnikov, Pietro De Angeli, Petra Páleníková, Anton Khodak, Vladimir Yu Kiselev, Michael Kosicki, Andrew Bassett, Heather P. Harding, Yaron Galanty, Francisco Muñoz‐Martínez, Emmanouil Metzakopian, Stephen P. Jackson, Leopold Parts - Nature Biotechnology 2018 cited by 527

  14. Translation reinitiation at alternative open reading frames regulates gene expression in an integrated stress response

    Authors: Phoebe D. Lu, Heather P. Harding, David Ron - The Journal of Cell Biology 2004 cited by 993

  15. A Selective Inhibitor of eIF2α Dephosphorylation Protects Cells from ER Stress

    Authors: Michael Boyce, Kevin F. Bryant, Céline Jousse, Kai Long, Heather P. Harding, Donalyn Scheuner, Randal J. Kaufman, Dawei Ma, Donald M. Coen, David Ron, Junying Yuan - Science 2005 cited by 1,412

  16. Role of ERO1-α–mediated stimulation of inositol 1,4,5-triphosphate receptor activity in endoplasmic reticulum stress–induced apoptosis

    Authors: Gang Li, Marco Mongillo, King‐Tung Chin, Heather P. Harding, David Ron, Andrew R. Marks, Ira Tabas - The Journal of Cell Biology 2009 cited by 583

  17. Somatic CALR Mutations in Myeloproliferative Neoplasms with Nonmutated JAK2

    Authors: Jyoti Nangalia, Charles Massie, E. Joanna Baxter, Francesca Nice, Gunes Gundem, David C. Wedge, Edward Avezov, J. Li, Karoline Kollmann, David G. Kent, Aziz Aziz, Anna L. Godfrey, Jonathan Hinton, Iñigo Martincorena, Peter Van Loo, Amy V. Jones, Paola Guglielmelli, Patrick Tarpey, Heather P. Harding, John D. Fitzpatrick, Calum T Goudie, Christina A. Ortmann, Stephen J. Loughran, Keiran Raine, Daniel Jones, Adam P. Butler, Jon W. Teague, Sarah O’Meara, Stuart McLaren, Michele Leonardo Bianchi, Yvonne Silber, D. Dimitropoulou, David Bloxham, Laura Mudie, Mark Maddison, Ben Robinson, Clodagh Keohane, Cathy MacLean, Kate Hill, Kim Orchard, Sheral Raina Tauro, Ming‐Qing Du, Mel Greaves, David Bowen, Brian J.P. Huntly, Claire Harrison, Nicholas C.P. Cross, David Ron, Alessandro M. Vannucchi, Elli Papaemmanuil, Peter J. Campbell, Anthony R. Green - New England Journal of Medicine 2013 cited by 1,737

  18. The ribosomal P-stalk couples amino acid starvation to GCN2 activation in mammalian cells

    Authors: Heather P. Harding, A. Ordóñez, Felicity Allen, Leopold Parts, Alison J. Inglis, Roger Williams, David Ron - eLife 2019 cited by 178

  19. Compartment-specific perturbation of protein handling activates genes encoding mitochondrial chaperones

    Authors: Takunari Yoneda, Cristina Benedetti, Fumihiko Urano, Scott G. Clark, Heather P. Harding, David Ron - Journal of Cell Science 2004 cited by 670

  20. The molecular basis for selective inhibition of unconventional mRNA splicing by an IRE1-binding small molecule

    Authors: Benedict C. S. Cross, Peter J. Bond, Paweł Sadowski, Babal K. Jha, Jaroslav Žák, Jonathan M. Goodman, Robert H. Silverman, Thomas A. Neubert, Ian R. Baxendale, David Ron, Heather P. Harding - National Academy of Sciences, Proceedings of the National Academy of Sciences 2012 cited by 594

  21. Diabetes Mellitus and Exocrine Pancreatic Dysfunction in Perk−/− Mice Reveals a Role for Translational Control in Secretory Cell Survival

    Authors: Heather P. Harding, Huiqing Zeng, Yuhong Zhang, Rivka Jungries, Peter Chung, Heidi Plesken, David D. Sabatini, David Ron - Molecular Cell 2001 cited by 1,213

  22. Partial restoration of protein synthesis rates by the small molecule ISRIB prevents neurodegeneration without pancreatic toxicity

    Authors: M.S. Halliday, Helois Radford, Yusuke Sekine, Julie A. Moreno, Nicholas Verity, John Le Quesne, Catharine A. Ortori, David A. Barrett, Christophe Fromont, Peter M. Fischer, Heather P. Harding, David Ron, Giovanna R. Mallucci - Cell Death and Disease 2015 cited by 384

  23. A J-Protein Co-chaperone Recruits BiP to Monomerize IRE1 and Repress the Unfolded Protein Response

    Authors: Niko Amin-Wetzel, Reuben A. Saunders, Maarten J. Kamphuis, Cláudia Rato, Steffen Preißler, Heather P. Harding, David Ron - Cell 2017 cited by 261

  24. Targeting the unfolded protein response in disease

    Authors: Claudio Hetz, Éric Chevet, Heather P. Harding - Nature Reviews Drug Discovery 2013 cited by 902