David E. James
Active 1969–2025
- 228
- Papers
- 36,829
- Citations
- 112
- h-index
- 219
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Biochemistry, Genetics and Molecular Biology47.1%
- Medicine35.4%
- Earth and Planetary Sciences4.6%
- Neuroscience2.9%
- Immunology and Microbiology2.2%
- Chemistry1.9%
- Other5.9%
Topics
- Metabolism, Diabetes, and Cancer5.8%
- Adipose Tissue and Metabolism5.7%
- Pancreatic function and diabetes3.2%
- Cellular transport and secretion2.9%
- Adipokines, Inflammation, and Metabolic Diseases2.3%
- Diet and metabolism studies1.7%
- Other78.4%
Coauthors
- Daniel J. Fazakerley35
- Sean J. Humphrey30
- Jacqueline Stöckli27
- Benjamin L. Parker26
- James G. Burchfield24
- Kristen C. Cooke23
- James R. Krycer18
- Gregory J. Cooney17
- Pengyi Yang17
- Alexis Díaz‐Vegas15
- Edward W. Kraegen14
- Elise J. Needham14
- Kyle L. Hoehn13
- Donald J. Chisholm12
- Guang Yang12
- Søren Madsen12
- Mark Larance11
- Nigel Turner11
- Sally Martin11
- Erik A. Richter10
- Dougall M. Norris9
- Robert C. Piper9
- Samantha Hocking9
- Georg Ramm8
All papers
- The aetiology and molecular landscape of insulin resistance
Authors: David E. James, Jacqueline Stöckli, Morris J. Birnbaum - Nature Reviews Molecular Cell Biology 2021 cited by 666
- Extracellular Vesicles Provide a Means for Tissue Crosstalk during Exercise
Authors: Martin Whitham, Benjamin L. Parker, Martin Friedrichsen, Janne R. Hingst, Marit Hjorth, William E. Hughes, Casey L. Egan, Lena Cron, Kevin I. Watt, Rhiannon P. Kuchel, Navind Jayasooriah, Emma Estévez, Tim Petzold, Catherine M. Suter, Paul Gregorevic, Bente Kiens, Erik A. Richter, David E. James, Jørgen F. P. Wojtaszewski, Mark A. Febbraio - Cell Metabolism 2018 cited by 657
- Interleukin-6 Increases Insulin-Stimulated Glucose Disposal in Humans and Glucose Uptake and Fatty Acid Oxidation In Vitro via AMP-Activated Protein Kinase
Authors: Andrew L. Carey, Gregory R. Steinberg, S. Lance Macaulay, Walter G. Thomas, Anna G. Holmes, Georg Ramm, Oja Prelovsek, Cordula Hohnen-Behrens, Matthew J. Watt, David E. James, Bruce E. Kemp, Bente Klarlund Pedersen, Mark A. Febbraio - Diabetes 2006 cited by 885
- Illuminating the dark phosphoproteome
Authors: Elise J. Needham, Benjamin L. Parker, Timur Burykin, David E. James, Sean J. Humphrey - Science Signaling 2019 cited by 361
- Protein Phosphorylation: A Major Switch Mechanism for Metabolic Regulation
Authors: Sean J. Humphrey, David E. James, Matthias Mann - Trends in Endocrinology and Metabolism 2015 cited by 565
- Vascular cells improve functionality of human cardiac organoids
Authors: Holly K. Voges, Simon R. Foster, Liam Reynolds, Benjamin L. Parker, Lynn Devilée, Gregory A. Quaife-Ryan, Patrick R.J. Fortuna, Ellen Mathieson, Rebecca Fitzsimmons, Mary Lor, Christopher Batho, Janice Reid, Mark Pocock, Clayton E. Friedman, Dalia Mizikovsky, Mathias François, Nathan J. Palpant, Elise J. Needham, Marina Díaz Peralta, Gonzalo del Monte‐Nieto, Lynelle K. Jones, Ian Smyth, Neda R. Mehdiabadi, Francesca Bolk, Vaibhao Janbandhu, Ernestene Yao, Richard P. Harvey, James J.H. Chong, David A. Elliott, Edouard G. Stanley, Sophie Wiszniak, Quenten Schwarz, David E. James, Richard J. Mills, Enzo R. Porrello, James E. Hudson - Cell Reports 2023 cited by 127
- High-throughput and high-sensitivity phosphoproteomics with the EasyPhos platform
Authors: Sean J. Humphrey, Özge Karayel, David E. James, Matthias Mann - Nature Protocols 2018 cited by 382
- Functional screening in human cardiac organoids reveals a metabolic mechanism for cardiomyocyte cell cycle arrest
Authors: Richard J. Mills, Drew M. Titmarsh, Xaver Koenig, Benjamin L. Parker, James G. Ryall, Gregory A. Quaife-Ryan, Holly K. Voges, Mark P. Hodson, Charles Ferguson, Lauren Drowley, Alleyn T. Plowright, Elise J. Needham, Qing-Dong Wang, Paul Gregorevic, Mei Xin, Walter G. Thomas, Robert G. Parton, Lars K. Nielsen, Bradley S. Launikonis, David E. James, David A. Elliott, Enzo R. Porrello, James E. Hudson - National Academy of Sciences, Proceedings of the National Academy of Sciences 2017 cited by 465
- Global Phosphoproteomic Analysis of Human Skeletal Muscle Reveals a Network of Exercise-Regulated Kinases and AMPK Substrates
Authors: Nolan J. Hoffman, Benjamin L. Parker, Rima Chaudhuri, Kelsey H. Fisher‐Wellman, Maximilian Kleinert, Sean J. Humphrey, Pengyi Yang, Mira Holliday, Sophie Trefely, Daniel J. Fazakerley, Jacqueline Stöckli, James G. Burchfield, Thomas E. Jensen, Raja Jothi, Bente Kiens, Jørgen F. P. Wojtaszewski, Erik A. Richter, David E. James - Cell Metabolism 2015 cited by 439
- BET inhibition blocks inflammation-induced cardiac dysfunction and SARS-CoV-2 infection
Authors: Richard J. Mills, Sean J. Humphrey, Patrick R.J. Fortuna, Mary Lor, Simon R. Foster, Gregory A. Quaife-Ryan, Rebecca L. Johnston, Troy Dumenil, Cameron Bishop, Rajeev Rudraraju, Daniel J. Rawle, Thuy T. T. Le, Wei Zhao, Leo Lee, Charley Mackenzie-Kludas, Neda R. Mehdiabadi, Christopher Halliday, Dean Gilham, Li Fu, Stephen J. Nicholls, Jan O. Johansson, Michael Sweeney, Norman C.W. Wong, Ewelina Kulikowski, Kamil A. Sokolowski, Brian Wan-Chi Tse, Lynn Devilée, Holly K. Voges, Liam Reynolds, Sophie Krumeich, Ellen Mathieson, Dad Abu-Bonsrah, Kathy Karavendzas, Brendan Griffen, Drew M. Titmarsh, David A. Elliott, James McMahon, Andreas Suhrbier, Kanta Subbarao, Enzo R. Porrello, Mark J. Smyth, Christian Engwerda, Kelli P. A. MacDonald, Tobias Bald, David E. James, James E. Hudson - Cell 2021 cited by 236
- Drug Screening in Human PSC-Cardiac Organoids Identifies Pro-proliferative Compounds Acting via the Mevalonate Pathway
Authors: Richard J. Mills, Benjamin L. Parker, Gregory A. Quaife-Ryan, Holly K. Voges, Elise J. Needham, Aurélie Bornot, Mei Ding, Henrik Andersson, Magnus Polla, David A. Elliott, Lauren Drowley, Maryam Clausen, Alleyn T. Plowright, Ian P. Barrett, Qing‐Dong Wang, David E. James, Enzo R. Porrello, James E. Hudson - Cell stem cell 2019 cited by 302
- Muscle and adipose tissue insulin resistance: malady without mechanism?
Authors: Daniel J. Fazakerley, James R. Krycer, Alison L. Kearney, Samantha Hocking, David E. James - Journal of Lipid Research 2018 cited by 182
- Global redox proteome and phosphoproteome analysis reveals redox switch in Akt
Authors: Zhiduan Su, James G. Burchfield, Pengyi Yang, Sean J. Humphrey, Guang Yang, Deanne Francis, Sabina Yasmin, Sung‐Young Shin, Dougall M. Norris, Alison L. Kearney, Miro A. Astore, Jonathan Scavuzzo, Kelsey H. Fisher‐Wellman, Qiao‐Ping Wang, Benjamin L. Parker, G. Gregory Neely, Fatemeh Vafaee, Joyce Chiu, Reichelle X. Yeo, Philip J. Hogg, Daniel J. Fazakerley, Lan K. Nguyen, Serdar Kuyucak, David E. James - Nature Communications 2019 cited by 149
- Personalized phosphoproteomics identifies functional signaling
Authors: Elise J. Needham, Janne R. Hingst, Benjamin L. Parker, Kaitlin R. Morrison, Guang Yang, Johan Onslev, Jonas M. Kristensen, Kurt Højlund, Naomi X.Y. Ling, Jonathan S. Oakhill, Erik A. Richter, Bente Kiens, Janni Petersen, Christian Pehmøller, David E. James, Jørgen F. P. Wojtaszewski, Sean J. Humphrey - Nature Biotechnology 2021 cited by 112
- Akt phosphorylates insulin receptor substrate to limit PI3K-mediated PIP3 synthesis
Authors: Alison L. Kearney, Dougall M. Norris, Milad Ghomlaghi, Martin Kin Lok Wong, Sean J. Humphrey, Luke Carroll, Guang Yang, Kristen C. Cooke, Pengyi Yang, Thomas A. Geddes, Sung‐Young Shin, Daniel J. Fazakerley, Lan K. Nguyen, David E. James, James G. Burchfield - eLife 2021 cited by 85
- Dynamic Adipocyte Phosphoproteome Reveals that Akt Directly Regulates mTORC2
Authors: Sean J. Humphrey, Guang Yang, Pengyi Yang, Daniel J. Fazakerley, Jacqueline Stöckli, Jean Yang, David E. James - Cell Metabolism 2013 cited by 428
- Thirty sweet years of GLUT4
Authors: Amira Klip, Timothy E. McGraw, David E. James - Journal of Biological Chemistry 2019 cited by 359
- PhosR enables processing and functional analysis of phosphoproteomic data
Authors: Hani Jieun Kim, Tai-Yun Kim, Nolan J. Hoffman, Di Xiao, David E. James, Sean J. Humphrey, Pengyi Yang - Cell Reports 2021 cited by 125
- Mitochondrial CoQ deficiency is a common driver of mitochondrial oxidants and insulin resistance
Authors: Daniel J. Fazakerley, Rima Chaudhuri, Pengyi Yang, Ghassan J. Maghzal, Kristen C. Thomas, James R. Krycer, Sean J. Humphrey, Benjamin L. Parker, Kelsey H. Fisher‐Wellman, Christopher C. Meoli, Nolan J. Hoffman, Ciana Diskin, James G. Burchfield, Mark J. Cowley, Warren Kaplan, Zora Modrušan, Ganesh Kolumam, Jean Yang, Daniel L. Chen, Dorit Samocha‐Bonet, Jerry R. Greenfield, Kyle L. Hoehn, Roland Stocker, David E. James - eLife 2018 cited by 162
- Regulated transport of the glucose transporter GLUT4
Authors: Nia J. Bryant, Roland Govers, David E. James - Nature Reviews Molecular Cell Biology 2002 cited by 1,185
- A Positive Feedback Loop between Akt and mTORC2 via SIN1 Phosphorylation
Authors: Guang Yang, Danielle Murashige, Sean J. Humphrey, David E. James - Cell Reports 2015 cited by 298
- Defining the Nutritional and Metabolic Context of FGF21 Using the Geometric Framework
Authors: Samantha M. Solon‐Biet, Victoria C. Cogger, Tamara Pulpitel, Marika Heblinski, Devin Wahl, Aisling C. McMahon, Alessandra Warren, Jessica Durrant-Whyte, Kirsty A. Walters, James R. Krycer, Fleur Ponton, Rahul Gokarn, Jibran A. Wali, Kari Ruohonen, Arthur D. Conigrave, David E. James, David Raubenheimer, Christopher D. Morrison, David G. Le Couteur, Stephen J. Simpson - Cell Metabolism 2016 cited by 211
- Regulator of Fatty Acid Metabolism, Acetyl Coenzyme A Carboxylase 1, Controls T Cell Immunity
Authors: JangEun Lee, Matthew C. Walsh, Kyle L. Hoehn, David E. James, E. John Wherry, Yongwon Choi - The Journal of Immunology 2014 cited by 208
- A novel Rab10-EHBP1-EHD2 complex essential for the autophagic engulfment of lipid droplets
Authors: Zhipeng Li, Ryan J. Schulze, Shaun G. Weller, Eugene W. Krueger, Micah B. Schott, Xiaodong Zhang, Carol A. Casey, Jun Liu, Jacqueline Stöckli, David E. James, Mark A. McNiven - Science Advances 2016 cited by 180
