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E. John Wherry

Active 1997–2026

270
Papers
105,461
Citations
142
h-index
264
i10-index

Citations

Citations per year for E. John Wherry1945: 1 citations1989: 1 citations1990: 6 citations1991: 1 citations1993: 1 citations1994: 1 citations1995: 2 citations1997: 3 citations1998: 4 citations1999: 12 citations2000: 2 citations2001: 5 citations2002: 21 citations2003: 112 citations2004: 252 citations2005: 279 citations2006: 377 citations2007: 458 citations2008: 522 citations2009: 638 citations2010: 751 citations2011: 671 citations2012: 766 citations2013: 826 citations2014: 814 citations2015: 1,010 citations2016: 1,230 citations2017: 1,331 citations2018: 1,594 citations2019: 4,223 citations2020: 5,444 citations2021: 7,006 citations2022: 5,655 citations2023: 4,440 citations2024: 5,998 citations2025: 3,383 citations2026: 181 citations1946–1988: no citations, so these years are not shown1992: no citations, so this year is not shown1996: no citations, so this year is not shown

Citation sources

Countries

World map of the countries and regions citing this authorUnited States: 13,186 citing papers, 31.1% of this breakdownChina: 6,179 citing papers, 14.6% of this breakdownUnited Kingdom: 2,395 citing papers, 5.6% of this breakdownGermany: 2,248 citing papers, 5.3% of this breakdownFrance: 1,480 citing papers, 3.5% of this breakdownItaly: 1,416 citing papers, 3.3% of this breakdownCanada: 1,297 citing papers, 3.1% of this breakdownAustralia: 1,264 citing papers, 3% of this breakdownJapan: 1,160 citing papers, 2.7% of this breakdownNetherlands: 1,031 citing papers, 2.4% of this breakdownSwitzerland: 1,007 citing papers, 2.4% of this breakdownSpain: 796 citing papers, 1.9% of this breakdown
0%31.1%Other 21.1%

Institutions

Fields

  • Medicine50.8%
  • Immunology and Microbiology28.5%
  • Biochemistry, Genetics and Molecular Biology17%
  • Engineering1.2%
  • Neuroscience1%
  • Agricultural and Biological Sciences0.4%
  • Other1.1%

Topics

  • Immune Cell Function and Interaction10.1%
  • Cancer Immunotherapy and Biomarkers8%
  • Immunotherapy and Immune Responses7%
  • CAR-T cell therapy research5.7%
  • T-cell and B-cell Immunology5.5%
  • SARS-CoV-2 and COVID-19 Research2.9%
  • Other60.8%

Coauthors

All papers

Open in search
  1. Molecular and cellular insights into T cell exhaustion

    Authors: E. John Wherry, Makoto Kurachi - Nature reviews. Immunology 2015 cited by 4,522

  2. Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response

    Authors: Gang Chen, Alexander C. Huang, Wei Zhang, Gao Zhang, Min Wu, Wei Xu, Zi‐Li Yu, Jiegang Yang, Beike Wang, Honghong Sun, Hou-Fu Xia, Qi‐Wen Man, Wenqun Zhong, Leonardo F. Antelo, Bin Wu, Xuepeng Xiong, Xiaoming Liu, Lei Guan, Ting Li, Shujing Liu, Ruifeng Yang, Youtao Lu, Liyun Dong, Suzanne McGettigan, Rajasekharan Somasundaram, Ravi Radhakrishnan, Gordon B. Mills, Yiling Lu, Junhyong Kim, Youhai H. Chen, Haidong Dong, Yi‐Fang Zhao, Giorgos C. Karakousis, Tara C. Mitchell, Lynn M. Schuchter, Meenhard Herlyn, E. John Wherry, Xiaowei Xu, Wei Guo - Nature 2018 cited by 2,837

  3. CD8 T Cell Exhaustion During Chronic Viral Infection and Cancer

    Authors: Laura M. McLane, Mohamed S. Abdel-Hakeem, E. John Wherry - Annual Review of Immunology 2019 cited by 1,997

  4. T cell exhaustion

    Authors: E. John Wherry - Nature Immunology 2011 cited by 4,014

  5. Determinants of response and resistance to CD19 chimeric antigen receptor (CAR) T cell therapy of chronic lymphocytic leukemia

    Authors: Joseph A. Fraietta, Simon F. Lacey, Elena J. Orlando, Iulian Pruteanu-Malinici, Mercy Gohil, Stefan Lundh, Alina C. Boesteanu, Yan Wang, Roddy S. O’Connor, Wei‐Ting Hwang, Edward Pequignot, David E Ambrose, Changfeng Zhang, Nicholas S. Wilcox, Felipe Bedoya, Corin L. Dorfmeier, Chen Fang, Lifeng Tian, Harit Parakandi, Minnal Gupta, Regina M. Young, F. Brad Johnson, Irina Kulikovskaya, Li Liu, Jun Xu, Sadik H. Kassim, Megan M. Davis, Bruce L. Levine, Noelle V. Frey, Donald L. Siegel, Alexander C. Huang, E. John Wherry, Hans Bitter, Jennifer L. Brogdon, David L. Porter, Carl H. June, J. Joseph Melenhorst - Nature Medicine 2018 cited by 1,770

  6. Defining ‘T cell exhaustion’

    Authors: Christian U. Blank, W. Nicholas Haining, Werner Held, Patrick G. Hogan, Axel Kallies, Enrico Lugli, Rachel C. Lynn, Mary Philip, Anjana Rao, Nicholas P. Restifo, Andrea Schietinger, Ton N. Schumacher, Pamela L. Schwartzberg, Arlene H. Sharpe, Daniel E. Speiser, E. John Wherry, Ben Youngblood, Dietmar Zehn - Nature reviews. Immunology 2019 cited by 1,584

  7. TOX transcriptionally and epigenetically programs CD8+ T cell exhaustion

    Authors: Omar Khan, Josephine R. Giles, Sierra J. McDonald, Sasikanth Manne, Shin Foong Ngiow, Kunal P. Patel, Michael T. Werner, Alexander C. Huang, Katherine A. Alexander, Jennifer E. Wu, John Attanasio, Patrick Yan, Sangeeth M. George, Bertram Bengsch, Ryan P. Staupe, Greg Donahue, Wei Xu, Ravi K. Amaravadi, Xiaowei Xu, Giorgos C. Karakousis, Tara C. Mitchell, Lynn M. Schuchter, Jonathan Kaye, Shelley L. Berger, E. John Wherry - Nature 2019 cited by 1,661

  8. Decade-long leukaemia remissions with persistence of CD4+ CAR T cells

    Authors: J. Joseph Melenhorst, Gregory M. Chen, Meng Wang, David L. Porter, Changya Chen, McKensie Collins, Peng Gao, Shovik Bandyopadhyay, Hongxing Sun, Ziran Zhao, Stefan Lundh, Iulian Pruteanu-Malinici, Christopher L. Nobles, Sayantan Maji, Noelle V. Frey, Saar Gill, Alison W. Loren, Lifeng Tian, Irina Kulikovskaya, Minnal Gupta, David E Ambrose, Megan M. Davis, Joseph A. Fraietta, Jennifer L. Brogdon, Regina M. Young, Anne Chew, Bruce L. Levine, Donald L. Siegel, Cécile Alanio, E. John Wherry, Frederic D. Bushman, Simon F. Lacey, Kai Tan, Carl H. June - Nature 2022 cited by 947

  9. Developmental Relationships of Four Exhausted CD8+ T Cell Subsets Reveals Underlying Transcriptional and Epigenetic Landscape Control Mechanisms

    Authors: Jean‐Christophe Beltra, Sasikanth Manne, Mohamed S. Abdel-Hakeem, Makoto Kurachi, Josephine R. Giles, Zeyu Chen, Valentina Casella, Shin Foong Ngiow, Omar Khan, Yinghui Huang, Patrick Yan, Kito Nzingha, Wei Xu, Ravi K. Amaravadi, Xiaowei Xu, Giorgos C. Karakousis, Tara C. Mitchell, Lynn M. Schuchter, Alexander C. Huang, E. John Wherry - Immunity 2020 cited by 1,065

  10. Tumor Interferon Signaling Regulates a Multigenic Resistance Program to Immune Checkpoint Blockade

    Authors: Joseph L. Benci, Bihui Xu, Yu Qiu, Tony J. Wu, Hannah Dada, Christina Twyman-Saint Victor, Lisa Cucolo, David S.M. Lee, Kristen E. Pauken, Alexander C. Huang, Tara C. Gangadhar, Ravi K. Amaravadi, Lynn M. Schuchter, Michael D. Feldman, Hemant Ishwaran, Robert H. Vonderheide, Amit Maity, E. John Wherry, Andy J. Minn - Cell 2016 cited by 1,194

  11. Radiation and dual checkpoint blockade activate non-redundant immune mechanisms in cancer

    Authors: Christina Twyman-Saint Victor, Andrew J. Rech, Amit Maity, Ramesh Rengan, Kristen E. Pauken, Erietta Stelekati, Joseph L. Benci, Bihui Xu, Hannah Dada, Pamela M. Odorizzi, Ramin S. Herati, Kathleen D. Mansfield, Dana Patsch, Ravi K. Amaravadi, Lynn M. Schuchter, Hemant Ishwaran, Rosemarie Mick, Daniel A. Pryma, Xiaowei Xu, Michael D. Feldman, Tara C. Gangadhar, Stephen M. Hahn, E. John Wherry, Robert H. Vonderheide, Andy J. Minn - Nature 2015 cited by 2,431

  12. Epigenetic stability of exhausted T cells limits durability of reinvigoration by PD-1 blockade

    Authors: Kristen E. Pauken, Morgan A. Sammons, Pamela M. Odorizzi, Sasikanth Manne, Jernej Godec, Omar Khan, Adam Drake, Zeyu Chen, Debattama R. Sen, Makoto Kurachi, R. Anthony Barnitz, Caroline Bartman, Bertram Bengsch, Alexander C. Huang, Jason M. Schenkel, Golnaz Vahedi, W. Nicholas Haining, Shelley L. Berger, E. John Wherry - Science 2016 cited by 1,348

  13. CD8+ T cells in the cancer-immunity cycle

    Authors: Josephine R. Giles, Anna-Maria Globig, Susan M. Kaech, E. John Wherry - Immunity 2023 cited by 396

  14. Molecular Signature of CD8+ T Cell Exhaustion during Chronic Viral Infection

    Authors: E. John Wherry, Sang‐Jun Ha, Susan M. Kaech, W. Nicholas Haining, Surojit Sarkar, Vandana Kalia, Shruti Subramaniam, Joseph N. Blattman, Daniel L. Barber, Rafi Ahmed - Immunity 2007 cited by 2,130

  15. Restoring function in exhausted CD8 T cells during chronic viral infection

    Authors: Daniel L. Barber, E. John Wherry, David Masopust, Baogong Zhu, James P. Allison, Arlene H. Sharpe, Gordon J. Freeman, Rafi Ahmed - Nature 2005 cited by 3,998

  16. T-cell invigoration to tumour burden ratio associated with anti-PD-1 response

    Authors: Alexander C. Huang, Michael A. Postow, Robert J. Orlowski, Rosemarie Mick, Bertram Bengsch, Sasikanth Manne, Wei Xu, Shannon Harmon, Josephine R. Giles, Brandon M. Wenz, Matthew Adamow, Deborah Kuk, Katherine S. Panageas, Cristina Carrera, Phillip Wong, Felix Quagliarello, Bradley Wubbenhorst, Kurt D’Andrea, Kristen E. Pauken, Ramin S. Herati, Ryan P. Staupe, Jason M. Schenkel, Suzanne McGettigan, Shawn Kothari, Sangeeth M. George, Robert H. Vonderheide, Ravi K. Amaravadi, Giorgos C. Karakousis, Lynn M. Schuchter, Xiaowei Xu, Katherine L. Nathanson, Jedd D. Wolchok, Tara C. Gangadhar, E. John Wherry - Nature 2017 cited by 1,690

  17. TCF-1-Centered Transcriptional Network Drives an Effector versus Exhausted CD8 T Cell-Fate Decision

    Authors: Zeyu Chen, Zhicheng Ji, Shin Foong Ngiow, Sasikanth Manne, Zhangying Cai, Alexander C. Huang, John L. Johnson, Ryan P. Staupe, Bertram Bengsch, Caiyue Xu, Sixiang Yu, Makoto Kurachi, Ramin S. Herati, Laura A. Vella, Amy E. Baxter, Jennifer E. Wu, Omar Khan, Jean‐Christophe Beltra, Josephine R. Giles, Erietta Stelekati, Laura M. McLane, Chi Wai Lau, Xiaolu Yang, Shelley L. Berger, Golnaz Vahedi, Hongkai Ji, E. John Wherry - Immunity 2019 cited by 711

  18. Serotonin reduction in post-acute sequelae of viral infection

    Authors: Andrea C. Wong, Ashwarya S. Devason, Iboro C. Umana, Timothy Cox, Lenka Dohnalová, Lev Litichevskiy, Jonathan Perla, Patrick Lundgren, Zienab Etwebi, Luke Izzo, Jihee Kim, Monika Tetlak, Hélène C. Descamps, Simone L. Park, Stephen Wisser, Aaron D. McKnight, Ryan D. Pardy, Junwon Kim, Niklas Blank, Shaan Patel, Katharina Thum, Sydney Mason, Jean‐Christophe Beltra, Michaël F. Michieletto, Shin Foong Ngiow, Brittany Miller, Megan J. Liou, Bhoomi Madhu, Oxana Dmitrieva-Posocco, Alex S. Huber, Peter Hewins, Christopher Petucci, Candice P. Chu, Gwen Baraniecki‐Zwil, Leila B. Giron, Amy E. Baxter, Allison R. Greenplate, Charlotte Kearns, Kathleen T. Montone, Leslie A. Litzky, Michael D. Feldman, Jorge Henao‐Mejia, Boris Striepen, Holly Ramage, Kellie A. Jurado, Kathryn E. Wellen, Una O’Doherty, Mohamed Abdel‐Mohsen, Alan Landay, Ali Keshavarzian, Timothy J. Henrich, Steven G. Deeks, Michael J. Peluso, Nuala J. Meyer, E. John Wherry, Benjamin Abramoff, Sara Cherry, Christoph A. Thaiss, Maayan Levy - Cell 2023 cited by 366

  19. SARS-CoV-2 reservoir in post-acute sequelae of COVID-19 (PASC)

    Authors: Amy D. Proal, Michael B. VanElzakker, Soo Aleman, Katie Bach, Brittany P. Boribong, Marcus Buggert, Sara Cherry, Daniel S. Chertow, Helen Davies, Christopher L. Dupont, Steven G. Deeks, William A. Eimer, E. Wesley Ely, Alessio Fasano, Marcelo Freire, Linda N. Geng, Diane E. Griffin, Timothy J. Henrich, Akiko Iwasaki, David Izquierdo‐Garcia, Michela Locci, Saurabh Mehandru, Mark M. Painter, Michael J. Peluso, Etheresia Pretorius, David A. Price, David Putrino, Richard H. Scheuermann, Gene S. Tan, Rudolph E. Tanzi, Henry F. VanBrocklin, Lael M. Yonker, E. John Wherry - Nature Immunology 2023 cited by 283

  20. The epigenetic landscape of T cell exhaustion

    Authors: Debattama R. Sen, James J. Kaminski, R. Anthony Barnitz, Makoto Kurachi, Ulrike Gerdemann, Kathleen B. Yates, Hsiao‐Wei Tsao, Jernej Godec, Martin W. LaFleur, Flavian D. Brown, Pierre Tonnerre, Raymond T. Chung, Damien C. Tully, Todd M. Allen, Nicole Frahm, Georg M. Lauer, E. John Wherry, Nir Yosef, W. Nicholas Haining - Science 2016 cited by 990

  21. Bioenergetic Insufficiencies Due to Metabolic Alterations Regulated by the Inhibitory Receptor PD-1 Are an Early Driver of CD8 + T Cell Exhaustion

    Authors: Bertram Bengsch, Andy L. Johnson, Makoto Kurachi, Pamela M. Odorizzi, Kristen E. Pauken, John Attanasio, Erietta Stelekati, Laura M. McLane, Michael Paley, Greg M. Delgoffe, E. John Wherry - Immunity 2016 cited by 829

  22. Sotigalimab and/or nivolumab with chemotherapy in first-line metastatic pancreatic cancer: clinical and immunologic analyses from the randomized phase 2 PRINCE trial

    Authors: Lacey Padrón, Deena M. Maurer, Mark H. O’Hara, Eileen M. O’Reilly, Robert A. Wolff, Zev A. Wainberg, Andrew H. Ko, George A. Fisher, Osama E. Rahma, Jaclyn P. Lyman, Christopher R. Cabanski, Jia Xin Yu, Shannon M. Pfeiffer, Marko Spasić, Jingying Xu, Pier Federico Gherardini, Joyson Karakunnel, Rosemarie Mick, Cécile Alanio, Katelyn T. Byrne, Travis J. Hollmann, Jonni S. Moore, Derek D. Jones, Marco Tognetti, Richard Chen, Xiaodong Yang, Lisa Salvador, E. John Wherry, Ute Dugan, Jill O’Donnell-Tormey, Lisa H. Butterfield, Vanessa M. Hubbard-Lucey, Ramy Ibrahim, Justin Fairchild, Samantha Bucktrout, Theresa LaVallee, Robert H. Vonderheide - Nature Medicine 2022 cited by 350

  23. mRNA vaccines induce durable immune memory to SARS-CoV-2 and variants of concern

    Authors: Rishi R. Goel, Mark M. Painter, Sokratis A. Apostolidis, Divij Mathew, Wenzhao Meng, Aaron M. Rosenfeld, Kendall A. Lundgreen, Arnold Reynaldi, David S. Khoury, Ajinkya Pattekar, Sigrid Gouma, Leticia Kuri-Cervantes, Philip Hicks, Sarah Dysinger, Amanda Hicks, Harsh Sharma, Sarah Herring, Scott W. Korte, Amy E. Baxter, Derek A. Oldridge, Josephine R. Giles, Madison E. Weirick, Christopher M. McAllister, Moses Awofolaju, Nicole Tanenbaum, Elizabeth M. Drapeau, Jeanette Dougherty, Sherea Long, Kurt D’Andrea, Jacob T. Hamilton, M. A. McLaughlin, Justine C. Williams, Sharon Adamski, Oliva Kuthuru, The UPenn COVID Processing Unit‡, Ian Frank, Michael R. Betts, Laura A. Vella, Alba Grifoni, Daniela Weiskopf, Alessandro Sette, Scott E. Hensley, Miles P. Davenport, Paul Bates, Eline T. Luning Prak, Allison R. Greenplate, E. John Wherry - Science 2021 cited by 947

  24. The enteric nervous system relays psychological stress to intestinal inflammation

    Authors: Kai Markus Schneider, Niklas Blank, Yelina Alvarez, Katharina Thum, Patrick Lundgren, Lev Litichevskiy, Madeleine Sleeman, Klaas Bahnsen, Jihee Kim, Simon Kardo, Shaan Patel, Lenka Dohnalová, Giulia T. Uhr, Hélène C. Descamps, Susanna Kircher, Alana M. McSween, Ashkan Rezazadeh Ardabili, Kelsey M Nemec, Monica T. Jimenez, Lila Glotfelty, Joshua D. Eisenberg, Emma E. Furth, Jorge Henao‐Mejia, F. Chris Bennett, Marie J. Pierik, Mariëlle Romberg‐Camps, Zlatan Mujagic, Marco Prinz, Carolin V. Schneider, E. John Wherry, Meenakshi Bewtra, Robert O. Heuckeroth, Maayan Levy, Christoph A. Thaiss - Cell 2023 cited by 333