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W. Nicholas Haining

Active 1999–2024

52
Papers
24,316
Citations
45
h-index
49
i10-index

Citations

Citations per year for W. Nicholas Haining1957: 1 citations1987: 1 citations1994: 1 citations1999: 4 citations2000: 10 citations2001: 5 citations2002: 7 citations2003: 3 citations2004: 1 citations2007: 2 citations2008: 19 citations2009: 78 citations2010: 118 citations2011: 155 citations2012: 180 citations2013: 178 citations2014: 138 citations2015: 220 citations2016: 249 citations2017: 351 citations2018: 514 citations2019: 1,158 citations2020: 1,591 citations2021: 1,700 citations2022: 1,414 citations2023: 1,246 citations2024: 1,614 citations2025: 854 citations2026: 50 citations1958–1986: no citations, so these years are not shown1988–1993: no citations, so these years are not shown1995–1998: no citations, so these years are not shown2005–2006: no citations, so these years are not shown

Citation sources

Countries

World map of the countries and regions citing this authorUnited States: 4,626 citing papers, 33.1% of this breakdownChina: 1,970 citing papers, 14.1% of this breakdownGermany: 774 citing papers, 5.5% of this breakdownUnited Kingdom: 751 citing papers, 5.4% of this breakdownFrance: 486 citing papers, 3.5% of this breakdownAustralia: 460 citing papers, 3.3% of this breakdownCanada: 423 citing papers, 3% of this breakdownSwitzerland: 390 citing papers, 2.8% of this breakdownJapan: 382 citing papers, 2.7% of this breakdownNetherlands: 366 citing papers, 2.6% of this breakdownItaly: 362 citing papers, 2.6% of this breakdownSpain: 261 citing papers, 1.9% of this breakdown
0%33.1%Other 19.5%

Institutions

Fields

  • Medicine45%
  • Immunology and Microbiology30.3%
  • Biochemistry, Genetics and Molecular Biology21.7%
  • Neuroscience1.1%
  • Engineering0.8%
  • Agricultural and Biological Sciences0.3%
  • Other0.8%

Topics

  • Immune Cell Function and Interaction12.1%
  • Cancer Immunotherapy and Biomarkers9.9%
  • Immunotherapy and Immune Responses7.6%
  • CAR-T cell therapy research6.7%
  • T-cell and B-cell Immunology6.7%
  • Immune cells in cancer3.1%
  • Other53.9%

Coauthors

All papers

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  1. Subsets of exhausted CD8+ T cells differentially mediate tumor control and respond to checkpoint blockade

    Authors: Brian C. Miller, Debattama R. Sen, Rose Al Abosy, Kevin Bi, Yamini V. Virkud, Martin W. LaFleur, Kathleen B. Yates, Ana Lako, Kristen D. Felt, Girish S. Naik, Michael P. Manos, Evisa Gjini, Juhi R. Kuchroo, Jeffrey J. Ishizuka, Jenna L. Collier, Gabriel K. Griffin, Seth Maleri, Dawn E. Comstock, Sarah A. Weiss, Flavian D. Brown, Arpit Panda, Margaret D. Zimmer, Robert T. Manguso, F. Stephen Hodi, Scott J. Rodig, Arlene H. Sharpe, W. Nicholas Haining - Nature Immunology 2019 cited by 2,072

  2. Defining ‘T cell exhaustion’

    Authors: Christian U. Blank, W. Nicholas Haining, Werner Held, Patrick G. Hogan, Axel Kallies, Enrico Lugli, Rachel C. Lynn, Mary Philip, Anjana Rao, Nicholas P. Restifo, Andrea Schietinger, Ton N. Schumacher, Pamela L. Schwartzberg, Arlene H. Sharpe, Daniel E. Speiser, E. John Wherry, Ben Youngblood, Dietmar Zehn - Nature reviews. Immunology 2019 cited by 1,584

  3. Epigenetic stability of exhausted T cells limits durability of reinvigoration by PD-1 blockade

    Authors: Kristen E. Pauken, Morgan A. Sammons, Pamela M. Odorizzi, Sasikanth Manne, Jernej Godec, Omar Khan, Adam Drake, Zeyu Chen, Debattama R. Sen, Makoto Kurachi, R. Anthony Barnitz, Caroline Bartman, Bertram Bengsch, Alexander C. Huang, Jason M. Schenkel, Golnaz Vahedi, W. Nicholas Haining, Shelley L. Berger, E. John Wherry - Science 2016 cited by 1,348

  4. Molecular Signature of CD8+ T Cell Exhaustion during Chronic Viral Infection

    Authors: E. John Wherry, Sang‐Jun Ha, Susan M. Kaech, W. Nicholas Haining, Surojit Sarkar, Vandana Kalia, Shruti Subramaniam, Joseph N. Blattman, Daniel L. Barber, Rafi Ahmed - Immunity 2007 cited by 2,130

  5. In vivo CRISPR screening identifies Ptpn2 as a cancer immunotherapy target

    Authors: Robert T. Manguso, Hans W. Pope, Margaret D. Zimmer, Flavian D. Brown, Kathleen B. Yates, Brian C. Miller, Natalie B. Collins, Kevin Bi, Martin W. LaFleur, Vikram R. Juneja, Sarah A. Weiss, Jennifer A. Lo, David E. Fisher, Diana Miao, Eliezer M. Van Allen, David E. Root, Arlene H. Sharpe, John G. Doench, W. Nicholas Haining - Nature 2017 cited by 1,172

  6. The epigenetic landscape of T cell exhaustion

    Authors: Debattama R. Sen, James J. Kaminski, R. Anthony Barnitz, Makoto Kurachi, Ulrike Gerdemann, Kathleen B. Yates, Hsiao‐Wei Tsao, Jernej Godec, Martin W. LaFleur, Flavian D. Brown, Pierre Tonnerre, Raymond T. Chung, Damien C. Tully, Todd M. Allen, Nicole Frahm, Georg M. Lauer, E. John Wherry, Nir Yosef, W. Nicholas Haining - Science 2016 cited by 990

  7. Coregulation of CD8+ T cell exhaustion by multiple inhibitory receptors during chronic viral infection

    Authors: Shawn D. Blackburn, Haina Shin, W. Nicholas Haining, Tao Zou, Creg J. Workman, Antonio Polley, Michael R. Betts, Gordon J. Freeman, Dario A.A. Vignali, E. John Wherry - Nature Immunology 2008 cited by 2,058

  8. Epigenetic silencing by SETDB1 suppresses tumour intrinsic immunogenicity

    Authors: Gabriel K. Griffin, Jingyi Wu, Arvin Iracheta‐Vellve, James C. Patti, Jeffrey Hsu, Thomas Davis, Deborah Dele‐Oni, Peter P. Du, Aya Halawi, Jeffrey J. Ishizuka, Sarah Kim, Susan Klaeger, Nelson H. Knudsen, Brian C. Miller, Tung H. Nguyen, Kira E. Olander, Malvina Papanastasiou, Suzanna Rachimi, Emily Robitschek, Emily M. Schneider, Mitchell D. Yeary, Margaret D. Zimmer, Jacob D. Jaffe, Steven A. Carr, John G. Doench, W. Nicholas Haining, Kathleen B. Yates, Robert T. Manguso, B Bernstein - Nature 2021 cited by 362

  9. CDK4/6 Inhibition Augments Antitumor Immunity by Enhancing T-cell Activation

    Authors: Jiehui Deng, Eric S. Wang, Russell W. Jenkins, Shuai Li, Ruben Dries, Kathleen Yates, Sandeep Chhabra, Wei Huang, Hongye Liu, Amir Reza Aref, Elena V. Ivanova, Cloud P. Paweletz, Michaela Bowden, Chensheng W. Zhou, Grit S. Herter-Sprie, Jessica A. Sorrentino, John Bisi, Patrick H. Lizotte, Ashley A. Merlino, Max M. Quinn, Lauren E. Bufe, Annan Yang, Y. Zhang, Hua Zhang, Peng Gao, Ting Chen, Megan E. Cavanaugh, Amanda J. Rode, Eric Haines, Patrick J. Roberts, Jay C. Strum, William G. Richards, Jochen H. Lorch, Sareh Parangi, Viswanath Gunda, Genevieve M. Boland, Raphael Bueno, Sangeetha Palakurthi, Gordon J. Freeman, Jerome Ritz, W. Nicholas Haining, Norman E. Sharpless, Haribabu Arthanari, Geoffrey I. Shapiro, David A. Barbie, Nathanael S. Gray, Kwok‐Kin Wong - Cancer Discovery 2017 cited by 781

  10. Loss of ADAR1 in tumours overcomes resistance to immune checkpoint blockade

    Authors: Jeffrey J. Ishizuka, Robert T. Manguso, Collins Cheruiyot, Kevin Bi, Arpit Panda, Arvin Iracheta‐Vellve, Brian C. Miller, Peter P. Du, Kathleen B. Yates, Juan Dubrot, Ilana Buchumenski, Dawn E. Comstock, Flavian D. Brown, Austin Ayer, Ian C. Kohnle, Hans W. Pope, Margaret D. Zimmer, Debattama R. Sen, Sarah Kate Lane-Reticker, Emily Robitschek, Gabriel K. Griffin, Natalie B. Collins, Adrienne H. Long, John G. Doench, David Kozono, Erez Y. Levanon, W. Nicholas Haining - Nature 2018 cited by 728

  11. PD-L1 on tumor cells is sufficient for immune evasion in immunogenic tumors and inhibits CD8 T cell cytotoxicity

    Authors: Vikram R. Juneja, Kathleen A. McGuire, Robert T. Manguso, Martin W. LaFleur, Natalie B. Collins, W. Nicholas Haining, Gordon J. Freeman, Arlene H. Sharpe - The Journal of Experimental Medicine 2017 cited by 877

  12. Normalizing the environment recapitulates adult human immune traits in laboratory mice

    Authors: Lalit K. Beura, Sara E. Hamilton, Kevin Bi, Jason M. Schenkel, Oludare A. Odumade, Kerry A. Casey, Emily A. Thompson, Kathryn Fraser, Pamela C. Rosato, Ali Filali‐Mouhim, Rafick‐Pierre Sékaly, Marc K. Jenkins, Vaiva Vezys, W. Nicholas Haining, Stephen C. Jameson, David Masopust - Nature 2016 cited by 1,096

  13. In vivo CRISPR screens reveal the landscape of immune evasion pathways across cancer

    Authors: Juan Dubrot, Peter P. Du, Sarah Kate Lane-Reticker, Emily Kessler, Audrey J. Muscato, Arnav Mehta, Samuel S. Freeman, Peter M. Allen, Kira E. Olander, Kyle Ockerman, Clara Wolfe, Fabius Wiesmann, Nelson H. Knudsen, Hsiao‐Wei Tsao, Arvin Iracheta‐Vellve, Emily M. Schneider, Andrea N. Rivera-Rosario, Ian C. Kohnle, Hans W. Pope, Austin Ayer, Gargi Mishra, Margaret D. Zimmer, Sarah Kim, Animesh Mahapatra, Hakimeh Ebrahimi-Nik, Dennie T. Frederick, Genevieve M. Boland, W. Nicholas Haining, David E. Root, John G. Doench, Nir Hacohen, Kathleen B. Yates, Robert T. Manguso - Nature Immunology 2022 cited by 222

  14. Epigenetic scars of CD8+ T cell exhaustion persist after cure of chronic infection in humans

    Authors: Kathleen B. Yates, Pierre Tonnerre, Geneviève Martin, Ulrike Gerdemann, Rose Al Abosy, Dawn E. Comstock, Sarah A. Weiss, David Wolski, Damien C. Tully, Raymond T. Chung, Todd M. Allen, Arthur Y. Kim, Sarah Fidler, Julie Fox, John Frater, Georg M. Lauer, W. Nicholas Haining, Debattama R. Sen - Nature Immunology 2021 cited by 242

  15. PTPN2 regulates the generation of exhausted CD8+ T cell subpopulations and restrains tumor immunity

    Authors: Martin W. LaFleur, Thao H. Nguyen, Matthew Coxe, Brian C. Miller, Kathleen B. Yates, Jacob E. Gillis, Debattama R. Sen, Emily F. Gaudiano, Rose Al Abosy, Gordon J. Freeman, W. Nicholas Haining, Arlene H. Sharpe - Nature Immunology 2019 cited by 247

  16. Origin and differentiation of human memory CD8 T cells after vaccination

    Authors: Rama Akondy, Mark Fitch, Srilatha Edupuganti, Shu Yang, Haydn Kissick, Kelvin W. Li, Ben Youngblood, Hossam A. Abdelsamed, Donald J. McGuire, Kristen W. Cohen, Gabriela Alexe, Shashi Nagar, Megan McCausland, Gupta Sk, Pramila Tata, W. Nicholas Haining, M. Juliana McElrath, David Zhang, Bin Hu, William J. Greenleaf, Jörg J. Goronzy, Mark J. Mulligan, Marc K. Hellerstein, Rafi Ahmed - Nature 2017 cited by 533

  17. CD39 Expression Identifies Terminally Exhausted CD8+ T Cells

    Authors: Prakash Gupta, Jernej Godec, David Wolski, Emily Adland, Kathleen B. Yates, Kristen E. Pauken, Cormac Cosgrove, Carola Ledderose, Wolfgang G. Junger, Simon C. Robson, E. John Wherry, Galit Alter, Philip Goulder, Paul Klenerman, Arlene H. Sharpe, Georg M. Lauer, W. Nicholas Haining - PLoS Pathogens 2015 cited by 390

  18. Densely Interconnected Transcriptional Circuits Control Cell States in Human Hematopoiesis

    Authors: Noa Novershtern, Aravind Subramanian, Lee N. Lawton, Raymond H. Mak, W. Nicholas Haining, Marie McConkey, Naomi Habib, Nir Yosef, Cindy Y. Chang, Tal Shay, Garrett M. Frampton, Adam Drake, Ilya Leskov, Björn Nilsson, Fred Preffer, David Dombkowski, John Evans, Ted Liefeld, John S. Smutko, Jianzhu Chen, Nir Friedman, Richard A. Young, Todd R. Golub, Aviv Regev, Benjamin L. Ebert - Cell 2011 cited by 1,001

  19. The transcription factor BATF operates as an essential differentiation checkpoint in early effector CD8+ T cells

    Authors: Makoto Kurachi, R. Anthony Barnitz, Nir Yosef, Pamela M. Odorizzi, Michael DiIorio, Madeleine E. Lemieux, Kathleen B. Yates, Jernej Godec, Martin G. Klatt, Aviv Regev, E. John Wherry, W. Nicholas Haining - Nature Immunology 2014 cited by 393

  20. Stable inhibitory activity of regulatory T cells requires the transcription factor Helios

    Authors: Hye‐Jung Kim, R. Anthony Barnitz, Taras Kreslavsky, Flavian D. Brown, Howell Moffett, Madeleine E. Lemieux, Yasemin Kaygusuz, Torsten Meißner, Tobias A.W. Holderried, Susan Chan, Philippe Kastner, W. Nicholas Haining, Harvey Cantor - Science 2015 cited by 428

  21. Transcriptional analysis of HIV-specific CD8+ T cells shows that PD-1 inhibits T cell function by upregulating BATF

    Authors: Michael Quigley, Florencia Pereyra, Björn Nilsson, Filippos Porichis, Catia Fonseca, Quentin Eichbaum, Boris Jülg, Jonathan L. Jesneck, Kathleen Brosnahan, Sabrina Imam, Kate Russell, Ildikó Y. Tóth, Alicja Piechocka‐Trocha, Douglas V. Dolfi, Jill Angelosanto, Alison Crawford, Haina Shin, Douglas S. Kwon, Jennifer Zupkosky, Loise M. Francisco, Gordon J. Freeman, E. John Wherry, Daniel E. Kaufmann, Bruce D. Walker, Benjamin L. Ebert, W. Nicholas Haining - Nature Medicine 2010 cited by 514

  22. Stepwise activities of mSWI/SNF family chromatin remodeling complexes direct T cell activation and exhaustion

    Authors: Elena Battistello, Kimberlee A. Hixon, Dawn E. Comstock, Clayton K. Collings, Xufeng Chen, Javier Rodríguez Hernáez, Soobeom Lee, Kasey S. Cervantes, Madeline M. Hinkley, Konstantinos Ntatsoulis, Annamaria Cesarano, Kathryn Hockemeyer, W. Nicholas Haining, Matthew T. Witkowski, Jun Qi, Aristotelis Tsirigos, Fabiana Perna, Iannis Aifantis, Cigall Kadoch - Molecular Cell 2023 cited by 72

  23. Functional and genomic profiling of effector CD8 T cell subsets with distinct memory fates

    Authors: Surojit Sarkar, Vandana Kalia, W. Nicholas Haining, Bogumila T. Konieczny, Shruti Subramaniam, Rafi Ahmed - The Journal of Experimental Medicine 2008 cited by 629

  24. PI3K activation allows immune evasion by promoting an inhibitory myeloid tumor microenvironment

    Authors: Natalie B. Collins, Rose Al Abosy, Brian C. Miller, Kevin Bi, Qihong Zhao, Michael Quigley, Jeffrey Ishizuka, Kathleen B. Yates, Hans W. Pope, Robert T Manguso, Yashaswi Shrestha, Marc H. Wadsworth, Tudor Hughes, Alex K. Shalek, Jesse S. Boehm, William C. Hahn, John G. Doench, W. Nicholas Haining - Journal for ImmunoTherapy of Cancer 2022 cited by 122