David J. Mangelsdorf
Active 1983–2025
- 168
- Papers
- 84,022
- Citations
- 129
- h-index
- 167
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Medicine45.4%
- Biochemistry, Genetics and Molecular Biology40.4%
- Neuroscience5.7%
- Immunology and Microbiology2.7%
- Pharmacology, Toxicology and Pharmaceutics1.4%
- Agricultural and Biological Sciences1.3%
- Other3.1%
Topics
- Drug Transport and Resistance Mechanisms5.2%
- Estrogen and related hormone effects4.8%
- Cholesterol and Lipid Metabolism4.6%
- Peroxisome Proliferator-Activated Receptors4.3%
- Retinoids in leukemia and cellular processes3.6%
- Liver Disease Diagnosis and Treatment3.3%
- Other74.2%
Coauthors
- Steven A. Kliewer56
- Ronald M. Evans27
- Angie L. Bookout23
- Joyce J. Repa22
- Yuan Zhang13
- Carolyn L. Cummins11
- Kazuhiko Umesono9
- Mark R. Haussler9
- Peter Tontonoz9
- Richard A. Heyman9
- Ruth T. Yu9
- Antonio Moschetta8
- Xunshan Ding8
- Bryn M. Owen7
- Makoto Makishima7
- Michael Downes7
- Robert D. Gerard7
- Sean B. Joseph7
- Bryan Laffitte6
- Daniel Motola6
- J. Wesley Pike6
- Matthew J. Potthoff6
- Michihisa Umetani6
- Mihwa Choi6
All papers
- Fibroblast growth factor 15 functions as an enterohepatic signal to regulate bile acid homeostasis
Authors: Takeshi Inagaki, Mihwa Choi, Antonio Moschetta, Li Peng, Carolyn L. Cummins, Jeffrey G. McDonald, Guizhen Luo, Stacey A. Jones, Bryan Goodwin, James A. Richardson, Robert D. Gerard, Joyce J. Repa, David J. Mangelsdorf, Steven A. Kliewer - Cell Metabolism 2005 cited by 1,798
- Regulation of antibacterial defense in the small intestine by the nuclear bile acid receptor
Authors: Takeshi Inagaki, Antonio Moschetta, Youn-Kyoung Lee, Li Peng, Guixiang Zhao, Michael Downes, Ruth T. Yu, John M. Shelton, James A. Richardson, Joyce J. Repa, David J. Mangelsdorf, Steven A. Kliewer - National Academy of Sciences, Proceedings of the National Academy of Sciences 2006 cited by 1,152
- Bile acids lower triglyceride levels via a pathway involving FXR, SHP, and SREBP-1c
Authors: Mitsuhiro Watanabe, Sander M. Houten, Li Wang, Antonio Moschetta, David J. Mangelsdorf, Richard A. Heyman, David D. Moore, Johan Auwerx - Journal of Clinical Investigation 2004 cited by 1,356
- Identification of a Nuclear Receptor for Bile Acids
Authors: Makoto Makishima, Arthur Y. Okamoto, Joyce J. Repa, Hua Tu, R. Marc Learned, Alvin Luk, Mitchell Hull, Kevin D. Lustig, David J. Mangelsdorf, Bei Shan - Science 1999 cited by 2,705
- Nuclear Receptors, RXR, and the Big Bang
Authors: Ronald M. Evans, David J. Mangelsdorf - Cell 2014 cited by 1,208
- The nuclear receptor superfamily: The second decade
Authors: David J. Mangelsdorf, Carl S. Thummel, Miguel Beato, Peter Herrlich, Günther Schütz, Kazuhiko Umesono, Bruce Blumberg, Philippe Kastner, Manuel Mark, Pierre Chambon, Ronald M. Evans - Cell 1995 cited by 6,986
- Endocrine Regulation of the Fasting Response by PPARα-Mediated Induction of Fibroblast Growth Factor 21
Authors: Takeshi Inagaki, Paul A. Dutchak, Guixiang Zhao, Xunshan Ding, Laurent Gautron, Vinay Parameswara, Yong Li, Regina Goetz, Moosa Mohammadi, Victoria Esser, Joel K. Elmquist, Robert D. Gerard, Shawn C. Burgess, Robert E. Hammer, David J. Mangelsdorf, Steven A. Kliewer - Cell Metabolism 2007 cited by 1,494
- Bile Acids as Hormones: The FXR-FGF15/19 Pathway
Authors: Steven A. Kliewer, David J. Mangelsdorf - Digestive Diseases 2015 cited by 415
- The energy balance model of obesity: beyond calories in, calories out
Authors: Kevin D. Hall, I. Sadaf Farooqi, Jeffery M. Friedman, Samuel Klein, Ruth J. F. Loos, David J. Mangelsdorf, Stephen O’Rahilly, Éric Ravussin, Leanne M. Redman, Donna H. Ryan, John R. Speakman, Deirdre K. Tobias - American Journal of Clinical Nutrition 2022 cited by 302
- Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRα and LXRβ
Authors: Joyce J. Repa, Guosheng Liang, Jiafu Ou, Yuriy K. Bashmakov, Jean‐Marc A. Lobaccaro, Iichiro Shimomura, Bei Shan, Michael S. Brown, J GOLDSTEIN, David J. Mangelsdorf - Genes & Development 2000 cited by 1,690
- Vitamin D Receptor As an Intestinal Bile Acid Sensor
Authors: Makoto Makishima, Timothy T. Lu, Wen Xie, G. Kerr Whitfield, Hideharu Domoto, Ronald M. Evans, Mark R. Haussler, David J. Mangelsdorf - Science 2002 cited by 1,171
- FGF19 as a Postprandial, Insulin-Independent Activator of Hepatic Protein and Glycogen Synthesis
Authors: Serkan Kır, Sara A. Beddow, Varman T. Samuel, Paul L. Miller, Stephen F. Previs, Kelly Suino-Powell, H. Eric Xu, Gerald I. Shulman, Steven A. Kliewer, David J. Mangelsdorf - Science 2011 cited by 623
- Circulating FGF21 Is Liver Derived and Enhances Glucose Uptake During Refeeding and Overfeeding
Authors: Kathleen R. Markan, Meghan C. Naber, Magdalene Ameka, Maxwell D. Anderegg, David J. Mangelsdorf, Steven A. Kliewer, Moosa Mohammadi, Matthew J. Potthoff - Diabetes 2014 cited by 583
- Role of LXRs in control of lipogenesis
Authors: Joshua R. Schultz, Hua Tu, Alvin Luk, Joyce J. Repa, Julio C. Medina, Leping Li, Susan W. Schwendner, Shelley Wang, Martin Thoolen, David J. Mangelsdorf, Kevin D. Lustig, Bei Shan - Genes & Development 2000 cited by 1,667
- FGF21 Acts Centrally to Induce Sympathetic Nerve Activity, Energy Expenditure, and Weight Loss
Authors: Bryn M. Owen, Xunshan Ding, Donald A. Morgan, Katie C. Coate, Angie L. Bookout, Kamal Rahmouni, Steven A. Kliewer, David J. Mangelsdorf - Cell Metabolism 2014 cited by 511
- A Dozen Years of Discovery: Insights into the Physiology and Pharmacology of FGF21
Authors: Steven A. Kliewer, David J. Mangelsdorf - Cell Metabolism 2019 cited by 270
- FGF21 induces PGC-1α and regulates carbohydrate and fatty acid metabolism during the adaptive starvation response
Authors: Matthew J. Potthoff, Takeshi Inagaki, Santhosh Satapati, Xunshan Ding, TianTeng He, Regina Goetz, Moosa Mohammadi, Brian N. Finck, David J. Mangelsdorf, Steven A. Kliewer, Shawn C. Burgess - National Academy of Sciences, Proceedings of the National Academy of Sciences 2009 cited by 694
- Research Resource: Comprehensive Expression Atlas of the Fibroblast Growth Factor System in Adult Mouse
Authors: Klementina Fon Tacer, Angie L. Bookout, Xunshan Ding, Hiroshi Kurosu, George B. John, Lei Wang, Regina Goetz, Moosa Mohammadi, Makoto Kuro‐o, David J. Mangelsdorf, Steven A. Kliewer - Molecular Endocrinology 2010 cited by 686
- Reciprocal regulation of inflammation and lipid metabolism by liver X receptors
Authors: Sean B. Joseph, Antonio Castrillo, Bryan Laffitte, David J. Mangelsdorf, Peter Tontonoz - Nature Medicine 2003 cited by 1,139
- FGF21 regulates metabolism and circadian behavior by acting on the nervous system
Authors: Angie L. Bookout, Marleen H. M. de Groot, Bryn M. Owen, Syann Lee, Laurent Gautron, Heather L Lawrence, Xunshan Ding, Joel K. Elmquist, Joseph S. Takahashi, David J. Mangelsdorf, Steven A. Kliewer - Nature Medicine 2013 cited by 537
- Molecular Basis for Feedback Regulation of Bile Acid Synthesis by Nuclear Receptors
Authors: Timothy T. Lu, Makoto Makishima, Joyce J. Repa, Kristina Schoonjans, Thomas A. Kerr, Johan Auwerx, David J. Mangelsdorf - Molecular Cell 2000 cited by 1,475
- FGF15/19 Regulates Hepatic Glucose Metabolism by Inhibiting the CREB-PGC-1α Pathway
Authors: Matthew J. Potthoff, Jamie Bonéy-Montoya, Mihwa Choi, TianTeng He, Nishanth E. Sunny, Santhosh Satapati, Kelly Suino-Powell, H. Eric Xu, Robert D. Gerard, Brian N. Finck, Shawn C. Burgess, David J. Mangelsdorf, Steven A. Kliewer - Cell Metabolism 2011 cited by 421
- FGF19, FGF21, and an FGFR1/β-Klotho-Activating Antibody Act on the Nervous System to Regulate Body Weight and Glycemia
Authors: Tian Lan, Donald A. Morgan, Kamal Rahmouni, Junichiro Sonoda, Xiaorong Fu, Shawn C. Burgess, William L. Holland, Steven A. Kliewer, David J. Mangelsdorf - Cell Metabolism 2017 cited by 251
- Endocrine fibroblast growth factors 15/19 and 21: from feast to famine
Authors: Matthew J. Potthoff, Steven A. Kliewer, David J. Mangelsdorf - Genes & Development 2012 cited by 433
