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Richard A. Heyman

Active 1986–2018

54
Papers
19,746
Citations
53
h-index
54
i10-index

Citations

Citations per year for Richard A. Heyman1987: 3 citations1988: 2 citations1989: 17 citations1990: 23 citations1991: 18 citations1992: 45 citations1993: 105 citations1994: 105 citations1995: 153 citations1996: 166 citations1997: 255 citations1998: 289 citations1999: 310 citations2000: 367 citations2001: 296 citations2002: 327 citations2003: 313 citations2004: 295 citations2005: 260 citations2006: 267 citations2007: 238 citations2008: 203 citations2009: 166 citations2010: 193 citations2011: 160 citations2012: 144 citations2013: 157 citations2014: 106 citations2015: 113 citations2016: 109 citations2017: 108 citations2018: 99 citations2019: 331 citations2020: 300 citations2021: 280 citations2022: 249 citations2023: 166 citations2024: 208 citations2025: 102 citations2026: 1 citations

Citation sources

Countries

World map of the countries and regions citing this authorUnited States: 3,135 citing papers, 40.9% of this breakdownChina: 607 citing papers, 7.9% of this breakdownFrance: 417 citing papers, 5.5% of this breakdownJapan: 393 citing papers, 5.1% of this breakdownUnited Kingdom: 376 citing papers, 4.9% of this breakdownCanada: 283 citing papers, 3.7% of this breakdownGermany: 278 citing papers, 3.6% of this breakdownItaly: 233 citing papers, 3.1% of this breakdownNetherlands: 187 citing papers, 2.5% of this breakdownSwitzerland: 176 citing papers, 2.3% of this breakdownSweden: 164 citing papers, 2.1% of this breakdownSpain: 147 citing papers, 1.9% of this breakdown
0%40.9%Other 16.5%

Institutions

Fields

  • Biochemistry, Genetics and Molecular Biology48.1%
  • Medicine41.5%
  • Neuroscience4.1%
  • Immunology and Microbiology2.5%
  • Agricultural and Biological Sciences0.9%
  • Pharmacology, Toxicology and Pharmaceutics0.8%
  • Other2.1%

Topics

  • Estrogen and related hormone effects6.8%
  • Peroxisome Proliferator-Activated Receptors6.7%
  • Retinoids in leukemia and cellular processes5.9%
  • Drug Transport and Resistance Mechanisms5.5%
  • Cholesterol and Lipid Metabolism5.5%
  • Adipose Tissue and Metabolism3.4%
  • Other66.2%

Coauthors

All papers

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  1. Bile acids lower triglyceride levels via a pathway involving FXR, SHP, and SREBP-1c

    Authors: Mitsuhiro Watanabe, Sander M. Houten, Li Wang, Antonio Moschetta, David J. Mangelsdorf, Richard A. Heyman, David D. Moore, Johan Auwerx - Journal of Clinical Investigation 2004 cited by 1,356

  2. ARN-509: A Novel Antiandrogen for Prostate Cancer Treatment

    Authors: Nicola J. Clegg, John Wongvipat, James D. Joseph, Chris Tran, Samedy Ouk, Anna Dilhas, Yu Chen, Kate Grillot, Eric D. Bischoff, Ling Cai, Anna Aparicio, Steven Dorow, Vivek Arora, Gang Shao, Jing Qian, Hong Zhao, Guangbin Yang, Chunyan Cao, John Sensintaffar, Teresa Wasielewska, Mark R. Herbert, Céline Bonnefous, Beatrice Darimont, Howard I. Scher, Peter Smith‐Jones, Mark Klang, Nicholas D. Smith, Elisa de Stanchina, Nian Wu, Ouathek Ouerfelli, Peter J. Rix, Richard A. Heyman, Michael E. Jung, Charles L. Sawyers, Jeffrey H. Hager - Cancer Research 2012 cited by 660

  3. Regulation of Absorption and ABC1-Mediated Efflux of Cholesterol by RXR Heterodimers

    Authors: Joyce J. Repa, S D Turley, Jean Marc Lobaccaro, Julio C. Medina, L. Li, Kevin D. Lustig, B Shan, Richard A. Heyman, John M. Dietschy, David J. Mangelsdorf - Science 2000 cited by 1,303

  4. 9-cis retinoic acid is a high affinity ligand for the retinoid X receptor

    Authors: Richard A. Heyman, David J. Mangelsdorf, Jacqueline A. Dyck, Robert B. Stein, Gregor Eichele, Ronald M. Evans, Christina Thaller - Cell 1992 cited by 1,805

  5. LXR, a nuclear receptor that defines a distinct retinoid response pathway.

    Authors: P J Willy, Kazuhiko Umesono, Estelita S. Ong, Ronald M. Evans, Richard A. Heyman, David J. Mangelsdorf - Genes & Development 1995 cited by 1,117

  6. Errα and Gabpa/b specify PGC-1α-dependent oxidative phosphorylation gene expression that is altered in diabetic muscle

    Authors: Vamsi K. Mootha, Christoph Handschin, Dan Arlow, Xiaohui Xie, Julie St‐Pierre, Smita Sihag, Wenli Yang, David Altshuler, Pere Puigserver, Nick Patterson, Patricia J. Willy, Ira G. Schulman, Richard A. Heyman, Eric S. Lander, Bruce M. Spiegelman - National Academy of Sciences, Proceedings of the National Academy of Sciences 2004 cited by 681

  7. A Natural Product That Lowers Cholesterol As an Antagonist Ligand for FXR

    Authors: Nancy L. Urizar, Amy B. Liverman, D'Nette T. Dodds, Frank Valentin Silva, Peter Ordentlich, Yingzhuo Yan, Frank J. Gonzalez, Richard A. Heyman, David J. Mangelsdorf, David D. Moore - Science 2002 cited by 548

  8. Convergence of 9-cis retinoic acid and peroxisome proliferator signalling pathways through heterodimer formation of their receptors

    Authors: Steven A. Kliewer, Kazuhiko Umesono, Daniel J. Noonan, Richard A. Heyman, Ronald M. Evans - Nature 1992 cited by 1,746

  9. Identification of macrophage liver X receptors as inhibitors of atherosclerosis

    Authors: Rajendra K. Tangirala, Eric D. Bischoff, Sean B. Joseph, Brandee Wagner, Robert Walczak, Bryan Laffitte, Chris Daige, Diane Thomas, Richard A. Heyman, David J. Mangelsdorf, Xuping Wang, Aldons J. Lusis, Peter Tontonoz, Ira G. Schulman - National Academy of Sciences, Proceedings of the National Academy of Sciences 2002 cited by 436

  10. A CBP Integrator Complex Mediates Transcriptional Activation and AP-1 Inhibition by Nuclear Receptors

    Authors: Yasutomi Kamei, Lan Xu, Thorsten Heinzel, Joseph Torchia, Riki Kurokawa, Bernd Gloss, Sheng‐Cai Lin, Richard A. Heyman, David W. Rose, Christopher K. Glass, Michael G. Rosenfeld - Cell 1996 cited by 2,181

  11. Macrophage Liver X Receptor Is Required for Antiatherogenic Activity of LXR Agonists

    Authors: Nancy Levin, Eric D. Bischoff, Chris Daige, Diane Thomas, Calvin Vu, Richard A. Heyman, Rajendra K. Tangirala, Ira G. Schulman - Arteriosclerosis Thrombosis and Vascular Biology 2004 cited by 281

  12. Regulation of PPARγ coactivator 1α (PGC-1α) signaling by an estrogen-related receptor α (ERRα) ligand

    Authors: Patricia J. Willy, Ian Murray, Jing Qian, Brett B. Busch, William C. Stevens, Richard Martin, Raju Mohan, Sihong Zhou, Peter Ordentlich, Ping Wei, Douglas W. Sapp, Robert A. Horlick, Richard A. Heyman, Ira G. Schulman - National Academy of Sciences, Proceedings of the National Academy of Sciences 2004 cited by 193

  13. The selective estrogen receptor downregulator GDC-0810 is efficacious in diverse models of ER+ breast cancer

    Authors: James D. Joseph, Beatrice Darimont, Wei Zhou, Alfonso Arrazate, Amy Young, Ellen Ingalla, Kimberly Walter, Robert A. Blake, Jim Nonomiya, Zhengyu Guan, Lorna Kategaya, Steven P. Govek, Andiliy Lai, Mehmet Kahraman, Dan Brigham, John Sensintaffar, Nhin Lu, Gang Shao, Jing Qian, Kate Grillot, Michael Moon, Rene Prudente, Eric D. Bischoff, Kyoung-Jin Lee, Céline Bonnefous, Karensa Douglas, Jackaline D Julien, Johnny Nagasawa, Anna Aparicio, Josh Kaufman, Benjamin Haley, Jennifer M. Giltnane, Ingrid E. Wertz, Mark R. Lackner, Michelle Nannini, Deepak Sampath, Luis J. Schwarz, Henry Charles Manning, Mohammed Noor Tantawy, Carlos L. Arteaga, Richard A. Heyman, Peter J. Rix, Lori S. Friedman, Nicholas D. Smith, Ciara Metcalfe, Jeffrey H. Hager - eLife 2016 cited by 119

  14. Redundant Pathways for Negative Feedback Regulation of Bile Acid Production

    Authors: Li Wang, Yoon‐Kwang Lee, Donnie S. Bundman, Yunqing Han, Sundararajah Thevananther, Changsoo Kim, Steven S. Chua, Ping Wei, Richard A. Heyman, Michael Karin, David D. Moore - Developmental Cell 2002 cited by 479

  15. Identification of GDC-0810 (ARN-810), an Orally Bioavailable Selective Estrogen Receptor Degrader (SERD) that Demonstrates Robust Activity in Tamoxifen-Resistant Breast Cancer Xenografts

    Authors: Andiliy Lai, Mehmet Kahraman, Steven P. Govek, Johnny Nagasawa, Céline Bonnefous, Jackie Julien, Karensa Douglas, John Sensintaffar, Nhin Lu, Kyoung‐Jin Lee, Anna Aparicio, Josh Kaufman, Jing Qian, Gang Shao, Rene Prudente, Michael Moon, James D. Joseph, Beatrice Darimont, Daniel Brigham, Kate Grillot, Richard A. Heyman, Peter J. Rix, Jeffrey H. Hager, Nicholas D. Smith - Journal of Medicinal Chemistry 2015 cited by 247

  16. Maximizing ER-α Degradation Maximizes Activity in a Tamoxifen-Resistant Breast Cancer Model: Identification of GDC-0927

    Authors: Mehmet Kahraman, Steven P. Govek, Johnny Nagasawa, Andiliy Lai, Céline Bonnefous, Karensa Douglas, John Sensintaffar, Nhin Liu, KyoungJin Lee, Anna Aparicio, Josh Kaufman, Jing Qian, Gang Shao, Rene Prudente, James D. Joseph, Beatrice Darimont, Daniel Brigham, Richard A. Heyman, Peter J. Rix, Jeffrey H. Hager, Nicholas D. Smith - ACS Medicinal Chemistry Letters 2018 cited by 76

  17. Promoter-Specific Roles for Liver X Receptor/Corepressor Complexes in the Regulation of ABCA1 and SREBP1 Gene Expression

    Authors: Brandee Wagner, Annabel F. Valledor, Gang Shao, Chris Daige, Eric D. Bischoff, Mary Petrowski, Kristen Jepsen, Sung Hee Baek, Richard A. Heyman, Michael G. Rosenfeld, Ira G. Schulman, Christopher K. Glass - Molecular and Cellular Biology 2003 cited by 238

  18. Low‐dose methotrexate treatment for moderate‐to‐severe atopic dermatitis in adults

    Authors: Anna Lyakhovitsky, Aviv Barzilai, Richard A. Heyman, Seth J. Baum, Boaz Amichai, Michal Solomon, D Shpiro, Henri Trau - Journal of the European Academy of Dermatology and Venereology 2009 cited by 101

  19. Reduction of atherosclerosis in apolipoprotein E knockout mice by activation of the retinoid X receptor

    Authors: Thierry Claudel, Mark D. Leibowitz, Catherine Fiévet, Anne Tailleux, Brandee Wagner, Joyce J. Repa, Gérard Torpier, Jean‐Marc A. Lobaccaro, James R. Paterniti, David J. Mangelsdorf, Richard A. Heyman, Johan Auwerx - National Academy of Sciences, Proceedings of the National Academy of Sciences 2001 cited by 291

  20. Differential effects of synthetic nuclear retinoid receptor-selective retinoids on the growth of human non-small cell lung carcinoma cells.

    Authors: Shi‐Yong Sun, Ping Yue, Marcia I. Dawson, Braham Shroot, Serge Michel, William W. Lamph, Richard A. Heyman, Min Teng, Roshantha A.S. Chandraratna, Koichi Shudo, Waun Ki Hong, Reuben Lotan - 1997 cited by 212

  21. Nurr1-RXR heterodimers mediate RXR ligand-induced signaling in neuronal cells

    Authors: Åsa Wallén‐Mackenzie, Alexander Mata de Urquiza, Susanna Petersson, Francisco Javier Rodríguez, Stina Friling, Joseph Wagner, Peter Ordentlich, Johan Lengqvist, Richard A. Heyman, Ernest Arenas, Thomas Perlmann - Genes & Development 2003 cited by 140

  22. Identification and Characterization of a Versatile Retinoid Response Element (Retinoic Acid Receptor Response Element-Retinoid X Receptor Response Element) in the Mouse Tissue Transglutaminase Gene Promoter

    Authors: László Nagy, Margaret Saydak, Nancy Jo Shipley, Shan Lu, James P. Basilion, Zhong Yan, Peter M. Syka, Roshantha A.S. Chandraratna, Joseph P. Stein, Richard A. Heyman, Peter J. Davies - Journal of Biological Chemistry 1996 cited by 126

  23. Identification of the Antineoplastic Agent 6-Mercaptopurine as an Activator of the Orphan Nuclear Hormone Receptor Nurr1

    Authors: Peter Ordentlich, Yingzhuo Yan, Sihong Zhou, Richard A. Heyman - Journal of Biological Chemistry 2003 cited by 117

  24. Phytol metabolites are circulating dietary factors that activate the nuclear receptor RXR.

    Authors: Sutisak Kitareewan, Leo T. Burka, K B Tomer, Carol E. Parker, Leesa J. Deterding, Robert Stevens, Barry M. Forman, Dale E. Mais, Richard A. Heyman, Terry McMorris, Cary Weinberger - Molecular Biology of the Cell 1996 cited by 202