David L. Huso
Active 1998–2021
- 73
- Papers
- 18,724
- Citations
- 71
- h-index
- 73
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Biochemistry, Genetics and Molecular Biology56.7%
- Medicine31.9%
- Immunology and Microbiology5.3%
- Neuroscience1.7%
- Engineering0.8%
- Nursing0.8%
- Other2.8%
Topics
- Gut microbiota and health6.9%
- Cancer Research and Treatments3.1%
- Connective tissue disorders research2.2%
- Clostridium difficile and Clostridium perfringens research2%
- Aortic Disease and Treatment Approaches1.8%
- Cancer, Hypoxia, and Metabolism1.6%
- Other82.4%
Coauthors
- Cynthia L. Sears11
- Shaoguang Wu10
- Xinqun Wu10
- Baktiar Karim9
- Bert Vogelstein9
- Franck Housseau9
- Kenneth W. Kinzler8
- Harry C. Dietz7
- Linda Resar7
- Drew M. Pardoll6
- Guosheng Liu6
- Ian Cheong6
- Amy Belton5
- Chetan Bettegowda5
- Djahida Bedja5
- Gregory G. Germino5
- Jennifer Habashi5
- Long H. Dang5
- Luis A. Díaz5
- Shervin Rabizadeh5
- Christina E. DeStefano Shields4
- Christine Gan4
- Daniel P. Judge4
- Elizabeth C. Wick4
All papers
- Patients with familial adenomatous polyposis harbor colonic biofilms containing tumorigenic bacteria
Authors: Christine M. Dejea, Payam Fathi, John M. Craig, Annemarie Boleij, Rahwa Taddese, Abby L. Geis, Xinqun Wu, Christina E. DeStefano Shields, Elizabeth M. Hechenbleikner, David L. Huso, Robert A. Anders, Francis M. Giardiello, Elizabeth C. Wick, Hao Wang, Shaoguang Wu, Drew M. Pardoll, Franck Housseau, Cynthia L. Sears - Science 2018 cited by 1,140
- A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses
Authors: Shaoguang Wu, Ki‐Jong Rhee, Emilia Albesiano, Shervin Rabizadeh, Xinqun Wu, Hung‐Rong Yen, David L. Huso, Frederick L. Brancati, Elizabeth Wick, Florencia McAllister, Franck Housseau, Drew M. Pardoll, Cynthia L. Sears - Nature Medicine 2009 cited by 1,784
- Bacteroides fragilis Toxin Coordinates a Pro-carcinogenic Inflammatory Cascade via Targeting of Colonic Epithelial Cells
Authors: Liam Chung, Erik Thiele Orberg, Abby L. Geis, June L. Chan, Kai Fu, Christina E. DeStefano Shields, Christine M. Dejea, Payam Fathi, Jie Chen, Benjamin B. Finard, Ada Tam, Florencia McAllister, Hongni Fan, Xinqun Wu, Sudipto Ganguly, Andriana Lebid, Paul Metz, Sara W. Van Meerbeke, David L. Huso, Elizabeth C. Wick, Drew M. Pardoll, Fengyi Wan, Shaoguang Wu, Cynthia L. Sears, Franck Housseau - Cell Host & Microbe 2018 cited by 635
- Polyamine catabolism contributes to enterotoxigenic Bacteroides fragilis -induced colon tumorigenesis
Authors: Andrew C. Goodwin, Christina E. DeStefano Shields, Shaoguang Wu, David L. Huso, Xinqun Wu, Tracy Murray Stewart, Amy Hacker‐Prietz, Shervin Rabizadeh, Patrick M. Woster, Cynthia L. Sears, Robert A. Casero - National Academy of Sciences, Proceedings of the National Academy of Sciences 2011 cited by 597
- Intratumoral injection of Clostridium novyi -NT spores induces antitumor responses
Authors: Nicholas J. Roberts, Linping Zhang, Filip Jankú, Amanda Collins, Ren-Yuan Bai, Verena Staedtke, Anthony Rusk, David Tung, Maria Miller, Jeffrey J. Roix, Kristen V. Khanna, Ravi Murthy, Robert S. Benjamin, Thorunn Helgason, Ariel D. Szvalb, Justin E. Bird, Sinchita Roy‐Chowdhuri, Halle H. Zhang, Yuan Qiao, Baktiar Karim, Jennifer S. McDaniel, Amanda Elpiner, Alexandra Sahora, Joshua L. Lachowicz, Brenda Phillips, Avenelle I. Turner, Mary K. Klein, Gerald Post, Luis A. Díaz, Gregory J. Riggins, Nickolas Papadopoulos, Kenneth W. Kinzler, Bert Vogelstein, Chetan Bettegowda, David L. Huso, Mary Varterasian, Saurabh Saha, Shibin Zhou - Science Translational Medicine 2014 cited by 395
- Combination bacteriolytic therapy for the treatment of experimental tumors
Authors: Long H. Dang, Chetan Bettegowda, David L. Huso, Kenneth W. Kinzler, Bert Vogelstein - National Academy of Sciences, Proceedings of the National Academy of Sciences 2001 cited by 562
- Losartan, an AT1 Antagonist, Prevents Aortic Aneurysm in a Mouse Model of Marfan Syndrome
Authors: Jennifer Habashi, Daniel P. Judge, Tammy M. Holm, Ronald D. Cohn, Bart Loeys, Timothy K. Cooper, Loretha Myers, Erin C. Klein, Guosheng Liu, Carla L. Calvi, Megan Podowski, Enid Neptune, Marc K. Halushka, Djahida Bedja, Kathleen Gabrielson, Daniel B. Rifkin, Luca Carta, Francesco Ramirez, David L. Huso, Harry C. Dietz - Science 2006 cited by 1,797
- Mutant PIK3CA promotes cell growth and invasion of human cancer cells
Authors: Yardena Samuels, Luis A. Díaz, Oleg Schmidt‐Kittler, Jordan M. Cummins, Laura J. DeLong, Ian Cheong, Carlo Rago, David L. Huso, Christoph Lengauer, Kenneth W. Kinzler, Bert Vogelstein, Victor E. Velculescu - Cancer Cell 2005 cited by 919
- Regulatory T-cell Response to Enterotoxigenic Bacteroides fragilis Colonization Triggers IL17-Dependent Colon Carcinogenesis
Authors: Abby L. Geis, Hongni Fan, Xinqun Wu, Shaoguang Wu, David L. Huso, Jaime L. Wolfe, Cynthia L. Sears, Drew M. Pardoll, Franck Housseau - Cancer Discovery 2015 cited by 192
- Bacteriolytic therapy can generate a potent immune response against experimental tumors
Authors: Nishant Agrawal, Chetan Bettegowda, Ian Cheong, Jean-François H. Geschwind, Charles G. Drake, Edward L. Hipkiss, Mitsuaki Tatsumi, Long H. Dang, Luis A. Díaz, Martin G. Pomper, Mohammad Abusedera, Richard L. Wahl, Kenneth W. Kinzler, Shibin Zhou, David L. Huso, Bert Vogelstein - National Academy of Sciences, Proceedings of the National Academy of Sciences 2004 cited by 299
- Evidence for a critical contribution of haploinsufficiency in the complex pathogenesis of Marfan syndrome
Authors: Daniel P. Judge, Nancy Jensen Biery, Douglas R. Keene, Jessica Geubtner, Loretha Myers, David L. Huso, Lynn Y. Sakai, Harry C. Dietz - Journal of Clinical Investigation 2004 cited by 396
- Induction of Persistent Colitis by a Human Commensal, EnterotoxigenicBacteroides fragilis, in Wild-Type C57BL/6 Mice
Authors: Ki‐Jong Rhee, Shaoguang Wu, Xinqun Wu, David L. Huso, Baktiar Karim, Augusto A. Franco, Shervin Rabizadeh, Jonathan E. Golub, Lauren E. Mathews, Jai W. Shin, R. Balfour Sartor, Douglas T. Golenbock, Abdel Rahim A. Hamad, Christine Gan, Franck Housseau, Cynthia L. Sears - Infection and Immunity 2009 cited by 287
- Angiotensin II–dependent TGF-β signaling contributes to Loeys-Dietz syndrome vascular pathogenesis
Authors: Elena Gallo, David Loch, Jennifer Habashi, Juan F. Calderón, Yi‐Chun Chen, Djahida Bedja, Christel van Erp, Elizabeth E. Gerber, Sarah J. Parker, Kimberly Sauls, Daniel P. Judge, Sara K. Cooke, Mark E. Lindsay, Rosanne Rouf, Loretha Myers, Colette M ap Rhys, Kathleen C. Kent, Russell A. Norris, David L. Huso, Harry C. Dietz - Journal of Clinical Investigation 2013 cited by 250
- Overcoming the hypoxic barrier to radiation therapy with anaerobic bacteria
Authors: Chetan Bettegowda, Long H. Dang, Ross A. Abrams, David L. Huso, Larry E. Dillehay, Ian Cheong, Nishant Agrawal, Scott Borzillary, J. Michael McCaffery, Elizabeth Watson, Kuo‐Shyan Lin, Fred Bunz, Kwamena E. Baidoo, Martin G. Pomper, Kenneth W. Kinzler, Bert Vogelstein, Shibin Zhou - National Academy of Sciences, Proceedings of the National Academy of Sciences 2003 cited by 169
- Stat3 Activation in Murine Colitis Induced by Enterotoxigenic Bacteroides fragilis
Authors: Elizabeth C. Wick, Shervin Rabizadeh, Emilia Albesiano, Xinqun Wu, Shaoguang Wu, June L. Chan, Ki‐Jong Rhee, Guillermo J. Ortega, David L. Huso, Drew M. Pardoll, Franck Housseau, Cynthia L. Sears - Inflammatory Bowel Diseases 2014 cited by 116
- A deleterious gene-by-environment interaction imposed by calcium channel blockers in Marfan syndrome
Authors: Jefferson J. Doyle, Alexander Doyle, Nicole K Wilson, Jennifer Habashi, Djahida Bedja, Ryan E Whitworth, Mark E. Lindsay, Florian Schoenhoff, Loretha Myers, Nick Huso, Suha Bachir, Oliver Squires, Benjamin Rusholme, Hamid Ehsan, David L. Huso, Craig J. Thomas, Mark J. Caulfield, Jennifer E. Van Eyk, Daniel P. Judge, Harry C. Dietz - eLife 2015 cited by 117
- Impaired physiological responses to chronic hypoxia in mice partially deficient for hypoxia-inducible factor 1α
Authors: Aimee Y. Yu, Larissa A. Shimoda, Narayan V. Iyer, David L. Huso, Xing Sun, Rita McWilliams, Terri H. Beaty, James S.K. Sham, Charles Wiener, J. T. Sylvester, Gregg L. Semenza - Journal of Clinical Investigation 1999 cited by 655
- A critical developmental switch defines the kinetics of kidney cyst formation after loss of Pkd1
Authors: Klaus Piontek, Luís F. Menezes, Miguel A. García-González, David L. Huso, Gregory G. Germino - Nature Medicine 2007 cited by 421
- Short Telomeres, even in the Presence of Telomerase, Limit Tissue Renewal Capacity
Authors: Ling-Yang Hao, Mary Armanios, Margaret A. Strong, Baktiar Karim, David M. Feldser, David L. Huso, Carol W. Greider - Cell 2005 cited by 307
- Radioimmunotherapy of Breast Cancer Metastases with α-Particle Emitter 225Ac: Comparing Efficacy with 213Bi and 90Y
Authors: Hong Song, Robert F. Hobbs, Ravy K. Vajravelu, David L. Huso, Caroline Esaias, Christos Apostolidis, Aliyah Morgenstern, George Sgouros - Cancer Research 2009 cited by 156
- Enterotoxigenic Bacteroides fragilis: A potential instigator of colitis
Authors: Shervin Rabizadeh, Ki‐Jong Rhee, Shaoguang Wu, David L. Huso, Christine Gan, Jonathan E. Golub, Xinqun Wu, Ming Zhang, Cynthia L. Sears - Inflammatory Bowel Diseases 2007 cited by 146
- Pharmacologic and Toxicologic Evaluation of C. novyi-NT Spores
Authors: Luis A. Díaz, Ian Cheong, Catherine A. Foss, Xiaosong Zhang, Brock A. Peters, Nishant Agrawal, Chetan Bettegowda, Baktiar Karim, Guosheng Liu, Khalid M. Khan, Xin Huang, Manu Kohli, Long H. Dang, Paul M. Hwang, Ahava Vogelstein, Elizabeth Garrett‐Mayer, Barry Kobrin, Martin G. Pomper, Shibin Zhou, Kenneth W. Kinzler, Bert Vogelstein, David L. Huso - Toxicological Sciences 2005 cited by 116
- G-protein coupled receptor 35 (GPR35) regulates the colonic epithelial cell response to enterotoxigenic Bacteroides fragilis
Authors: Annemarie Boleij, Payam Fathi, W. Brian Dalton, Ben Park, Xinqun Wu, David L. Huso, Jawara Allen, Sepideh Besharati, Robert A. Anders, Franck Housseau, Amanda E. Mackenzie, Laura Jenkins, Graeme Milligan, Shaoguang Wu, Cynthia L. Sears - Communications Biology 2021 cited by 46
- P53-induced microRNA-107 inhibits HIF-1 and tumor angiogenesis
Authors: Munekazu Yamakuchi, Craig Lotterman, Clare Bao, Ralph H. Hruban, Baktiar Karim, Joshua T. Mendell, David L. Huso, Charles J. Lowenstein - National Academy of Sciences, Proceedings of the National Academy of Sciences 2010 cited by 433
