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Gregg L. Semenza

Active 1984–2025

314
Papers
146,119
Citations
184
h-index
311
i10-index

Citations

Citations per year for Gregg L. Semenza1945: 2 citations1970: 1 citations1978: 1 citations1984: 2 citations1987: 1 citations1988: 1 citations1989: 23 citations1990: 5 citations1991: 18 citations1992: 13 citations1993: 47 citations1994: 39 citations1995: 63 citations1996: 111 citations1997: 224 citations1998: 370 citations1999: 470 citations2000: 831 citations2001: 1,097 citations2002: 1,240 citations2003: 1,521 citations2004: 1,889 citations2005: 1,603 citations2006: 1,692 citations2007: 1,647 citations2008: 1,686 citations2009: 1,970 citations2010: 1,669 citations2011: 1,669 citations2012: 1,857 citations2013: 2,007 citations2014: 1,829 citations2015: 1,959 citations2016: 1,797 citations2017: 1,731 citations2018: 1,524 citations2019: 4,601 citations2020: 5,242 citations2021: 5,349 citations2022: 3,841 citations2023: 2,730 citations2024: 3,638 citations2025: 1,700 citations2026: 51 citations1946–1969: no citations, so these years are not shown1971–1977: no citations, so these years are not shown1979–1983: no citations, so these years are not shown1985–1986: no citations, so these years are not shown

Citation sources

Countries

World map of the countries and regions citing this authorUnited States: 11,209 citing papers, 27.3% of this breakdownChina: 7,546 citing papers, 18.4% of this breakdownUnited Kingdom: 2,269 citing papers, 5.5% of this breakdownGermany: 1,945 citing papers, 4.8% of this breakdownItaly: 1,533 citing papers, 3.7% of this breakdownJapan: 1,419 citing papers, 3.5% of this breakdownCanada: 1,255 citing papers, 3.1% of this breakdownFrance: 1,146 citing papers, 2.8% of this breakdownSouth Korea: 907 citing papers, 2.2% of this breakdownIndia: 828 citing papers, 2% of this breakdownSpain: 808 citing papers, 2% of this breakdownAustralia: 792 citing papers, 1.9% of this breakdown
0%27.3%Other 22.8%

Institutions

Fields

  • Biochemistry, Genetics and Molecular Biology54.4%
  • Medicine31.2%
  • Immunology and Microbiology5.2%
  • Engineering2.8%
  • Neuroscience2.5%
  • Environmental Science0.9%
  • Other3%

Topics

  • Cancer, Hypoxia, and Metabolism12.2%
  • Mitochondrial Function and Pathology2.6%
  • RNA modifications and cancer2.4%
  • Epigenetics and DNA Methylation2.2%
  • Angiogenesis and VEGF in Cancer2.1%
  • Immune cells in cancer1.9%
  • Other76.6%

Coauthors

All papers

Open in search
  1. Hypoxia-Inducible Factors in Physiology and Medicine

    Authors: Gregg L. Semenza - Cell 2012 cited by 3,564

  2. HIF-1-mediated expression of pyruvate dehydrogenase kinase: A metabolic switch required for cellular adaptation to hypoxia

    Authors: Jung‐whan Kim, Irina Tchernyshyov, Gregg L. Semenza, Chi V. Dang - Cell Metabolism 2006 cited by 3,876

  3. Targeting HIF-1 for cancer therapy

    Authors: Gregg L. Semenza - Nature reviews. Cancer 2003 cited by 6,700

  4. Hypoxia-inducible factors: cancer progression and clinical translation

    Authors: Elizabeth E. Wicks, Gregg L. Semenza - Journal of Clinical Investigation 2022 cited by 551

  5. Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension.

    Authors: G L Wang, Bing‐Hua Jiang, E A Rue, Gregg L. Semenza - National Academy of Sciences, Proceedings of the National Academy of Sciences 1995 cited by 6,211

  6. Hypoxia and the extracellular matrix: drivers of tumour metastasis

    Authors: Daniele M. Gilkes, Gregg L. Semenza, Denis Wirtz - Nature reviews. Cancer 2014 cited by 1,545

  7. Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression

    Authors: Anne Le, Charles R. Cooper, Arvin M. Gouw, Ramani Dinavahi, Anirban Maitra, Lorraine M. Deck, Robert E. Royer, David L. Vander Jagt, Gregg L. Semenza, Chi V. Dang - National Academy of Sciences, Proceedings of the National Academy of Sciences 2010 cited by 1,504

  8. Control of TH17/Treg Balance by Hypoxia-Inducible Factor 1

    Authors: Eric V. Dang, Joseph Barbi, Huang‐Yu Yang, Dilini Jinasena, Hong Yu, Ying Zheng, Zachary Bordman, Juan Fu, Young Kim, Hung‐Rong Yen, Weibo Luo, Karen Zeller, Larissa A. Shimoda, Suzanne L. Topalian, Gregg L. Semenza, Chi V. Dang, Drew M. Pardoll, Fan Pan - Cell 2011 cited by 1,588

  9. Pyruvate Kinase M2 Is a PHD3-Stimulated Coactivator for Hypoxia-Inducible Factor 1

    Authors: Weibo Luo, Hongxia Hu, Ryan Chang, Jun Zhong, Matthew Knabel, Robert N. O’Meally, Robert N. Cole, Akhilesh Pandey, Gregg L. Semenza - Cell 2011 cited by 1,464

  10. HIF-1 mediates metabolic responses to intratumoral hypoxia and oncogenic mutations

    Authors: Gregg L. Semenza - Journal of Clinical Investigation 2013 cited by 1,310

  11. Hypoxia-Inducible Factors: Master Regulators of Cancer Progression

    Authors: Luana Schito, Gregg L. Semenza - Trends in cancer 2016 cited by 1,013

  12. Hypoxia-inducible factors: mediators of cancer progression and targets for cancer therapy

    Authors: Gregg L. Semenza - Trends in Pharmacological Sciences 2012 cited by 1,518

  13. Hypoxia induces the breast cancer stem cell phenotype by HIF-dependent and ALKBH5-mediated m 6 A-demethylation of NANOG mRNA

    Authors: Chuanzhao Zhang, Debangshu Samanta, Haiquan Lu, John W. Bullen, Huimin Zhang, Ivan Chen, Xiaoshun He, Gregg L. Semenza - National Academy of Sciences, Proceedings of the National Academy of Sciences 2016 cited by 1,014

  14. HIF-1 and mechanisms of hypoxia sensing

    Authors: Gregg L. Semenza - Current Opinion in Cell Biology 2001 cited by 1,285

  15. Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1α

    Authors: Narayan V. Iyer, Lori E. Kotch, Faton Agani, Sandra W. Leung, Erik Laughner, Roland H. Wenger, Max Gassmann, John D. Gearhart, Ann M. Lawler, Aimee Y. Yu, Gregg L. Semenza - Genes & Development 1998 cited by 2,479

  16. Oxygen Sensing, Hypoxia-Inducible Factors, and Disease Pathophysiology

    Authors: Gregg L. Semenza - Annual Review of Pathology Mechanisms of Disease 2013 cited by 1,187

  17. HIF-1: upstream and downstream of cancer metabolism

    Authors: Gregg L. Semenza - Current Opinion in Genetics & Development 2009 cited by 1,352

  18. Hypoxia Response Elements in the Aldolase A, Enolase 1, and Lactate Dehydrogenase A Gene Promoters Contain Essential Binding Sites for Hypoxia-inducible Factor 1

    Authors: Gregg L. Semenza, Bing‐Hua Jiang, Sandra W. Leung, Rosa Passantino, Jean‐Paul Concordet, Pascal Maire, Agata Giallongo - Journal of Biological Chemistry 1996 cited by 1,765

  19. HIF-1 Regulates Cytochrome Oxidase Subunits to Optimize Efficiency of Respiration in Hypoxic Cells

    Authors: Ryo Fukuda, Huafeng Zhang, Jung‐whan Kim, Larissa A. Shimoda, Chi V. Dang, Gregg L. Semenza - Cell 2007 cited by 1,224

  20. Activation of Vascular Endothelial Growth Factor Gene Transcription by Hypoxia-Inducible Factor 1

    Authors: Jo A. Forsythe, Bing‐Hua Jiang, Narayan V. Iyer, Faton Agani, Sandra W. Leung, Robert D. Koos, Gregg L. Semenza - Molecular and Cellular Biology 1996 cited by 3,969

  21. Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics

    Authors: Gregg L. Semenza - Oncogene 2009 cited by 1,700

  22. HIF-1 regulates CD47 expression in breast cancer cells to promote evasion of phagocytosis and maintenance of cancer stem cells

    Authors: Huimin Zhang, Haiquan Lu, Lisha Xiang, John W. Bullen, Chuanzhao Zhang, Debangshu Samanta, Daniele M. Gilkes, Jianjun He, Gregg L. Semenza - National Academy of Sciences, Proceedings of the National Academy of Sciences 2015 cited by 432

  23. Hypoxia-inducible factors and RAB22A mediate formation of microvesicles that stimulate breast cancer invasion and metastasis

    Authors: Ting Wang, Daniele M. Gilkes, Naoharu Takano, Lisha Xiang, Weibo Luo, Corey J. Bishop, Pallavi Chaturvedi, Jordan J. Green, Gregg L. Semenza - National Academy of Sciences, Proceedings of the National Academy of Sciences 2014 cited by 485

  24. Mitochondrial Autophagy Is an HIF-1-dependent Adaptive Metabolic Response to Hypoxia

    Authors: Huafeng Zhang, Marta Bosch‐Marcé, Larissa A. Shimoda, Yee Sun Tan, Jin Hyen Baek, Jacob Wesley, Frank J. Gonzalez, Gregg L. Semenza - Journal of Biological Chemistry 2008 cited by 1,577