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Denis Wirtz

Active 1994–2025

162
Papers
28,672
Citations
94
h-index
149
i10-index

Citations

Citations per year for Denis Wirtz1996: 1 citations1998: 14 citations1999: 29 citations2000: 68 citations2001: 75 citations2002: 99 citations2003: 90 citations2004: 177 citations2005: 152 citations2006: 188 citations2007: 177 citations2008: 212 citations2009: 263 citations2010: 247 citations2011: 256 citations2012: 233 citations2013: 281 citations2014: 312 citations2015: 345 citations2016: 333 citations2017: 365 citations2018: 326 citations2019: 979 citations2020: 1,110 citations2021: 1,092 citations2022: 925 citations2023: 710 citations2024: 1,067 citations2025: 629 citations2026: 26 citations1997: no citations, so this year is not shown

Citation sources

Countries

World map of the countries and regions citing this authorUnited States: 3,617 citing papers, 31.9% of this breakdownChina: 1,523 citing papers, 13.4% of this breakdownGermany: 762 citing papers, 6.7% of this breakdownUnited Kingdom: 649 citing papers, 5.7% of this breakdownFrance: 470 citing papers, 4.1% of this breakdownItaly: 321 citing papers, 2.8% of this breakdownCanada: 301 citing papers, 2.7% of this breakdownNetherlands: 287 citing papers, 2.5% of this breakdownSpain: 279 citing papers, 2.5% of this breakdownJapan: 272 citing papers, 2.4% of this breakdownAustralia: 225 citing papers, 2% of this breakdownSwitzerland: 215 citing papers, 1.9% of this breakdown
0%31.9%Other 21.4%

Institutions

Fields

  • Biochemistry, Genetics and Molecular Biology56.3%
  • Medicine18.5%
  • Engineering6.7%
  • Materials Science4.4%
  • Neuroscience3%
  • Immunology and Microbiology2.5%
  • Other8.6%

Topics

  • Cellular Mechanics and Interactions10%
  • 3D Printing in Biomedical Research4%
  • Cancer Cells and Metastasis3.2%
  • Cancer, Hypoxia, and Metabolism2.3%
  • Cell Adhesion Molecules Research1.9%
  • Microtubule and mitosis dynamics1.9%
  • Other76.7%

Coauthors

All papers

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  1. Extracellular vesicles in immunomodulation and tumor progression

    Authors: Carolyn Marar, Bartholomew Starich, Denis Wirtz - Nature Immunology 2021 cited by 592

  2. Hypoxia and the extracellular matrix: drivers of tumour metastasis

    Authors: Daniele M. Gilkes, Gregg L. Semenza, Denis Wirtz - Nature reviews. Cancer 2014 cited by 1,545

  3. A comparison of methods to assess cell mechanical properties

    Authors: Pei-Hsun Wu, Dikla Raz-Ben Aroush, Atef Asnacios, Wei-Chiang Chen, Maxim Dokukin, Bryant L. Doss, Pauline Durand-Smet, Andrew Ekpenyong, Jochen Guck, Nataliia Guz, Paul A. Janmey, Jerry Lee, Nicole M. Moore, Albrecht Ott, Yeh-Chuin Poh, Robert Ros, Mathias Sander, Igor Sokolov, Jack R. Staunton, Ning Wang, Graeme Whyte, Denis Wirtz - Nature Methods 2018 cited by 689

  4. The physics of cancer: the role of physical interactions and mechanical forces in metastasis

    Authors: Denis Wirtz, Κωνσταντίνος Κωνσταντόπουλος, Peter C. Searson - Nature reviews. Cancer 2011 cited by 1,354

  5. Micro- and macrorheology of mucus

    Authors: Samuel K. Lai, Yingying Wang, Denis Wirtz, Justin Hanes - Advanced Drug Delivery Reviews 2009 cited by 1,216

  6. CODA: quantitative 3D reconstruction of large tissues at cellular resolution

    Authors: Ashley Kiemen, Alicia M. Braxton, Mia P. Grahn, Kyu Sang Han, Jaanvi Mahesh Babu, Rebecca Reichel, Ann Chenyu Jiang, Bridgette Kim, Jocelyn Y. Hsu, Falone Amoa, Sashank Reddy, Seung‐Mo Hong, Toby C. Cornish, Elizabeth D. Thompson, Peng Huang, Laura D. Wood, Ralph H. Hruban, Denis Wirtz, Pei-Hsun Wu - Nature Methods 2022 cited by 180

  7. Transient Opening of the Mitochondrial Permeability Transition Pore Induces Microdomain Calcium Transients in Astrocyte Processes

    Authors: Amit Agarwal, Pei-Hsun Wu, Ethan G. Hughes, Masahiro Fukaya, Max A. Tischfield, Abraham J. Langseth, Denis Wirtz, Dwight E. Bergles - Neuron 2017 cited by 464

  8. 3D genomic mapping reveals multifocality of human pancreatic precancers

    Authors: Alicia M. Braxton, Ashley L. Kiemen, Mia P. Grahn, André Forjaz, Jeeun Parksong, Jaanvi Mahesh Babu, Jiaying Lai, Lily Zheng, Noushin Niknafs, Liping Jiang, Haixia Cheng, Qianqian Song, Rebecca Reichel, Sarah Graham, Alexander Damanakis, Catherine G. Fischer, Stephanie Mou, Cameron Metz, Julie Granger, Xiao-Ding Liu, Niklas Bachmann, Yutong Zhu, Yunzhou Liu, Cristina Almagro-Pérez, Ann Chenyu Jiang, Jeonghyun Yoo, Bridgette Kim, Scott Du, Eli Foster, Jocelyn Y. Hsu, Paula Andreu Rivera, Linda C. Chu, Fengze Liu, Elliot K. Fishman, Alan L. Yuille, Nicholas J. Roberts, Elizabeth D. Thompson, Robert B. Scharpf, Toby C. Cornish, Yuchen Jiao, Rachel Karchin, Ralph H. Hruban, Pei-Hsun Wu, Denis Wirtz, Laura D. Wood - Nature, Nat. 2024 cited by 134

  9. Water Permeation Drives Tumor Cell Migration in Confined Microenvironments

    Authors: Kimberly M. Stroka, Hongyuan Jiang, Shih-Hsun Chen, Ziqiu Tong, Denis Wirtz, Sean X. Sun, Κωνσταντίνος Κωνσταντόπουλος - Cell 2014 cited by 557

  10. Single-cell morphology encodes metastatic potential

    Authors: Pei-Hsun Wu, Daniele M. Gilkes, Jude M. Phillip, Akshay Narkar, Thomas W. Cheng, Jorge A. Marchand, Meng-Horng Lee, Rong Li, Denis Wirtz - Science Advances 2020 cited by 208

  11. The Mechanobiology of Aging

    Authors: Jude M. Phillip, Ivie Aifuwa, Jeremy Walston, Denis Wirtz - Annual Review of Biomedical Engineering 2015 cited by 306

  12. Three-dimensional matrix fiber alignment modulates cell migration and MT1-MMP utility by spatially and temporally directing protrusions

    Authors: Stephanie I. Fraley, Pei-Hsun Wu, Lijuan He, Yunfeng Feng, Ranjini Krisnamurthy, Gregory D. Longmore, Denis Wirtz - Scientific Reports 2015 cited by 244

  13. A robust unsupervised machine-learning method to quantify the morphological heterogeneity of cells and nuclei

    Authors: Jude M. Phillip, Kyu Sang Han, Wei-Chiang Chen, Denis Wirtz, Pei-Hsun Wu - Nature Protocols 2021 cited by 129

  14. Particle-Tracking Microrheology of Living Cells: Principles and Applications

    Authors: Denis Wirtz - Annual Review of Biophysics 2009 cited by 677

  15. A perinuclear actin cap regulates nuclear shape

    Authors: Shyam B. Khatau, Christopher M. Hale, Phillip J. Stewart-Hutchinson, Meet S. Patel, Colin L. Stewart, Peter C. Searson, Didier Hodzic, Denis Wirtz - National Academy of Sciences, Proceedings of the National Academy of Sciences 2009 cited by 605

  16. Hypoxia-inducible factor 1 is a master regulator of breast cancer metastatic niche formation

    Authors: Carmen Chak‐Lui Wong, Daniele M. Gilkes, Huafeng Zhang, Jasper Chen, Hong Wei, Pallavi Chaturvedi, Stephanie I. Fraley, Chun‐Ming Wong, US Khoo, Irene Oi‐Lin Ng, Denis Wirtz, Gregg L. Semenza - National Academy of Sciences, Proceedings of the National Academy of Sciences 2011 cited by 435

  17. Hypoxia-inducible Factor 1 (HIF-1) Promotes Extracellular Matrix Remodeling under Hypoxic Conditions by Inducing P4HA1, P4HA2, and PLOD2 Expression in Fibroblasts

    Authors: Daniele M. Gilkes, Saumendra Bajpai, Pallavi Chaturvedi, Denis Wirtz, Gregg L. Semenza - Journal of Biological Chemistry 2013 cited by 481

  18. Nuclear lamin A/C harnesses the perinuclear apical actin cables to protect nuclear morphology

    Authors: Jeong-Ki Kim, Arghavan Louhghalam, Geonhui Lee, Benjamin W. Schafer, Denis Wirtz, Dong‐Hwee Kim - Nature Communications 2017 cited by 198

  19. Focal adhesion size uniquely predicts cell migration

    Authors: Dong‐Hwee Kim, Denis Wirtz - The FASEB Journal 2012 cited by 362

  20. PanIN and CAF transitions in pancreatic carcinogenesis revealed with spatial data integration

    Authors: Alexander T.F. Bell, Jacob T. Mitchell, Ashley Kiemen, Melissa R. Lyman, Kohei Fujikura, Jae W. Lee, Erin M. Coyne, Sarah M. Shin, Sushma Nagaraj, Atul Deshpande, Pei‐Hsun Wu, Dimitrios N. Sidiropoulos, Rossin Erbe, Jacob Stern, Rena Chan, Stephen R. Williams, James M. Chell, Lauren Ciotti, Jacquelyn W. Zimmerman, Denis Wirtz, Won Jin Ho, Neeha Zaidi, Elizabeth D. Thompson, Elizabeth M. Jaffee, Laura D. Wood, Elana J. Fertig, Luciane T. Kagohara - Cell Systems 2024 cited by 51

  21. Reversible Hydrogels from Self-Assembling Artificial Proteins

    Authors: Wendy A. Petka, James L. Harden, Kevin P. McGrath, Denis Wirtz, David A. Tirrell - Science 1998 cited by 1,081

  22. A distinctive role for focal adhesion proteins in three-dimensional cell motility

    Authors: Stephanie I. Fraley, Yunfeng Feng, Ranjini Krishnamurthy, Dong Hwee Kim, Alfredo Celedon, Gregory D. Longmore, Denis Wirtz - Nature Cell Biology 2010 cited by 587

  23. Particle Tracking Microrheology of Complex Fluids

    Authors: Thomas G. Mason, Kathirvel Ganesan, John H. van Zanten, Denis Wirtz, Scot C. Kuo - Physical Review Letters 1997 cited by 872

  24. Confinement Sensing and Signal Optimization via Piezo1/PKA and Myosin II Pathways

    Authors: Wei-Chien Hung, Jessica R. Yang, Christopher L. Yankaskas, Bin Sheng Wong, Pei-Hsun Wu, Carlos Pardo-Pastor, Selma A. Serra, Meng‐Jung Chiang, Zhizhan Gu, Denis Wirtz, Miguel A. Valverde, Joy T. Yang, Jin Zhang, Κωνσταντίνος Κωνσταντόπουλος - Cell Reports 2016 cited by 169