litlas
Log inCreate account

David M. Valenzuela

Active 1982–2016

72
Papers
30,301
Citations
71
h-index
71
i10-index

Citations

Citations per year for David M. Valenzuela1983: 1 citations1986: 1 citations1991: 14 citations1992: 77 citations1993: 114 citations1994: 99 citations1995: 81 citations1996: 92 citations1997: 122 citations1998: 120 citations1999: 128 citations2000: 122 citations2001: 91 citations2002: 100 citations2003: 104 citations2004: 125 citations2005: 124 citations2006: 204 citations2007: 244 citations2008: 393 citations2009: 447 citations2010: 494 citations2011: 508 citations2012: 501 citations2013: 538 citations2014: 530 citations2015: 536 citations2016: 460 citations2017: 427 citations2018: 337 citations2019: 1,078 citations2020: 1,025 citations2021: 934 citations2022: 678 citations2023: 470 citations2024: 685 citations2025: 272 citations2026: 6 citations1984–1985: no citations, so these years are not shown1987–1990: no citations, so these years are not shown

Citation sources

Countries

World map of the countries and regions citing this authorUnited States: 5,488 citing papers, 34% of this breakdownChina: 1,496 citing papers, 9.3% of this breakdownGermany: 1,103 citing papers, 6.8% of this breakdownUnited Kingdom: 1,025 citing papers, 6.3% of this breakdownJapan: 645 citing papers, 4% of this breakdownItaly: 615 citing papers, 3.8% of this breakdownFrance: 609 citing papers, 3.8% of this breakdownCanada: 556 citing papers, 3.4% of this breakdownAustralia: 396 citing papers, 2.5% of this breakdownSwitzerland: 365 citing papers, 2.3% of this breakdownSpain: 340 citing papers, 2.1% of this breakdownNetherlands: 315 citing papers, 1.9% of this breakdown
0%34%Other 19.8%

Institutions

Fields

  • Biochemistry, Genetics and Molecular Biology37.3%
  • Medicine36.2%
  • Neuroscience12.4%
  • Immunology and Microbiology11.3%
  • Psychology1.2%
  • Agricultural and Biological Sciences0.5%
  • Other1.1%

Topics

  • Muscle Physiology and Disorders3.8%
  • Sirtuins and Resveratrol in Medicine3.7%
  • Adipose Tissue and Metabolism2.7%
  • Immune Cell Function and Interaction2.2%
  • Autophagy in Disease and Therapy2.1%
  • Cancer-related molecular mechanisms research1.8%
  • Other83.7%

Coauthors

All papers

Open in search
  1. Identification of Ubiquitin Ligases Required for Skeletal Muscle Atrophy

    Authors: Sue C. Bodine, Esther Latres, Susanne Baumhueter, Venus Lai, Lorna Nuñez, Brian Clarke, William Poueymirou, Frank J. Panaro, Erqian Na, Kumar Dharmarajan, Zhen‐Qiang Pan, David M. Valenzuela, Thomas M. DeChiara, Trevor N. Stitt, George D. Yancopoulos, David J. Glass - Science 2001 cited by 3,526

  2. Mice with megabase humanization of their immunoglobulin genes generate antibodies as efficiently as normal mice

    Authors: Andrew Murphy, Lynn E. Macdonald, Sean Stevens, Margaret Karow, Anthony Doré, Kevin J. Pobursky, Tammy Huang, William Poueymirou, Lakeisha Esau, Melissa Meola, Warren R. Mikulka, Pamela Krueger, Jeanette Fairhurst, David M. Valenzuela, Nicholas Papadopoulos, George D. Yancopoulos - National Academy of Sciences, Proceedings of the National Academy of Sciences 2014 cited by 451

  3. Genomic Instability and Aging-like Phenotype in the Absence of Mammalian SIRT6

    Authors: Raúl Mostoslavsky, Katrin F. Chua, David B. Lombard, Wendy W. Pang, Miriam R. Fischer, Lionel Gellon, Pingfang Liu, Gustavo Mostoslavsky, Sonia Franco, Michael Murphy, Kevin D. Mills, Parin Patel, Joyce T. Hsu, Andrew L. Hong, Ethan Ford, Hwei-Ling Cheng, Caitlin Kennedy, Nomelí P. Núñez, Roderick T. Bronson, David Frendewey, Wojtek Auerbach, David M. Valenzuela, Margaret Karow, Michael O. Hottiger, Stephen D. Hursting, J. Carl Barrett, Leonard Guarente, Richard Mulligan, Bruce Demple, George D. Yancopoulos, Frederick W. Alt - Cell 2006 cited by 1,636

  4. SIRT4 Inhibits Glutamate Dehydrogenase and Opposes the Effects of Calorie Restriction in Pancreatic β Cells

    Authors: Marcia C. Haigis, Raúl Mostoslavsky, Kevin M. Haigis, Kamau Fahie, Danos C. Christodoulou, Andrew Murphy, David M. Valenzuela, George D. Yancopoulos, Margaret Karow, Gil Blander, Cynthia Wolberger, Tomas A. Prolla, Richard Weindruch, Frederick W. Alt, Leonard Guarente - Cell 2006 cited by 1,157

  5. Precise and in situ genetic humanization of 6 Mb of mouse immunoglobulin genes

    Authors: Lynn E. Macdonald, Margaret Karow, Sean Stevens, Wojtek Auerbach, William Poueymirou, Jason Yasenchak, David Frendewey, David M. Valenzuela, Cosmas Giallourakis, Frederick W. Alt, George D. Yancopoulos, Andrew Murphy - National Academy of Sciences, Proceedings of the National Academy of Sciences 2014 cited by 385

  6. Mammalian Sir2 Homolog SIRT3 Regulates Global Mitochondrial Lysine Acetylation

    Authors: David B. Lombard, Frederick W. Alt, Hwei-Ling Cheng, Jakob Bunkenborg, Ryan S. Streeper, Raúl Mostoslavsky, Jennifer Kim, George D. Yancopoulos, David M. Valenzuela, Andrew Murphy, Yinhua Yang, Yaohui Chen, Matthew D. Hirschey, Roderick T. Bronson, Marcia C. Haigis, Leonard Guarente, Robert V. Farese, Sherman M. Weissman, Eric Verdin, Bjoern Schwer - Molecular and Cellular Biology 2007 cited by 1,216

  7. Innate and Adaptive Interleukin-22 Protects Mice from Inflammatory Bowel Disease

    Authors: Lauren A. Zenewicz, George D. Yancopoulos, David M. Valenzuela, Andrew Murphy, Sean Stevens, Richard A. Flavell - Immunity 2008 cited by 796

  8. IL-22BP is regulated by the inflammasome and modulates tumorigenesis in the intestine

    Authors: Samuel Huber, Nicola Gagliani, Lauren A. Zenewicz, Francis J. Huber, Lidia Bosurgi, Bo Hu, Matija Hedl, Wei Zhang, William O’Connor, Andrew Murphy, David M. Valenzuela, George D. Yancopoulos, Carmen J. Booth, Judy H. Cho, Wenjun Ouyang, Clara Abraham, Richard A. Flavell - Nature 2012 cited by 712

  9. Atypical angiopoietin-like protein that regulates ANGPTL3

    Authors: Fabiana Quagliarini, Yan Wang, Julia Kozlitina, Nick V. Grishin, Rhonda Hyde, Eric Boerwinkle, David M. Valenzuela, Andrew Murphy, Jonathan C. Cohen, Helen H. Hobbs - National Academy of Sciences, Proceedings of the National Academy of Sciences 2012 cited by 456

  10. Regulation of the Germinal Center Response by MicroRNA-155

    Authors: To‐Ha Thai, Dinis Pedro Calado, Stefano Casola, K. Mark Ansel, Changchun Xiao, Yingzi Xue, Andrew Murphy, David Frendewey, David M. Valenzuela, Jeffery L. Kutok, Marc Schmidt‐Supprian, Nikolaus Rajewsky, George D. Yancopoulos, Anjana Rao, Klaus Rajewsky - Science 2007 cited by 1,482

  11. SIRT7 Represses Myc Activity to Suppress ER Stress and Prevent Fatty Liver Disease

    Authors: Jiyung Shin, Ming He, Yufei Liu, Silvana Paredes, Lidia Villanova, Katharine Brown, Xiaolei Qiu, Noushin Nabavi, Mary Mohrin, Kathleen Wojnoonski, Patrick Li, Hwei-Ling Cheng, Andrew Murphy, David M. Valenzuela, Hanzhi Luo, Pankaj Kapahi, Ronald M. Krauss, Raúl Mostoslavsky, George D. Yancopoulos, Frederick W. Alt, Katrin F. Chua, Danica Chen - Cell Reports 2013 cited by 282

  12. Mice completely lacking immunoproteasomes show major changes in antigen presentation

    Authors: Eleanor Kincaid, Jenny W Che, Ian A. York, Hernando Escobar, Eduardo Reyes‐Vargas, Julio C. Delgado, Raymond M. Welsh, Margaret Karow, Andrew Murphy, David M. Valenzuela, George D. Yancopoulos, Kenneth L. Rock - Nature Immunology 2011 cited by 287

  13. ANGPTL3 blockade with a human monoclonal antibody reduces plasma lipids in dyslipidemic mice and monkeys

    Authors: Viktoria Gusarova, Corey A. Alexa, Yan Wang, Ashique Rafique, Jee Hae Kim, David G. Buckler, Ivory J. Mintah, Lisa M. Shihanian, Jonathan C. Cohen, Helen H. Hobbs, Yurong Xin, David M. Valenzuela, Andrew Murphy, George D. Yancopoulos, Jesper Gromada - Journal of Lipid Research 2015 cited by 212

  14. The Receptor Tyrosine Kinase MuSK Is Required for Neuromuscular Junction Formation In Vivo

    Authors: Thomas M. DeChiara, David C. Bowen, David M. Valenzuela, Mary Simmons, William Poueymirou, Susan E. Thomas, Erika Kinetz, Debra Compton, Eduardo Rojas, John S. Park, Cynthia L. Smith, Peter S. DiStefano, David J. Glass, Steven J. Burden, George D. Yancopoulos - Cell 1996 cited by 916

  15. RORγ-Expressing Th17 Cells Induce Murine Chronic Intestinal Inflammation via Redundant Effects of IL-17A and IL-17F

    Authors: Moritz Leppkes, Christoph Becker, Ivaylo I. Ivanov, Sebastian Hirth, Stefan Wirtz, Clemens Neufert, Sandrine Pouly, Andrew Murphy, David M. Valenzuela, George D. Yancopoulos, Burkhard Becher, Dan R. Littman, Markus F. Neurath - Gastroenterology 2008 cited by 450

  16. Interleukin-22 but Not Interleukin-17 Provides Protection to Hepatocytes during Acute Liver Inflammation

    Authors: Lauren A. Zenewicz, George D. Yancopoulos, David M. Valenzuela, Andrew Murphy, Margaret Karow, Richard A. Flavell - Immunity 2007 cited by 618

  17. During muscle atrophy, thick, but not thin, filament components are degraded by MuRF1-dependent ubiquitylation

    Authors: Shenhav Cohen, Jeffrey J. Brault, Steven P. Gygi, David J. Glass, David M. Valenzuela, Carlos A. Gartner, Esther Latres, Alfred L. Goldberg - The Journal of Cell Biology 2009 cited by 583

  18. Slitrk5 deficiency impairs corticostriatal circuitry and leads to obsessive-compulsive–like behaviors in mice

    Authors: Sergey V. Shmelkov, Adı́lia Hormigo, Deqiang Jing, Catia C Proenca, Kevin G. Bath, Till Milde, Evgeny Shmelkov, Jared S Kushner, Muhamed Baljević, Iva Dincheva, Andrew Murphy, David M. Valenzuela, Nicholas W. Gale, George D. Yancopoulos, Ipe Ninan, Francis S. Lee, Shahin Rafii - Nature Medicine 2010 cited by 361

  19. Multiple knockout mouse models reveal lincRNAs are required for life and brain development

    Authors: Martin Sauvageau, Loyal A. Goff, Simona Lodato, Boyan Bonev, Abigail F. Groff, Chiara Gerhardinger, Diana B. Sanchez-Gomez, Ezgi Hacisuleyman, Eric V. Li, Matthew Spence, Stephen C. Liapis, William Mallard, Michael Morse, Mavis R. Swerdel, Michael F D’Ecclessis, Jennifer C. Moore, Venus Lai, Guochun Gong, George D. Yancopoulos, David Frendewey, Manolis Kellis, Ronald P. Hart, David M. Valenzuela, Paola Arlotta, John L. Rinn - eLife 2013 cited by 699

  20. Efficient differentiation and function of human macrophages in humanized CSF-1 mice

    Authors: Chozhavendan Rathinam, William Poueymirou, José Rojas, Andrew Murphy, David M. Valenzuela, George D. Yancopoulos, Anthony Rongvaux, Elizabeth E. Eynon, Markus G. Manz, Richard A. Flavell - Blood 2011 cited by 164

  21. Broad CTL response is required to clear latent HIV-1 due to dominance of escape mutations

    Authors: Kai Deng, Mihaela Pertea, Anthony Rongvaux, Leyao Wang, Christine M. Durand, Gabriel Ghiaur, Jun Lai, Holly McHugh, Haiping Hao, Hao Zhang, Joseph B. Margolick, Cagan Gurer, Andrew Murphy, David M. Valenzuela, George D. Yancopoulos, Steven G. Deeks, Till Strowig, Priti Kumar, Janet D. Siliciano, Steven L. Salzberg, Richard A. Flavell, Liang Shan, Robert F. Siliciano - Nature 2015 cited by 501

  22. The mammalian gene function resource: the international knockout mouse consortium

    Authors: Allan Bradley, Konstantinos Anastassiadis, A. Ayadi, James F. Battey, Cindy Bell, Marie‐Christine Birling, Joanna Bottomley, Steve D. M. Brown, Antje Bürger, Carol J. Bult, Wendy Bushell, Francis S. Collins, Christian Desaintes, Brendan Doe, Aris N. Economides, Janan T. Eppig, Richard H. Finnell, Colin Fletcher, Martin Fray, David Frendewey, Roland H. Friedel, Frank Grosveld, Jens Hansen, Yann Hérault, Geoffrey G. Hicks, Andreas Hörlein, Richard Houghton, Martin Hrabě de Angelis, Danny Huylebroeck, Vivek Iyer, Pieter J. de Jong, James A. Kadin, Cornelia Kaloff, Karen L. Kennedy, Manousos Koutsourakis, K. C. Kent Lloyd, Susan Marschall, Jeremy Mason, Colin McKerlie, Michael P. McLeod, Harald von Melchner, Mark W. Moore, Alejandro O. Mujica, András Nagy, Mikhail Nefedov, Lauryl M. J. Nutter, Guillaume Pavlovic, Jane L. Peterson, Jonathan D. Pollock, Ramiro Ramírez‐Solis, Derrick E. Rancourt, Marcello Raspa, Jacques Remacle, Martin Ringwald, Barry P. Rosen, Nadia Rosenthal, Janet Rossant, Patricia Ruíz, Edward J. Ryder, Joel Schick, Frank Schnütgen, Paul N. Schofield, Claudia Seisenberger, Mohammed Selloum, Elizabeth M. Simpson, William C. Skarnes, Damian Smedley, William L. Stanford, A. Francis Stewart, Kevin Stone, Kate Swan, Hamsa D. Tadepally, Lydia Teboul, Glauco P. Tocchini‐Valentini, David M. Valenzuela, Anthony P. West, Ken‐ichi Yamamura, Yuko Yoshinaga, Wolfgang Wurst - Mammalian Genome 2012 cited by 328

  23. C9orf72 ablation causes immune dysregulation characterized by leukocyte expansion, autoantibody production and glomerulonephropathy in mice

    Authors: Amanda Atanasio, Vilma Decman, Derek W. R. White, Meg Ferrell Ramos, Burcin Ikiz, Hoi-Ching Lee, Chia-Jen Siao, Susannah Brydges, Elizabeth LaRosa, Yu Bai, Wen Fury, Patricia Burfeind, Ralica Zamfirova, Gregg Warshaw, Jamie Orengo, A. Oyejide, Michael Fralish, Wojtek Auerbach, William Poueymirou, Jan Freudenberg, Guochun Gong, Brian Zambrowicz, David M. Valenzuela, George D. Yancopoulos, Andrew Murphy, Gavin Thurston, Ka‐Man Venus Lai - Scientific Reports 2016 cited by 265

  24. EphA2 promotes infiltrative invasion of glioma stem cells in vivo through cross-talk with Akt and regulates stem cell properties

    Authors: Hui Miao, Nickolas W. Gale, Hong Guo, Juan Qian, Aaron Petty, Justin R. Kaspar, Andrew Murphy, David M. Valenzuela, George D. Yancopoulos, Dolores Hambardzumyan, Justin D. Lathia, Jeremy N. Rich, Joonsung Lee, Binghe Wang - Oncogene 2014 cited by 175